Dlim010363.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila limbata
Gene Symbol
RREB1
Assembly
GCA_963924055.1
Location
OZ001351.1:31747144-31754020[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.038 3.8 8.8 0.8 1 21 258 278 258 280 0.93
2 13 0.00035 0.035 15.2 0.2 1 23 290 312 290 312 0.98
3 13 8.5e-05 0.0086 17.1 7.3 1 23 318 340 318 340 0.98
4 13 0.72 72 4.7 2.4 2 20 560 578 560 580 0.93
5 13 0.038 3.9 8.7 0.1 1 23 736 758 736 758 0.97
6 13 1.3e-05 0.0013 19.7 0.7 1 23 768 790 768 790 0.99
7 13 0.00087 0.088 13.9 2.0 1 23 796 819 796 819 0.97
8 13 0.0031 0.31 12.2 2.0 1 23 1093 1116 1093 1116 0.95
9 13 9.1e-05 0.0091 17.0 0.3 2 23 1465 1486 1464 1486 0.97
10 13 0.15 15 6.9 6.3 1 23 1492 1515 1492 1515 0.97
11 13 4.7 4.7e+02 2.2 3.6 1 23 1647 1670 1647 1670 0.79
12 13 0.0088 0.89 10.7 0.5 3 23 1730 1750 1728 1750 0.96
13 13 0.0014 0.14 13.3 4.8 1 23 1756 1778 1756 1778 0.99

Sequence Information

Coding Sequence
ATGCTGGccacacaacagcaacagcaacaacaacaacacacaacaacaactgttgctgctgcaacaacaacgacagcagcagcggcagcaacaacagttgcacACAGCAGCGATGCCAGCGTCGACATGGATCGCCAGCGTCGCGACTCAACCACCTCAGAATCCTCGCTGGAGCATCTCGACTTGGGCCGCACACCAAAGAagctcagcagcagcagcggagCGCCGCAGCCGACGTCGACGCCGCACGACACAACAACGACGTCTACGACGGCGACGTCGCGCAAGCGCAAgctgcggcagcagcagcagcaacaacatttgctCTCCGATGACgatgagcagcaacaacaacaacagctggaTCTGTCTGCGCAGCGACCGCGTCACAAGCAGCGACGCAGCGCCAACGCTGCTGCAGCCAGCGCCAGCATTGTCGTCGATTACAGCGCCAGCGGCGACGCCAGTTCGCTGCGTAAAAAGTTTCGACTGAATCGTAGCAGCGTCGTCGGCAGCGGCGTTAACGGCGAACTCTCCGAATCGGGTTTCGTTGATGGCAGCGCTCATAGCGGTTATTTGCTCAGCAGCAGCGCCGGCAGCAGCGCACAGTCAGCGTCGGCAGcggttgcagcagcagcagcagcagcagccgcagttGCAGCAGCGCAGCAGGCGTCAGCGTCAAGCAGTTCGGGCGGCTCGTCACCTCAAGGCCTGTCGTGCCTGTCGAGCGCCGAATCGGGAATCGGCGCCGGCGAAGATCACATGAAATACTTGTGCCCCATCTGTGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATACGTTGCCACAATTATGCCAACGGCGACACTGAGAATTTCACCTGCCGCATCTGCTCAAAGGTGTTGTCGTCGGCCTCGTCGCTGGACAGACACGTGCTGGTGCACACGGGAGAGCGACCGTTCAACTGCCGTTATTGCCACTTGACATTCACGACGAACGGCAACATGCATCGTCACATGCGAACACACAAGCAACATCagacacagcagcagcaacagtcgcaatcgctgcagcagcaacaacagtcacagtcacagcaacaacagtcgcagtcacagcagcaacagcgacgtCAGCAACATGCGACGGCAACAGCAATTGGCGCACAGGCGGCGGGTGGCAGATCCGAGAGTTATGAGAGTGATGCAAGTTGCTCAACGGATGTGTCCAGTGCACAAagtcacagcagcaacagcagcagcagcaatcattccaacaacaacaacaataacaagctcagcaacaacaacaacaacaacaatgaggaggaggaggagaaggagcagcagcaacatgttgttgctgccacaattTGTGGCAAGCAGCGACGCCATAAAatcaacattaacaacaacaacataatgGACAAAGAAGACCAGGAGCAGCCGCAGGAGGAGGACGCTGAGAGTGATGTGGAGAGCGTGGAGGATGTGGCACAATTGATAACCTCCACGCCCGATGTGGCAACGCTGCTTGCCTCCTCCGGTGGCACGTCACCGAGTCAATCCCCAGCACCGCCACCAatgatgctgctgctcaaTTGTCCCGCCTGCGAGGCGGATGATTTTGAATCCTTGCCCGCGTTGTGGCAACATTTGGATGCCCAGCATGCGGATATACCCGCCAAGTGCCGGGAGTGCGAGGTTATCTTTGCCAGTCATCGCCAGCTGCAGACGCACAGTTGCCGCGGTGTCAACGGGCTGCAAATGTTGCCACTGCTGGCGGCCAGTTCAAGTCCCAAACACGAAATCGAGCCGGACGAAGAGGAGGACGAAGAGGAGGAGCAGCAGGAGGATGAGGACATGGAGATGCAGCAGGAGGAGCAAgtgcatcagcaacaacacacagaACGCGATGAGTTCTTTCAGCAGCTGTACAACAAGAGTAAAACCAATCTTGTTGCGCCCTCGTTGCCCTCACCGATCAAACATGAACTGGCCACAGATCGCGGCGATTCGCGACAGGATTTGGCGGACATTCAAAGCATCCTGAACATGACCAGCTCCAGCTGCACCTCCAGTTTCCTGCGCAACTTTGAGCAATCGGTGAACACGCCCTGCTCCAGTCAGTACAGCCTGGACGGTCGCGATGGCGACGAGGAGGCCCAGGATGCATTTACCAGTGAGTTTCGGCGAATGAAATTGCGCGGCGAATTTCCGTGCAAATTGTGCGTGGCCGTGTTTCCCAATCTGCGTGCCTTGAAGGGACACAATCGCGTCCACTTGGCGGCCGTGGGTCCCGCCGGTCCCTTCAGGTGCAACATGTGTCCCTACGCGGTCTGCGACAAGGCGGCGCTGGTACGGCACATGCGCACCCACAACGGGGACCGTCCCTATGAGTGTGCCGTGTGCAATTATGCATTCACCACCAAGGCCAATTGCGAGCGACATTTGCGCAATCGTCACAGCAAAACGAGTCGCGAGGATGTTAAGCGTGCCATTGTCTATCATCCGGCGGAGGATGCCAGCTGTGATGACTCCAAGTCCGGTCAGAGATTGAATGATTCGGATTTGGGTGAGCTCAGTTATCGCTCCATGTCGCCCACTGTGGAGCCAGCATCGCAATTGAAGCACATGTTGCTGGCGgagtcaacaacagcagcaacagcgactgTTGCTCCAGCAACAcctattgttgctgctgtcggcAAGACGGCTCCTTCCAAGATTCAAGTCAAGAGCTTGGATCAGTTGGTGGACAAACCATTGGCGCCTGCTTTGGATCTCAGCATGGATGTTTTGGATCTGAGCAAAAAGGAGCGACCACAGGAATTGccgcaggagcagcagcagcaacagcagcagcaacgcgAGCAACGCGAACGCGAGCGTGAATTGCTGCTgtgtcagcaacaacagcagcagcagcaacagcagcagcagcaactttttGGCGCTGGCGATGCTGCCACGCAGTACATGCAACAGCTGTTTCGCAATCTCATGTTCCAGCAATCGCCGGCATTTCCGTTCTTCAGCTTTATGCCGCCAACAACCGCTGACAAAAAcaccgcagcaacagcagccgcgCTGCccgcaacggcagcaacagctgctgttAAGCCAACAACAAACGCTGCCTTGGGCCTGCCCCTGCCACTGCCCGTTGTGGGCGGCGTCGGCGTGGGCGTGCCCGTGCCTGCGGGCGGACCCGTCAAAATGGTCATCAAAAATGGCGTCCTGATgccaaagcaaaagcaacgtCGCTATCGCACGGAGCGACCATTTGCCTGCGAGCACTGCTCGGCGAGATTCACGCTGCGCTCGAACATGGAGCGGCATGTGAAGCAGCAGCATCCGCAGTTCTATGCCCAGCGACAGCGCAGTGGACACCATGTGATGCGCGGACGCGGTGCATCCTCGAatgcagcggcagcagcagcggcggcagcagcagcagcagcggcagcaatgTCCAATCTGAGCCAGCAGCAACATGGACATCATGCGCATCACGCGCACATCTCGGATCAGGTGAAATATGCGATATTGGCACAGCAGTTGAAGGCACGCAAGGATACGGATCTGTTGCAGCAGGCGCTGGCACATGGCTCGAGCAGTGTGGCCGGCAATCCTCTCCAGCATTTTGGCTACAAGCaatacagcagcagcaacaacaacaacaacagcaatggtAATGGTAATCCCACCAATGGACATCATGTAGCTGACGATGATGAGCCCAAATTGATTATTGATGAGGATGATGAGCTGGAGGAGGACTTGGATGATGATTTAATGGAGGAGGACGAGGATGAGCTGGATGAGGAGCAGTCGGAACAGCAGGAGGAGGatcaggagcagcagcagcagcagcagttggaGCAACAGCCACCAAGAACTTCAACGCCCATTGAGGCGGCCAAAAAGGTGGCGGAAACCATTCTGGAGCAGGCCATCAAGGCGGGCAAGGACCAGAGCATAAAGTTGCCCACACcaactgccacgcccactcccaCAGCTACGCCCACGCCgacagccacgcccacacccACACCCACACCCACGGCCACGACAATGAAAACAATGATTGCCCAAGCGGAATCCGTGGCCAAATCCCTCAAAGAAGTTGCCAGCTCGCCGTTTAAAGATGAATCTCAAGATCTTGTGCCCGTCTCCAAACTGGTGGACAATGCCACCAGCAATCAGGTGAGCTTCAATAGCTACTTTCGGCCCAGCGATGTGGCCAACCACATGGAGCAATCCGATGAGGAGGGTCTCGTGGCCTCCGGCAGTGCGAGCGAGAGCAACAATTCCGGCACCGAGGACGtgaccagcagcagcagcagcagcaacgagcCCAAAAAGAAATCCGCCTACAGTCTGGCTCCCAATCGCGTCAGTTGTCCCTATTGCCAGCGCATGTTCCCCTGGAGCAGCAGCTTGAGGCGTCACATCCTGACGCACACCGGGCAGAAGCCCTTCAAGTGCTCCCATTGTCCACTGCTGTTTACCACGAAGAGCAATTGCGATCGTCATTTGCTAAGGAAACATGGCAATGTGGAGAGTGCGATGAGTGTTTATGTGCCCACGGAGGATGTGAGTGAACCGATACCAGTGCCCAAATCTGTGGAGGAGATTGAGCTGGAGGAGCAGCGGCGACGCAAGGCGGAGCAGCtggagagagaaagggagcgGGAGCTGGAGCGGGAGCGcaagagggagagggagttggagttggagagGGAGCGAGAGCGGGAACTGGAGCGGGAGCGGGAGcgggagcagcaacagcagcaacagctcaTCCAGCAATTGGCAGCAGCGGCACAAATGGTTGCCGCCTCCGTCGCCGCCAACAACTCCGCCGCCTCCGCCGCCTCCTCCCCTCCTGGAGCAGCACCCGGCGCCAACAGTCCCGGGGAAACCCAGGGCAGCGATTTGCCCTACAAGTGTCATCTCTGTGAATATTCGTTTGGCGAGCGTCTGCAATGCTTGGAGCACATTAAGCAACAACATGCACACGAGTTTGCTTTACTCCTGGCCAAAGGTGCCATTGAAACGGAGGAGCAACCGTTgccagcaccagcagcagcagcagcagcagcagcaacagttgcctcCGATGAGGACTCCGGACATGCCACACGTGCCACAAATGTCAAATATCCCGATTATAGCAATCGCAAAGTGATTTGTGCCTTTTGTGTGCGTCGCTTTTGGTCCACGGAGGATTTGAGGCGTCACATGAGAACTCACTCTGGGGAGCGTCCATTTCAGTGCGAGATTTGCTTGAGGAAATTCACACTGAAGCACAGCATGCTGCGGCACATGAAGAAGCACAGTGGACGCGCCCATAACGGTGATTTGGGTGGACAATCCGATTGCTCGGATGATGAGcagtctgccacgcctcccaGCACGCCCACGCCCATGATAATGCCACAAgcgaacaacaataacaataacaacacttgtcacaataacaacaacaataacaacaacaacaacaacagtaaacaAAGCTTACGTTTGCCGAAATTACATGAATTGTTGGACAAGGCGAATGAATGGCGCGTGAGTCGTTCATGTGAACACAAGGAAAACATTGCTGAATCTGCCACACCATCGGCAGCAACTGCcacagccgcagcagcagcagctgttgccgTTGCAAGCGGCGATTTAATTGGCAATTTGTTGGGCATAAGTGATCAAGGTATACTCAATAAGTTGCTTTCCTCCGCAGACGAGGCAGCTAAGCTACTAGGCGTTGACAAGTAa
Protein Sequence
MLATQQQQQQQQHTTTTVAAATTTTAAAAATTVAHSSDASVDMDRQRRDSTTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHDTTTTSTTATSRKRKLRQQQQQQHLLSDDDEQQQQQQLDLSAQRPRHKQRRSANAAAASASIVVDYSASGDASSLRKKFRLNRSSVVGSGVNGELSESGFVDGSAHSGYLLSSSAGSSAQSASAAVAAAAAAAAAVAAAQQASASSSSGGSSPQGLSCLSSAESGIGAGEDHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTQQQQQSQSLQQQQQSQSQQQQSQSQQQQRRQQHATATAIGAQAAGGRSESYESDASCSTDVSSAQSHSSNSSSSNHSNNNNNNKLSNNNNNNNEEEEEKEQQQHVVAATICGKQRRHKININNNNIMDKEDQEQPQEEDAESDVESVEDVAQLITSTPDVATLLASSGGTSPSQSPAPPPMMLLLNCPACEADDFESLPALWQHLDAQHADIPAKCRECEVIFASHRQLQTHSCRGVNGLQMLPLLAASSSPKHEIEPDEEEDEEEEQQEDEDMEMQQEEQVHQQQHTERDEFFQQLYNKSKTNLVAPSLPSPIKHELATDRGDSRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGDEEAQDAFTSEFRRMKLRGEFPCKLCVAVFPNLRALKGHNRVHLAAVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHSKTSREDVKRAIVYHPAEDASCDDSKSGQRLNDSDLGELSYRSMSPTVEPASQLKHMLLAESTTAATATVAPATPIVAAVGKTAPSKIQVKSLDQLVDKPLAPALDLSMDVLDLSKKERPQELPQEQQQQQQQQREQRERERELLLCQQQQQQQQQQQQQLFGAGDAATQYMQQLFRNLMFQQSPAFPFFSFMPPTTADKNTAATAAALPATAATAAVKPTTNAALGLPLPLPVVGGVGVGVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGASSNAAAAAAAAAAAAAAAMSNLSQQQHGHHAHHAHISDQVKYAILAQQLKARKDTDLLQQALAHGSSSVAGNPLQHFGYKQYSSSNNNNNSNGNGNPTNGHHVADDDEPKLIIDEDDELEEDLDDDLMEEDEDELDEEQSEQQEEDQEQQQQQQLEQQPPRTSTPIEAAKKVAETILEQAIKAGKDQSIKLPTPTATPTPTATPTPTATPTPTPTPTATTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVSKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSSNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAEQLERERERELERERKRERELELERERERELEREREREQQQQQQLIQQLAAAAQMVAASVAANNSAASAASSPPGAAPGANSPGETQGSDLPYKCHLCEYSFGERLQCLEHIKQQHAHEFALLLAKGAIETEEQPLPAPAAAAAAAATVASDEDSGHATRATNVKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRAHNGDLGGQSDCSDDEQSATPPSTPTPMIMPQANNNNNNNTCHNNNNNNNNNNNSKQSLRLPKLHELLDKANEWRVSRSCEHKENIAESATPSAATATAAAAAAVAVASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00585429;
90% Identity
iTF_00602041;
80% Identity
-