Dsub018043.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila suboccidentalis
Gene Symbol
-
Assembly
GCA_037043435.1
Location
JBAMBK010002596.1:154476-159091[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.0018 0.13 13.0 2.0 1 23 210 232 210 232 0.96
2 26 4e-05 0.0029 18.2 1.0 1 23 238 260 238 260 0.98
3 26 0.096 7 7.6 1.3 2 23 292 313 291 313 0.96
4 26 0.017 1.2 9.9 3.3 1 23 388 411 388 411 0.94
5 26 9.3 6.8e+02 1.3 4.2 2 23 423 446 422 446 0.92
6 26 0.17 12 6.8 2.2 1 23 452 474 452 474 0.97
7 26 0.18 13 6.7 0.4 2 23 493 514 492 514 0.96
8 26 0.0015 0.11 13.2 2.9 1 23 590 612 590 613 0.95
9 26 0.032 2.3 9.1 0.1 1 22 622 643 622 643 0.95
10 26 0.19 14 6.7 5.7 1 23 652 675 652 675 0.95
11 26 0.00011 0.0084 16.8 0.2 2 23 704 725 703 725 0.97
12 26 6.4e-06 0.00046 20.7 3.5 1 23 733 755 733 755 0.99
13 26 0.49 36 5.3 1.0 1 23 906 929 906 929 0.95
14 26 0.21 16 6.5 2.3 1 21 936 956 936 957 0.93
15 26 0.099 7.2 7.5 0.5 1 23 966 989 966 989 0.91
16 26 1.2e-05 0.00088 19.8 1.9 1 23 1014 1036 1014 1036 0.97
17 26 0.00015 0.011 16.4 0.9 1 23 1043 1065 1043 1065 0.98
18 26 0.014 0.99 10.2 0.0 2 20 1092 1110 1091 1112 0.93
19 26 0.014 1 10.2 3.9 1 23 1157 1180 1157 1180 0.96
20 26 0.014 1 10.2 0.5 1 23 1217 1240 1217 1240 0.96
21 26 0.0011 0.078 13.7 3.5 1 23 1262 1285 1262 1285 0.97
22 26 1.5e-05 0.0011 19.5 0.1 2 23 1313 1334 1312 1334 0.95
23 26 0.00026 0.019 15.7 3.1 1 23 1340 1362 1340 1362 0.99
24 26 2.5e-06 0.00018 22.0 2.0 1 23 1368 1390 1368 1390 0.97
25 26 6.4e-08 4.7e-06 27.0 2.4 1 23 1396 1418 1396 1418 0.99
26 26 0.0011 0.08 13.7 0.2 1 21 1424 1444 1424 1448 0.91

Sequence Information

Coding Sequence
ATGTTTCCGACCGATATTTGCCGCACATGTGCTCTACAGGATGTAAATTTGTTAGCGCTCTCAACGTACACCGAGAAATATGCAAACAAAAGTTTCCACGACATGTTGCATGAGTTGACACAAAACGATCCCCTAATGGAACATTCAGACGACAATCTGCCCCAGCATTTGTGTGGCGACTGCTTGCGTAAGCTGGAAGAGGCCTATGCATTTGTGCTGCAAGCTCGTCAGGTGCAGGAGCAACTGTTGCACAGAATACGCAAGGGACTGCAGTGTCTGGATGAGACGCCCATAGACATAGCCCCAGAGCACATAAAGACAGAAACAGACGTTGCCTTGGAGCCAGCCAAGGACGGACACAATGTGGAAAAAGTGGCAGCTGTGCCTGTTGCAGCCTTAAAGATGCAGCCGGAAAGTGAGACCGACAGCAGCCCGGCGGATGCGGCCGACGATGATGTGCTAGACCTTAAACCTTCACAGCTGAGACGCAGCAATCGGAAGACAAAGCTTGGAACAGACAGCGACAATGAAGCAGATTGTGAAAAGTCCAGCGCAATGCCGCTCAAGCGTCGTCGCGGTCGTCCTGCACGTAAGCCCAAAATGGAAGCTATCAACAAGGACGGACGCCACGCGTGCGAGGTGTGCGGCAAGACGTTTTCGTGGCATCGCGACATGCAACGCCACGCTCGCGTCCACTTCGAGCAGGCTGGCTATGTGTGCGACAGCTGTGGCAAGGGATTTATCCGCAAGGACAAGTACATGTACCATTTGCGATCGCACGAGAAGCGCCAAGCCAAGCGGCAGGCTCTTCAGCTGGGCAACGAGTGGCGCTTTGCGGAACGTCTGTACAGCTCGGGACGCCTCAAGCGTGTGGAGTGTAAGCTGTGCGGCCTGAAATGCCAGCGGATTCAGGAACTTCGTGAGCATCTGACCAGCCATGTTAGCATTGAAACATTGTCGAATCTCTGCGCCGATAGCGATGTTATCATGGAACAGTTTAACGGCCAGCAGCTGGACTTGATGCAGATTAAGCAACAAGTGTGTGCGGACATAGCCAAGGGAAGAGATCACCTGGACAAATACTGTGTGGTGGTCAACGCACATGGCTATGAGCTTTGTCTGAGCGACTCGGACGAGGAATTGGCAGGAATGCCGCCTCCATACCAATGCCAACCTTGCAACACACACTTCTCACGCAAATATCGCCTGATGCGGCACACGCTTGAGGAGCACACTCAACCGACAACTGAGGCAACTCCCTGGCAACGTTGCAACCAGTGCCAAATTGGCTTCGTGTGCGTTAAGCTACTGGAACAGCATCAGCGCACACAGTGCCACAATCAGATGAAGCGCTATAGTTGTCCCAACTGTCCAGGCAAATTTATTTGGCGGCAGAACCTGCAGCATCATGCGTGCTCCCATCGCATGAGATGGTCAGAGGCACAGGATCAGGAGAGAAGTCAAAGCCGTCAGATTCAGTGCTGCCTTTGCGATGAGCAACTGCAAAGTATGTCGGCACTACGTGCCCATCTAGTAACTCATTGCGATGGACAAACCGGCATTGATCCTGATCGACGTTCTACCTTCTTTCGATGTAACTATCCCGATGGATCCACCTGCAACCAGACGGAGCTCAGCACACAAATAGCGAGGGACTTTGGGGCAGAGGATTATGGTCGCTACTTCAATGCCTGCACAGGCAGCGGCCAAGAGCTGGATTTCTTCGACTCCGATACGGATTTAAGCGATCAGTATGCCGCAGATGTCCATTCTTGTGATCTGTGTGGTGTGAGCACAAAACGCCTTGCCCAGCTCCTGAAGCATCAACAGAATCACCACAGTGAGGTGGATGACACACTGCCCCACGTGTGCGACAAGTGTGGATTGGGATTTGTGGCTGAACCGCTGCTTCGCCAGCATCGTCGACGCAGTTGTGCGAAGCGGCATGCAAAGTACCATTGTCAGCATTGCAGTCTCCATTTCATCTGGCAGTCCAACTACGAGCGACACATGGAACTGCAGCACGAGgcggagacagagacggatGATGTCGCTGGTAGTGTGCCCAATACCAGGCTAAGAAGCAAACGCCAACAAGCTGCCAAGCTACAGTGCAATGAATGTGAAAAGGTCTTCATCTGGCCAAAGGATTTGACGCGTCATAGGCGCATCCATCAGCCGCAGGCATCGGCACAGTACGAATGCAGCTACTGCGAGCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCCCACATGCGTGTCCACGGCGAGCAGCATTTGGATGCGGCGGTTGTGCCTAACAGCGATCCGGATCCGACGACATTACAGCGAATGCCAATGGTGTTGACGCAATTGTGCCAACCGAATGGATGCAAGCTGATCCAGTGCATGATCTGTCTCTCTCGGCACACCAAGATCTCTGATCTACGCATGCATTTGGTGAAGCATCAGTTTGCTGTGGAATTTGCGGAGGAGCGTGTCAAGCCGGAGAATATAGAGACTATATGCCGGGCTCTATATCCGGAGCAGGGGACTCTGCTGGATGAGCAACAATTAATTGAACGCATCCAGGCGGATGTGGGCATGGGCACTGAGCTGGAGAGATTCATTTCAATAACCAACGAGGCAGGCATTGAGCTTAGTCTGGACAGCAGCGAAACTGAAACGGATTCGGACTCAGCCGAAGTGgaaaggagcagcagcagaggacGACAATACTATTGTGATCTTTGCCAGCTGAACTGGCCACGTAAACATCAACTCTATGCCCACCAGCTGGAGCAGCATACATGGGAACAGGCAACACACGTTTGTACCCACTGTCAGGCCAGATTCATCAATGACCAGTTGCTGGATCATCACTATCGTAGTCTCTGTCGTAACGTCCACAAGCGTTTCCTCTGTCGAAAGTGTCCCTTAAGGTTTCGCTGGCGCGACAATCTGAAGCTGCACACGGACGTGGCGCATCAGGAAACAACTGGAGAGCAGACGAACTTGGGCATCCAATTGAATGGAGCCGGTCGCCTTCCTGTTGTCAGCTACGATTGTACCGAATGCAATCGCAGCttcaaaatgcaaaaggaTCTCACGAGGCACACACTAATGCATGCCCAGGAATCGAGCATTTATCGGTGTCGTTGGTGTGCCCGTCGCTTCTATCGTCAGGCCAATCTCCTGCAGCACATTGAGCGCCATGGAATCAATGCCACGCAGCTGCCCTACGCCGAGTCCCTGCTCAATGCCAGCCGTCATCCCCATGGCCCGAAGTGCATCCAATGCAAGGTGTGTGATATTCATTTTCCCACAATTGCCGCACTACGTTCCCATTTGGCGTCCACACCGAGCGGGACTCATCATGAAATTGGATCGATGCTCAACTACTCGATTACCAATCAGCTGGGCTATGAGCTGCACCTGGAGGACTCGGAAACGGATGAGGAGGCCAAGCCGCCTGGCATGCCCAGCCACTACACCTGCGGCATGTGCCAGCTGCGTTGTGTCCGCAAGTATGAGCTGCACCAGCATCAGCAGGCCATGCATCGATTGGAACGGATCACGGAGGGCTGTGATCAGTGCATCTATAAGAGCGTTTCCCCACATCTCATCGCCTACCATCGGCGTGTGCAATGTGGCAACACGGAGAAGCAATTCAAGTGCGTCAAATGCGGCTACAAGTTCATGTGGGAGTCAAATCTGCTGCTGCACATTCAATTGCAGCATCCCGGAAATGATGATACAGCAGCAGTGCCTGATCCAGAGACACCTGCAGTGGAGTCCCAGATCTTTCAGTGCGGTCAATGCCCGCGTAAATACAACCGCAAGGATCGACTGACAGCCCATGTAAAGAAGTGTCATGCACCTGGTGCAGTTGGTCCAACTGTTTCTCCAGCAAAAACATCAACGTCTTCAAGTGTCGCCAAGCAACAGAAAAGTTTTCTCTGCGCCTTTTGTGGCAAGGCGGTGAGCTCCTCCTCCAATCTCATTATACACATACGTCGCCATACCGGCGAGAAGCCCTTCAAGTGCGACTTCTGCGACATGGCCTTCCCCCGCTCCTCCGATCTGCAGTGCCATCGACGCACCCACACTGGCGAACGGCCACATGTCTGCACCGTGTGCCAAAAGGGATTCGCTCGCTCCTACAAGCTCCAGCAGCATATGCGCATCCACAATGGCGAACGTCCCTACAAGTGCACCTACTGCGACAAGAGCTTCACACAGTCCAACGATCTCACGCTCCACATTCGACGACACACCGGCGAGCGACCCTATCAATGTGACACCTGCGGGGAACGCTTCATTCAGGGCACAGCACTCAAGAACCATCGGCTACAGAATGGCCATTTCGGGACGGGGGATGGCCTAGCAAAGAATAATTAA
Protein Sequence
MFPTDICRTCALQDVNLLALSTYTEKYANKSFHDMLHELTQNDPLMEHSDDNLPQHLCGDCLRKLEEAYAFVLQARQVQEQLLHRIRKGLQCLDETPIDIAPEHIKTETDVALEPAKDGHNVEKVAAVPVAALKMQPESETDSSPADAADDDVLDLKPSQLRRSNRKTKLGTDSDNEADCEKSSAMPLKRRRGRPARKPKMEAINKDGRHACEVCGKTFSWHRDMQRHARVHFEQAGYVCDSCGKGFIRKDKYMYHLRSHEKRQAKRQALQLGNEWRFAERLYSSGRLKRVECKLCGLKCQRIQELREHLTSHVSIETLSNLCADSDVIMEQFNGQQLDLMQIKQQVCADIAKGRDHLDKYCVVVNAHGYELCLSDSDEELAGMPPPYQCQPCNTHFSRKYRLMRHTLEEHTQPTTEATPWQRCNQCQIGFVCVKLLEQHQRTQCHNQMKRYSCPNCPGKFIWRQNLQHHACSHRMRWSEAQDQERSQSRQIQCCLCDEQLQSMSALRAHLVTHCDGQTGIDPDRRSTFFRCNYPDGSTCNQTELSTQIARDFGAEDYGRYFNACTGSGQELDFFDSDTDLSDQYAADVHSCDLCGVSTKRLAQLLKHQQNHHSEVDDTLPHVCDKCGLGFVAEPLLRQHRRRSCAKRHAKYHCQHCSLHFIWQSNYERHMELQHEAETETDDVAGSVPNTRLRSKRQQAAKLQCNECEKVFIWPKDLTRHRRIHQPQASAQYECSYCERKFHRKDGLKSHMRVHGEQHLDAAVVPNSDPDPTTLQRMPMVLTQLCQPNGCKLIQCMICLSRHTKISDLRMHLVKHQFAVEFAEERVKPENIETICRALYPEQGTLLDEQQLIERIQADVGMGTELERFISITNEAGIELSLDSSETETDSDSAEVERSSSRGRQYYCDLCQLNWPRKHQLYAHQLEQHTWEQATHVCTHCQARFINDQLLDHHYRSLCRNVHKRFLCRKCPLRFRWRDNLKLHTDVAHQETTGEQTNLGIQLNGAGRLPVVSYDCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGINATQLPYAESLLNASRHPHGPKCIQCKVCDIHFPTIAALRSHLASTPSGTHHEIGSMLNYSITNQLGYELHLEDSETDEEAKPPGMPSHYTCGMCQLRCVRKYELHQHQQAMHRLERITEGCDQCIYKSVSPHLIAYHRRVQCGNTEKQFKCVKCGYKFMWESNLLLHIQLQHPGNDDTAAVPDPETPAVESQIFQCGQCPRKYNRKDRLTAHVKKCHAPGAVGPTVSPAKTSTSSSVAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDFCDMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCDTCGERFIQGTALKNHRLQNGHFGTGDGLAKNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00558059;
90% Identity
iTF_00601964; iTF_00533979; iTF_00585352;
80% Identity
-