Basic Information

Insect: Drosophila limbata
Gene Symbol: -
Assembly: GCA_963924055.1
Location: OZ001352.1:17427782-17432382[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0017 0.17 13.0 2.0 1 23 207 229 207 229 0.96

2 26 0.11 11 7.4 1.3 1 23 235 257 235 257 0.97

3 26 0.11 11 7.3 0.7 2 23 289 310 288 310 0.96

4 26 0.2 20 6.5 2.3 1 23 385 408 385 408 0.93

5 26 8.7 8.8e+02 1.3 4.2 2 23 420 443 419 443 0.92

6 26 0.65 66 4.9 1.3 1 20 449 468 449 470 0.93

7 26 0.088 8.9 7.6 0.6 2 23 490 511 489 511 0.97

8 26 0.00034 0.034 15.2 0.7 1 23 587 610 587 610 0.96

9 26 0.0013 0.13 13.3 0.4 1 22 619 640 619 640 0.95

10 26 0.05 5.1 8.4 3.7 1 23 649 672 649 672 0.95

11 26 0.00021 0.021 15.9 0.3 2 23 701 722 700 722 0.97

12 26 6e-06 0.0006 20.7 3.5 1 23 730 752 730 752 0.99

13 26 2.3 2.3e+02 3.2 2.6 1 23 902 925 902 925 0.94

14 26 0.2 20 6.5 2.3 1 21 932 952 932 953 0.93

15 26 0.016 1.6 9.9 0.7 1 23 962 985 962 985 0.93

16 26 1.1e-05 0.0011 19.9 1.9 1 23 1010 1032 1010 1032 0.97

17 26 0.00014 0.015 16.4 0.9 1 23 1039 1061 1039 1061 0.98

18 26 0.0039 0.39 11.9 0.1 2 20 1088 1106 1087 1108 0.93

19 26 0.013 1.3 10.2 3.9 1 23 1153 1176 1153 1176 0.96

20 26 0.043 4.4 8.6 0.4 1 23 1213 1236 1213 1236 0.96

21 26 0.00082 0.083 14.0 3.4 1 23 1258 1281 1258 1281 0.97

22 26 1.4e-05 0.0014 19.5 0.1 2 23 1309 1330 1308 1330 0.95

23 26 0.00083 0.084 14.0 3.0 1 23 1336 1358 1336 1358 0.99

24 26 2.4e-06 0.00024 22.0 2.0 1 23 1364 1386 1364 1386 0.97

25 26 6e-08 6.1e-06 27.0 2.4 1 23 1392 1414 1392 1414 0.99

26 26 0.001 0.1 13.7 0.2 1 21 1420 1440 1420 1444 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0017	0.17	13.0	2.0	1	23	207	229	207	229	0.96
2	26	0.11	11	7.4	1.3	1	23	235	257	235	257	0.97
3	26	0.11	11	7.3	0.7	2	23	289	310	288	310	0.96
4	26	0.2	20	6.5	2.3	1	23	385	408	385	408	0.93
5	26	8.7	8.8e+02	1.3	4.2	2	23	420	443	419	443	0.92
6	26	0.65	66	4.9	1.3	1	20	449	468	449	470	0.93
7	26	0.088	8.9	7.6	0.6	2	23	490	511	489	511	0.97
8	26	0.00034	0.034	15.2	0.7	1	23	587	610	587	610	0.96
9	26	0.0013	0.13	13.3	0.4	1	22	619	640	619	640	0.95
10	26	0.05	5.1	8.4	3.7	1	23	649	672	649	672	0.95
11	26	0.00021	0.021	15.9	0.3	2	23	701	722	700	722	0.97
12	26	6e-06	0.0006	20.7	3.5	1	23	730	752	730	752	0.99
13	26	2.3	2.3e+02	3.2	2.6	1	23	902	925	902	925	0.94
14	26	0.2	20	6.5	2.3	1	21	932	952	932	953	0.93
15	26	0.016	1.6	9.9	0.7	1	23	962	985	962	985	0.93
16	26	1.1e-05	0.0011	19.9	1.9	1	23	1010	1032	1010	1032	0.97
17	26	0.00014	0.015	16.4	0.9	1	23	1039	1061	1039	1061	0.98
18	26	0.0039	0.39	11.9	0.1	2	20	1088	1106	1087	1108	0.93
19	26	0.013	1.3	10.2	3.9	1	23	1153	1176	1153	1176	0.96
20	26	0.043	4.4	8.6	0.4	1	23	1213	1236	1213	1236	0.96
21	26	0.00082	0.083	14.0	3.4	1	23	1258	1281	1258	1281	0.97
22	26	1.4e-05	0.0014	19.5	0.1	2	23	1309	1330	1308	1330	0.95
23	26	0.00083	0.084	14.0	3.0	1	23	1336	1358	1336	1358	0.99
24	26	2.4e-06	0.00024	22.0	2.0	1	23	1364	1386	1364	1386	0.97
25	26	6e-08	6.1e-06	27.0	2.4	1	23	1392	1414	1392	1414	0.99
26	26	0.001	0.1	13.7	0.2	1	21	1420	1440	1420	1444	0.91

Sequence Information

Coding Sequence: ATGTTTCCGACCGATATTTGCCGCACATGTGCTCTACATGATGTACATTTGTTAGCGCTCTCAACGTGCACCGAGAAATATGCAAACAAAAGCTTCTACGACATGTTGCATGAACTGACACAAAACGATCCCTTAATGGAACATTCAGACGATAATCTGCCCCAGTATTTGTGTGGCGACTGCTTGCGTAAGCTGGAAGAGGCCTATGCATTCGTGTTGCAAGCACGTCAGGTGCAGGAGCAACTGTTGCACAAATTAAGCAAAGGCCTGCAGTGCCTGGATGAGACACCCATAGACATAGCCCCAGAGCACATAaagacagaaacagaaacagacatGGCCTTGGAGCCAACCAATGACAAAGTGGCAACTGTGGCTGTTGCAGCTTTAAAGATGCAGCCGGAAAGTGAGACCGACAGTAGCCCGTCAGATGCGGCTGACGATGATGTGCTAGACTTTAGACATTCACAGCTGAGACGCAGCACTCGGAAGACAAAACTTGGAACAGACAGCGAAAATGATGCAGATTGTGAAAAGCCAAGTGCAATGCCGCCCAAGCGTCGTCGTGGTCGTCCTGCACGTATTCTCAAAAAGGACACTATCAACAAGGACGGACGCCACGCGTGCGAGGTGTGCGGCAAGACGTTTTCGTGGCATCGCGACATGCAACGCCACGCTCGCGTCCACTTCGAGCAGGCTGGCTATGTGTGCGACAGCTGTGGCAAGGGATTTCTCCGCAAGGACAAGTACATGTTCCATTTGCGCTCGCACGAGAAGCGCCAAGCCAAACGGCAGGCCCTCCAGCTGGGTGGCGAGTGGCGCTTTGCGGAACGTCTGTACAGCTCGGGACGCCTCAAGCGTGTGGAGTGCAAGCTGTGCGGATTGAAATGTCAGCGGATTCCGGAACTTCGTGAGCATCTGACCAGTCATGTTAGCATTGAAACATTGTCGAATCTCAGCGCCGATAGCGATGTTATCGTGGAACAGTTTAACGGCCAGCGGCTAGACTTGATGCAGATTAAGCAACAAGTGTGTGCGGACATAGCCAAGGGAAGAGATCACTTGGATAAATACTGTGTGGTGGTCAATGCACATGGCTATGAACTTTGTCTGAGCGACTCGGACGAGGAATTGCCAGGAATGCCGCCTCCATACCAATGCCTGCCTTGCAACACACTCTTCTCGCGCAAACATCGCCTGATGCGGCACACGCTTGAGGAGCACACTCACCCGACAACTGAGGCAACTCCCTGGCAACGTTGCAACCAGTGCCAAATTGGCTTTGTGTGCGTTAAGCTGCTGGAACAGCATCAGCGCACACAGTGTCACAATCAAATGAAACGTTATAGTTGTCCCAACTGTCCAGGCAAATTTATATGGCGGCAGAACCTAAAGCATCATGCGTGCTCCCAACGCATGACAAGTTCAGAGGCACAGGATCGGGAGAGAAGTCAATCCCGCCGGATTCAGTGCTGTCTTTGCGATGAGCAACTGCAAAGTATGTCAGCACTACGCGTTCACCTATTAACACATTGCGATGGACAAAACGGCATTGATGCTGATCGACGTTCCACCTTCTTTAGTTGTAACTATCCCGGTGGTTCCACCTGCAACCAGACCGAGCTCAGCACACAAATTGTGAGGGATTTTGGGGCAGAGGATTACGGTCGCTACTTCAATGCCTGCACAGGCAGCGGTCAGGAGCTGGATTTCTTTGACTCTGATACGGATTTAAGCGATCAGTCAGCCGCAGCTGTCCACACGTGTGATTTGTGTGGTGTGAGCACTAAACGCCTTGCCCAACTCTTGAAGCATCAACAGATTCTTCACAGTGAGGTGGATGACACATTGCCCCACGTGTGCGACAAGTGTGAATTGGGATTTGTGACTGAATCGCTGCTTCGGCAGCATCGTCGACGCATTTGTGCAAAGCGACATGCAAAGTACCACTGTCAGCAGTGCAATCTCCATTTCATCTGGCAGTCCAACTACGAGCGACACATGGAACTGCAGCACGAGGCCGAGGCAGAGGCAGGTGATGCCCCTGATAGTGTGCCCAATACCAGGCTAAGAAGCAAACGCCAACAAGCTGCCAAACTGCAGTGCAATGAATGCGAAAAGgTCTTCATCTGGCCGAAGGATTTGACGCGTCACAAGCGCATTCATCAGCCGCAGGCATCGGCACAGTACGAATGCAGCTACTGTGAGCGCAAGTTCCATCGCAAGGATGGCCTCAAGTCCCACATGCGTGTCCATGGCGAGCAGCATTTGGATGTGACGGTTGTGCCTAACAGTGATCCGGATCCGACGACATTACAGCGAATGCCAATGGTGTTGACGCAATTGTGCCAACCGAATGGATGCAAGCTGATTCAGTGCATGATCTGTCTGTCTAGGCACACGAAGATCTCTGATCTGCGCATGCATTTGGTGAAGCATCGGTTTGCTGTGGAATTTGCGGAGGATCGTGCCAAGCCGGAGGGCATAGAGAGTATTTGCCGCGCTCTGTATCCGGAGCAGGTGACTCTGCTGGATGAGCAACAATTAATTGAACGCATCCAGATGGATGTGGGCATGGGAACTGAGTTGGAAAGATTCATTTCAATAACAAACGAGGCAGGCATAGAGCTTAGCCTGGACAGCAGCGAAACTGAAACGGATTCGGACTCGGCCGAAGTGGAAAGGAACAGCAGTGAACGACAATACTGCTGTGATCTTTGCCAGCTGAACTGGCCACGTAAACATCAACTCTATGCCCACCAGCTGGAGCAGCATACATGGGAACAGGCAACACACGTTTGTACCCATTGTCAGGCCAGATTCATCAACGACCAGTTGTTGGATCACCACTATCGTAGTCTCTGTCGCAATGTCCACAAGCGTTTTCTCTGTCGAAAATGTCCCTTAAGGTTTCGCTGGCGCGACAATCTGAAGCTGCACATGGACGTGTCGCATCAGGAAACAACTGGAGAACAGACAAACTTGGGCCTCCAATTGAGTGGGGCAAGTGTCCTTCCCGTTGTCAGCTACGACTGCACCGAATGCAATCGCAgcttcaaaatgcaaaaggatCTTACAAGGCACACACTGATGCATGCCCAGGAATCCAGCATTTACCGGTGTCGTTGGTGTGCCCGTCGCTTCTATCGCCAGGCCAATCTCCTGCAGCACATTGAGCGTCATGGAATTAATGCCGCGCAGCTGCCCTATGCCGAGTCCCTGCTCAATGCCAGCCGTCATCCCCATGGCACGAAGTGCATCCAATGCAAGGTGTGTGATATTCATTTTTCCACAATTGCCGCACTACGTTCCCATTTGGCGTCCGCGCCGAGCGGGACTCATCATGAAATTGGATCGATGCTCAACTACTCGATTACCAATCAGCTGGGCTATGAGCTGCACCTGGAGGACTCGGAAACGGATGAGGAGGCCAAGCCGCCTGGCATACCCAGCCACTACACGTGCGGCATGTGCCAGCTGCGTTGTGTCCGCAAATATGAGctgcatcagcatcagcaggcCATGCATCGATTGGAACGGATCACGGAGGGCTGTGATCAGTGTATCTATAAGAGCGTTTCCCCACATCTTATCGCCTATCATCGGCGTGTGCAATGTTGCAACACGGAGAAGCAATTCAAGTGCGTCAACTGCGATTACAAGTTTATGTGGGAATCGAATCTGCTGCTCCACATTCAATTGCAGCATCCTGGCAAAGATGAGACAGTATCAGTGCCTGATCCAGAGACAGCTACTGTGGAGTCCCAGATCTTCCAGTGTGGTCAATGCCCGCGTAGATACAATCGCAAGGATCGACTGACGGCCCATGTAAAGAAGTGTCATGCACCTGGCGCAGTCGGTCCAACTGTCTCTCCAACAAAAACATCAACGTCTTCAAGTGTCGCCAAACAACAGAAAAGTTTTCTCTGCGCCTTTTGTGGCAAGGCGGTGAGCTCCTCCTCCAATCTCATTATACACATACGTCGTCATACCGGCGAGAAGCCCTTCAAGTGCGACTTCTGCGAGATGGCCTTCCCCCGCTCCTCCGATCTGCAGTGCCATCGACGCACTCACACTGGCGAACGGCCACATGTCTGCACCGTCTGCCAAAAGGGATTCGCTCGCTCCTACAAGCTCCAGCAGCATATGCGCATCCATAACGGCGAACGTCCCTACAAGTGTACCTACTGCGACAAGAGCTTCACACAGTCCAATGATCTCACGCTCCACATACGACGACACACGGGCGAGCGACCCTATCAATGTGACACCTGCGGGGAACGCTTCATCCAGGGCACAGCACTCAAGAATCATCGGCTACAGAATGGCCATTTCGGGACGGGGGATAGCCTAGCAAAAACTAATTAA
Protein Sequence: MFPTDICRTCALHDVHLLALSTCTEKYANKSFYDMLHELTQNDPLMEHSDDNLPQYLCGDCLRKLEEAYAFVLQARQVQEQLLHKLSKGLQCLDETPIDIAPEHIKTETETDMALEPTNDKVATVAVAALKMQPESETDSSPSDAADDDVLDFRHSQLRRSTRKTKLGTDSENDADCEKPSAMPPKRRRGRPARILKKDTINKDGRHACEVCGKTFSWHRDMQRHARVHFEQAGYVCDSCGKGFLRKDKYMFHLRSHEKRQAKRQALQLGGEWRFAERLYSSGRLKRVECKLCGLKCQRIPELREHLTSHVSIETLSNLSADSDVIVEQFNGQRLDLMQIKQQVCADIAKGRDHLDKYCVVVNAHGYELCLSDSDEELPGMPPPYQCLPCNTLFSRKHRLMRHTLEEHTHPTTEATPWQRCNQCQIGFVCVKLLEQHQRTQCHNQMKRYSCPNCPGKFIWRQNLKHHACSQRMTSSEAQDRERSQSRRIQCCLCDEQLQSMSALRVHLLTHCDGQNGIDADRRSTFFSCNYPGGSTCNQTELSTQIVRDFGAEDYGRYFNACTGSGQELDFFDSDTDLSDQSAAAVHTCDLCGVSTKRLAQLLKHQQILHSEVDDTLPHVCDKCELGFVTESLLRQHRRRICAKRHAKYHCQQCNLHFIWQSNYERHMELQHEAEAEAGDAPDSVPNTRLRSKRQQAAKLQCNECEKVFIWPKDLTRHKRIHQPQASAQYECSYCERKFHRKDGLKSHMRVHGEQHLDVTVVPNSDPDPTTLQRMPMVLTQLCQPNGCKLIQCMICLSRHTKISDLRMHLVKHRFAVEFAEDRAKPEGIESICRALYPEQVTLLDEQQLIERIQMDVGMGTELERFISITNEAGIELSLDSSETETDSDSAEVERNSSERQYCCDLCQLNWPRKHQLYAHQLEQHTWEQATHVCTHCQARFINDQLLDHHYRSLCRNVHKRFLCRKCPLRFRWRDNLKLHMDVSHQETTGEQTNLGLQLSGASVLPVVSYDCTECNRSFKMQKDLTRHTLMHAQESSIYRCRWCARRFYRQANLLQHIERHGINAAQLPYAESLLNASRHPHGTKCIQCKVCDIHFSTIAALRSHLASAPSGTHHEIGSMLNYSITNQLGYELHLEDSETDEEAKPPGIPSHYTCGMCQLRCVRKYELHQHQQAMHRLERITEGCDQCIYKSVSPHLIAYHRRVQCCNTEKQFKCVNCDYKFMWESNLLLHIQLQHPGKDETVSVPDPETATVESQIFQCGQCPRRYNRKDRLTAHVKKCHAPGAVGPTVSPTKTSTSSSVAKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDFCEMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCDTCGERFIQGTALKNHRLQNGHFGTGDSLAKTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00558059;
90% Identity: iTF_00601963;
80% Identity: -