Dsub002409.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila subobscura
Gene Symbol
ftz-f1
Assembly
GCA_008121235.1
Location
NC:2657339-2701840[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 2 1.3e+04 -6.5 8.0 71 147 34 148 10 170 0.40
2 4 2 1.3e+04 -14.3 17.0 115 129 303 317 132 375 0.50
3 4 1.8e-19 1.2e-15 57.5 0.4 1 76 566 640 566 666 0.79
4 4 1.4e-70 8.9e-67 225.8 2.1 157 408 772 1016 752 1018 0.92

Sequence Information

Coding Sequence
ATGGACACCTTCAATGTACCTTTGCTGGCGgagagcaccagcagcagcagcaattatGCGATAGCAGCAGTCACAGaggcaacaaacagcaacaaccatcatcatcatctgcagcaccagcaaaatCTTATGTCCCACCATCACAAGGATCAGATGCTGGCGGCGGGAAGTAGTCCCATGCTGCCATTCCTCAGTTActctcagctgcagctgcagcagaaggatACTACtgctaccagcagcagcaatggtgCACAATCAGCATCcgaaggagcagaagcagcagcagcagcaattgccaCAGATAATTTTGATGGCAGCCAATTGGATGGTGGCATCTCTCTGAGCGGCCTCTGCGAACGCTTCTTTGTAGCCAGTCCCAATTCTCATAGCAATAGCAACATGACCCTAATGGGCGCCCCCAAtccaacaaccacaacagctAGCCAGCACAACActaacatcaacaacaacaacaatttggagGCTAAAAACGGGACCAGCCTCACAGGTGCGGGAGCTCCCCAATCGCTGCAGAGAGGCGGAGGATCAGTTATCATCGAATCGGTGACCGTGCCTTCTTTTGCCAACATCCTCTTCTCCCATCGAAATTCTCAAGCCACATCGAATGAATGCATCGATCCGGCACTGCTGCAGAAGTCCTCACTATCCAGCAGCTCCATTATAGAGTACCATCAGCTGAAACCCCTGGCACCGAGTGCCACCAACTCGGCGTCCGTTTCCACCAGCAATTTCCTGTCCTCGAGCACCGCTCAGCTGTTGGATTTTGATGTGCAAGGCACTTCCAAGGATGAAAGCCATATAAGtaccaccacaaccacagctGGAGTGGGAATAGGTGCAGGATCGGGTTCGAGTTCAGGATCCGCATCGGGTGTACAATCAACAACAATCAGTGCCAATCAGACAAGAAGCTCGCTGCACAGCATCGAGGAATTAGCTGCCAGCTCCTGTGTTGCACCCAAAACCACCCAATCACCCAATgggaacgagaacgagaaccaCAGGACTACCACTAGTACAACGCatcagcaggaacagcagcaacagcatcccaTACAACAAAGTGGCAATCACAGTGGATCCAATCTCAGCTCTGATGATGAGTCCGTTTCAGAGGATGAGTTCGGTCTGGAAATCGATGATCACGGAGGCTACCAGGACACCACCTCCTCCCACTCACAGCAGAGTGGCGGTGggggcggaggcggtggcggagcTGGCAGCAACATCCTCAACGGCAGCTCGGGCAGCAGCTCTGGCtacatgctgctgccccaagcggccagctccagcggcaACACCAATGCCGCCCACATGTCCTCCGCCGCCGGATCCGTTGGCACTGCCAGCGGCCCCAACGGTGGTGGAGGCGGTCCCGGCCCGGGCAATGCCATGGGCGGTACGAGCGCCACACCGGGACACGGCGGTGAAGTGATCGACTTCAAGCATCTCTTCGAAGAGCTGTGTCCCGTATGCGGCGACAAGGTCAGTGGCTACCACTACGGCCTGCTCACCTGCGAGTCATGCAAGGGCTTCTTCAAGCGGACTGTCCAGAACAAGAAGGTCTACACCTGCGTGGCGGAGCGGTCGTGCCACATCGACAAGACGCAACGCAAGCGGTGTCCCTACTGCCGTTTCCAAAAGTGCCTGGAGGTGGGGATGAAGCTGGAGGCTGTACGAGCGGATCGGATGCGGGGTGGCAGGAACAAGTTCGGACCCATGTACAAGCGAGATCGGGCGCGGAAGCTGCAGGTCATGCGCCAACGGCAGATCGCCCTCCAGGCTCTGCGCAACTCGATGGGGCCGGACATCAAGCCGACGCCGATCTCGCCGGGCTACCAAGCATATCCAAATATGAACATTAAGCAGGAAATCCAAATACCTCAGGTATCCTCACTCACGCAATCGCCAGACTCGTCGCCCAgccccattgccattgctctGGGCCAGGTGAATGCCAGCACGGGCGGAGTGATATCCACGCCCATTAATGCCGGAAACGGGGGCAGTGGCGGTCTGAACGGCCCCAGCTCCGTTGGAAATGGCAatagcagcaacggcagcagcacaggcaacaacaacaccggcagcagcacaggcaaCGGTGCAGTTGGCGCcggcggaggaggcggtggaggcaacaatgcgggaggcggcggcggcaataACAGTTCCACCGACGGCCTGCAtcgcaacggcagcggcaacggcagctgccACGAAGCTGGAATAGGATCTCAGCAGAACTCGGCCGACTCGAAACTGTGcttcgATTCCGGCACTCATCCATCGAGCACAGCCGATGCGCTTATCGAGCCACTGAGAGTCTCCCCGATGATACGAGAATTTGTGCAATCGATTGACGATCGGGAATGGCAGACGCAGCTGTTCGcgctgctgcagaagcagacCTACAACCAGGTGGAGGTGGATCTCTTTGAGCTGATGTGCAAGGTGCTCGATCAGAATCTGTTCTCGCAAGTGGACTGGGCAAGGAACACGGTCTTCTTTAAGGACCTGAAGGTCGATGATCAAatgaagctgctgcaacaCTCCTGGTCGGACATGCTGGTTCTCGACCATCTGCACCATCGGATCCACAACGGGCTGCCCGATGAGACGCAGCTAAACAATGGCCAGGTCTTCAATCTTCTCAGTCTGGGGCTGTTGGGCGTGCCGCAATTGTCCGACTATTTCAACGAGCTGCAGAATAAGCTGCAGGACCTGAAATTCGACATGGGCGACTATGTCTGCATGAAATTCCTTATACTTTTGAATCCAACTGTACGAGGCATTGTGAACAGAAAGACCGTGTCAGAGGGACATGATAATGTGCAGGCAGCCCTTCTGGACTACACCCTCACCTGTTATCCTTCAGTCAATGACAAATTCAGTAGGCTAGTGAACATCTTACCGGAAATCCATGCCATGGCCGCACGCGGCGAGGAGCACCTCTACTCCAAACACTGTGACGGCAATGCACCCACCCAGACTCTGCTCATGGAGATGCTGCACGCCAAGCGGAAGGTGTAG
Protein Sequence
MDTFNVPLLAESTSSSSNYAIAAVTEATNSNNHHHHLQHQQNLMSHHHKDQMLAAGSSPMLPFLSYSQLQLQQKDTTATSSSNGAQSASEGAEAAAAAIATDNFDGSQLDGGISLSGLCERFFVASPNSHSNSNMTLMGAPNPTTTTASQHNTNINNNNNLEAKNGTSLTGAGAPQSLQRGGGSVIIESVTVPSFANILFSHRNSQATSNECIDPALLQKSSLSSSSIIEYHQLKPLAPSATNSASVSTSNFLSSSTAQLLDFDVQGTSKDESHISTTTTTAGVGIGAGSGSSSGSASGVQSTTISANQTRSSLHSIEELAASSCVAPKTTQSPNGNENENHRTTTSTTHQQEQQQQHPIQQSGNHSGSNLSSDDESVSEDEFGLEIDDHGGYQDTTSSHSQQSGGGGGGGGGAGSNILNGSSGSSSGYMLLPQAASSSGNTNAAHMSSAAGSVGTASGPNGGGGGPGPGNAMGGTSATPGHGGEVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQIALQALRNSMGPDIKPTPISPGYQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVISTPINAGNGGSGGLNGPSSVGNGNSSNGSSTGNNNTGSSTGNGAVGAGGGGGGGNNAGGGGGNNSSTDGLHRNGSGNGSCHEAGIGSQQNSADSKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLLSLGLLGVPQLSDYFNELQNKLQDLKFDMGDYVCMKFLILLNPTVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFSRLVNILPEIHAMAARGEEHLYSKHCDGNAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00514941;
90% Identity
iTF_00563935;
80% Identity
iTF_00601106;