Basic Information

Insect: Drosophila sturtevanti
Gene Symbol: ush
Assembly: GCA_018150375.1
Location: JAECWJ010000335.1:889959-895750[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0061 0.43 11.1 0.0 1 20 214 233 214 235 0.90

2 9 0.00026 0.018 15.4 0.8 1 23 288 310 288 310 0.98

3 9 0.047 3.3 8.3 1.0 2 21 351 370 351 371 0.92

4 9 0.045 3.2 8.3 2.9 2 21 694 713 693 714 0.93

5 9 0.0084 0.59 10.6 0.0 3 21 776 794 774 795 0.91

6 9 0.025 1.7 9.1 0.0 2 23 861 882 860 882 0.98

7 9 0.0036 0.25 11.8 1.3 1 23 888 910 888 910 0.99

8 9 0.00063 0.044 14.2 0.8 1 23 972 995 972 995 0.96

9 9 0.35 25 5.5 0.4 2 19 1117 1134 1116 1136 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0061	0.43	11.1	0.0	1	20	214	233	214	235	0.90
2	9	0.00026	0.018	15.4	0.8	1	23	288	310	288	310	0.98
3	9	0.047	3.3	8.3	1.0	2	21	351	370	351	371	0.92
4	9	0.045	3.2	8.3	2.9	2	21	694	713	693	714	0.93
5	9	0.0084	0.59	10.6	0.0	3	21	776	794	774	795	0.91
6	9	0.025	1.7	9.1	0.0	2	23	861	882	860	882	0.98
7	9	0.0036	0.25	11.8	1.3	1	23	888	910	888	910	0.99
8	9	0.00063	0.044	14.2	0.8	1	23	972	995	972	995	0.96
9	9	0.35	25	5.5	0.4	2	19	1117	1134	1116	1136	0.91

Sequence Information

Coding Sequence: ATGGTTAGACAGCAACAACAACAACAACAGCAACAACAACAACAAGCTGCCGCCGCCACTGGCAAGCGATCGTTCGGTCGCATTGTCGCATTGTTTTCACAGCTCTTCTTAAAGTGGAATGGCGATCAGGCAACAGAAGCTGAAGAGGAGACAAATTCTTTAGAAGAATCTTTAGAAGAATTGCAGGAAATAAATCGAATACAGGGAAAGCAGCGAGAAGCAAAAGAAGAAGAAGAAGAAGATGATGATGAAACAATGGCCACAACTCCACCACGTAGTCCATTAGCCGAGGCGGTCGATAATGCCGATTCAACCGGAATCAATATAGTTGATGGCATAGTGCCAAAACTGGAGGAACCGGCGACACCGCCAACACCTCCATCGCCCTGCCCCTCACCAATAAGTCAATCGCCCACTCTTCCATCACCACCACCAGCCCCGCTGCCACCACCAGGAACGCTGCCCAAATTGCGTTTAAATGCTTTGCTAGCTTCCGATCCTGCACTGAAACCGGATGCTAAGGAGCTTAATCTTTTAGGACCACCTTCTATGAATAAATCCGTAACATCACTACCACCACCACAACCACAACCCACTGAGCAGCCCGAGTTGGTAGAGCCCTTGCTGAAACCAGCGAGATTCATGTGTCTACCATGTGGGATAGCCTTCAGTTCGCCCTCAACACTGGAGGCGCATCAGGCTTATTATTGTTCACACCGGCCTAAGGAGACACCCGAACAGGATGAAGTCGGTGGAGACAAGGGAAACGATGGATCAATCAACTCAAATGCAGCAAGCGGTGGCAACGGTACCGGATCCACCAACGAACCACCAGCAAAAGTGTCACGAATGGGTAAGCAATATGCCTGCACACAGTGTTCCTACAGTGCAGACAAAAAAGTATCTCTAAATCGGCACATGCGAATGCATCAATCCTCGCCAGCAACAACCACAACAACAGCGGTGGTATCCATCACACCCAATGGCGTAGGATTGGGAATAAATCCCCTACAAGAGGAGACCTCTAGTCAACATCAGCAAATCGATCGTTACTGCAGCGACTGTGATATCCGTTTTAATAATATCAAAACGTATCGCGCCCATAAGCAACATTATTGCAGTTCCCGTCGATCGGATGGCCAATTGACACCCAAACCGGAAAGCCAAACTGGTCCAGGTGTGGGAGGTGGAGGAGGAGGAGGAGCAACTGTCGCAACACTTGGTGGAGCCAGTGGCGCTCTAAGTCCGCAAACCAATCGTAATCATGCCAATAAGACTCCAACACCGGCTATGGTAGCAGCTGCAGCTGCTGCTGCTGCTGCAGCGGCCGCTTCATTGCCACCTCCTCATCAACCATTTTTGGCACTGCCCACCAATCCAATCATCATAGTGCCCTGCTCACTGATAAGAGCGGCCAGTCTCATACCAGGACCACTCACCACTGCCACCTCAGGCATAGTTAATCCGGAATCCACCTGTTTTACGCTTGATAATGGAGCACTCAAACCGCTAGCAACGGCCTTAAATATGGCCAATCCATTGCTGGATACAGCCAAGGAAGCGTCATCATCCTCCATCACATCGGAACAGCCGGCAGCACCAGCAGCAGCAGCTAAGCCAAGGAGCAGTCCCTCTGAGGGAATCAAACGCAAAGGAAGCCACGGGCATGAAACGGTTCCATTGGATCTTTCACTTTCGCGTCGTTCACCTATCTCAGCTTTGCTTCAGCGTCAGGATCTATTAATGGCTGGTCTAGGTCTCAGTTTGGGTTTGGGCAAAGAGAATCTCTTAATGAATGAGAATCATCGGGTGTTGACACCCGAACAGATTCAACAACATTTGTTGGACAACTTGCCTCCTCTACGTTCCATGTTGCCAGCGGAATTCGCCTTAACCGAATCTCTGCTGGCCAAAACAAATCCGGAATTGGCATTAAAATTGGCTGCCGAATTGGCTAACAAATTGGCAGCTGGTTTTACAGGATCAGTGCCCACAGCACCGCCTCCAACATCAGCACCCACAACACCTGTCGCCAGTTCTGCCAATCAGCCACAGATCTATGTGAAACAAGGTGTATCCAAGTGCAAAGAGTGCAACATTGTCTTCTGTAAATATGAGAATTATTTGGCCCACAAACAACATTATTGCTCGGCACGTAATCAGGAGACAAGCGGAGGAGGATCAGGCAATGGCGGCGGCGGCGGCGCTGAAGTCGAGAATTCCAATTTGAAATCTTCACCGCCACCAGCGGGTACGGGGGGTGGAGGTGCCGGTAAAGTTGCATCATCTGAATCTACACCTGCTGTGGCCTATCAACAATTAATTTGCGCTGCATGTGGCATTAAGTACACATCCCTGGATAATTTACGAGCACATCAAAACTATTATTGCCCGAAAGGAGCCAATGCAGCACCTCCTGCAACAGCAGCGGTAACTGCACCGCCACCCACAACGGATGATCGCCTGTTAATGGTGAAGGAAAAGTGTATAAAATGCAAGAGTTTACATGATCCAAGTCAATCCTGTCCAGCAAGTGTAGTTGCAGCGGGAGCCACAACTAGTTCCACCAATAGTGTCAATAAATGTCCCGTTTGTGGTGTGATCAGTCCCAGTGCTGCTCTCGCCCGCAAGCATATGGAAATGCATGGAACAGTTAAGGCATTTCGCTGCAGCATTTGCCAATACAAGGGCAACACCTTACGTGGCATGCGCACCCATATACGCACCCATTTCGATAAAAAGACGAGCGATGTCAACGAGGAGCACTACATGACCTGCATTTTTGAAGAGGAGACTGCAGTCCTATCATCAGCAGGCGGAGTAGGAGTAGGAGTTGGTGTAGCGGCAGGTGGAGTCGAAATACCAGCAGCAGCCGCAGATCAGCAACTTTTAGATCAGCATCCTCCACAGATTTTCAATTGTGAATACTGCAACTATGCCTCCACCTACAAGGGCAATGTGCTGCGTCACATGAAGCTCTTGCATCCCCATGTGGCCATCTTAAACTCACCATCGATATCGCCCGAATCACGAGATCAGCAACAACAGGACATTCTTTCGAATACGCAAGTCCTATCCGATGTCGCAAACGGAGAAGGAACCAGTTTTCACATAAAATCAGAGCCCATGGATCATGTAATAGCACCACCTACACCAAATCTACCGCCACCAGCACCCACCTTAGGTCTAATGCATGAGAACAATAACTCACCCATTACTACGACCCACATAAAACCTGAACCTGGTCTGGATATTGATGTCTCGCCACCAAGTTCCATGAGTTTGGCTAGTGGTGGACCTGTGCCATCGCCTGTTTTGACAGCCGCTGCAGCAGAGGCCATGAAGAAATACTGTTCCACCTGCGATATATCCTTTAATTATGTAAAAACTTTTTTGGCCCATAAGGAATTCTATTGTAAAAGTAAACAACAGCGACCCGAGGCCAGCGATTGCCCCAGCCCCAATCAGATGACGGGGGGTGGTACCGCAGCTGCTGGCGGAATTGGCGGCTTGTTAGGAATGGGAGGTGGTGGTGGAGTCCAGCCATTGCAATCTCCCAACGAATTGATAATGTTGCAAAAGAATAAGGAGAATCTGCAAGAGGCGGCCATTTGA
Protein Sequence: MVRQQQQQQQQQQQQAAAATGKRSFGRIVALFSQLFLKWNGDQATEAEEETNSLEESLEELQEINRIQGKQREAKEEEEEDDDETMATTPPRSPLAEAVDNADSTGINIVDGIVPKLEEPATPPTPPSPCPSPISQSPTLPSPPPAPLPPPGTLPKLRLNALLASDPALKPDAKELNLLGPPSMNKSVTSLPPPQPQPTEQPELVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRPKETPEQDEVGGDKGNDGSINSNAASGGNGTGSTNEPPAKVSRMGKQYACTQCSYSADKKVSLNRHMRMHQSSPATTTTTAVVSITPNGVGLGINPLQEETSSQHQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPESQTGPGVGGGGGGGATVATLGGASGALSPQTNRNHANKTPTPAMVAAAAAAAAAAAASLPPPHQPFLALPTNPIIIVPCSLIRAASLIPGPLTTATSGIVNPESTCFTLDNGALKPLATALNMANPLLDTAKEASSSSITSEQPAAPAAAAKPRSSPSEGIKRKGSHGHETVPLDLSLSRRSPISALLQRQDLLMAGLGLSLGLGKENLLMNENHRVLTPEQIQQHLLDNLPPLRSMLPAEFALTESLLAKTNPELALKLAAELANKLAAGFTGSVPTAPPPTSAPTTPVASSANQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQETSGGGSGNGGGGGAEVENSNLKSSPPPAGTGGGGAGKVASSESTPAVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGANAAPPATAAVTAPPPTTDDRLLMVKEKCIKCKSLHDPSQSCPASVVAAGATTSSTNSVNKCPVCGVISPSAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEETAVLSSAGGVGVGVGVAAGGVEIPAAAADQQLLDQHPPQIFNCEYCNYASTYKGNVLRHMKLLHPHVAILNSPSISPESRDQQQQDILSNTQVLSDVANGEGTSFHIKSEPMDHVIAPPTPNLPPPAPTLGLMHENNNSPITTTHIKPEPGLDIDVSPPSSMSLASGGPVPSPVLTAAAAEAMKKYCSTCDISFNYVKTFLAHKEFYCKSKQQRPEASDCPSPNQMTGGGTAAAGGIGGLLGMGGGGGVQPLQSPNELIMLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00501345; iTF_00483983; iTF_00591239; iTF_00578060; iTF_00556091;
90% Identity: -
80% Identity: -