Basic Information

Insect: Drosophila austrosaltans
Gene Symbol: ush
Assembly: GCA_035045865.1
Location: JAWNOQ010000135.1:1590045-1608118[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.007 0.79 11.0 0.0 1 20 224 243 224 245 0.90

2 9 0.0003 0.034 15.3 0.8 1 23 297 319 297 319 0.98

3 9 0.054 6 8.2 1.0 2 21 360 379 360 380 0.92

4 9 0.052 5.8 8.3 2.9 2 21 747 766 746 767 0.93

5 9 0.0096 1.1 10.6 0.0 3 21 826 844 824 845 0.91

6 9 0.0099 1.1 10.5 0.0 2 23 911 932 910 932 0.98

7 9 0.0041 0.46 11.7 1.3 1 23 938 960 938 960 0.99

8 9 0.00054 0.06 14.5 0.7 1 23 1020 1043 1020 1043 0.96

9 9 0.32 36 5.8 0.7 2 20 1161 1179 1160 1181 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.007	0.79	11.0	0.0	1	20	224	243	224	245	0.90
2	9	0.0003	0.034	15.3	0.8	1	23	297	319	297	319	0.98
3	9	0.054	6	8.2	1.0	2	21	360	379	360	380	0.92
4	9	0.052	5.8	8.3	2.9	2	21	747	766	746	767	0.93
5	9	0.0096	1.1	10.6	0.0	3	21	826	844	824	845	0.91
6	9	0.0099	1.1	10.5	0.0	2	23	911	932	910	932	0.98
7	9	0.0041	0.46	11.7	1.3	1	23	938	960	938	960	0.99
8	9	0.00054	0.06	14.5	0.7	1	23	1020	1043	1020	1043	0.96
9	9	0.32	36	5.8	0.7	2	20	1161	1179	1160	1181	0.91

Sequence Information

Coding Sequence: ATGCTTAGCAGTTGCACTAAAGGTGATTGTTCCGATACCACAGAAGAAATGACTGTCGACAGTAGAGAATCCAAAGATTTAGCCGATCACGAGTTGGGTGAGGAGCAACAGTTTGATGACCAAacttccaacaacaacaacaataataataatagtaatgcTAGCGATCAGTTACAAGAAGCGGAAGAGGAGACAAATTCCTTAGAAGAGTCCTTAGAAGAATTGGAGGAAATAAATCGAATACAGGGAAAGCAGCAAGATGcgaaagaagaaggagatgaGGAAACAATGGCCACAACGCCACCACGTAGTCCATTAGCCGAGGCAGACGATAGTGCTGAGGCAACTGGAATTAATGTAGTCGATGGCATAGTGCCCAAATTGGAAGAACCGGCCACACCACCAACACCTCCTTCACCCTGCCCCTCACCAATAAGTCATTCGCCCATACTTCCATCGCCTCCACctccgccgccaccaccagtAACGCTGCCCAAATTACGTTTAAATGCTTTGCTTGCCTCCGATCCTGCACTGAAACCGGATGCCAAGGAGCTCAATCTGCTAGGTCCACCGGCTATGACTAAACCAGCACCATCACTACCACCACCACAGCCACAGCCGACGGAACAGCCCGAGCTGGTGGAGCCCTTGCTAAAGCCAGCGAGGTTCATGTGTCTGCCATGTGGCATAGCCTTCAGTTCACCCTCAACACTGGAGGCGCATCAGGCCTATTATTGTTCACACCGACCCAAGGAAACGCCCGAACAGGATGACGCCGGAGGGGAGAAGGGAAACGATGGATCAATCTCAAATGCAGCCAGCGGTGGCAGTAGTAGCGGATCCTCAAATGAACCGCCAGCCAAAGTGGCACGAATGGGTAAGCAATATGCCTGCACTCAGTGTTCCTACAGTGCGGATAAGAAGGTATCTCTCAATCGGCACATGCGAATGCATCAATCCTCGccagcaacaaccacaaccaCAGCGGTGGCATCCATTACAGCCAATGGCGTGGGATTGGGTATTAATCCCCTACAAGAGGAGACCTCTAGTCAAcatcagcaaatTGATCGCTATTGCAGCGACTGTGATATCCGTTTCAATAATATCAAAACGTATCGAGCCCATAAGCAACATTATTGCAGTTCCCGGCGATCGGATGGACAATTGACACCTAAACCGGAAAACCAAGCTGGTCCTGGTGGTGGGGGTGGAGGAACTGTTGCAACTGCTGGTGGAGCCAGCGGTGCCCTAAGTCCGCAAACCAATCGCAATCATGCCAATAAGACCCCAACTCCAGCTATGGTGGCAgctgcggctgctgcagctgctgcggCGGCTGCCGCTTCATTGCCACCGCCACCTCAACCCTTTCTGGCACTGCCCACCAATCCAATCATCATTGTGCCCTGTTCATTGATAAGAGCGGCCAGTCTTATACCAGGACCACTCACCACTGCCACCTCAGGCATAGTTAATCCGGAATCCACCTGCTTTACTCTTGACAATGGAGCACTCAAACCGCTGGCAACGGCTTTAAATATGGCTAATCCTTTGCTGGATACAGCAAAGGAAACATCCTCATCATCCATTACAACGGAACagctggcagcagcagcatctaaGCCAAGGAGTAGTCCCTCCGAGGGTATTAAACGCAAAGAAGCCACTGGTAACCGTGAAACGGTACCATTGGATCTCTCATTGTCACGTCGTTCCCCCATCTCAGCTTTGCTGCAACGCCAGGATCTATTAATGGCTAATCTAGGTCTTAGTTTGGGTTTGGGCAAAGAGAATCTCCTAATGAATGAGAATCATCGAGTGGTCACCCCAGAACAGATTGTGTGTGCCCCATCATTGCCCAGCAGTCCATCGATGAGTCCCTCGCCAAAACGTCGGGCTATGAGTCCAGCGCCAGGACGTAGCTCTTCGGGCGGTGGAAGTACAGCATCCATGTCGCCaccccagcaacaacaacagcaacagcagcagcatttatTGGACAATTTGCCTCCTTTACGTTCCATGTTGCCAGCGGAATTCGCCTTAACTGAATCTCTGTTGGCCAAAACTAATCCAGAATTGGCACTAAAGTTGGCCGCGGAGTTGGCTAACAAATTGGCCGCTGGTTTTACAGGATCAGTGCCGACAGCACCGGCGCCAGCATCGGCACCGACAACACCTGTCGCAGGATCCACCAATCAGCCGCAGATCTATGTGAAACAGGGTGTGTCCAAGTGCAAAGAGTGCAATATCGTCTTCTGTAAATATGAAAACTATTTGGCCCACAAGCAACATTATTGCTCAGCACGCAATCAGGAGGCAAGTGGAACTGGATCAGGAAGTGGCGGTGTTGAAGGGGATAATGCCAATTTGAAGTCTTCAACACCCCCACCTGGAACAGGAAGCGCAGGGGCCGGAGGAGTGCCATCATCCGAATCTTCTCCTGCTGTGGCCTATCAACAATTGATTTGTGCTGCCTGTGGCATCAAATACACATCCCTGGATAATCTACGAGCTCATCAAAATTACTACTGCCCCAAGGGAGCTAATGCGGCTCCGGCTGCAACTGCAGCGGTGTCAGCACAAGTTCCCTCCTCGGATGACCGCCTGCTCATGGTGAAGGAGAAGTGCCCGAAATGCAAAAGCTTACACGATCCAAATCAATCTTGTCCAGCAAATGTAGTTGCAGCTGGTATCCCAACCAGTTCCACCACTAGTGTTAATAAATGTCCTGTTTGTGGTGTGGTCAGTCCCAGCGCTGCTCTTGCTCGCAAGCACATGGAAATGCATGGAACTGTGAAAGCATTCCGCTGCAGCATTTGCCAATACAAGGGCAACACCTTGCGCGGCATGCGCACTCACATACGCACTCATTTCGATAAGAAGACCAGCGACGTCAACGAGGAGCACTACATGACCTGTATTTTTGAAGAGGAGGTAGCAGCcctagcagcagcaggaacTGGAGGAGGAGTAGCAGTAGGAAGTGGTGTGGATATACCAGCAGTAGCCACAGATCAGCAACTGTTAGATCAGCATCCTCCACAGATTTACAATTGCGAATATTGCAACTATGCCTCCACCTACAAGGGCAACGTGCTGCGTCACATGAAGCTATTGCATCCACATGTGGCTATCATAAATTCGCCATCAATATCGCCCGAATCACGagatcagcagcaacaggacATCCTCTCGAATACGCAAGATGTGGTCAACGGAGAAGGCGCCAGTTTCCACATTAAATCGGAGCCCATGGATCATGTAGTAGCACCATCTACACCAACTctaccgccaccaccacccacTTTAGGTCTAATGCATGAGAACAATAACTCGCCCATTGCCACGCCCCACATTAAAGCTGAGCCTGGCCTAGATATTGATGTTTCCCCACCCAGTTCCTTGGGTGTGGCCCCGCCACCTGTATCGTCTCCTGTTTTGACGGCCGCTGCAGCGGAGGCCATGAAGAAATACTGCTCCACCTGCGACATATCCTTTAATTatgtgaaaacttttttggCCCATAAGCAATTCTATTGCAAAAGTAAACCACACCGCCCCGAGGCTAGCGATAGCCCCAGTCCCAATCAGATGACTGGCAGCGGTGGCGCCGCTGCTGCAGGCGGAGTAGGTGGTTTGTTGGGAATGGGTGGCGCTGGTGGTGTCCAGCCGCTGCAATCACCTAGCGAATTGATGATGTTGCAAAAGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MLSSCTKGDCSDTTEEMTVDSRESKDLADHELGEEQQFDDQTSNNNNNNNNSNASDQLQEAEEETNSLEESLEELEEINRIQGKQQDAKEEGDEETMATTPPRSPLAEADDSAEATGINVVDGIVPKLEEPATPPTPPSPCPSPISHSPILPSPPPPPPPPVTLPKLRLNALLASDPALKPDAKELNLLGPPAMTKPAPSLPPPQPQPTEQPELVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRPKETPEQDDAGGEKGNDGSISNAASGGSSSGSSNEPPAKVARMGKQYACTQCSYSADKKVSLNRHMRMHQSSPATTTTTAVASITANGVGLGINPLQEETSSQHQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPENQAGPGGGGGGTVATAGGASGALSPQTNRNHANKTPTPAMVAAAAAAAAAAAAASLPPPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTATSGIVNPESTCFTLDNGALKPLATALNMANPLLDTAKETSSSSITTEQLAAAASKPRSSPSEGIKRKEATGNRETVPLDLSLSRRSPISALLQRQDLLMANLGLSLGLGKENLLMNENHRVVTPEQIVCAPSLPSSPSMSPSPKRRAMSPAPGRSSSGGGSTASMSPPQQQQQQQQQHLLDNLPPLRSMLPAEFALTESLLAKTNPELALKLAAELANKLAAGFTGSVPTAPAPASAPTTPVAGSTNQPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQEASGTGSGSGGVEGDNANLKSSTPPPGTGSAGAGGVPSSESSPAVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGANAAPAATAAVSAQVPSSDDRLLMVKEKCPKCKSLHDPNQSCPANVVAAGIPTSSTTSVNKCPVCGVVSPSAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEEVAALAAAGTGGGVAVGSGVDIPAVATDQQLLDQHPPQIYNCEYCNYASTYKGNVLRHMKLLHPHVAIINSPSISPESRDQQQQDILSNTQDVVNGEGASFHIKSEPMDHVVAPSTPTLPPPPPTLGLMHENNNSPIATPHIKAEPGLDIDVSPPSSLGVAPPPVSSPVLTAAAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKPHRPEASDSPSPNQMTGSGGAAAAGGVGGLLGMGGAGGVQPLQSPSELMMLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00600575;
90% Identity: iTF_00556091;
80% Identity: -