Basic Information

Insect: Drosophila neocordata
Gene Symbol: ush
Assembly: GCA_018903615.1
Location: JAEIGI010000005.1:1348627-1355320[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0062 0.5 11.0 0.0 1 20 213 232 213 234 0.90

2 9 0.00026 0.022 15.3 0.8 1 23 286 308 286 308 0.98

3 9 0.047 3.9 8.2 1.0 2 21 349 368 349 369 0.92

4 9 0.046 3.7 8.3 2.9 2 21 737 756 736 757 0.93

5 9 0.0085 0.69 10.6 0.0 3 21 815 833 813 834 0.91

6 9 0.025 2 9.1 0.0 2 23 902 923 901 923 0.98

7 9 0.0036 0.29 11.8 1.3 1 23 929 951 929 951 0.99

8 9 0.00063 0.052 14.1 0.8 1 23 1010 1033 1010 1033 0.96

9 9 0.29 23 5.8 0.7 2 20 1154 1172 1153 1174 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0062	0.5	11.0	0.0	1	20	213	232	213	234	0.90
2	9	0.00026	0.022	15.3	0.8	1	23	286	308	286	308	0.98
3	9	0.047	3.9	8.2	1.0	2	21	349	368	349	369	0.92
4	9	0.046	3.7	8.3	2.9	2	21	737	756	736	757	0.93
5	9	0.0085	0.69	10.6	0.0	3	21	815	833	813	834	0.91
6	9	0.025	2	9.1	0.0	2	23	902	923	901	923	0.98
7	9	0.0036	0.29	11.8	1.3	1	23	929	951	929	951	0.99
8	9	0.00063	0.052	14.1	0.8	1	23	1010	1033	1010	1033	0.96
9	9	0.29	23	5.8	0.7	2	20	1154	1172	1153	1174	0.91

Sequence Information

Coding Sequence: ATGGATCTTGGTAAAGAGATTGGTGTGGAGCGAGAATCCAAAGATTTATCCGATCACGAGTTGGGTGAGGAGCAACAGTTTGATGACCAAACTTCCAATAACAACAACAATAATAATAATAATGCTAGCGATCAGGCAACAGAAGCTGAGGAGGAGACAAATTCCTTAGAAGAGTCCTTAGAGGAATCGGAGGAAATAAATCGAATACAGGGCAAGGAGCAAGAAGCAAAAGAAGAAGGAGATGAGAAAGCGATGGCCACAACACCACCACGTAGTCCATTAGCCGAGCCAGAAGACTGTGCTGAGGCAACTGGAATCAATTTAGTCGATGGCATAGTGCCCAAAATAGAGGAACCAGCTACACCGCCCACACCTCCTTCTCCCTGCCCCTCACCAATAAGTCATTCGCCTACCCTTCCATCGCCTCCACCTCCGCTACTACCACCAGTAACGCTGCCCAAATTGCGTTTAAATGCTTTGCTAGCCTCCGATCCTGCACTGAAACCGGATGCAAAGGAGCTTAATCTGTTAGGACCACCAGCTATGACCAAACAAGCACCATCACTACCACCACCAGTACCACCCCAACCCACAGAGCAGCCTGAACTTGTGGAGCCCTTGCTAAAGCCAGCACGATTCATGTGTCTGCCATGCGGCATAGCCTTTAGTTCGCCCTCTACGCTGGAAGCGCATCAAGCCTATTATTGTTCGCACCGGCCCAAGGAAACGCCCGAACAAGATGAGGCCGGAGGAGAGAAGGGAAATGACGGATCAATTTCAAATGCAACCAGCGTTGGTAGTAGTAGCGGCTCCTCTAACGAACCGCCAGCCAAAGTGGCACGGATGGGTAAGCAATATGCTTGCACGCAGTGTTCCTACAGTGCAGATAAAAAGGTCTCTCTCAATCGGCACATGCGAATGCATCAATCCTCGCCAGCAGCAACAACAACCACAGCGGCGACATCCATTACAGCCAATGGCGTGGGATTAGGTATTAATCCCCTACACGAGGAGACCTCTAGTCAACATCAGCAAATCGATCGCTACTGCAGCGACTGTGATATCCGTTTCAATAATATCAAAACGTATCGAGCCCATAAACAACATTATTGCAGTTCTCGACGTTCAGATGGCCAATTGACACCGAAACCAGAAAGCCAACCTGGCGCCGCTGGTGGCGCTGGAGGGGGAGCAACTGTTGCAAATGTTGGTGGAGCCAGTGGTGCTCTAAGTCCCCAAACCAATCGCAATCATGCTAATAAGACCCCAACTCCAGCTATGGTGGCAGCTGCGGCTGCAGCTGCTGCTGCGGCGGCTGCCGCTTCCTTGCCACCACCACCTCAGCCATTTTTGGCACTGCCCACTAATCCAATCATAATAGTGCCCTGTTCATTAATAAGGGCGGCCAGTCTCATACCAGGACCACTCACCACTGCCACCTCAGGCATAGTTAATCCAGAATCCACCTGCTTTACGCTAGATAATGGAGCACTGAAACCGCTAGCAACGGCCTTAAATATGGCCAATCCATTGCTGGATACAACCAAGGATCAAATATCTTCATCCTCTATCACAACCGAACAGCCAGTAGCAGCAGCTAAGCCTAGAAGTAGTCCTTCCGAAGGAATCAAACGCAAAGAACCCACTGGCAGTCGTGAAACGGTACCCTTGGATCTTTCACTATCGCGTCGTTCCCCAATCTCAGCTTTGCTTCAGCGCCAGGATCTATTAATGGCTAATCTAGGTCTCAGTTTGGGTTTGGGCAAAGAGAATCTCTTAATGAATGAGAATCATCGCGTGGTTACACCCGAACAGATTGTATGTGCCCCATCATTGCCCAGCAGTCCATCGATGAGTCCCTCACCAAAGCGTCGGGCTTTAAGTCCTCCGCCAGGACGTAGCTCTTCGGGCGGTGGAAGTACGGCTTCCATGTCGCCACCCCAACAGCAACAACAACAGCAGCAGCATTTGTTGGACAATTTGCCTCCTCTCCGATCCATGTTGCCAGCGGAATTTGCCTTAACCGAATCTTTGCTGGCCAAAACTAATCCAGAATTAGCACTAAAGTTGGCTGCCGAATTGGCTAACAAATTAGCAGCTGGTTTTACAGGATCAGGTCCAACAGCGCCGCCACCAGCATCGGCACCCACTACACCTGTCGCTGGTTCCGCCAATCCGCCGCAGATCTACGTAAAGCAGGGTGTGTCCAAGTGCAAAGAGTGCAATATCGTCTTCTGTAAATATGAGAACTATTTGGCTCATAAGCAACATTATTGCTCGGCACGAAACCAGGAGACAGGAGCAGGATCAGGAACTGGCGGTGTTGAAGGGGATAATTCCAATTTAAAATCTTCAACGCCACCAGCGGGAACAGGAGGAGCAGGGGCCGGTGGAGTAGCATCATCCGAATCTTCACCTGCTGTGGCATATCAGCAATTAATTTGTGCTGCTTGCGGCATTAAATACACATCCCTTGATAATCTACGAGCACATCAAAACTATTACTGCCCCAAGGGAGCTAATGCGGCTCCAGCTGCAGCGGCTGCTGCTGCGATATCTGCACCGTCTTCCGTCTCGGATGACCGGTTGCTAATGGTGAAGGAGAAGTGCTCAAAATGCAAGAGTTTACATGATCTAAATCAATCCTGTCCAACAAATATAGTTGCAGCTGGTGCCACAACTAGTTCCACCACTAGCGTTAATAAATGTCCCGTATGTGGTGTGATCAGTCCCAGTGCTGCTCTCGCCCGCAAACATATGGAAATGCATGGAACGGTTAAGGCATTCCGCTGCAGCATTTGCCAGTACAAGGGAAACACATTGCGTGGGATGCGTACCCACATACGCACTCATTTTGACAAGAAGACCAGCGATGTCAACGAGGAACACTACATGACCTGCATTTTCGAAGAAGAGGCAGCAGCCCTAGCAGCAGCAGCAGGATCTGGAGGGGGAGTAGGAGGTGGGGTAGATATACCAGCAGCTGCCACAGATCAGCAACTTTTAGATCAGCATCCTCCTCAGATTTTTAATTGCGAATATTGCAACTATGCCTCCACATACAAGGGCAATGTGCTGCGTCACATGAAGCTCTTGCATCCACATGTGGCTATTATAAATTCACCATCGATATCGCCCGAATCAAGAGATCAGCAGCAACAGGACATCCTTTCAAATGCGCAAGTCTTACCTGACGTAGTAAACGGAGAAGGTGCCAGTTTTCATATCAAATCGGAGCCCTTGGATCATGTAGGAGGACCACCTACACCAACTCTAACACAACCTCCACCCACCTTAGGTTTAATGCATGAGAACAATAACTCTCCTATTGCCACGCCGCACATTAAAGCTGAACCTGGTCTGGATATTGATGTGTCTCCACCCAGTTCCATGAGTTTGGCACCGCCACCTGTATCGTCGCCTGTTTTGGCGGCCGCTGCAGCGGAGGCCATGAAGAAATACTGTTCCACCTGCGATATATCCTTTAATTATGTGAAAACTTTCTTGGCCCATAAACAATTTTATTGTAAAAGTAAATTACACCGACCCGAGGCAAGCGATAGCCCCAGTCCCAATCAGATGACTGGGGGTGGTGCTGTAGCTGGTGGTGGGGCGAGTGGTTTGTTGGGAATGGGTGGCGGTGGCAGTGTCCAGCCACTGCAATCTCCCAGCGAATTGATGATGTTGCAAAAGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MDLGKEIGVERESKDLSDHELGEEQQFDDQTSNNNNNNNNNASDQATEAEEETNSLEESLEESEEINRIQGKEQEAKEEGDEKAMATTPPRSPLAEPEDCAEATGINLVDGIVPKIEEPATPPTPPSPCPSPISHSPTLPSPPPPLLPPVTLPKLRLNALLASDPALKPDAKELNLLGPPAMTKQAPSLPPPVPPQPTEQPELVEPLLKPARFMCLPCGIAFSSPSTLEAHQAYYCSHRPKETPEQDEAGGEKGNDGSISNATSVGSSSGSSNEPPAKVARMGKQYACTQCSYSADKKVSLNRHMRMHQSSPAATTTTAATSITANGVGLGINPLHEETSSQHQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPESQPGAAGGAGGGATVANVGGASGALSPQTNRNHANKTPTPAMVAAAAAAAAAAAAASLPPPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTATSGIVNPESTCFTLDNGALKPLATALNMANPLLDTTKDQISSSSITTEQPVAAAKPRSSPSEGIKRKEPTGSRETVPLDLSLSRRSPISALLQRQDLLMANLGLSLGLGKENLLMNENHRVVTPEQIVCAPSLPSSPSMSPSPKRRALSPPPGRSSSGGGSTASMSPPQQQQQQQQHLLDNLPPLRSMLPAEFALTESLLAKTNPELALKLAAELANKLAAGFTGSGPTAPPPASAPTTPVAGSANPPQIYVKQGVSKCKECNIVFCKYENYLAHKQHYCSARNQETGAGSGTGGVEGDNSNLKSSTPPAGTGGAGAGGVASSESSPAVAYQQLICAACGIKYTSLDNLRAHQNYYCPKGANAAPAAAAAAAISAPSSVSDDRLLMVKEKCSKCKSLHDLNQSCPTNIVAAGATTSSTTSVNKCPVCGVISPSAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEEAAALAAAAGSGGGVGGGVDIPAAATDQQLLDQHPPQIFNCEYCNYASTYKGNVLRHMKLLHPHVAIINSPSISPESRDQQQQDILSNAQVLPDVVNGEGASFHIKSEPLDHVGGPPTPTLTQPPPTLGLMHENNNSPIATPHIKAEPGLDIDVSPPSSMSLAPPPVSSPVLAAAAAEAMKKYCSTCDISFNYVKTFLAHKQFYCKSKLHRPEASDSPSPNQMTGGGAVAGGGASGLLGMGGGGSVQPLQSPSELMMLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00600575;
90% Identity: iTF_00501345; iTF_00591239; iTF_00578060; iTF_00483983;
80% Identity: -