Dsta008218.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila stalkeri
Gene Symbol
RREB1
Assembly
GCA_035047405.1
Location
JAWNPR010000061.1:26220298-26226879[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0027 0.2 12.3 1.0 1 21 239 259 239 261 0.96
2 13 0.00032 0.024 15.2 0.2 1 23 271 293 271 293 0.98
3 13 7.8e-05 0.0057 17.1 7.3 1 23 299 321 299 321 0.98
4 13 0.043 3.2 8.5 0.8 2 20 534 552 534 554 0.93
5 13 0.0085 0.62 10.7 0.1 1 23 706 728 706 728 0.97
6 13 1.2e-05 0.00087 19.7 0.7 1 23 738 760 738 760 0.99
7 13 0.0008 0.058 13.9 2.0 1 23 766 789 766 789 0.97
8 13 0.0029 0.21 12.2 2.0 1 23 1050 1073 1050 1073 0.95
9 13 8.3e-05 0.0061 17.0 0.3 2 23 1419 1440 1418 1440 0.97
10 13 0.14 10 6.9 6.3 1 23 1446 1469 1446 1469 0.97
11 13 3.1 2.3e+02 2.7 4.2 1 23 1594 1617 1594 1617 0.88
12 13 0.0081 0.59 10.8 0.5 3 23 1687 1707 1685 1707 0.96
13 13 0.0013 0.094 13.3 4.8 1 23 1713 1735 1713 1735 0.99

Sequence Information

Coding Sequence
atGCTGgccacacagcagcaacagcagcagcagccacagcagcaacatacagcagcagcagcggcagcagtgaCTCTTGAGGATGCGGTTATGGAGCAGCGACAGCGTCGTGACTCCAGCACCTCGGAGTCATCGCTGGAGCATCTGGATCTGGGTCGCACGCCAAAGAAgctgagcagcaacagcggtgCGTCGATGCCGACGTCGACGCCGCACGTTGAGTCGGCGTCGCGAAAGCGCAAgatgcagcgacagcagcaacagcaaatctTGTACTCAGACGAGGAGgacgagcaacagcagcaacagcagcagcagcaacaacagcagcaacagttgctggaACAGTCGGTGCATCGCAATCGCCATAAGCAGCGCCGCAGCGGTAATGCAGTCACGGCCGCTGCCAGCGCCAGCATCGTCGTCGACTACAGCGTCGGCAGCGATGCCAGCTCGTTGCGCAAAAAGTTTCGCCTGAATCGCAGCAACATCAGCGCCCACAACGGCGATCTCTCCGAGTCGGGCTTTGTCGATGGCAGCGCACACAGCGGCTTTTTGCTCAGTGCCAGCGGCGCAGCGCAGTCGGCGAcgacagcgcagcagcagcagcaacagcaacctgGCTCGGGCAGCAGCTCCGGCGGCTCCTCGCCGCAAGGCCTCTGCCATTCGAGCGCTGAGTCTGGCATCGGCGCCGGCGACGAGCACAGAAAATATGTCTGCCCCATCTGCGAGGTCGTCTCGACCACGCCCCACGAGTTCACCAATCACATTCGATGCCACAACTATGCCAATGGCGACACCGAGAACTTCACCTGCCGCATTTGCTCCAAGGTACTCTCGTCAGCCTCCTCGCTGGACAGACACGTCCTGGTGCACACCGGGGAGCGACCCTTCAACTGTCGCTATTGCCATTTGACCTTCACGACAAATGGCAACATGCATCGGCACATGCGAACACAcaagcaacatcagcaacatcagcagcaacagcaacaacagcagcagcagcagcagcagcaacaacagcagcagccacagtcacaacaactgcagcaacagcagcagcagcaacagttgcagcgaCATCAGCAACATGTGTCATCAAATGCTGTGGGTCAGCGTGCCGAGAGCTATGAAAGCGATGCCAGTTGCTCCACGGATatatccagcagcagcagcagtgcagccagcaacaacaacaacagtagccaagcgaacaacaacaacaatgatgagcagcaactgaagctgaagaccaacatcaacaacaacaacatcattgTCAGCGACGAGCGAGCACTGGACATGGACGCCGATGTCGATGGCGATGgtgatggcgatggcgatggcgatggcgatggcgatggcgatggggAGGAGGCAGCGGATGGGGAAAGCGTGGATGTGACACAGATGATAACGAGCACACCCGACGTGGCCACGCTGCTGGCAACATCGTCGGGCAACAGCAGCCCGAGAACGCCGGAGCCCGAGTCGGAGTCGTTGCCCAGCTGCCCTGTCTGCAATACTGGCGAGTTCGAGACGCTGGCCGCGCTGTACGCCCACCTGGAGGCGGAGCATGGCGATATACCCGCCAAATGTCGGGAGTGTGAGGTGATCTTTGCCacgcagcggcagctgcaggcGCATAGCTGTCGGGGATTGcagttgccgccgctgctgggCGCCAGCTCATCGCCGCTTCACAAGCAGGAGCCGGCGGATGAGGAGGATGAGGAGCAGCAgttgcaccagcagcagcagcgcgatGACGACGCCGAGGCTGAGGAGGACGAGGAGGAGATGCGCATGCAGGCAAACAGCGAGCGCGACGAGTTCTTTCAGCAACTCTATCTCAAGGGCAAGTCGAGTGGCTCCTCGCTGCCGTCGCCCATCAAGCATGAGCCGTCGGAGCAGCGCCAAGACCTGGCCGACATACAGAGCATCCTGCACATgaccagctccagctgcacgTCCAGTTTCCTGCGCAACTTCGAGCAGAACGTGAACACGCCCTGCTCCAGCCAGTACAGCCTGGATGGACGCGACGGCGAGGAGGAGGCCCAGGATGCCTTCACCAGCGAGTTCCGGCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCTCCGCCGTCTTTCCCAATCTGCGCGCCCTCAAGGGCCACAATCGCGTCCATCTGGCAGCCGTCGGTGCCGCCGGCCCCTTTCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCTCTGGTGCGGCACATGCGCACCCACAACGGCGATCGGCCGTACGAGTGCGCCGTCTGCAACTACGCATTCACCACGAAGGCCAACTGCGAGCGCCATCTGCGTAATCGGCACGGCAAGACGAGCCGCGACGAGGTGAAGCGCGCGATCGTCTATCACCCGGCCGAGGATGCCAGCTGCGAGGACATCAAGCCCAAGATGGACCCCGATCTGTCGGAGCTCAGCTTTCGCTCACTCAGTCCCGCGCCGTCGACGACCAATGTGGAGGCGAGCTCTCAGCTAAAGCACATGTTGCTGGCCGAGACGcccagcaagcagcagcagcagcaacaacaacagcagcagcagcagcagcagccgccgcagccACCGTTAAAGATTCAAGTAAAGAGTTTGGATCAGCTGGTGGAGAAGCCGCTGGCACCTGCCATTGATCTCAGCATGGATGTGCTGGATCTCAGCAAGAAGCCGCAGCGCGAACATGACTTACtcttgcagcaacagcagcaacaacagcagcagcagcaacagcagcagcagcagcagcagcagcaacaacaacagcagcagcagcagcaacagttgctcttCAATCCAGGCGATGCAGCTACGCAGTATGTGCAGCTGTTGCGCAATCTGATGCTGCATCAATCCTCCGGCTTTCCGTTCTTTGGTCTGATGGCGCCGCCACCGGCTGCTGCGCTGGATAAGTCAGCGCCAGCGATTGCAGTGCCAGCGAcgccagcaacagttgctgcaggGCCACCAGCCCTAGGCCTGCCCTTGAGCGGCATGGGCGTGCCAGTGCCAGCCGCCGGGCCAGTCAAGATGGTCATCAAGAACGGTGTGCTGATGCCCAAGCAGAAGCAGCGTCGCTACCGCACCGAGCGTCCCTTCGCCTGCGAGCACTGCTCGGCCAGATTCACGCTGCGCTCGAACATGGAGCGTCACgtcaagcagcagcatccacagTTCTATGCACAGCGACAGCGTAGCGGACACCACGTGATGCGTGGGCGTGCAGCCAACTCGGGTGCtgcccaagcagcagcagcagcggcggcagcggcagcagcagcagcagccgcagcagcagccatgacAAATCTGcaccagcaacatcagcagcaacagcagcagcatccgccTATATCTGAGCAGGTGAAGTACGCAATCCTGGCACAGCAATTGGCGCGCAAGGATACGGATTTGTTGCAGCAGGCGCTGGCCCATGGCTCCAGCAGCGTGGCCGTCAATCCACTGTTGCACTTCGgctatagcaacaacaacaacaacaacaacaacaatagcggcaacggcagcagcagcagcgatgtcaatggcaacaatcaggcgcagcagcaaccgtTGTCCATAGATGATGATGAGCCGCCCAAGCTGATCATAGACgaggacgatgatgatgatttcgATGACATagatgaggaggaggaagaggaggaggacgaGGAGCTAGACCaagacgagcagcagcagcagcaacaacagcagcagcagcagcagcagcagcaggaggaggagcaacagcagcaacacgaacagcagcagcaacagcaacagcagcaagtgcagccaattgaaattgatgccAAAGACGAGCCAGAGCCGCTCGTCGAGTCGATTGAGCCGAAAGTGAAGCCCAGCGGCGAGCCATCGACAATGAAGACTATGATTGCCCAGGCCGAGTCGGTGGCCAAGTCATTGAAGGAGGTGGCCAGCTCGCCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAGCTGGTGGACAATGCCACCAGCAACCAGGTGTCGTTCAACAGCTACTTCCGTCCCAGCGACGTGGCCAACCATATGGAGCAAAGCGACGAGGAGGGTCTGGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACCGAGGACgtcactagcagcagcagctgcagcgaacCGAAGAAGAAGTCCGCCTACAGTCTGGCGCCCAATCGTGTTAGCTGCCCGTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGGCGTCACATCCTCACCCACACGGGCCAGAAGCCGTTCAAATGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGACCGCCATCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCCGTCTACGTGCCCACCGAGGACGTCAATGAGCCGATACCCGTGCCCAAATCCGTCGAGGAGATCGAGCTGGAGGAGCAGCGCCGCCGCAAAGCTGCCGAGCAGGAGCGCCAGCTAGAGCTGGAGCGCGAGCGAGAGCGCGAACGTGAACTGGAGCGGGAGCGTGAGCTGGAGCGCGagcgcaagcagcagcagctcatccAGCAACTGACGGCGGCGGCTCAGCTCAGCCAGCAGATGGTGGCCGCAGCTCAggccgctgccgccgcagcTGCCACCACCAGTGGCAACAatggcagcagtagcagcattAGCAGCGCTGCAGCCGAGGCCAATGGCAGCGAGCTGCCCTACAAGTGTCACCTGTGCGAGTATTCGTTCGGGGAGCGCATGCAGTGCCTCGACCACATCAAGCAGCAGCATGCCCAGGAGtttgctctgctgctggccaaggGCGCCATCGAGACGGAGCAGgaggtggcagcagcagcagcagccacagcaaatgcagcagctgctgctgctgctgctgccgctgctgcagcaacctCGGCTGGCGTCTCCGAGGATGAGTCCAGCACGGGCCGCAGCTCGGGCAAATATCCGGATTACAGCAATCGCAAGGTGATCTGCGCCTTCTGCGTGCGTCGCTTCTGGTCCACCGAGGATCTGCGCCGTCACATGCGCACCCACTCGGGCGAGCGTCCGTTCCAGTGCGAGATCTGCTTGCGCAAGTTCACGCTGAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGTGGACGCAGTCACAATGGCGAGCCGGGTGCCTCCGATTGCTCCGATGACGAGCAGATGGCCACGCCGCCTACAACACCAACACCCACGGccatgccaatgccaatgccaatgcccatgcccatgccaatgcccagcaacaacaacaataacaacacttgccacaacaacaacaacaatacgaacaataacaacaacaacaacaacaacagtaagaGCGTGCGTCTGCCCAAGCTACATGAGCTGCTGGACAAGGCGAACGAATGGCGCGTCAGTCGCCACGGCGAGCACAAGGAGAACATTGCCGAACCCTCGGCGcccgcaacagcagctgctgtgggcgtggccagcggTGATTTCCTGGGCAATCTGCTCGGCATCACCGACCAGGGCATACTCAACAAGCTGCTCAGCTCACCCGACGAGGCCGCCAAACTGTTGGGCGTCGAGAAGTGA
Protein Sequence
MLATQQQQQQQPQQQHTAAAAAAVTLEDAVMEQRQRRDSSTSESSLEHLDLGRTPKKLSSNSGASMPTSTPHVESASRKRKMQRQQQQQILYSDEEDEQQQQQQQQQQQQQQLLEQSVHRNRHKQRRSGNAVTAAASASIVVDYSVGSDASSLRKKFRLNRSNISAHNGDLSESGFVDGSAHSGFLLSASGAAQSATTAQQQQQQQPGSGSSSGGSSPQGLCHSSAESGIGAGDEHRKYVCPICEVVSTTPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQHQQQQQQQQQQQQQQQQQQPQSQQLQQQQQQQQLQRHQQHVSSNAVGQRAESYESDASCSTDISSSSSSAASNNNNSSQANNNNNDEQQLKLKTNINNNNIIVSDERALDMDADVDGDGDGDGDGDGDGDGDGEEAADGESVDVTQMITSTPDVATLLATSSGNSSPRTPEPESESLPSCPVCNTGEFETLAALYAHLEAEHGDIPAKCRECEVIFATQRQLQAHSCRGLQLPPLLGASSSPLHKQEPADEEDEEQQLHQQQQRDDDAEAEEDEEEMRMQANSERDEFFQQLYLKGKSSGSSLPSPIKHEPSEQRQDLADIQSILHMTSSSCTSSFLRNFEQNVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDASCEDIKPKMDPDLSELSFRSLSPAPSTTNVEASSQLKHMLLAETPSKQQQQQQQQQQQQQQPPQPPLKIQVKSLDQLVEKPLAPAIDLSMDVLDLSKKPQREHDLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLLFNPGDAATQYVQLLRNLMLHQSSGFPFFGLMAPPPAAALDKSAPAIAVPATPATVAAGPPALGLPLSGMGVPVPAAGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAANSGAAQAAAAAAAAAAAAAAAAAAMTNLHQQHQQQQQQHPPISEQVKYAILAQQLARKDTDLLQQALAHGSSSVAVNPLLHFGYSNNNNNNNNNSGNGSSSSDVNGNNQAQQQPLSIDDDEPPKLIIDEDDDDDFDDIDEEEEEEEDEELDQDEQQQQQQQQQQQQQQQEEEQQQQHEQQQQQQQQQVQPIEIDAKDEPEPLVESIEPKVKPSGEPSTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSCSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVNEPIPVPKSVEEIELEEQRRRKAAEQERQLELERERERERELERERELERERKQQQLIQQLTAAAQLSQQMVAAAQAAAAAAATTSGNNGSSSSISSAAAEANGSELPYKCHLCEYSFGERMQCLDHIKQQHAQEFALLLAKGAIETEQEVAAAAAATANAAAAAAAAAAAAATSAGVSEDESSTGRSSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGEPGASDCSDDEQMATPPTTPTPTAMPMPMPMPMPMPMPSNNNNNNTCHNNNNNTNNNNNNNNNSKSVRLPKLHELLDKANEWRVSRHGEHKENIAEPSAPATAAAVGVASGDFLGNLLGITDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00540546; iTF_00473253; iTF_00509994;
90% Identity
-
80% Identity
-