Basic Information

Insect: Drosophila stalkeri
Gene Symbol: hang
Assembly: GCA_035047405.1
Location: JAWNPR010000061.1:18757482-18769474[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.37 27 5.6 1.0 3 23 496 517 495 517 0.93

2 18 1.1 77 4.1 3.2 3 22 624 643 622 643 0.89

3 18 0.00079 0.057 14.0 3.3 1 22 741 762 741 764 0.90

4 18 0.076 5.6 7.7 0.1 2 21 776 795 775 796 0.93

5 18 0.00091 0.067 13.8 0.2 2 23 931 953 930 953 0.95

6 18 0.0026 0.19 12.3 0.1 1 23 961 984 961 984 0.96

7 18 0.0002 0.015 15.8 0.2 2 23 1070 1091 1069 1091 0.97

8 18 0.00038 0.027 15.0 2.9 2 23 1190 1212 1189 1212 0.97

9 18 0.03 2.2 9.0 0.2 2 23 1221 1243 1220 1243 0.95

10 18 0.0016 0.12 13.0 0.1 1 23 1256 1279 1256 1279 0.97

11 18 0.00016 0.012 16.1 1.1 1 23 1327 1349 1327 1349 0.99

12 18 0.0025 0.19 12.4 0.9 1 23 1357 1380 1357 1380 0.96

13 18 0.065 4.7 7.9 0.3 2 19 1388 1405 1387 1406 0.94

14 18 3.5e-05 0.0025 18.2 0.4 3 23 1503 1523 1502 1523 0.98

15 18 0.0066 0.48 11.1 0.1 1 23 1558 1580 1558 1580 0.97

16 18 0.00078 0.057 14.0 0.6 2 23 1667 1689 1666 1689 0.93

17 18 0.0084 0.61 10.7 0.3 3 23 1745 1765 1745 1765 0.98

18 18 2e-05 0.0015 19.0 1.6 1 23 2235 2257 2235 2257 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.37	27	5.6	1.0	3	23	496	517	495	517	0.93
2	18	1.1	77	4.1	3.2	3	22	624	643	622	643	0.89
3	18	0.00079	0.057	14.0	3.3	1	22	741	762	741	764	0.90
4	18	0.076	5.6	7.7	0.1	2	21	776	795	775	796	0.93
5	18	0.00091	0.067	13.8	0.2	2	23	931	953	930	953	0.95
6	18	0.0026	0.19	12.3	0.1	1	23	961	984	961	984	0.96
7	18	0.0002	0.015	15.8	0.2	2	23	1070	1091	1069	1091	0.97
8	18	0.00038	0.027	15.0	2.9	2	23	1190	1212	1189	1212	0.97
9	18	0.03	2.2	9.0	0.2	2	23	1221	1243	1220	1243	0.95
10	18	0.0016	0.12	13.0	0.1	1	23	1256	1279	1256	1279	0.97
11	18	0.00016	0.012	16.1	1.1	1	23	1327	1349	1327	1349	0.99
12	18	0.0025	0.19	12.4	0.9	1	23	1357	1380	1357	1380	0.96
13	18	0.065	4.7	7.9	0.3	2	19	1388	1405	1387	1406	0.94
14	18	3.5e-05	0.0025	18.2	0.4	3	23	1503	1523	1502	1523	0.98
15	18	0.0066	0.48	11.1	0.1	1	23	1558	1580	1558	1580	0.97
16	18	0.00078	0.057	14.0	0.6	2	23	1667	1689	1666	1689	0.93
17	18	0.0084	0.61	10.7	0.3	3	23	1745	1765	1745	1765	0.98
18	18	2e-05	0.0015	19.0	1.6	1	23	2235	2257	2235	2257	0.99

Sequence Information

Coding Sequence: ATGGGAGTTGCAGTTGTTACCAGTTGTCTGCGTCCCGCATCGAATTTCGGATACACATCATCCATGCCCAGGCCCATGCAAGTCAAGTTCAGCTCCGAAGATCAGGCGGCGTTGCTGGACAGGCTGTGCCCGAGCGACGATTTAATTCTGatCACGCCATTGGATCGTCTATCCCTGCATATTTGCCATGCCTGCATCAGCTATCTGAACTCCTGGCAGAGCTTTAAGAATCGCTGTCTCAGCTCACAGACCAAGCAACGGCAGTGGCTGGACAGCGATAAAAGCAAGCAGCAGACGCTTCTCGGATATTTGGATTTGAACAAAACGGAGAATGGCAGCGCCattgaacagcagcaacagcagcagcacgaatCGAATATCGATTCGACAATGACTGCAGCTGAAAAGGCGTCCGCCAACATTTTGGATGGCATTCCTTCGTTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCcaaagcaacagctacaacagcaacaacaacaacagctacaacagcagcagcagcaacaacaacagcagcagcaggtgcagcatgcagcaagagcagcaagcGCGGCGGCGGAATCACAGCAAACTCTTCAGACCCTTTTATTGCAGGTGCCCTCAGTGGCAGCGACCtcagcccagcagcagcagcagcaacaacaacaacaacagctacagcgcAAATatcaacagcaccagcagcaacgtgtcaagcaacaacattaccaacaacaacatcatcagagccaacaacaacaacagcagcatcagcgctTGAGTCGCATTCGTCAGCCACGACGCCAGCAACAGGCGACAATGTCTGCCCAGCGAATGGTCAGATTTAAgccgaaattgtatttgccATTGGATATAGCGGTGCCGCCGCTGCCACCGCTGTTGCCGACACCGACGTcgacacaacagcagcagcagcctgagACTGTTGCTACTGGTGCTAAGTTggcgccgttgccgttgccgttgtcgttgccgcTTGATTTTAGCCAGAGTCAGTGTCAGCATCCGAATTCGAATCAGAGTCAGCAGAAACATGGCAGcgtgttgccgttgccgccgTCGACGCCgctgttgccgccgctgccaGCTGTAACAATGACTAGCAACGCCGCTGCCACTagcgctgcctctgccactaaCGCTGTATCTGCTTctgccgcagccgcagtcacGACTCCTCTGCTCATGCCGCCGCTGCCCGCCGTGCCCATCAAGGATGAGCCCATTGACGAAACGGACGATGACTTTCAAATGAAGTGCATAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCATGAGGGCGATGTGCCACTAATGACCTCCGACTATGATTACACGCCGCAACATGCCGTGACGGCGGTTGTGGCGGCGGCATCGCTACCCGCCAGCGCGGTTGCAAATGTGGCCGCCGCTGGCGACTCAAAGGTGGCCAGCTGTCGGGCCTGCAGTCTGCAGTTCTCGACGCGCGCGAATGCCCGACGCCACGAACGCAATCTGCATCCGAATCTGTTTCAATTGTCGACAGATTCACCCAACAATACGCCCATCACAAAACCGACGCCCGCACTGGCCGCTGCTCTGGAAATTCAGCGTGccgcagcggcggcagcagccacCGCGGAGGCAACCAAAGCCGCCGCCGGCGGTAACATATCAGCGCAAAAGTATCGCCAGGTGGTAATGAATACGTTCATTAAATGCGAAAATGGCGGCTTCGACTACGACAATCCGGAGCAATATCAGCAGCTGCTCACTCGCGACAAGGTGGAGTTCATACAGGAGAACAACGAGTTTCTAGAACAATACCAAACAATGACGTGTCGCTGCTGCAATAAGTACTTCAATACCTACAAGAACTTCATGGCGCACGTGCGTAAAAAGTATCCGCTGCTGCCGCGCAATCTATGCTTCAACTGCCTCAAGATGAACGACTCAAAGGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGCGTGCTGAACGCGCTGCGCCTGAAGCAACCCAATTTTTCGCACGCCAATGCATCCGGAGTGGCTGTAACTGCCGATTTGAGTGTTGGCCAggccgccgcagcagctgcagtatCGGCACATGAAACGTCATCGGAGCGACCAGAGAAGCTGCGTGCCAAGGAACTATTAGTGAACAAGCTGTACGAGTGTAAGCTTTGCCCAAAGGGCTTTCGCACCAAGCATGAGTTCCGTACCCATGTCTATGACAAGCATGCGGATGTACAGCGCAAGGATAACAATTCGATACAGTGCACCTTCTGCGGACTGGACTTTGCCGATCCCGTGGATCGACGTCGTCACTACAACAACATGGAGTGTATTGTGCGGCTGCGTTGCATGACGTGCGATGCTAAGCTGGAGACGCATCAGCGCTTTCTCGATCACGTCTATCAGGATCATCTGGGCGGCGTGAGCAGTGATAATGCTTCGACGGCGAACAGCGGCATGGACCATTCCCCGGGCAAACGCAGCCTGCTGGGCGCCTTAGGCATTGGCATGAGTCAATCATCGAATGATGAGTCACGCAGCAGCACCcagcacaataataataatgctgtGGAAACGGCGTTCACCTCGACACCGAAgccagctggagcagcaggcgGCGGAGCAacatctgctgcagctgcagctgcatcggCCATCAGTGGCGGCTCCACGTCCGGCAGTCGCGATGCACCCAAATCGCAGTATTTCTCCCGCATGCCACAGGTGTGCCCCATCTGCGGGCAACagtacaacaactacaacaacgtGCTGCGCCACATGGAATCGAAGCATCCCAACAAGCTGCCCGAAACATACAAGTGTGTGCGCTGCGGCCTGGGCTATCCGCGAATCTCCTATCTGCGCGAGCACATGATCAATGTGCATGGCGTGGACAAGAATCGGCATTCAGGCGGCTTTGAGTACATTGTGAATGCGGACGCAGTGAAGCTGGCGGATGGCAGCATGCCCAATGTCTATACGGGCCGATATGATTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgatgaagatgaagaggaAACTGGAAGCGTTGCCAAAAAGATGCGATTGgatgacagcagcaacaacagcagcatcaacatgAACATTGCCAATCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTgttcagcaacaacattggCCTGTCGAATCACATGCGCTCGCATTATACAGCCGCAACGGCAACGAATGCAGCACTGGCGGCTGCCAATCGTATGACGCCGAAATCTTTGACAATTACCGCAACGCCACCATTGGAGACGACAGCAACGTCTACAGCAACAGGAGCgcctgccacagcagcagcagcaacaacatccggagcagctggagctggagttggagcagcaacagcaggctcTGGCACCCTGCCACCTGCAATGGTACATCAGACGCCACAGGAGCAGGCCGTATTTCGGCGTAGCCTGGATCAGGCGGCCGATCGTCGCTTTCGCCGTATGCGTTGTCGCATCTGCCAACGTCGCTTCAGCTCGAAGAAATCGTATCGCTATCACATGCTCACCGACCATCAGGTACAGAACGTGCAGTTCATCAAGTGCAAGCTATGCAATGCCGAGTTTGCCTACGAGAAGGGTCTGAAGGTGCATCTGTTCAAGGTGCACGGGCGCGCCATCAAGGACGAGATGATTGTGAAGCAATTCGAGTGCGATATTTGCTCGATTGTCTACAGCTCCGAgctggagctgcagcagcataaGCGCAGCGTGCACAAGTCACATGATGCTGCCTCCTCCAAATCATCCACAACCAAATCATCTACCGCTACCTCAGCTGCTGACCTGGCGGACACATCCGGTGTGGGTGCAAATGCGGGAGTGGCCACCAGTGCGACCGCAATGCCGCTCTACTGGTACCAGTGCAAGTACTGCCCCTCAAATTTCAACACCAACAAGAAGCTAGCCATTCACATCAATTCGCACGACGAGTTCGATTCGAATGATTATTCGTGCAAGGATTGCGGCAATGTTTACAGCGGACGCAAGAGCCTCTGGGTGCATCGCTATAAGAAGCATCCGCAGGTGCCAGATCCAGTTGAGTGCACGCTCTGTCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGGAAGCCCATCACTGCCACCGGCGCCCATCAACaggatcagcagcagcaacaacagcaacagctgcaacaacatcGCGCCATATTCAAGCATAAAACGggcgacgatgacgatgaggaAGAGGATGATCAACTGATGCTGCTGGACGATGGTGGCattggcagcgacagcaatgGTGGTAGCAATGCACCGGCTACggccaccaccagcagcagcaataacaatccAAATACGATAAATGCGAGCACACTGAAGATACGCATACCGGAGGTGGCATGCACCATCTGTGGGGCACGCTTCACCGACCAGGAGATGTTTACCAAGCATATACAGAAGCACGAACAGGATCTGTATGTTGACAATCCATTGGCGGCCATGTTCGACGATGGCCCAGCCGATGTGGGACAATTCAAGGTGGAGCGCCAGAACGAAAATGGGGAATATGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGaatctCATCATCGACGGCGAAGCGACAACgctgaacagcagcagcaacaacaacaacaacaattcactGAGCTCCTCATCGATGCTACGCGAGCTGCATGCAGTGGGCCTGATGCCcaaccagcaacagcaccagaagcaactgcaacagcagcagcaacaacaacagcagcagcagcaacagcggaaCAACACGTCGAGCAGCTCGAGCAAATCGATGAAACGAAAACGTGAACTGAAATGCGAATACTGCGCCTCCACATtcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAATCTGCCAGAGCCGCCAGTCATCGAGGTGGATGAGCCGCTGACATGCCGTCGTTGCGGCGATATACGCTTCGATACCAAAGAGCTGTGGATCGAGCATAAGTTGGCGGACGCCAAAGTGGTGCGTCCCTTCTGTCCATTCCAATGGGGCTGTGATCTATGCGGCGAGTACTTATCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAAGAGGATGTGATAGTGCCGGTAGCAGCGGCCAACAAGGCGGTGTTGCCAGTGCTGCCCAATAAGAATGCAACGGCAAAAGCgacagctggagcagctggagcagaagcagcagcagcagctgatacagcagcaacaacagcaggagtTACAGCCAAGGGGGGAGGCATAGTTAGAGCAGCGGCACCAGCTGGCGGCAGAGCGAATAAGAGTAAACAGCAGATGGAGGAGCAGCTGACCATTAAGATGGcaacaaagcagcagcagcagcaacagcaacagcagcagcaagatgATAATGCTGAGCAGGATGATGAGGAGGATGGCAGTGAtatggatgatgatgatgaggatgataGCGATAGTGGTGATGGGGAGAGCACGAGtgcggatgatgatgatgaggacgatgatgacgatgagggCGACGtggatgacgatgatgatgatgaggatgaagATGTGGATGGCGATGTTGttgaacaacaattgctgcagcaaaaacaacaacaacaaaaacaacagcagcagcaacaacaacaacaacaacagaaccTCAACAGCAATAGCGTCGCTGCccacgatgatgatgacgatctCATTGAGGAAGTCATCGAGGAGGATGGCATTGTCGAGGAGCtggacgacgatgatgacgatgagggtgatgatgatggcaaCACAACCGATGAACATCAGCAGCTGGCAACCaatgccaagcagcagcagcagcagcagcagccgcgacGTCTCAACTTTGACTATGCGAGCGCTGCTAGCGCCAAGCtgaatggcaatggcaaacaGACGCCGCAGCAGCTGGCCAAGTCGAAGGGGCAGTCGGGGGTGCTGGTAATGCATAGCTCCGAGGAGGATGAGGATgttggtgatgatgatgaggatgaggagggTGTGGAGGGTGAAGCGATGACCATTGATGATATTATTGAGGAAGATGATGGggaggatgaggatgatgatgtGGTTGGTGTCGATGGTGGTGTTGTTgaagacgacgatgatgatgatgatgatgatgatgatgttgggGAAGATATGGATgaggatgatgacgatgatgatgatgaggacgatgaggaagatgatgatgacgacgatggcGTCAatattggcaacaacaatcgtCGTCGCGACGGTGCTGTGATGGTCAGCGGCATCAGCATTGGCGACGGTGAAGCTGAtgccgatgctgatgctgatgctgatgttgatgctgatgtggATGGTGATGTGgatggtgatggtgatggtgatgTGGATGCTGATGCTACATCATCATCGGGCAGCGAATCAACAACATCGCATTCAATTGGTGAGCGGCGTAAAAAATCAGTAGTTAAATCAGCGGCACATGGCGCTGCCGTTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCAACTGCAGGCACATATTAAAAGCCATTTTCTGAATGGGCCGTCGGCGGGTGGTGGCAgcaccggcagcagcagcgccagcaacagcgccagcaacagcagaagaatTGGTTCCGGGgcgggcagcggcagcagcagcagcagcagcagcggcggcaacagcagcagcggcagcaacagcagtaggaccaacaacaataataataataacaacaacaacaataataataataataataataataataacaataacaaaagcaaaaccaaaaagtCCGGCTTGGATGCAGCGAATGGTGATAgtacagcagctgctgctgcaacatcatcaacaacaacaacaagatcaacgacagcaacagttgccgctgcagcagctgcagcaacagcggctgcTGACGCGGCAAACAGCTTGAACTGA
Protein Sequence: MGVAVVTSCLRPASNFGYTSSMPRPMQVKFSSEDQAALLDRLCPSDDLILITPLDRLSLHICHACISYLNSWQSFKNRCLSSQTKQRQWLDSDKSKQQTLLGYLDLNKTENGSAIEQQQQQQHESNIDSTMTAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQQQLQQQQQQQQQQQQVQHAARAASAAAESQQTLQTLLLQVPSVAATSAQQQQQQQQQQQLQRKYQQHQQQRVKQQHYQQQHHQSQQQQQQHQRLSRIRQPRRQQQATMSAQRMVRFKPKLYLPLDIAVPPLPPLLPTPTSTQQQQQPETVATGAKLAPLPLPLSLPLDFSQSQCQHPNSNQSQQKHGSVLPLPPSTPLLPPLPAVTMTSNAAATSAASATNAVSASAAAAVTTPLLMPPLPAVPIKDEPIDETDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTPQHAVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKQPNFSHANASGVAVTADLSVGQAAAAAAVSAHETSSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCTFCGLDFADPVDRRRHYNNMECIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGMSQSSNDESRSSTQHNNNNAVETAFTSTPKPAGAAGGGATSAAAAAASAISGGSTSGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSMPNVYTGRYDYVMKDLMSITNGGTLDEDEEETGSVAKKMRLDDSSNNSSINMNIANQQKECLICNAVFSNNIGLSNHMRSHYTAATATNAALAAANRMTPKSLTITATPPLETTATSTATGAPATAAAATTSGAAGAGVGAATAGSGTLPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSIVYSSELELQQHKRSVHKSHDAASSKSSTTKSSTATSAADLADTSGVGANAGVATSATAMPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPVECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQLQQHRAIFKHKTGDDDDEEEDDQLMLLDDGGIGSDSNGGSNAPATATTSSSNNNPNTINASTLKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADVGQFKVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNLIIDGEATTLNSSSNNNNNNSLSSSSMLRELHAVGLMPNQQQHQKQLQQQQQQQQQQQQQRNNTSSSSSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDIRFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVAAANKAVLPVLPNKNATAKATAGAAGAEAAAAADTAATTAGVTAKGGGIVRAAAPAGGRANKSKQQMEEQLTIKMATKQQQQQQQQQQQDDNAEQDDEEDGSDMDDDDEDDSDSGDGESTSADDDDEDDDDDEGDVDDDDDDEDEDVDGDVVEQQLLQQKQQQQKQQQQQQQQQQQNLNSNSVAAHDDDDDLIEEVIEEDGIVEELDDDDDDEGDDDGNTTDEHQQLATNAKQQQQQQQPRRLNFDYASAASAKLNGNGKQTPQQLAKSKGQSGVLVMHSSEEDEDVGDDDEDEEGVEGEAMTIDDIIEEDDGEDEDDDVVGVDGGVVEDDDDDDDDDDDVGEDMDEDDDDDDDEDDEEDDDDDDGVNIGNNNRRRDGAVMVSGISIGDGEADADADADADVDADVDGDVDGDGDGDVDADATSSSGSESTTSHSIGERRKKSVVKSAAHGAAVDQSNSSYTCDLCQLCFDSQEQLQAHIKSHFLNGPSAGGGSTGSSSASNSASNSRRIGSGAGSGSSSSSSSGGNSSSGSNSSRTNNNNNNNNNNNNNNNNNNNNNNKSKTKKSGLDAANGDSTAAAAATSSTTTTRSTTATVAAAAAAATAAADAANSLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00476771;
90% Identity: iTF_00493799;
80% Identity: -