Basic Information

Insect: Drosophila buzzatii
Gene Symbol: hang
Assembly: GCA_035045845.1
Location: JAWNOS010000596.1:11387973-11400384[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.38 29 5.6 1.0 3 23 489 510 488 510 0.93

2 18 1.1 85 4.1 3.2 3 22 617 636 615 636 0.89

3 18 0.00081 0.063 14.0 3.3 1 22 733 754 733 756 0.90

4 18 0.079 6.2 7.7 0.1 2 21 768 787 767 788 0.93

5 18 0.00094 0.074 13.8 0.2 2 23 921 943 920 943 0.95

6 18 0.0027 0.21 12.3 0.1 1 23 951 974 951 974 0.96

7 18 0.00021 0.016 15.8 0.2 2 23 1060 1081 1059 1081 0.97

8 18 0.00039 0.03 15.0 2.9 2 23 1188 1210 1187 1210 0.97

9 18 0.03 2.4 9.0 0.2 2 23 1219 1241 1218 1241 0.95

10 18 0.0006 0.047 14.4 0.2 1 23 1254 1277 1254 1277 0.97

11 18 0.00017 0.013 16.1 1.1 1 23 1325 1347 1325 1347 0.99

12 18 0.0026 0.21 12.4 0.9 1 23 1355 1378 1355 1378 0.96

13 18 0.067 5.2 7.9 0.3 2 19 1386 1403 1385 1404 0.94

14 18 3.6e-05 0.0028 18.2 0.4 3 23 1500 1520 1499 1520 0.98

15 18 0.0068 0.53 11.1 0.1 1 23 1555 1577 1555 1577 0.97

16 18 0.0008 0.063 14.0 0.6 2 23 1662 1684 1661 1684 0.93

17 18 0.0087 0.68 10.7 0.3 3 23 1740 1760 1740 1760 0.98

18 18 2.1e-05 0.0016 19.0 1.6 1 23 2229 2251 2229 2251 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.38	29	5.6	1.0	3	23	489	510	488	510	0.93
2	18	1.1	85	4.1	3.2	3	22	617	636	615	636	0.89
3	18	0.00081	0.063	14.0	3.3	1	22	733	754	733	756	0.90
4	18	0.079	6.2	7.7	0.1	2	21	768	787	767	788	0.93
5	18	0.00094	0.074	13.8	0.2	2	23	921	943	920	943	0.95
6	18	0.0027	0.21	12.3	0.1	1	23	951	974	951	974	0.96
7	18	0.00021	0.016	15.8	0.2	2	23	1060	1081	1059	1081	0.97
8	18	0.00039	0.03	15.0	2.9	2	23	1188	1210	1187	1210	0.97
9	18	0.03	2.4	9.0	0.2	2	23	1219	1241	1218	1241	0.95
10	18	0.0006	0.047	14.4	0.2	1	23	1254	1277	1254	1277	0.97
11	18	0.00017	0.013	16.1	1.1	1	23	1325	1347	1325	1347	0.99
12	18	0.0026	0.21	12.4	0.9	1	23	1355	1378	1355	1378	0.96
13	18	0.067	5.2	7.9	0.3	2	19	1386	1403	1385	1404	0.94
14	18	3.6e-05	0.0028	18.2	0.4	3	23	1500	1520	1499	1520	0.98
15	18	0.0068	0.53	11.1	0.1	1	23	1555	1577	1555	1577	0.97
16	18	0.0008	0.063	14.0	0.6	2	23	1662	1684	1661	1684	0.93
17	18	0.0087	0.68	10.7	0.3	3	23	1740	1760	1740	1760	0.98
18	18	2.1e-05	0.0016	19.0	1.6	1	23	2229	2251	2229	2251	0.99

Sequence Information

Coding Sequence: ATGGTTGCCCGCTGCTCAGCGacggcaacgacgacgacggtgGCTCTCTGGACTGCGCCCCCGGCAACGACATCATCATCTACGTCGGCGTCGTCGCAGCAGTCATTGTCGACACGTTGTTGCTGCGTGTGCTTGaTCACGCCATTGGATCGTCTATCGCTGCATATTTGCCATGCCTGTATCAGCTATCTGAACTCCTGGCAGAGCTTTAAGAATCGCTGCCTCAGCTCACAGACCAAGCAACGGCAGTGGTTGGACAGCGATAAAAGCAAGCAGCAGACGCTTCTCGGATATTTGGATTTGAACAAAACGGAGAATGGCAGTGCCattgaacagcagcaacagcagcagcacgaatCGAATATCGATTCGGCAATGACTGCAGCTGAAAAGGCGTCCGCCAACATTTTGGATGGCATTCCTTCGTTGAAGAAACGCAAATCGTTAACAGTTTATGTGAGTCCaaagcaacagctacaacaacaacaacagctacagcagctacaacagcagcagcaacaacaacagcagcaggtgcAGCATGCAGCAAGAGCAACGAGCGCGGCGGCGGAATCACAGCAAACGCTTCAGACCCTTTTATTGCAGGTGCCCTCAGTGGCAGCGACTtcagcccagcagcagcaacaacaacaacagcaacagcgcaaatatcaacagcaccagcagcaacgtgttaagcaacaacattaccaacaacaacatcatcagagccaacaacaacagcatcagcgcTTGAGTCGCATTCGTCAGCCACGACGCCAGCAACAGGCGACAATGTCTGCCCAGCGAATGGTCAGATTTAAGCCGAAATTGTATTTGCCATTGGATATAGCGGTGCCGCCGCTACCACCGCTGTTACCAACACCGACGTcgacacaacagcagcagcagcctgagactgttgctgctggtgctaaGTTggcgccgttgccgttgccgttgtcgctGCCGCTTGATTTTAGCCAGAGTCAGTGTCAGCATCCGAATCCGAATCAAAGTCAGCAGAAACATGGCAAcgtgttgccgttgccattgccattgccgccGTCGACGCCGctgttgccgccgctgccaGCTGCAACAATGACTAGCAACGCCGCTGCTACTAGCGCTGCTTCTGCCACTaacgctgcctctgcctctgccgcagccgcagtcACGACTCCTCTGCTCATGCCGCCGCTGCCCGCCGTGCCCATCAAGGATGAGCCCATTGACGAAACGGATGATGACTTTCAAATGAAGTGCATAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCATGAGGGCGATGTGCCACTAATGACCTCCGACTACGATTACACGGCGCAACACGGCGTGACGGCGGTTGCGGCGGCGGCATCGCTACCCGCCAGCGCGGTTGCAAACGTGGCCGCCGCTGGCGACTCAAAGGTGGCCAGCTGTCGGGCCTGCAGTCTGCAGTTCTCGACGCGCGCGAATGCCCGACGCCACGAACGCAATCTGCATCCGAATCTGTTTCAATTGTCGACAGATTCACCCAACAATACGCCCATCACAAAACCGACGCCCGCACTTGCCGCCGCCCTGGAAATTCAACGTGccgcagcggcggcagcagccacCGCGGAGGCAACCAAAGCCGCCGCCGGCGGTAACATATCAGCGCAAAAGTATCGCCAGGTGGTAATGAATACGTTCATTAAATGCGAAAATGGCGGCTTCGACTACGACAATCCGGAGCAATATCAGCAGCTGCTCACCCGCGACAAGGTAGAGTTCCTACAGGAGAACAACGAGTTTCTGGAACAATACCAAACAATGACGTGTCGCTGCTGCAATAAGTACTTCAATACCTACAAGAACTTCATGGCGCACGTGCGTAAAAAGTATCCGCTGCTGCCGCGCAATCTGTGCTTCAATTGCCTCAAGATGAACGACTCGAAGGCTCTGTTCATATCGCATTTGAAGAAGCGTAACTGCATAAATCTGTATCGCGTGCTGAACGCGCTGCGTCTGAAGCAACCCAATTTTTCGCACGCCAATGCATCCGGTGTGGCTGTAACGGCCGATTTGAGTGTTGGCCAggccgcagcagcggcagcatcggCACATGAAACGTCATCGGAGCGACCGGAGAAGCTGCGTGCCAAGGAATTGTTGGTGAACAAGCTGTACGAGTGCAAGCTGTGCCCAAAGGGCTTTCGCACCAAGCACGAGTTCCGCACCCATGTCTATGACAAGCATGCGGATGTGCAGCGTAAGGATAACTATTCGATACAGTGCACCTTCTGCGGACTGGACTTTGCCGATCCCGTGGATCGACGTCGCCACTACAACAACATGGAGTGCATTGTGCGGCTGCGCTGCATGACGTGCGATGCCAAGCTGGAGACGCATCAGCGCTTCCTTGATCACGTCTACCAGGATCATCTGGGCGGCGTGAGCAGTGATAATGCCTCGACGGCCAACAGCGGCATGGACCATTCCCCGGGCAAACGCAGCCTGTTGGGCGCCTTGGGCATTGGCATAAGTCAATCATCGAATGATGAGTCACGCAGCAGCACCCagcacaacaataataatgctgTGGATGCAGCCTTCACCTCGACACCGAAGCCAGCTGGAGCAGCGGGCGGCGCAGCAacatctgctgcagctgcatcggCGGTCAGTGGCGGCTCCACGTCCGGCAGTCGCGATGCACCCAAATCGCAGTATTTCTCCCGCATGCCACAGGTGTGCCCCATCTGTGGGCAACAGTACAACAACTATAACAACGTGCTGCGTCACATGGAATCGAAGCATCCCAACAAGCTGCCCGAAACGTACAAGTGTGTGCGCTGTGGCCTGGGTTATCCGCGAATCTCCTACCTTCGCGAGCACATGATCAATGTGCATGGCGTGGACAAGAATCGGCATTCGGGCGGCTTTGAGTACATTGTGAATGCGGATGCAGTGAAGCTGGCCGATGGCAGCATGCCCAATGTCTATACGGGCCGTTATGATTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgatgatgatgaagaggAAACCGGAAGCGTTGCCAAAAAGATGCGATTggatgacagcagcaacaacagcagcatcaacatgAGCATTGCCAATCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTCAGTAACAACATTGGCCTGTCGAATCACATGCGCTCGCATTATACGGCCGCAACGGCAACGAATGCAGCACTGGCGGCTGCCAATCGCATGACGCCCAAATCTTTGACAATTACCGCAACGCCGCCATTGGAGACGACAGCAACGTCCACGAGcgctgcagcaacaaaagcgtctgccacagcagcagcagcagttgcagcgaCAGGAACAACATCGGGAGCAGCTGtcgctggagctggagcagcaacaacgggCTCTGGTAGTCTGCCACCCGCAATGGTGCATCAGACGCCACAGGAGCAAGCCGTGTTCCGGCGCAGCCTGGATCAGGCGGCCGATCGTCGCTTTCGCCGAATGCGCTGTCGCATCTGCCAACGTCGCTTCAGCTCAAAGAAATCCTATCGCTATCACATGCTCACCGACCATCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCCGAGTTTGCCTACGAGAAGGGTCTGAAGGTGCATCTATTCAAGGTGCACGGGCGCGCCATCAAGGACGAGATGATTGTGAAGCAATTCGAGTGCGACATTTGCTCGATTGTCTACAGCTCCGAgatggagctgcagcagcacaagcGCAGCGTACACAAGTCCCATGATGCTGCCTCCTCCAAATCATCAACAACCAAATTATCTAGCGCTACCTCAGCTTCTGATCTGGCGGACACATCCGGTGCGGGTGCAAGTGCGGGAGTGGCCACCGGTGCGACCGCAATGCCGCTCTACTGGTACCAGTGCAAGTACTGCCCCTCAAATTTCAACACCAACAAGAAGCTAGCCATTCACATCAATTCGCACGACGAGTTCGATTCGAATGATTATTCGTGCAAGGATTGCGGCAATGTTTACAGCGGACGCAAGAGCCTCTGGGTGCATCGCTATAAGAAGCATCCGCAGGTGCCAGATCCAGTTGAGTGCACGCTTTGTCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATACACCCACCTGCAATCGAAAGCCCATCACTGCCACTGGCGCCCATCAGCaggatcagcagcagcaacatcagcaacaacaacaacagcgagccATATTCAAGCATAAAACGggcgacgatgacgatgaggaAGAGGACGATCAACTGATGCTGCTGGACGATGGTGGCattggcagcgacagcaatgGCGGTAGCAATGCACCGGCTACggccaccaccagcagcagcaacaacaatccaAATACGATAAATGCGAGCACACTGAAGATACGCATACCGGAGGTGGCATGCACCATCTGTGGGGCACGCTTCACCGACCAGGAGATGTTCACCAAGCACATACAGAAGCACGAACAGGACCTGTATGTGGACAATCCATTGGCGGCCATGTTCGATGATGGCCCAGCCGATGTGGGACAATTCAAGGTGGAGCGCCAGAACGAGAATGGGGAATATGCGTGCGATTTGTGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGaatctCATCATCGACGGCGAAGCGACAACGctgaacaacagcagcaacaacaacaacaacaacaattcactGAGCTCCTCGTCGATGCTACGCGAGCTGCATGCAGTGGGCCTGATGCCcaaccagcaacagcaccagaagcaactgcaacagcagcaacaacaacagcagcaacagcggaaCAACACGTCGAGCAGCTCGAGCAAATCGATGAAGCGAAAACGTGAACTGAAATGCGAATACTGCGCCTCCACATtcattagcaacaacaacctgCGACGCCACATGTACGAGCTGCACAAGCATGAAGTCAGCAATCTGCCAGAGCCGCCAGTCATTGAGGTGGATGAGCCGCTGACGTGCCGTCGTTGCGGCGATATACGCTTCGATACCAAAGAGCTGTGGATCGAGCATAAGCTGGCGGACGCCAAAGTGGTGCGTCCCTTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAGTACTTATCTCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAAGAGGATGTGATAGTGCCGGTGGCAGCAGCCAACAAGGCGGTGTTGCCAGTGCTGCCCAATAAGAATGCAACGGCAAAGAcaacagctggagcagcagcagcagcagcagcaggtggtacagcagcaacaacagcagtagcgACAGCCAAGGGAGGTATAGTTAGAGCGGCGGCACCAGCTGGCGGCAGAGCGAATAAGAGCAAACAGCAGCTGGAGGAGCAGCTGACCATGAAGGTGgcaacaaagcagcagcagcagcagcagcaggaacagcaacagcagcagcaagttgataatgatgataatgctGAGCAGGATGATGAGGAGGATGGCAGTGATatggatgatgatgatgatgaggatgataGCGATAGTGGCGATGGAGAGAGCACAAGTgcggatgatgatgatgaggacgatgatgacgatgaggGCGACGtggacgacgatgatgatgatgaagatgaagatgtgGATGGCGGTGTTGTTGAACAACAATTGctacagcaaaaacaacaacagcagcagcagcaggaacaacaacaacagcagcagcagcaacaacaacaacaacaacaacagaacctcaacagcaacagcgtgGCTGCCcacgatgatgacgacgatcTCATTGAGGAAGTCATCGAGGAGGATGGCATGGTCGAGGAGCTGGATGACGATGAGGACGATGAGGGTGATGACGATGGCAACACAACCGATGAGCATCAGCAGCTGGCAACCaatgccaagcagcagcagcagccgagacGCCTCAACTTTGACTATGCGAGCGCCGGCAGCGCCAAGCtgaatggcaatggcaaacaGACGCCGCAGCAGCTGGCCAAGTCGGAGGGACAATCGGGGGTGCTGGTAATGCATAGCTccgatgaggatgaggatgttggtgaggatgatgatgatgaggatggtGTGGAGGGTGAAGCGATGACCATTGATGATATTATTGAGGAAGATGATGGGgaggatgaggatgacgaTGTGGTTGGTGTCGATGGTGGTGTTGTTgaggacgacgatgatgatgatgatgatgatgatgatgatgttgggGAAGATATGGATgaggatgatgacgatgatgatgatgaggacgatgaggaagatgatgatgacgacgatggCGTCAATATTGGCAACAAAAATCGTCGTCGCGACGGTGCTGTGATGGTCAGCGGCATCAGCATTGGCGACGGTGAGGCTGATGCCGATGCTGATGGTGATGTGGATGGTGATGGTGATGGTGATGTGGATGCTGATGCTACATCATCATCGGGCAGCGAGTCAACAACATCGCATTCAATTGGTGAGCGGCGTAAAAAATCAGTAGTTAAATCAGTGGCACATGGCGCTGCCGTTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCAACTGCAGGCACATATTAAAAGCCATTTTCTGAATGGGCCGTCGGcgggtggcagcagcagcagcggcagcagcggcaacgccagcaacagcagaagaaTCGGTGCAGgggctggcagcagcagcagcagcagcggcggcggcggcggtggcgtcggcagcggcagcggtggcaacagcagcaggagcagcagcaatagcagtagcaccaacaacaataacaataataacaacaacaataataataataataacaaaagcaaaaccaaaaagtCCGGCTTGGATGCAGCGATTGGTGATAGttcggcagctgctgctgcaacagcatcaacaaccacaacaactacaacgacaacaagatcaacgacagcaacagttgccgctgcagcagctgcagcaacagcagctgctgacgCGGCAAACAGCTTGAACTGA
Protein Sequence: MVARCSATATTTTVALWTAPPATTSSSTSASSQQSLSTRCCCVCLITPLDRLSLHICHACISYLNSWQSFKNRCLSSQTKQRQWLDSDKSKQQTLLGYLDLNKTENGSAIEQQQQQQHESNIDSAMTAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQLQQLQQQQQQQQQQVQHAARATSAAAESQQTLQTLLLQVPSVAATSAQQQQQQQQQQRKYQQHQQQRVKQQHYQQQHHQSQQQQHQRLSRIRQPRRQQQATMSAQRMVRFKPKLYLPLDIAVPPLPPLLPTPTSTQQQQQPETVAAGAKLAPLPLPLSLPLDFSQSQCQHPNPNQSQQKHGNVLPLPLPLPPSTPLLPPLPAATMTSNAAATSAASATNAASASAAAAVTTPLLMPPLPAVPIKDEPIDETDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVAAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLTRDKVEFLQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRLKQPNFSHANASGVAVTADLSVGQAAAAAASAHETSSERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNYSIQCTFCGLDFADPVDRRRHYNNMECIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGISQSSNDESRSSTQHNNNNAVDAAFTSTPKPAGAAGGAATSAAAASAVSGGSTSGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSMPNVYTGRYDYVMKDLMSITNGGTLDDDEEETGSVAKKMRLDDSSNNSSINMSIANQQKECLICNAVFSNNIGLSNHMRSHYTAATATNAALAAANRMTPKSLTITATPPLETTATSTSAAATKASATAAAAVAATGTTSGAAVAGAGAATTGSGSLPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSIVYSSEMELQQHKRSVHKSHDAASSKSSTTKLSSATSASDLADTSGAGASAGVATGATAMPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPVECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQHQQQQQQRAIFKHKTGDDDDEEEDDQLMLLDDGGIGSDSNGGSNAPATATTSSSNNNPNTINASTLKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADVGQFKVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNLIIDGEATTLNNSSNNNNNNNSLSSSSMLRELHAVGLMPNQQQHQKQLQQQQQQQQQQRNNTSSSSSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDIRFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVAAANKAVLPVLPNKNATAKTTAGAAAAAAAGGTAATTAVATAKGGIVRAAAPAGGRANKSKQQLEEQLTMKVATKQQQQQQQEQQQQQQVDNDDNAEQDDEEDGSDMDDDDDEDDSDSGDGESTSADDDDEDDDDDEGDVDDDDDDEDEDVDGGVVEQQLLQQKQQQQQQQEQQQQQQQQQQQQQQQNLNSNSVAAHDDDDDLIEEVIEEDGMVEELDDDEDDEGDDDGNTTDEHQQLATNAKQQQQPRRLNFDYASAGSAKLNGNGKQTPQQLAKSEGQSGVLVMHSSDEDEDVGEDDDDEDGVEGEAMTIDDIIEEDDGEDEDDDVVGVDGGVVEDDDDDDDDDDDDVGEDMDEDDDDDDDEDDEEDDDDDDGVNIGNKNRRRDGAVMVSGISIGDGEADADADGDVDGDGDGDVDADATSSSGSESTTSHSIGERRKKSVVKSVAHGAAVDQSNSSYTCDLCQLCFDSQEQLQAHIKSHFLNGPSAGGSSSSGSSGNASNSRRIGAGAGSSSSSSGGGGGGVGSGSGGNSSRSSSNSSSTNNNNNNNNNNNNNNNKSKTKKSGLDAAIGDSSAAAAATASTTTTTTTTTRSTTATVAAAAAAATAAADAANSLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00476771;
90% Identity: iTF_00599728;
80% Identity: -