Dsor011363.1
Basic Information
- Insect
- Drosophila sordidapex
- Gene Symbol
- sba
- Assembly
- GCA_035043295.1
- Location
- JAWNNA010000914.1:4960768-4968105[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 0.44 9.1e+02 -0.4 0.0 29 57 142 171 125 212 0.78 2 2 7.1e-09 1.5e-05 24.6 0.0 9 58 244 284 236 305 0.81
Sequence Information
- Coding Sequence
- ATGGCTGCCGCATCCGCtggccaacagctgcagcagcagcagcagcaacaacagactCAGCACAAATTGAacattgttggtgttggcaaTGCGGAGACGGTTGCTGGTGTGCTGCAGGTCAACAAtgagttgcaacagcaacagcaacagctcaacatgtacaagcaacagcagcaacaacaattgttgcagcaacagcaacatcaattcTATCAGCAGCAAACGAAATTTGTATCGCGGGTCGTTACAAATGCAGCCGCaatgcaaccacaacaacaacaacaacagcaacaaatattacCAGCTGGTTTGGTAAATGGCAGCGCCAACATGATGCAAGCCACAAATGTTGCtgtacagcagcagcagcagcaccaacaacagcagcagcagcaacaacaacagcagcaacaacaacagctgcgtCAAAGTCaacacatttttgtgtgtcCATCAATAGGCAcgcagctacagcaacaacagcagcagcagcaacttcaacagcagcagcagcagcagcaaagcaaacagcGTTTAGCGCAAATCAAGTTGCCTGTAAagtctgcagcagcagtcgcaacagcaactgttgctgccgcaCACTGTatgccagcaacaattgcaatgcgTCAAATGAATCAGaaccatcagcaacagcagctctaTGCTAAGAATgtggccaaaaacaataatgctggcaacaacatcaacagcaacagcaacaacaatgcaaatttggcTCCAGGCTGGCGTCGactaaccaacaacaatgaagtGGCCTACATCAGTCCAACGGGCAAAACGCTGCGTACACAATTCCAAATTAAGGACTATTTGCTAACACAGGGTACCTGCAAGTGCGGCCTGCCGTGTCCGCTGAGGCCGGAATactttttcgattttaatgCACAGGTAAGTTAG
- Protein Sequence
- MAAASAGQQLQQQQQQQQTQHKLNIVGVGNAETVAGVLQVNNELQQQQQQLNMYKQQQQQQLLQQQQHQFYQQQTKFVSRVVTNAAAMQPQQQQQQQQILPAGLVNGSANMMQATNVAVQQQQQHQQQQQQQQQQQQQQQLRQSQHIFVCPSIGTQLQQQQQQQQLQQQQQQQQSKQRLAQIKLPVKSAAAVATATVAAAHCMPATIAMRQMNQNHQQQQLYAKNVAKNNNAGNNINSNSNNNANLAPGWRRLTNNNEVAYISPTGKTLRTQFQIKDYLLTQGTCKCGLPCPLRPEYFFDFNAQVS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00513461;
- 90% Identity
- iTF_00528044;
- 80% Identity
- -