Dsil009668.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila silvestris
Gene Symbol
zfh1
Assembly
GCA_035043445.1
Location
JAWNMZ010000148.1:7024813-7031016[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 2.8e-05 0.0019 18.5 1.0 1 23 152 174 152 174 0.97
2 15 0.00086 0.057 13.9 1.2 3 23 182 202 180 202 0.94
3 15 9.4e-05 0.0062 16.9 0.1 1 23 371 393 371 393 0.98
4 15 0.00032 0.021 15.2 0.9 1 23 399 421 399 421 0.98
5 15 8.1e-05 0.0053 17.1 2.1 1 23 453 476 453 476 0.95
6 15 0.74 49 4.6 4.3 1 23 517 539 517 539 0.87
7 15 0.0042 0.27 11.7 0.4 1 23 545 568 545 568 0.98
8 15 0.027 1.8 9.1 0.4 3 19 577 593 576 594 0.95
9 15 0.00016 0.011 16.1 5.6 1 23 603 625 603 625 0.97
10 15 0.042 2.8 8.5 1.2 2 23 631 652 630 652 0.96
11 15 9.6e-06 0.00063 20.0 1.0 1 23 661 683 661 683 0.98
12 15 0.0011 0.072 13.5 0.1 3 23 691 711 689 711 0.97
13 15 5.8e-05 0.0038 17.5 0.5 1 23 717 739 717 740 0.95
14 15 0.049 3.2 8.3 0.4 1 23 750 772 750 772 0.97
15 15 0.00052 0.034 14.5 0.8 1 23 1280 1302 1280 1302 0.98

Sequence Information

Coding Sequence
ATGAACAATCCGAACTATGGCGGCATCCAGTGGATACAGCAGGAAAGCAGCGCCGTCGTCGACGACAGCGAATCAGAGATGACAGCAGCATATTTGGTCAACGCTGACGCCAATGGAAGCATTTCCAACGATGACGATCTCGATCATATGGCAGCCGAGAatcttatttttatggcaCGCGACGGCCAACTGAGCGAAATCATCGCCGCCAATGAGGCAaatggcggcagcagcacagTGCTAATCACGGAGAGCGACGGAAATAACGGTGTCGAGTACGCCGAGTCCTTTGACGATGATGCCCAAGTCGTCACCGAGGAGATCATCACGGATGATTGGGTCCAGCATCAGGGTGCAGAGCGagTGGAAATTGCCGCTGAGCAAATCGCTGGCACCGGCAGCTCCCAGGAACTGTTGGACATGCAACAGAATGAGTATATGGCGATGCGTCCCTATCCTTGCGACTTTTGCAGTCGACGGTTTCGGAAGAAGGCCAGCCTCAACAATCATATGCTGGCGCATCAGAATGATCGGCCCCATCTCTGCAAGCTGTGCGGGGCGCGTTTCTCGCGTCGCGCGGAGCTCATCAGTCACTTCAAGGCGCATGCGGAGGCCCAGGTGGCCGCCGATGAAGAGGCAGCTGCGGCAGCCATCAAATTtgagccacaacagcagctgcaacaacagcagcagcagcgacaaattGAGGATCATTTCTATGAGCAGGAATGGCCGCTGTatcaggaacaggaacaggagcaggagcaggtcgaggagcagctggagcagatcgaggagcagcagctattGCAACACTTGGTGGCACCACCAACCGCTGCCAGGGGACGCATCAGTCGCTTAAAGCTCAAGGAGGAGAGTTCGCAGTATATTGTGATTGCCTCCGATAAACAGGAggcggagacggagacggagttGCCTCAATACATGCATTGCGAGGCGAATTGCGACCAATCACatgccaccaacaacaatcaactCCAATCAACATCCAACAATgatgttgcaactgctgctgctgctgatgaggCACATGGGCAGGGACATGGGCAGGCAACGCTGCGTTTTCCCGTGCTCGACGAGAGCAAACCCTTCGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCGCTCGTCTCCCACATCAAGAATCATCGGGTGGATTCGCCGTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAACTACAGTCTGCAGGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAACTCGGAATATGATCCGGCATCGGCGGGCGAGGAGGATACGGCGAGCGAATCGGAAGCGGAACAGCTTTACGGCAATTACTACTGCGGCGAATGCGGCATCTCCTTTCACCGGCAGGATTTGCTGCGGCgccacagcaaacagcagcacagcaagcagctggctgcaacaacagctggtaacaacaacaacagtgtggcaactgcaacagcaacggatgcagctgcagctgcaactgatgCCGAAGCTGATGATGCCAAAGATGCGCCACATTGTTGCCACACGTGCGGCAAATCATTTCTCAGCGTACTCAAACTGCTCGCGCATACCGAAATCCACAAACGCTTCCCGCCATTCAAATGTGTGCTGTGCGGCGTCAGTTTCTACGAGGAGCAGGCCATTAAGCGGCACCTGAACACGCGGCATCCGCATGAGCTGAAGCCCAAttcgtgtgtgttgtgtggcaAGGAGTGTCGAGATCGGAAGGCGCTGATCAAACATGCCTGGGATCATTCACGGGAGAAGTGCCACTCGTGCTCCAAGTGTGGCAAGAATTTCCACAACAAGGCGCGGCTGAAACGACACATGGCATCGCATCGCGACAAGTCCGTCGTGTGCGAAGTGTGCCACGAGGAGTTCCCAGATGGACGCACCTTGTCCAATCATCGGCATTCCCACAGCACAACGTCGCCGGGCAAACTGTTTCCCTGCCACGAGTGTGGCAAGACTTTTGGGTCGCGCAGCTCGCAACAGATTCATGTGCGCATCCATACGGGTGAGAGGCCCTACGGTTGTCGCTACTGCTGGAAGGCCTTCGCCGATGGCGGCACTCTCCGCAAACACGAGCGCATCCACACGGGCGAGAAGCCCTATGCCTGCTCCGTCTGTCCGCGTGCCTTCAATCAGCGTGTCGTGTTGCGGGAACACATCCGGTCGCATCATTCCGGTCTGGATGCGGCACGCGGCACGTATCATTGCACGGTCTGCTCCGCGGATTTGAGCTCATCGAATGACCTCATCCAGCATCTCATCCAGCACAGTGATACGAACACAGCCAAACAGCGACAGCCAATTACTGGTCCACGTAAATATAAACGTCGCCGGAAACTGCAGCCGCATGAGATTGCGCACATGCGCGCAGAGCACAAGGCTGGCGGTGGCGAAGGCGAGGATGAGGATTATGGCAGCGACTTGGACTACTGCGATCTGGATGTGGAGAATGTGGATGAACTGCTGCAGGAAGCAACCGCagagccaccaccaccagccaCCAAAAAAGCGAAACGCAAACGCAAGGCGCCAATTAAAACCGGCGATGAGCAAAGATTGTGGGATGAGAAATTCCTGCAGCAGGCGAGCAATGGGAACAGCGATGAGGCCTACAAGAGTTTCTTTCAAATGGACTCGCTGGTCGTGGTCAATGACCAAACGTTGCAGCCCGTTGATGCTGGTGTTGCCACGACCAAGTTGCAGCAGGCGGAGATTAAGGAGCAAAAACTCAAAACAGGCAatcgcagcagcaaaagaaggGCAGGCAAATCTGGgggaggagcagcaggaggaacAGCAGGAGTAGTagaagctgttgctgctccacgTCCCCGCATGATACACACGGCCAAGTCGCAGCAGACAACGTCAAGGAAGTCCCGCACAAGGAGTTATGTCACACGCACCAGCACCaatgagcagctgcagcagcagcagcagccaggagGAGGAGCAAGCCTCATCAAATCGCGCATTGTGGATGACTACGAGATCATCTCACCGGCCACACAGCCACCCAATCAGATCAGCTCCAGTCCGCTGCACATCAAACAGGAGCAGgaacatcaacagcatcatcagcaacagcagcaccagcaccagcagcagcaccagcgaGTCCAACTGCTCTTCGATGACAGCCATCTGCTCATCGATGCGGGCCTGTTGCGTGAGAAGACCTACGAGAAATATAATCCGAGCATTGTCCAAGATCTCGAGGAGATATTGCGTAGTCCCCCCAAGCATGAGCGAAACGATCGACGGCTGCGCTTCACCAGCGAATCGTCGACGACGCCACAATTTCTGCCCGGCGAGGAGGAGGAACAGCATCTCATCAAGATCGAGCCAACGTCGCCGGATCTACGCGAAATGGTCGAgagccagcagccagccacaCTGCCCACATCCTCCTCCGCCGCCTGCTCAACGGCGGCACGCACTTCCCGCCACCTGCGACAGCTGACTGCCAATGGTTCCAGTTCCATTTCCACTGCCACTTCCAGTTCCAGTGCCGCTGGCAGCACGCGAGCCGCTGCCAAGCGCAATGCCAGCAAGCAGCTTGCTAAGAAATCCACTTCCAATAGCAGCAAAGCCAACTCATCATCGTCTTATCTCAGCTATGGCGTCGACTCCTATAATGTGGGCGTGTCAGCCAGTGCCAATGGCTCGTCGGATGTCAGTTCCGgtttcttttccatttccgAGGTCGTCTCGGCAGCGGATGCAGCCGATGCAGCTGCgaaggcggcggcggcagcagccagcaaaacgGAGCGAAGAACGCGCTGCTTTGAGTGCGAAATGTGCTCGTCCAATTTTCCAGATCGCTCACAGCTGCTGgaacacatgcacatacacatctAG
Protein Sequence
MNNPNYGGIQWIQQESSAVVDDSESEMTAAYLVNADANGSISNDDDLDHMAAENLIFMARDGQLSEIIAANEANGGSSTVLITESDGNNGVEYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGTGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQVAADEEAAAAAIKFEPQQQLQQQQQQRQIEDHFYEQEWPLYQEQEQEQEQVEEQLEQIEEQQLLQHLVAPPTAARGRISRLKLKEESSQYIVIASDKQEAETETELPQYMHCEANCDQSHATNNNQLQSTSNNDVATAAAADEAHGQGHGQATLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGEEDTASESEAEQLYGNYYCGECGISFHRQDLLRRHSKQQHSKQLAATTAGNNNNSVATATATDAAAAATDAEADDAKDAPHCCHTCGKSFLSVLKLLAHTEIHKRFPPFKCVLCGVSFYEEQAIKRHLNTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAARGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKAGGGEGEDEDYGSDLDYCDLDVENVDELLQEATAEPPPPATKKAKRKRKAPIKTGDEQRLWDEKFLQQASNGNSDEAYKSFFQMDSLVVVNDQTLQPVDAGVATTKLQQAEIKEQKLKTGNRSSKRRAGKSGGGAAGGTAGVVEAVAAPRPRMIHTAKSQQTTSRKSRTRSYVTRTSTNEQLQQQQQPGGGASLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHHQQQQHQHQQQHQRVQLLFDDSHLLIDAGLLREKTYEKYNPSIVQDLEEILRSPPKHERNDRRLRFTSESSTTPQFLPGEEEEQHLIKIEPTSPDLREMVESQQPATLPTSSSAACSTAARTSRHLRQLTANGSSSISTATSSSSAAGSTRAAAKRNASKQLAKKSTSNSSKANSSSSYLSYGVDSYNVGVSASANGSSDVSSGFFSISEVVSAADAADAAAKAAAAAASKTERRTRCFECEMCSSNFPDRSQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00542584;
90% Identity
iTF_00499722;
80% Identity
-