Basic Information

Insect: Drosophila silvestris
Gene Symbol: rfx7.L
Assembly: GCA_035043445.1
Location: JAWNMZ010000151.1:22499108-22503672[-]

Transcription Factor Domain

TF Family: RFX
Domain: RFX domain
PFAM: PF02257
TF Group: Basic Domians group
Description: RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2e-32 1.7e-28 99.0 0.1 3 78 309 384 307 385 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2e-32	1.7e-28	99.0	0.1	3	78	309	384	307	385	0.97

Sequence Information

Coding Sequence: ATGTCCGAGAAGCATGGCCAACTCAGTGGTGCGCAGTGGACGAcgaaatcagcagcagcagtggggGGCACAACGGCAACTACGCTGCAgaagcatcagcaacaaacCAATCCAAATTCCAATCCGATATACGAGGCAACAACAtcagttgcacacacaaatccGTATGGCGCTTGTGTTGTTCCGCTACCGGTGCCGATTCAGATTCCGGACATTCCCTCGTATACATCGGGACGTTTCCAGGCACCGCCCATTCATTTGCAAATGGCGAAATTATCACCACTAACCATTGCGCCAATTGTGGCGCCTGCCCAGCAACTCGCCCAGTCCCAGGTGTCGCCCACATCCACAAATGTACCTGCTCCCAGCCAAAGCGGCTTTGTGTCGCCAgcttttacaaatttgaatgccCCTGGCTCGGTAGCCAGTGGAGTCACATCCGTGCTCACTCCGAATCCCTTTGCAGCGGCCTCTGGCAATGCTGGTTTGGCCTTTGTCAATGCCTTTAAGGGCTCTCAGCAATTGGATCTGGGAAAGATAATGCAAGCGATAAATGTTAATGCCTCTacagcgtcagcagcagcgttgccgAGGCACCCACATCCGCCAACTCCCCATCCCAGTGAAGGCGGCTTAGTAGCTGTAGCCGCCGCTCCACCCAGTGGCATCATCAACTCCACAATTGCGGAGAACGTAATGAATGCGCTGACCAGCGACGAAGAGCGAATGCGACGCGTCCAGCAGGTCATCGAGTCCAGTTTGGATGACACTGCCAAGCTGCAAATTGCGCAAATTCTGGAAAATGTGGCAGGCTTGAAGCCCATTGAGAAACTGTTTCTTTATTTACGATTACCGGGCGAGACTTCGGACACTGACCCATTGAGACAGCCACAGAATCCGTTGGGTACACGCTCAGAGATTAATCATACCATTAATTGGGTGCGCTCGCACCTCGAGCACGATGCTCAGGTCTCCATACCAAAACAGGACGTTTACAATGATTACATCGTCTATTGCGAGCGCCTGAACATCAAGCCGCTGTCAACGGCTGATTTTGGCAAGGTAATGAAGCAGGTGTTTCCCGGCGTTCGACCGCGACGTTTGGGTACGCGCGGCAATTCGCGTTACTGCTATGCGGCCATGCGGAAGACCACAAAATTGACGCCGCCACAGTTGCCGCAATTGTGCAAGGATGAGCCAATCGATGACAGTGCGCCCACTGAAACCTCCCCAGCACATTTAAAGCGCACACCCAACGCCCCGGGAAGCATACCAGGCGCAGATGACGATGGCAGCTGGGATGTGGTGCGCAGTTGGGCGGAAAAACTACTCAACACTAAAGTGGACAGCGTCACAGAGTTAGCCACACGCATTAAAAGCAACAATGCAGCTATTAATCCAGTAGTGGCGGCCAAGAAATATACGCCCAGGGAGCCCAAAGAGAAGCGCTTGCTTGCGgACATGGGACCGCTAAAGAAGCGCCGCAAAAAGAAGCGCAAGGGCTCCACATCCTCCGAATCGAGCTGCAATCAGCCAAATGCCGCCACCGATGCTGGCAGCAGTCAGGAGGCGGTCAGCGATGACCACAAAACGGAACAGTTACTACAGATCAAACAGGAGATTATAGACTCGCCCAGTAGCTATCCGACAGCCCCACAgcttcagcaacagcagcagcagcatcagcaagtTTTGCCTATGAATCTGGCCACGGAGCCGCGTAGCAATGCTGTCCGTAATCTAACGCCGAAGCTAATAGAGTTGCAAACGGAAGCGGCGGCACAGCAGCCGATGTCACCCACTGGGCTGGTCATCAAGGACGAGGCCGAAGAGTACAACACCACAAACATATTCTGCAAAAAAGTGCTTAAGGCGCAACAGACCAAAGGCAATTGGGTCAACTCGCCCAGCAGCGGTGGCGGTAGCGGTGGCGCAAGCGGCAGTACTATGCTTATACCACCAGTGATAACCACAACGGCGGCAACACCTCCACCACCCGCTCAGCCACCACCAGACAGCTCGCCGGTAAATGTCACAGCGCTATCAATGGGCCCGCCCGCCCAATTGAATAATCCCAGCTCAGTAAGTCCGTCAAGCAGTCTGGAgacgaacaacagcaaccccAAGGTCTCGACGCGCAACATGATTTTGATGCGGACGAGACGCTTGGTGGCCGAGAATGCGGCGGCATTTGCCGCTGCCGAGGACTCTGGGCTGCCTGAGAATCTGGGGCTGCCGCGGGAGCGCGTCATTAGCATATGCAATATGGATAAGCATGAGCTGGATGATTACTTTCTGCCCGGCGACGATGAGGAGGAGAATTCCGAGGGGCAGGATACCGAGTTGCTTCAATATTTTCAGATGGGAGACGCTGAGGAAAAACAACTGAATTCCTTAGATGCTCATGCAGAACAACACAGAAATCCACAGGCTGCGTCAGCTAATGCACTAGCCaatgcaatggcaatggcaaatgctagaacagcaacggcaacagcaacaacaacagcagcagcgatgcaacagcaacatcagcagcagcagcagcaacaacaacagcaacagttgcagctgcaacacatGCGTCGCTCAATGCCgttgccaacagcagctgcagtagcagcagcagcagcagcagcgacagcagcaacaaatgttgtgGGTTCTGCCTCAGCGTCTCTGGCTTTAATGTCACGaaagcatcaacaacaacaacagcaacaacatcagctacaacaacaacagcagcagcagctgcgatatagcaataacaacaacaacaacagcaacaaacgcaAGATTAGTTTAAGCAACGCGtccagcaatggcaacaacaagaactgcaTTTTTCTGCCTATTTCCCCAaacaacgcagcagcagcaacaacagtggcaGAAACTGCAACATCAATAGTAGCTGCaaccacatcaacaacaacaacaacagctggaaAGCTGCCCACTCAGAATTGCTTTGCCAGTCCTGGACTCACACGAATGCGACAACGTTCCAGTATGCTAACCAAACAGCAATCGCTGGACTTTGACAACAATAACGGCAATGGTGACCCAATGATTGGGGCGCATCGGCGCAGGCGCAGTTATGTGTACAGTTatcccagcagcagctccgCCTCGGCTCCGCCAAGTCCCTCGCTATTGCAACAATGTATGGGCGTCAATTGGTCGTTTAGCGGCAGCGCTGCTAACAACAACCAGTTCAGCGAGAGCActacaaacaacagcagcaacaacaatgtggaGCTGCTAATCAATCAAAACTCTATGGATTTGGAGACTAGTCTGGCTCTAAGCGGCGCCAGTATCGAGCTTAACGAAACACAACGTTCACAATCTGTGCCACTGTCGCAACTGCaacgcggcagcagcaaccactcACCCTCAACGGGCTACAATCGTCAGCTAAATCAGGCGGTTGTCAACGCTTGCATTGTCCACGATGCGTTCTTCTCcgagaacagcaacagtcagCAGTCTGTGGGCGCACTGAAACTGGGCGCCAACGATGTTGATGTACCGGCTAGTCTGATCTACGACGATGTGGACGTCAGTGCGCTCATTTCGCCCAGTTTTGCTAACAAGTTTAGCGGCATACAAACAACGACCACATGCAGCTCATCGGCGGGCTCCTCGAGCGGTTACAGCAGCGCTGGCAGTGCTGGCGGTATAGTGTCGCGATCGGTGCCCTCCACACCGCTACCACATCAGCAGTCGCAGCTGCAGGGCTACAACAGTGGTCAGAACACCGCaaacggcaactgcaacgaCGCCAACGGGCTATTCAACATCTCGCCAGCCTTCAAttggggcagcagcagtgtgTCATACAATGGGCAGCCGTATGGTTCGCGAACAGCTCTCGATATATCCAAATCGATGCCAACGACGCCTATAACGACTCCGTGTTTTCGCTACAGTCCCGTCGAGCTGCATCGCGACTTTCTAATCAATGGTAATACGATTGATAGCCTGCCGTCGCCGGCTGTGGTGCCTTTCGGCGTTGGCAGTGCCACAAACGCCGTTTTGGCACTCAGCAGCGATGCGCTGATTGATGATGTGGCACCAAACAGCAGCGATGTGGATGCCATAATTGGTGCCGCCAATATACTCGATAGCTTGTAG
Protein Sequence: MSEKHGQLSGAQWTTKSAAAVGGTTATTLQKHQQQTNPNSNPIYEATTSVAHTNPYGACVVPLPVPIQIPDIPSYTSGRFQAPPIHLQMAKLSPLTIAPIVAPAQQLAQSQVSPTSTNVPAPSQSGFVSPAFTNLNAPGSVASGVTSVLTPNPFAAASGNAGLAFVNAFKGSQQLDLGKIMQAINVNASTASAAALPRHPHPPTPHPSEGGLVAVAAAPPSGIINSTIAENVMNALTSDEERMRRVQQVIESSLDDTAKLQIAQILENVAGLKPIEKLFLYLRLPGETSDTDPLRQPQNPLGTRSEINHTINWVRSHLEHDAQVSIPKQDVYNDYIVYCERLNIKPLSTADFGKVMKQVFPGVRPRRLGTRGNSRYCYAAMRKTTKLTPPQLPQLCKDEPIDDSAPTETSPAHLKRTPNAPGSIPGADDDGSWDVVRSWAEKLLNTKVDSVTELATRIKSNNAAINPVVAAKKYTPREPKEKRLLADMGPLKKRRKKKRKGSTSSESSCNQPNAATDAGSSQEAVSDDHKTEQLLQIKQEIIDSPSSYPTAPQLQQQQQQHQQVLPMNLATEPRSNAVRNLTPKLIELQTEAAAQQPMSPTGLVIKDEAEEYNTTNIFCKKVLKAQQTKGNWVNSPSSGGGSGGASGSTMLIPPVITTTAATPPPPAQPPPDSSPVNVTALSMGPPAQLNNPSSVSPSSSLETNNSNPKVSTRNMILMRTRRLVAENAAAFAAAEDSGLPENLGLPRERVISICNMDKHELDDYFLPGDDEEENSEGQDTELLQYFQMGDAEEKQLNSLDAHAEQHRNPQAASANALANAMAMANARTATATATTTAAAMQQQHQQQQQQQQQQQLQLQHMRRSMPLPTAAAVAAAAAAATAATNVVGSASASLALMSRKHQQQQQQQHQLQQQQQQQLRYSNNNNNNSNKRKISLSNASSNGNNKNCIFLPISPNNAAAATTVAETATSIVAATTSTTTTTAGKLPTQNCFASPGLTRMRQRSSMLTKQQSLDFDNNNGNGDPMIGAHRRRRSYVYSYPSSSSASAPPSPSLLQQCMGVNWSFSGSAANNNQFSESTTNNSSNNNVELLINQNSMDLETSLALSGASIELNETQRSQSVPLSQLQRGSSNHSPSTGYNRQLNQAVVNACIVHDAFFSENSNSQQSVGALKLGANDVDVPASLIYDDVDVSALISPSFANKFSGIQTTTTCSSSAGSSSGYSSAGSAGGIVSRSVPSTPLPHQQSQLQGYNSGQNTANGNCNDANGLFNISPAFNWGSSSVSYNGQPYGSRTALDISKSMPTTPITTPCFRYSPVELHRDFLINGNTIDSLPSPAVVPFGVGSATNAVLALSSDALIDDVAPNSSDVDAIIGAANILDSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01321657;
90% Identity: iTF_00542180; iTF_00576808; iTF_00518186; iTF_00566530; iTF_00497124; iTF_00485603; iTF_00570140; iTF_00494851; iTF_00548545; iTF_00521090; iTF_00592834; iTF_00497891; iTF_00499331; iTF_00527786; iTF_00597099; iTF_00496333; iTF_00521902; iTF_00552047; iTF_00516734; iTF_00558398; iTF_00573786; iTF_00619582; iTF_00511013; iTF_00564394; iTF_00501546; iTF_00500045; iTF_00535055; iTF_00498609; iTF_00582703; iTF_00513201; iTF_00615941; iTF_00481972; iTF_00609620; iTF_00576087; iTF_00543483; iTF_00524863; iTF_00559967;
80% Identity: -