Basic Information

Insect: Drosophila sechellia
Gene Symbol: -
Assembly: GCA_004382195.1
Location: NC:9968110-9977748[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0088 0.55 10.4 0.3 1 23 1257 1280 1257 1280 0.95

2 13 6.2 3.9e+02 1.5 0.2 1 23 1427 1449 1427 1449 0.91

3 13 0.00014 0.0088 16.1 2.7 2 23 1452 1473 1452 1473 0.97

4 13 5.4e-05 0.0034 17.4 0.2 3 23 1481 1501 1479 1501 0.98

5 13 4.5e-07 2.8e-05 23.9 4.1 2 23 1508 1529 1507 1529 0.97

6 13 4.2 2.7e+02 2.0 0.4 5 23 1542 1560 1540 1560 0.96

7 13 1.1 66 3.9 5.4 3 23 1567 1588 1565 1588 0.93

8 13 0.11 7.1 7.0 0.2 2 23 1599 1619 1598 1619 0.96

9 13 0.00011 0.0072 16.4 0.3 1 19 1625 1643 1625 1647 0.95

10 13 2.7e-05 0.0017 18.3 0.4 1 23 1655 1677 1655 1677 0.98

11 13 8e-05 0.0051 16.8 7.6 1 23 1683 1705 1683 1706 0.96

12 13 0.00017 0.011 15.8 6.5 1 23 1711 1733 1711 1733 0.98

13 13 0.0021 0.13 12.4 6.1 1 23 1739 1761 1739 1762 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0088	0.55	10.4	0.3	1	23	1257	1280	1257	1280	0.95
2	13	6.2	3.9e+02	1.5	0.2	1	23	1427	1449	1427	1449	0.91
3	13	0.00014	0.0088	16.1	2.7	2	23	1452	1473	1452	1473	0.97
4	13	5.4e-05	0.0034	17.4	0.2	3	23	1481	1501	1479	1501	0.98
5	13	4.5e-07	2.8e-05	23.9	4.1	2	23	1508	1529	1507	1529	0.97
6	13	4.2	2.7e+02	2.0	0.4	5	23	1542	1560	1540	1560	0.96
7	13	1.1	66	3.9	5.4	3	23	1567	1588	1565	1588	0.93
8	13	0.11	7.1	7.0	0.2	2	23	1599	1619	1598	1619	0.96
9	13	0.00011	0.0072	16.4	0.3	1	19	1625	1643	1625	1647	0.95
10	13	2.7e-05	0.0017	18.3	0.4	1	23	1655	1677	1655	1677	0.98
11	13	8e-05	0.0051	16.8	7.6	1	23	1683	1705	1683	1706	0.96
12	13	0.00017	0.011	15.8	6.5	1	23	1711	1733	1711	1733	0.98
13	13	0.0021	0.13	12.4	6.1	1	23	1739	1761	1739	1762	0.96

Sequence Information

Coding Sequence: ATGGTCGACAACAGTGTCCAATGCCCCGTGTGCACATTGTACCTGCATGCGGGCATGAATCTCTCCGATCACTTGGAGACCCATCCCAAGGAGCAGGTGATCAAGGCGCTGGTGCAGATGACGATCGTTGGGAACGGTGGCAACAGCATGGGCAGCGTTCTCGCTGCCGCCATGCTGACAGGAGGAACTGGAGGAGGTGGATCCAGCGGCGGCGAAGCCAGTGCTGATGAGAAACCGGCCGTCTTATCACCACCGTCTGGCGGCGATGTCAAACCAGTCGTGGCCAATACCatatcagcagcaacagcgccTGTGCtgccaccagcaccaccaccgctATCCTCCTCCCTCGTGGCGGCCTGCTCCAACGGAGCCGCCTCTTCGACAACCAGCTCCGCACCCACCTCCACTTCAgcaagcaacagcagcagcaaaccgAGCAATCCACCGATGAAAGCACTGAAATGCTCACCGCCCACAACTGAGGCGCGAGCCAGCACATCCGCACATCCCACCACGAGCAGCGTGTCCACTTTGTACCAGCCAGCGCAGGTCACTCCGGATTACCGCTTcaaccagcagcagccacagacGACGGGCTTTGGGCGTGGTGTCACCACCTCAGCAGCCGGTCTGGTGATTCCGCAGGTGCCTCAGCAGCACTTCCTCGCCAGCCATCAACAGCAGGCTCACTTTCCACACCAGCAGCAGCccccgcagcaacagcagcagcatcagcctGCTCTGAAGTTCAGCTACGCCACAGCTTTGCCCCCACCTCCGCCGTTGCAGCTATTTACccagcaccagcaacagcagacgGTTGTTCCACCGCAGACCCAGCAGCAATCGCACCAGAAACCACCTCCCGCCTATGGAGCCGCCATTAGTCAAATACGATCTCAGCACaaccaaaacaaacagcagcCACAGTCCCAAAGCGTGGCTATGCAACACAGCCTAGCCCTGGCACCAACGACGACATCAGCGGCTTCAACTTCACACGCAACTGCAACTGTCAAGCAGACCAGTAAACCGCAAACGGAAGTATTCCTGAATCCCCCACCACCGCCATCGGCACAGCAACAGTTGCAGATCCACAATTTAGTGCAAACTCAAGGTCAACACCATCAGCATCCtcaccagcagcagtcgcagccGAGCCAGCAGAGTCACCAACAGCCACCGAGCTTGCAGACCTACGGATTGGGGGTCAGCAGTAGCTGCAGTTCCTCCAACAACCCCTCGACCTCGGGATCTGGTCATCGTGCGAATCGTCAGACAAACTCACCGTTTGGAGCACTGCTAAATGCTGCAGCGGCTGTGGCCTGCGCATCGCCGGCCTGTCCCACCACCGCATCTTCGGTATTGAGGTTTGCAGAATCACCGGTGGCACACTACCTTGAGCGGGAAAATGGTGACTTCATTGTCCAGGAGACACCGAAGCATATCGTAGAGTGTGTGGAGAAGGAAGACGGCGAGTTTTCCGTGATCGAGCGCATTTATCAATCCCCGCCGAGTGTTCTGCACATacacgatgatgatgaggatgaCGAGGATGAAGAGGAGGAGCACGAGCATGAAGCTCCGCCCGAGGAAGAAGACGGGGACGATGAGCGGGAGGAGAACAGCCACAGCCGTAATATGAGCAAGACAACGAAAAAGGCCCGTAAGACGAAGCCGAAGCGCGGCTCCAAGCGCATGTCGGACGAGGAGGAGTTCATGAGCCTGAGCAGCGGATGTGAGAGTGAGTTGGAAAAAGAGCATAAGCAGGAGCAGCTAAATGCAGCGGCATCACTACCACCTCCATTGTGCACGGCTCCTTCAAcgagtgctgctgctggagcttCCACCTCCAATCTGGCGGACAATCATTCCAATTCCGCGTCCAACTCCGCCTCCAATTCGAACTCCACCGCCACTACAAAGTCCAAGAAGAATCGGATTACCGTACTCAGCGATGTTCCGCTCAATATGAATGAGTACCTCGATTTGATGGGCAACATCGTAGCCTCCAGTCGCATTGGGGCAAGTCGACCGTTTGCCGCTGTGGCTCCCATACCACTCGTCAAAGTGGAAAAGGAAGAACCCCTGGATGATTACGACAACGTGGCAATGGCCGCTAATGCCGAGCTGGAGCAAAAGCCCAGCCTTGAGCACGGCACCACCAGCGTCATTCGAATGGCAAGCACGGCTGCAGCGTCGACTTCTGCAACGGCGACCGAAACGTCTCCCGAGGATCTCACCCAGCCGCCGCCCATGAAAGTCGAGGTTGAGGCGACCACCACATTGTTGCCGCAGCGCTTTTCAACTCCCGCCCAGCATCGTGGGCCTAAGAAATTAGTCAtcaaaccaaaacaaacagcaCCAGCGACAGCGACGACAACAAAAAAGACTGACACCCCATCTTCCCCCAGCAACAACCCATCCATATCAAGAGATCTGGTGCAAGTAAAGAGTGAGACCCTAGAGGCACCAGCGACGAGCAGTAGCATTCTGGAGAAGCACCTAACCGCCAGCCGAAAACTATTGCATCATCACTCGGCGGTGAACGATGACGATGCCCGGGTGCTGCTGGAGTTTGCAAACTCGAAGCAGCCGCCGCCACTGGCAGCGTCGAGCACAACGTTCGTGGTCAATGCCAGTGTAGGCTTTCCCTCTGCTGGCTCAGTTTTtgccagcagcagtagcagctgTTCCAAAGCACCGGCCAAGCCGGGAGAAGAGTACATCCTGCCGGACAACAACATGGACGTGGATGAGATTGTGATATCCTCGTCGTCTTCCTACACCTCCACCGCAGCCCAGGTGCAGAACACGTTACAGCCGCCGGACTTTAACTTTCTGTACCACCAGGCCACTACCACTGCTACGACGGCCACATACTTTAATCCCTTCTCCaggcagcagcatcatcatcagcagcagcacggCGTCAGCGATGCCACCAATGCGGCCACTTTGGCTTCGTCGTCCAGCAATTCGTTGGACCACGACTCGATGAATGCTACATTCCGGGTGGCCAAGACCCAATCGCTGCAGTCATGGTATCAGCAAGAGCCGGATCACGATCCACAGAATCAGGGTGGTGCGGAATCGGGAACTGCCACACCCTCCAATCAGAGCCAGGATGTGGTCAGCCACCAGCCAACCAACTTTAACGCCGCCCTAGCGGCCGTCGATTGCTGTAGCGTTGCTTTGGACGAGGATGCAAAATATCTTGATCTAGACGCCTGCAAGCGGGAGCAGCTGAGCAGCAGTAGCAACCTGCCATCCGCTTCCGCGTCCACAACGTCGTCGTCGTTCGCTGGCGATGGCACGGAAAGCAGTTTGGTGGGTGGCCTGAATATCCGAACCGATGAGAAGATGCCCGCCAAAGGTGAAATCTCCGAACAGGAAAGCAACTGCGACATCGAGAACTCCTGGAGTGAGTCGGTGTATGGGGATATTTCGCAGCGGTACTTCAGAAACCAGTTTTCCGGCGGCTACAACCCTGATTGGCGACAGGACTATTATCCGGCTCAGGATCTCAGCGCTCAGCAGAGAGAGCAAAAACGTTTTGACTTCAATGCTGTCGATGATGAGGCTTCATCTAGCTCGAGAAGGAGCCATCTTACAGATCTTCTCCCGACAGCGGCCACCTCCTCCGCATGTACGTCATCAGCTATGCTGGCGGGTCCACCAATAGCTTCGACATCACGGGCTGCTGCTGAGGCGGCAGCGGAAGCGGCTGCTCTTGCCCAGCGGAAACCGCAGCGCCGCAAGCTCTACAAGTGTCCACACTGCGAGGCGATCTTCGAAAAGCTTAAGGAGCGTAATGCGCACATGATTGGCGAGCACAACTACGTGCGGCAAAATCGCCGTCTAATTTGCACTCAGCCGCAAATGAATACTTCGATGTTACCGCCACAGCAACAGATGATTATGCAGGCAGGTGAGGTTGAGGATTCCAAGGATGGCATTGTGAAGATAAAACAGGAGCAATGCCAGGAAAAGCATGATGTTGAGCAAATGCACGACCATTCCGAACTTTTGGCCGATGTCAAGGACTCAGAGCTGATGGGCATCGGCGGTGATGGTGACGGTGATGTAGATGACGACATTAAGCCACCCAACCAGCTAGATGAAAAGCCCACGCTGCCGCCATTAGCCATGACGACCCCAGCGGCTAAATTAGCAGCTTTGTATCGAATGCTCATCGCCTACAACGAATCCAAGCTCGGACAGGAGCGCAACAATCTTAGCGAGCTGGAGCAGAAGGCTATGGAAAAATCCATATTCCTCTGTTATGTCTGTCGTACCGACTTCCCGTCCGTAAAGCTCTATGACGCCCATCTCACCGAGCATCCCGCTGAATGCTTTACTTGCGGCAAGAAGTTCTACCGCTGGAAGAACTTCTCCTTGCACTTAAAGCGGCACTTGGGCTGGAAGGAGTTCGGATGCTATGTCTGCGACAAGAAGTTCGTGGTGCGCAGCGCCTTGGTCGAACACATGCGGATGCACACGGGGCAAACGCCACTCAAGTGCAAGATATGCGGTAAAAAGTTCAAGCGATACTCGAATCTGACGCAACACCGCAAACGCCACACCAAAATGATGGTGCGCAAGAAAGAGTACGTGTGTCACTGCGGCGAAGTCTTGCCCTCGAAGGCTCGCTTCCTGTGGCACAAGGAAACGCACGACCTGAAGCCGAAGTGCTGCCCGTACTGCTGCGATCGGTTTGTGCACGCCAACTCGCTACGTCGACACATACGGCTGGCCCACTCTGATAAGTTTGATTATGCCGAACCTATGGAATGCCCTATGTGTAAGCAAATCTTCGCGAAGACGTCCATCAAGGCGCATATGGCGACGCATTCAACGGAGCCCCAATACGATTGCGCCATTTGTAGCAAGAGCTTCTCCACCAAATGGAATCTCAAGATCCACTCGTGGGTACACGCCAACCGGACGGCCAAGCCCTTTAAGTGCGAATACTGCCCAAAGGCGTTCGTGCGAGAGTTGGACTTCAAGAACCACATCAACGCGCACAAACAGATCAAACCGTACACGTGCGAGTACTGCGGCTGCAAGTTCATCCGCAAGTACAATTACATGCGACACCGGCGCGAACATCATGGCACCAAGAAGTTCACCTGCGACCAGTGCGATAAGTCCTTCCATCGGCATTACTATCTGATAGAGCACCGGCGAATGCATACCGGAGAGCGTCCGTTCACGTGCACCATCTGCGGCAAGAGCTCCACAACTAAGACCAACCACAACAAGCATCTGAAGATCCACCATTCGCGCGATCCTTTCACGGTGGAGGTCTAA
Protein Sequence: MVDNSVQCPVCTLYLHAGMNLSDHLETHPKEQVIKALVQMTIVGNGGNSMGSVLAAAMLTGGTGGGGSSGGEASADEKPAVLSPPSGGDVKPVVANTISAATAPVLPPAPPPLSSSLVAACSNGAASSTTSSAPTSTSASNSSSKPSNPPMKALKCSPPTTEARASTSAHPTTSSVSTLYQPAQVTPDYRFNQQQPQTTGFGRGVTTSAAGLVIPQVPQQHFLASHQQQAHFPHQQQPPQQQQQHQPALKFSYATALPPPPPLQLFTQHQQQQTVVPPQTQQQSHQKPPPAYGAAISQIRSQHNQNKQQPQSQSVAMQHSLALAPTTTSAASTSHATATVKQTSKPQTEVFLNPPPPPSAQQQLQIHNLVQTQGQHHQHPHQQQSQPSQQSHQQPPSLQTYGLGVSSSCSSSNNPSTSGSGHRANRQTNSPFGALLNAAAAVACASPACPTTASSVLRFAESPVAHYLERENGDFIVQETPKHIVECVEKEDGEFSVIERIYQSPPSVLHIHDDDEDDEDEEEEHEHEAPPEEEDGDDEREENSHSRNMSKTTKKARKTKPKRGSKRMSDEEEFMSLSSGCESELEKEHKQEQLNAAASLPPPLCTAPSTSAAAGASTSNLADNHSNSASNSASNSNSTATTKSKKNRITVLSDVPLNMNEYLDLMGNIVASSRIGASRPFAAVAPIPLVKVEKEEPLDDYDNVAMAANAELEQKPSLEHGTTSVIRMASTAAASTSATATETSPEDLTQPPPMKVEVEATTTLLPQRFSTPAQHRGPKKLVIKPKQTAPATATTTKKTDTPSSPSNNPSISRDLVQVKSETLEAPATSSSILEKHLTASRKLLHHHSAVNDDDARVLLEFANSKQPPPLAASSTTFVVNASVGFPSAGSVFASSSSSCSKAPAKPGEEYILPDNNMDVDEIVISSSSSYTSTAAQVQNTLQPPDFNFLYHQATTTATTATYFNPFSRQQHHHQQQHGVSDATNAATLASSSSNSLDHDSMNATFRVAKTQSLQSWYQQEPDHDPQNQGGAESGTATPSNQSQDVVSHQPTNFNAALAAVDCCSVALDEDAKYLDLDACKREQLSSSSNLPSASASTTSSSFAGDGTESSLVGGLNIRTDEKMPAKGEISEQESNCDIENSWSESVYGDISQRYFRNQFSGGYNPDWRQDYYPAQDLSAQQREQKRFDFNAVDDEASSSSRRSHLTDLLPTAATSSACTSSAMLAGPPIASTSRAAAEAAAEAAALAQRKPQRRKLYKCPHCEAIFEKLKERNAHMIGEHNYVRQNRRLICTQPQMNTSMLPPQQQMIMQAGEVEDSKDGIVKIKQEQCQEKHDVEQMHDHSELLADVKDSELMGIGGDGDGDVDDDIKPPNQLDEKPTLPPLAMTTPAAKLAALYRMLIAYNESKLGQERNNLSELEQKAMEKSIFLCYVCRTDFPSVKLYDAHLTEHPAECFTCGKKFYRWKNFSLHLKRHLGWKEFGCYVCDKKFVVRSALVEHMRMHTGQTPLKCKICGKKFKRYSNLTQHRKRHTKMMVRKKEYVCHCGEVLPSKARFLWHKETHDLKPKCCPYCCDRFVHANSLRRHIRLAHSDKFDYAEPMECPMCKQIFAKTSIKAHMATHSTEPQYDCAICSKSFSTKWNLKIHSWVHANRTAKPFKCEYCPKAFVRELDFKNHINAHKQIKPYTCEYCGCKFIRKYNYMRHRREHHGTKKFTCDQCDKSFHRHYYLIEHRRMHTGERPFTCTICGKSSTTKTNHNKHLKIHHSRDPFTVEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00529734;
90% Identity: iTF_00591878;
80% Identity: -