Basic Information

Insect: Drosophila siamana
Gene Symbol: -
Assembly: GCA_035047445.1
Location: JAWNPP010000004.1:26469548-26473570[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00044 0.027 14.8 0.1 1 23 187 210 187 210 0.96

2 14 0.0018 0.11 12.9 3.1 2 23 259 281 255 281 0.89

3 14 0.013 0.8 10.1 0.9 1 23 376 399 376 399 0.93

4 14 0.43 26 5.3 5.6 2 23 448 470 447 471 0.95

5 14 0.0021 0.13 12.6 0.7 1 23 536 559 536 559 0.92

6 14 2.1 1.3e+02 3.2 0.1 2 14 578 590 577 602 0.85

7 14 0.00074 0.044 14.1 3.3 2 23 610 632 610 632 0.96

8 14 0.00097 0.059 13.7 0.1 1 23 739 762 739 762 0.95

9 14 0.00012 0.0069 16.6 0.2 1 23 827 850 827 850 0.92

10 14 0.0012 0.075 13.4 2.2 2 23 900 922 899 922 0.97

11 14 0.002 0.12 12.7 2.0 1 23 1010 1033 1010 1033 0.92

12 14 0.056 3.4 8.1 1.5 1 21 1085 1105 1085 1106 0.95

13 14 0.44 26 5.3 0.7 2 23 1158 1182 1157 1182 0.78

14 14 1.7 1.1e+02 3.4 0.6 1 16 1200 1214 1200 1224 0.75

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00044	0.027	14.8	0.1	1	23	187	210	187	210	0.96
2	14	0.0018	0.11	12.9	3.1	2	23	259	281	255	281	0.89
3	14	0.013	0.8	10.1	0.9	1	23	376	399	376	399	0.93
4	14	0.43	26	5.3	5.6	2	23	448	470	447	471	0.95
5	14	0.0021	0.13	12.6	0.7	1	23	536	559	536	559	0.92
6	14	2.1	1.3e+02	3.2	0.1	2	14	578	590	577	602	0.85
7	14	0.00074	0.044	14.1	3.3	2	23	610	632	610	632	0.96
8	14	0.00097	0.059	13.7	0.1	1	23	739	762	739	762	0.95
9	14	0.00012	0.0069	16.6	0.2	1	23	827	850	827	850	0.92
10	14	0.0012	0.075	13.4	2.2	2	23	900	922	899	922	0.97
11	14	0.002	0.12	12.7	2.0	1	23	1010	1033	1010	1033	0.92
12	14	0.056	3.4	8.1	1.5	1	21	1085	1105	1085	1106	0.95
13	14	0.44	26	5.3	0.7	2	23	1158	1182	1157	1182	0.78
14	14	1.7	1.1e+02	3.4	0.6	1	16	1200	1214	1200	1224	0.75

Sequence Information

Coding Sequence: ATGGAAGGTATGGATCTGTGGACGTCTATGTTTTCGGCCGACTTTGAGGAGGGTGATGGTGTGGGTGATAATTATAATCATGACAGCAACGCGCACGCAGACGAGTTTATTGGTGatgaggaagaggaggaggaggaggaggaggcggaacaggagcaggagcaggaggctGATATCGATGAGCTGGAAGACGAAAGAGACACCGAGAGGGAGAAGGAGGGTGACGACAGTAGACGACGGCAGCGTAATAAACAGGAGAAAGGAAATGAGCCCGATGATGATGccatatttgattttgaactTGAGCCCATCATTAGCATTGCTGAACCGAAATTGGAATCTGTGCGCCGAGGAACTGTCGCCTTAGCGCCACCAATGCCAACTGCTCCACCAGTACGTGCCATGCATCGACAATCGCTGCCAGCCTCGTTCGGTTCATCGTTGATGCCACGAGGAGGATCTGTTGTGGGTGCAACTGCTCCAACGCGTCCTACAACTTCTCAAATCAATGCCACCGATGAAAATGGCGTTCCCATAAACTATGAATTGGGTGTAATTTACATTTGTCCGGCATGCGGTGCTGAGTATCGACAGCAGGATATGTGGAAGCGACACATGAACCAGATGCATCAGTACAACACACGCAAGGGACTCAATTTTGTGGCCATCGATAAGCTGTATCATCGGTGCTTGGAGTGCAATAAGCGCATTGCGATGCACAGTCGAGAGAATCTACTAAAGCATAAGTTCACCCATTTGCCATACCGATGCACCAAGTGTTTCATATGCAAGCGAGAGTACAAATATAGGCAGGACCTGATGGTGCATTTGCGCATGGTCCACTGTGACGAGGTGGTAGCCATGATGCGAGACGGCGACACTAGCGCTGGACGTAAGACGCGTGTCCGCGAGCCACGCACCGAGCAGCACTCCAGTCAACAAACTGTTGCAGGCtttgatgatgacgatgccaTACAAGTTAAGAGCGAGCACGTGGACACGGATGGTGCATCAGTGGAGGATGATGTTGTGGCTGGCAGCTCACAAAAGCGAAAGCGTAGCAAtccagcagttgcagctggcaaCGGGAGCAGTGCTGCTGAAATCTGTGAGGATTACATACATTACATGTGCCCGGACTGCGGCACCGATTGCGACACTCATGCCCAATGGAGTCAGCACATCGAGTTCGTGCACGATTATGTCAGCAGACGAGGCCTCAACTTTCGCTGCGTGGACATGCAGATGCAATGCCTAGAGTGCAAACAGTTTGTCATCCCGAATACAATTAAGACGTTGCGGGCTCACAAGTTTAACCATTTGCCACAACCCAATTGGATGCGCTGCAAATTGTGCTACAAAGGTTATACGGAGCATCATGAGTTGGTGACCCATTTGCTCAAGCAACATCACTTGGAGACGTTAATGCCCGACGTTGAGGAGACCGAGGAGCCCATCTCCAGTGCCAACGATggtgacgatggcgatgataaaactggcaatggcagcggcaatgGCTGCGAAGAGGAATTGACACATTGGGACGAAGCACCACGCCGTGGCGGACGCATCAGCAGTGATGACATGTATGAACCCCACATTGACTATCTCTGTCCACAGTGCGGCAGAGAGTTCATCGAGAAGAAGCACTGGCGTACTCACGTCGTAAAAGTGCATGGCATGAACGATCTGAGCAAGCTCAACTTTGAAGTCATCAACGACAGACAGCTAAAGTGCACGGAATGTGACAAGATCATCACGAACGCGTATGGTATACAGAATGCTCAACAGCATCGCATTACGCACTTGCCATATAAGGCGTACGCCCGATGTCGCAAGTGCCACAAATCGTACACGGATCGCAAAGGACTGGTCAAACATTTGGCCACATATCATCGTGTTGGCTACGAGCCGCgtaaggctgctgctgcagcaactgctgctggcacGAGTGCGGGCAGTAGTCAGACTTCCAAGGCACAGACGCCGCGCAAACAAATTGTAACTATAGCCAATGAAACATATGAGATTATCTATTTGGATGAGGAGCAATCGTCGCCcggcaataataatattaacgaGGAAAATGATTTTGGAGAACAGATGCaaggcgatgatgatgactttGCCATCAGTAATAGTGCCATCAGTAGTAGCAACAGTCGTCAGTTGTCAACAGCTGCCATGtccaatcacaatcacaatcccAATCGTTATAAGTGCGTTGACTGCGGCTCCTTGTTTCCAACGCAAGCGGCACTCAAGACGCACATTAGCGAAGAGCATGATTTTATGGATGCTCACTACAGTGCCAAAAAGTTTGACAATGCTGAACCGACTGATGAGACAGCTCCGGTCTCGGCTTTAGGTCCTGCCCAAGCGCCTGCATCAGCGGCCACAGCTAAAACCTCATTGGGCGTTAAGAAAACGACACAATTGAATCCATCGGGCGTCTCAACTATTGagcaaaattatatattccTATGCCCCTCGTGTGGCAAGGCCTACAAGACACAGTTTGAGTGGCGTCGCCACATTAATGACGCGCATAACTTCGACAAGCGGCAGTACTTGAATATGCGTCAGTTGGACAAGTATCGGTATCAGTGCACTCAGTGCAAGGATATTGTGAGCAGCTCGAAGCTAAAAGGTTTGCAGGATCATCACTTTCGCCATCTGCCCTATCGCTTGTACTTAAAGTGTCTCGTCTGCGGCACTTGCTACAATCACAAGCCCAACATAGCAGCTCATCTGCGTACGCGTCACAACATCTACGAACGTGATACGCCGTGGCGCGAGTTGCAGCCGAAGCCACAGTACAACTATGTGATAATGAAGGATAAGGACAAAGATAAGGAAGCTCGTGCCATTTCCTCACCATCGTCGCCAACacctggcagcagcagctgtaatGCAGGTCGCTCCTTAAAGCCGCAGCCAGGCCTGTTGCCCACTCGCCCAGCAGGACTGAATACGCTGGAGGATAGCATTTCATATCATAACGCTGTGGACTTGGACTTCATCACGTACTATTGCCCCAAATGCAATAAGAACTTTGATTCGCATGCATTCTGGCGCAAACACATTGTGGAGCAGCATAATTACAACAGTCGTCAGGGTCTCAATTTCCGCCAAATCGATATTCATCACTATTTGTGCCTAGAGTGCTACAAACGTGTTACTGTCACCCACACCAAGGGCGCTATTGGTCAGTTACAGTCACACAAGTTCCGACATCTCCCCTACCGATCCTTTAAGTGCCTGACATGCAATGGAGAATTTGTGCGCAAGCAAATGTTCTTTAAGCACCTAAATCGCGATACTAATCGCTGTGACAACAAGCCTTTGAGTGCACAAGAAACCGACGACGATGGTGCAGAGCAGCCAGAAAGCTCAGCCGGCGATGGCGGTGATGGTTTattgcctgttgctgctgccttggaGGATGTTGATCCCGCTGCTTATCGCCTAAGATGTCCGCAATGCGGCGACAACTTTACCACAAGCAGCAAGGCGTTGTGGCGCGAACACATTAACATCTGTCATGGGCTGGGCAAACGAGAGCTGCTTCATATGCGAAAGATTGGCGAGGAGCTCTATCGCTGCACCGACTGTGATGAGCAGTTGCAATCAAAGCATTTGCGGGTGCTGCAGGAACATCGCTTTCGGCATTTGCCCTATGCGGACTACATTCGATGCCAGTTGTGCGAACAGCAGACGGATGAACTGGATCACGGGGATGTTGCAGCTGGTCTGCACAGTATGCTCGAGTTGCAGCAACACATACGCGAAAAACATCCCGATATGGCTGACAACGATGAACAACTGGAAACACTTcttgataatgatgatgacagTGACCCTACGAAAAATGAGTCTGCGGGGAATGGACGTTATATGCCGCTACCGCCGCATTTATTAGATGACGATGACATGGAATATGAGGATCAGTATCTGCTTGGCTAA
Protein Sequence: MEGMDLWTSMFSADFEEGDGVGDNYNHDSNAHADEFIGDEEEEEEEEEAEQEQEQEADIDELEDERDTEREKEGDDSRRRQRNKQEKGNEPDDDAIFDFELEPIISIAEPKLESVRRGTVALAPPMPTAPPVRAMHRQSLPASFGSSLMPRGGSVVGATAPTRPTTSQINATDENGVPINYELGVIYICPACGAEYRQQDMWKRHMNQMHQYNTRKGLNFVAIDKLYHRCLECNKRIAMHSRENLLKHKFTHLPYRCTKCFICKREYKYRQDLMVHLRMVHCDEVVAMMRDGDTSAGRKTRVREPRTEQHSSQQTVAGFDDDDAIQVKSEHVDTDGASVEDDVVAGSSQKRKRSNPAVAAGNGSSAAEICEDYIHYMCPDCGTDCDTHAQWSQHIEFVHDYVSRRGLNFRCVDMQMQCLECKQFVIPNTIKTLRAHKFNHLPQPNWMRCKLCYKGYTEHHELVTHLLKQHHLETLMPDVEETEEPISSANDGDDGDDKTGNGSGNGCEEELTHWDEAPRRGGRISSDDMYEPHIDYLCPQCGREFIEKKHWRTHVVKVHGMNDLSKLNFEVINDRQLKCTECDKIITNAYGIQNAQQHRITHLPYKAYARCRKCHKSYTDRKGLVKHLATYHRVGYEPRKAAAAATAAGTSAGSSQTSKAQTPRKQIVTIANETYEIIYLDEEQSSPGNNNINEENDFGEQMQGDDDDFAISNSAISSSNSRQLSTAAMSNHNHNPNRYKCVDCGSLFPTQAALKTHISEEHDFMDAHYSAKKFDNAEPTDETAPVSALGPAQAPASAATAKTSLGVKKTTQLNPSGVSTIEQNYIFLCPSCGKAYKTQFEWRRHINDAHNFDKRQYLNMRQLDKYRYQCTQCKDIVSSSKLKGLQDHHFRHLPYRLYLKCLVCGTCYNHKPNIAAHLRTRHNIYERDTPWRELQPKPQYNYVIMKDKDKDKEARAISSPSSPTPGSSSCNAGRSLKPQPGLLPTRPAGLNTLEDSISYHNAVDLDFITYYCPKCNKNFDSHAFWRKHIVEQHNYNSRQGLNFRQIDIHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPYRSFKCLTCNGEFVRKQMFFKHLNRDTNRCDNKPLSAQETDDDGAEQPESSAGDGGDGLLPVAAALEDVDPAAYRLRCPQCGDNFTTSSKALWREHINICHGLGKRELLHMRKIGEELYRCTDCDEQLQSKHLRVLQEHRFRHLPYADYIRCQLCEQQTDELDHGDVAAGLHSMLELQQHIREKHPDMADNDEQLETLLDNDDDSDPTKNESAGNGRYMPLPPHLLDDDDMEYEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: iTF_00589796;
80% Identity: -