g2599.t1
Basic Information
- Insect
- Drosophila pseudoobscura
- Gene Symbol
- rfx7.L
- Assembly
- GCA_009870125.2
- Location
- CM020868.1:20960488-20964847[+]
Transcription Factor Domain
- TF Family
- RFX
- Domain
- RFX domain
- PFAM
- PF02257
- TF Group
- Basic Domians group
- Description
- RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 1.5e-32 1e-28 99.9 0.1 3 78 304 379 302 380 0.97
Sequence Information
- Coding Sequence
- ATGTCCGAGAAGCATGGCCAGCTGGGTGCGCAGTGGACGAAATCAGCGGCGGCgccaacagccgcagcagcagcagcagctctagCCTCGGCTTCCACCCCGCTCCAGAAGCTcccgaatccaaatccgagTCCAAACTTTCCAGCCAGCAGTCATCCGTATGGCAACTGTGCGATTCCTGGACTCCCGGGCATACAGCCAGCGGACATACCGTATACCTCGGGACGGTTTCAGGCCCCGTCCATCATCCATGCCAAGGCCTCGCCCCTGACCATCGTGCCAGTGGGCACTGCCATTGGGCCCCACTGTCCCCCCCAGGTCTCGCCCACGAGCCACCACACAAATGTACCTGTATCCGTGACCGTACCCGCTCCCAGCGGCTTTGTGCCGACGCCGTTTACAAATGCTGGCAGTGGCACGACGTCCGTACTGCAACCGAATGCATTTGCAACGGCCGCGGGAAATGCCTTTGCGAATGCGCTCAACTTTAATACGGCCCAACAGCTGATGCATGCCATGAGTACAGGCacggcagcagccaccaccacaccgatcacagccacagcgactCCTGTCATAGCGGGCGGGGGTCCTGCTGCCCAGCGGCATCCCGTCGAGCCGGTACCCACGACAAGCGGCGTCATTAATTCCACCATTGCTGAGAATGTCATGAATGCGCTGTCCAACTCGACCGCTGCCTCCGAGGAGAAGATGCGACGCGTGCAGCAGGTGATTGAGGCCAGCATTGAtGACAATGCGAAGCTACAAATCTCGCAGATCCTCGAACGTGTTGCAGTCTTGAAGCCAATCGAAAAACTATTTCTCTATCTGCGTTTGCCGGGGGAGTGCGCGGACTCGGATCCATTGAGACAGCCACAGAATCCGCTGGGCACACGCTCAGAGATCAATCACACCATCAATTGGGTGCGCTCTCACCTGGAACACGATGCACAGGTCTCCATACCAAAGCAGGATGTATACAATGATTACATTGCCTATTGCGAACGCCTGAGCATCAAGCCCCTGTCCACGGCAGACTTTGGCAAAGTAATGAAGCAGGTCTTCCCGGGCGTGCGTCCACGTCGTTTGGGAACGCGTGGAAACTCTCGCTACTGCTATGCGGCCATGCGAAAGACCACAAAGCTAACGCCGCCACAGTTGCCGGCGCTGTGCAAAACCGAACAAACCACAGGAGACgaagctgctgctccagccaTAGCCACTGCACAGATGAATCACTCCCCGGGTGTTGTGCTGCCTCCCATGCCAACAGGCGACAGCGAGAACTGGGATGTGGTGCGCAGTTGGGCGGAGAAGCTGCTGAACACAAAACTAGACAGCATTGCAGAGCTGAGCACGCGGATCAAGAGCAACAATGCCACGGTCATGGGCGTGCATTTGGGCGCCAAGAAGTACACACCCCGGGAACCCAAAGAGAAGCGTGTTTTGGCCGATATGGGACCACTGAAGAAGCGACGCAAAAAGAAACGCAAGGGCTCGACATCCTCAGAGTCGAGCTGCAATCAATTGGTGGCTGGGCTGCAAGATGCAGGCAGCAGTCAAGATGCCATTGATGAACCGAAGACGGAGCAGCTAGTAAAGATCAAGCAGGAGATTATAGACTCCCCCGTACACCAGTcccagcaccaacagcagccacagcagcagcagcccccaaTGAATTATCTGCATCAAATGATGCCCATGAACCTGGCCACAGAACAGCGAAGCAACAGTGCGGTGCGTAATCTGACGCCCAAGATCATGGAGATGGGCGTGGCTGTACCCCCAACGGTAGTGCTCACACAGCAGCAGGATGAGCCATCGCCCACAACGATGGTGATCAAGGACGAGGTGGAGGACTACAATACATCCAATATATTCTGCAAAAAAGTGTTAAAGGCCCAGCAAACGAAAGGATTTTGGGCCAATTCCCCGAGCAGCGGTACAACGGGCGGCGGGGGAACCCTGCTAGTGCCGCCCGTGATCACAACGACTGCGGCGACACCACCGCCACCGGACATCTCGCCGGGACCCATGTCCATGGGACCGCCAGCGCAATTGATGATTTCCAGTTCGGTGAGCCCCTCCAGCAGCAtggacagcaacaacaccacaCCGAAGGTGGTCTCCAGCAACATGATACTGCTGCGTGCAAAGCGCCTGCTGGCGGCGGAGAGTGCCGCTGCCCTGACGGCCGCTGCAGACGATTCGGGACTACCTGAGAATCTGGGTTTGCCCAGGGAGCGGGTGATTAGCATCTGTAATATGGATAAGCACGAGCTGGACGATTATTTCCTGCCCGTTGAGGATGAGGAGAACTCCGAGGAGCCCGACACCGAGCTGCTTCAATATTTTCAGATGGGAGACGCTGAGGAAAAACAACTGAATTCCTTAGATGCTgtagaacagaacagaaatcCACAAGGAACACCGATAATAACGTCGACGACGACAGCGATACAGGCGGGAATGGCGCCAGCGATGCACCAGCAACAGACCCATACCCAGCACCCCCAACCGCCGAATCGTGGAGCCACAACGGCCATGCCCTCGCCACAGGGGAGCTTGGTCGTCTCATCGACAATGTTGTCCGGTCAAGCGAATGTGGGTTCTGCCTCAGCGTCTCTGGCTTTAATGTCAAAGAAgcatcaacaccaacaaaaccaaccacaacaacagcagcagcaacagcaacagcagctgcgaACCAAACAGCTGCCAACAAACGGCAATTCTAACCCGAACAACAGGCGAAAGATCAGCCTGAGCAATGCCTCTAGcaatggcagcaacaaaaattgcatatttCTGCCAATATCCCCCAACATCAACAATGGAGGCggatcagcaacagcagcagcaacaggaggcaCAACAACGAATCAAATGCCGCAGCATCAGAATCCAACAAATTCCAATCAACAAAATTGCTTTGCCAGTCCTGGCGTCACGCGGATGCGGCAACGTTCTAGTCTGCTGACCAAACAGCAATCCCTTGACTGCGATGGCAATCGTGATCCCATGATTGGAGCAACGCGTAGAAAACGTTGCTATGTCTATAGCTATCCCACAAGCACGTCGGCCTCGGCGCCGCCCAGCCCCTCGCTGCTGCAGCAGTGCATGGTGGGAAATTGGCCATTTGGTGGAACAAACTCCTTCCAAGACACGAACAGTGCGGATCCCTTGATTAACCAGAACTCTATGGATCTCGAGACGAGCCTGGCCCTGACGGGTGGCGACGATCTGGATCTAACGGAGACGCAACGCTCGCAATCGGTGCCGCTGTCACAGCTACAGAGAAGCTGCCATCCATCGCCCAGCTTCAATCGGCAGGCCAGCTTTCAGGCCTCGAGCTATGCGAGCGACACCTTCTACTCggagaacagcaacagccaaaaTTCGGTGGCAGTGGCCCCCCTAAAGGACGTGGAGGCggctgctgcgctgctctaCGAAGTGGATGTGGCTGCCATTGTATCGCCGAGCTTCAACAATAAGTTTGGGAACATATCCCAGCAAACGGCCACCACATGCAGCTCCTCGGCGGGCTCGTCCTCTGGCTACAGCAGCGGAGGCTCTGCGGGCATTGTCTCACGCTCTGTGCCCTCCACACCACTGCCGCATCAGCAACAGAACAACAATCTGACAGGCTTTAATGGCAATGGAGGTGGCAATGgcgctggaggaggaggcggcaacCTGAATGCCACAAATGGTTTCTTCAACATCTCGCCATCGTTCAACTGGGAAACATCGAGCAATGGCATTCAAGGGGGATCCTACCTCTCGTACAGCGCTCGCAATACGATGGATATATCCAAGTCGATGCCCACGACGCCCATAACCACGCCCTGCTTTCGCTATAGTCCCGTGGAGTTGCACCGGGATTTCCTGATCAATGGCTGCACCATCGACCTTGTGCCCTCGTCTGCGTTTGTCCCAGCGTGCAGCGATGAGAATCCGGCTCTGACCCTCAGCTCGGACTCGCTGATGGATGACAGCTCGCCCAGTAGTATACTGGATACCTTAGAGGAAAAAGGAGAGGAGAAGGTGGATGAAAAGTCTGTTTCCCAAATGCCAGAAGATGCCACAGTGGTGGCCTATCTGCTGGAGCATGTGGATCAGTTGTAG
- Protein Sequence
- MSEKHGQLGAQWTKSAAAPTAAAAAAALASASTPLQKLPNPNPSPNFPASSHPYGNCAIPGLPGIQPADIPYTSGRFQAPSIIHAKASPLTIVPVGTAIGPHCPPQVSPTSHHTNVPVSVTVPAPSGFVPTPFTNAGSGTTSVLQPNAFATAAGNAFANALNFNTAQQLMHAMSTGTAAATTTPITATATPVIAGGGPAAQRHPVEPVPTTSGVINSTIAENVMNALSNSTAASEEKMRRVQQVIEASIDDNAKLQISQILERVAVLKPIEKLFLYLRLPGECADSDPLRQPQNPLGTRSEINHTINWVRSHLEHDAQVSIPKQDVYNDYIAYCERLSIKPLSTADFGKVMKQVFPGVRPRRLGTRGNSRYCYAAMRKTTKLTPPQLPALCKTEQTTGDEAAAPAIATAQMNHSPGVVLPPMPTGDSENWDVVRSWAEKLLNTKLDSIAELSTRIKSNNATVMGVHLGAKKYTPREPKEKRVLADMGPLKKRRKKKRKGSTSSESSCNQLVAGLQDAGSSQDAIDEPKTEQLVKIKQEIIDSPVHQSQHQQQPQQQQPPMNYLHQMMPMNLATEQRSNSAVRNLTPKIMEMGVAVPPTVVLTQQQDEPSPTTMVIKDEVEDYNTSNIFCKKVLKAQQTKGFWANSPSSGTTGGGGTLLVPPVITTTAATPPPPDISPGPMSMGPPAQLMISSSVSPSSSMDSNNTTPKVVSSNMILLRAKRLLAAESAAALTAAADDSGLPENLGLPRERVISICNMDKHELDDYFLPVEDEENSEEPDTELLQYFQMGDAEEKQLNSLDAVEQNRNPQGTPIITSTTTAIQAGMAPAMHQQQTHTQHPQPPNRGATTAMPSPQGSLVVSSTMLSGQANVGSASASLALMSKKHQHQQNQPQQQQQQQQQQLRTKQLPTNGNSNPNNRRKISLSNASSNGSNKNCIFLPISPNINNGGGSATAAATGGTTTNQMPQHQNPTNSNQQNCFASPGVTRMRQRSSLLTKQQSLDCDGNRDPMIGATRRKRCYVYSYPTSTSASAPPSPSLLQQCMVGNWPFGGTNSFQDTNSADPLINQNSMDLETSLALTGGDDLDLTETQRSQSVPLSQLQRSCHPSPSFNRQASFQASSYASDTFYSENSNSQNSVAVAPLKDVEAAAALLYEVDVAAIVSPSFNNKFGNISQQTATTCSSSAGSSSGYSSGGSAGIVSRSVPSTPLPHQQQNNNLTGFNGNGGGNGAGGGGGNLNATNGFFNISPSFNWETSSNGIQGGSYLSYSARNTMDISKSMPTTPITTPCFRYSPVELHRDFLINGCTIDLVPSSAFVPACSDENPALTLSSDSLMDDSSPSSILDTLEEKGEEKVDEKSVSQMPEDATVVAYLLEHVDQL*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00471352;
- 90% Identity
- iTF_00574553;
- 80% Identity
- -