Dpic005996.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila picticornis
Gene Symbol
Rfx2
Assembly
GCA_035043845.1
Location
JAWNMR010000362.1:16334993-16341352[-]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 6.2e-38 5.1e-34 116.6 0.1 3 78 344 419 342 420 0.97

Sequence Information

Coding Sequence
ATGCATTCGCGATTCGGCTTCGACTGTCAGACGCGTcaccaccaacaccatcaGCCACACCACCtgcatcatcaacagcagcagcagccgcagccgcatcAACACCATCCTCAGCCACAGTCGGATATTACgtcaccgccgccgccgccgatCGCCGCCGCCTATACGAATCTCTTGGAGAAGTGTCGTTGCAAGCTGCACTCACATCCACACCACcctcagcatcagcatcagcaccagcagcagcagcagcaacaacagcatccatCGCAGCCGTCACATCCACaccagttgctgccacaccaacagcaacagttgccagtgGCGGCGTCAGCAGCGTCACTAGCGCCGCTGCCAGCGgcccagttgcagttgcaactgcaccatcatcatcatcatcatcaccatcagaCGTTCGTGGCCACGGCCAGTGCCGtcaactacagcagcagctgtacgACAATTggcgccgctgccgccgcctccACAGGGACAGCATCGAGctcagcagcaaccacagcaatgtatcaccatcaccaccatcgACGTCACAACAATTTGTCCTATTGCGGTGTTTCTGGTCAGGAGCAAAACTATCAAGTGCAATATGTTGATTCGGAACTATATCACAGCAACTCGAGCCAGACGCAAATGACGTACCCATTCTGTCCGGTGGGCGATTATCAGGGCAATGGCCAGACGTATTACTCGACAACGGCAGCCACTGGCAACTATGCAACAGCGGCGGCAGGCAGCACAGCAAATGCCCATTCCACGACGCTGCCGTATCTGGTACCTGTCGACGAGAGTCTGCTATTGAATGGGTCCTCGCAGTCACACAGCCGGGACTCGCCGCACAGCTTGACGCATGAGGTTGCCTACATACAGGAGGCGCAGAGCACACCACAAACGCCCACCTCGACAACAACCACCAATTCGGCCAGCGGCGGCAGCATCGGCAACGGTGCCGATGGGGCGTCACCCGATAGTGACCAGAGCGCCATGGGCGCCAGCAACAAGATTGCCTCGGCAACGATTAAGTGGCTGTCGCGCAACTACGAGACTGCCGACGGAGTTAGTCTGCCACGTTCAACGTTATATAACCACTACATGCAGCATTGCAACGAACAGAAGCTGGAGCCAGTGAATGCAGCCAGTTTCGGCAAGTTGATACGCTCTGTGTTCTCTGGTCTGCGCACACGTCGCTTGGGCACGCGCGGCAACTCCAAGTATCATTATTATGGCATTCGCATCAAGCCCGGCTCACTGCTAATTCATCAATCCATGGAGGACAAAGCTATGCAGGGCTATGGCACGCCAACGGGCAATGGGTCCATGGccaacgtcagcagcagcagcatcggcgCCACCCAACTGGGCAGCAATGGCTTATCATCGAATTCTGGCCAGCGCTCAGCTGGCGCCAAGAAGCACAACTTCAAGCCGGAAACCTACGAGGCTTGCATACAGTACATTGGCGACGGTGCGGGCGCCATGCCCGTCTTTCCGGCCATCGAGCTGAGCCACAGTTTTCACAGTGAACTCACCCTGGACGATGTGGACACTTTTCGTGCACTTTACCGCGAGCATTGCGAATCATTTTTGGATGCTGTGCTCAATCTGGAGTTTGGCACGGTTGAGTTTTTGCTGCGCGACTTTTGGCGCACCAcggacaacaacaatctgGACGAGTGCGAGGAGGAGAAGTACTTGAGCAAGACGAAACTGTATCTGTTGTGCCACTGCGCAGAAGTGCAAAAGTTTGTGCGCGAGGTGGACTATCAGTTCTATCAGAACACCGTGGACGTTATAATACCAGATGTGCTGCGCTCGATACCCAACGCACTGACTCAGGCCATACGCAACTTTGCCAAGAATCTGGAGCTGTGGCTGTGCGAGAGCATGCTGGGTGTGCCGGAGCAGCTGTCACAGATCAAGACTAGCGCCGTCTCGGCATTTTGCCAGACGTTGCGTCGCTACACATCCCTGAATCATCTGGCGCAGGCAGCACGAGCCGTGCTACAAAACGGTGCACAAATTTCCCAAATGCTCAACGATCTGAATCGTGTGGACTTTCACAATGTGCAGgaGCAAGCCGCCTGGGTTAGCCAATGTGCACCGGATGTGGTGCAGCGTCTGGAGAACGATTTTAAGGcagcactgcagcagcaaagctCACTGGAGCAATGGGCTAGTTGGCTGCAGCTTGTGGTGGAGTCCGCTATGGAGGAGTATACGGGCAAACCGAGCTATGCGCGTGCAGCTCGTCAGTTTCTGTTGAAGTGGAGCTTCTACAGCTCGATGATAATTCGAGACTTAACACTGCGTTCCGCATCGAGCTTTGGCAGCTTTCATCTGATCCGGCTGCTGTTCGATGAGTATATGTTTTATCTGGTGGAGCACAAGATAGCCGAGGCGCAGCAGAAGACGGCCATTGCGGTCATTTGCGAGCGCATGAAGAAGGAAATGGACTTTGAGTTCGAGTGCCAGTTCGCCTATATCACCAGCGATGGGGAGCAGCAAGCAACGGCCACCTCTGTCGGTGGCGGCGGCGCCaatggtggtgttggtggtgctggtgccgtaggtgttgctggtgttgcacCGACTGCGGCAAGTGCCACTAGTGCTGGCAACGAAGCCAAGCGTCTGAAGCAGGAATGA
Protein Sequence
MHSRFGFDCQTRHHQHHQPHHLHHQQQQQPQPHQHHPQPQSDITSPPPPPIAAAYTNLLEKCRCKLHSHPHHPQHQHQHQQQQQQQQHPSQPSHPHQLLPHQQQQLPVAASAASLAPLPAAQLQLQLHHHHHHHHHQTFVATASAVNYSSSCTTIGAAAAASTGTASSSAATTAMYHHHHHRRHNNLSYCGVSGQEQNYQVQYVDSELYHSNSSQTQMTYPFCPVGDYQGNGQTYYSTTAATGNYATAAAGSTANAHSTTLPYLVPVDESLLLNGSSQSHSRDSPHSLTHEVAYIQEAQSTPQTPTSTTTTNSASGGSIGNGADGASPDSDQSAMGASNKIASATIKWLSRNYETADGVSLPRSTLYNHYMQHCNEQKLEPVNAASFGKLIRSVFSGLRTRRLGTRGNSKYHYYGIRIKPGSLLIHQSMEDKAMQGYGTPTGNGSMANVSSSSIGATQLGSNGLSSNSGQRSAGAKKHNFKPETYEACIQYIGDGAGAMPVFPAIELSHSFHSELTLDDVDTFRALYREHCESFLDAVLNLEFGTVEFLLRDFWRTTDNNNLDECEEEKYLSKTKLYLLCHCAEVQKFVREVDYQFYQNTVDVIIPDVLRSIPNALTQAIRNFAKNLELWLCESMLGVPEQLSQIKTSAVSAFCQTLRRYTSLNHLAQAARAVLQNGAQISQMLNDLNRVDFHNVQEQAAWVSQCAPDVVQRLENDFKAALQQQSSLEQWASWLQLVVESAMEEYTGKPSYARAARQFLLKWSFYSSMIIRDLTLRSASSFGSFHLIRLLFDEYMFYLVEHKIAEAQQKTAIAVICERMKKEMDFEFECQFAYITSDGEQQATATSVGGGGANGGVGGAGAVGVAGVAPTAASATSAGNEAKRLKQE