Dpha018385.1
Basic Information
- Insect
- Drosophila phalerata
- Gene Symbol
- salm
- Assembly
- GCA_951394115.2
- Location
- OX596008.2:19514084-19528314[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 8 2.6e-06 0.00026 21.8 1.7 1 23 363 385 363 385 0.98 2 8 3.7e-05 0.0037 18.2 3.5 1 23 391 413 391 413 0.98 3 8 2.6 2.5e+02 3.0 2.4 5 23 659 677 656 677 0.84 4 8 3.9e-08 3.8e-06 27.6 0.2 1 23 683 705 683 705 0.98 5 8 0.0012 0.11 13.5 0.9 1 23 715 737 715 737 0.98 6 8 0.058 5.8 8.1 0.1 2 23 937 959 937 959 0.96 7 8 1.3e-05 0.0012 19.7 5.0 1 23 1095 1117 1095 1117 0.96 8 8 1e-07 9.9e-06 26.3 0.7 1 23 1123 1145 1123 1145 0.98
Sequence Information
- Coding Sequence
- ATGTGTTCAATATTTCGTAATCGCATCAATTACCGGGGCACAGGGACGCGCAGTGGCGCCTCCGGCGGTGGCACAGCCCCAACCAATGAGAGGGAAAGTCTGCTGGCCAAGGAGCTGAATGCGGATAGCAATAACAATGGCAGTGGAGTGGAGGAGGTGCCACAACTTCATCCCGATGcagatgcggatgcggatgcgggtGCAGAGCTTCAACTGGAAGCATCGTTGGAGACATCGTTGCCGGGGAACTCGGAGCAGCAGCCGGAGAATAGCAATGAGGCGTTGGATCTGTCGGTAATCTCCGGCAACCGTTTGCCCACGTCGGGGCATGTGGCACTTGAAGCTTTACAACATACCAAAGTGGCGGTGGCGCAGTTTGCAGCAACTGCGTTGGCCGGGGCAGCTGATCCCACGGATCTGGCCATGGTCCAGTCGACGATCTTCAATGTGCAGCGACAGCATCTGATGCAGCTGCAGCTCATCCAACATCTACAGAGTCAATTGAAGCGGGCGGGAGGCGTGGTCGCTGCTCTCAGCAGACAGGGAGATCCGAACGAGGAGGAGAAGGACGACTTAGACGAggaggagggggagggggaggaggaggaggaggaaaaTCCTGCCAAAGAACAGCCGATGGTTAATGGCGAGAGAGAGGCGGCAGAGAGAGAGCAGGAGAGTTTAAAGACTGATGGACAGGACTTGTCCATGGAAAAGGCTAAAGAGTGCAATAAGGAAATGGAAAAGGGAAAAGGGAGGGGGATGGAAAGGGACATGGACAGGGAAAGGCAAAGGGAGCAAGTCAAGCGGGAAAGCGAGCGTGAGATTGAAGCTGAAGTCGAACCCGAGACGGAGAACGAGTATCAACCGTTAATGTGCGACATCAGCTCCAGTCTAGCCTCGAGCATCATCACCAACCACGACCCGCCGCCGGCACCCAATGAGCCCAACTGCCTGGAGATGCTGCAACGACGCACAGAGGAGGTGCTGGACTCTGCCTCGCAGAGCTTGCACGCGGCACAGATGCAGGAGGAGTACTCGGAGTATGCCTCAAAGGAGGCTCAGAGTCGAGGGGAGATCTTCAAGCATCGTTGCAAGTATTGCGGCAAGATCTTTGGCAGTTACTCCGCCCTGCAGATCCATCTGCGTTCCCACACGGGCGAGCGACCCTTCCACTGCAACGTCTGTGGCAGCAAGTTCACCACAAAGGGTAATCTCAAGGTCCACTATCAACGGCACACGCAGATCTTTCCTCCAATGCTGCTGCCCCCTGTAGTCAATGGGGCAGGACCTTCCGGGCCTAGCCCCGAACAGTTTGCCGCTCTCACGCCCATTCGATTACCCTTTGTGCCGCCTGCGCCGCTAGCTCCGCCTCCACCTCCCAGCAGAGATCCGCCAGCAGCGGAGCAGCCTCAGTCCcagcctccgcctccgcctcaGCAGCAACctccacagcagcagcaggagcagcaagTGCCACAACAGGCAGAGGATCTCAGCAAGCCCATGCGGGAAAGGTCTAACTCGCCTGTGGAGCGAGAAGCGACACCGATAAAGTCCCTGCCCGATCGAAGTCGCGTCGTAACGGAGCCAGATCAAGCTTCACCCGAGAAGCAGGAGAAGGAAAGGCCCAAGGACAGTCCTAAGCCCACAACACCCACAGCATCCAACCGTCGCAATGGCAGCGTGCGAAAACGCCAGACGAGCAATGCTGGAAGTCCTCCCGGGGAGGAACGATCCGCGGATCATGCCGAGCATCTGCACATTGCCAAGCTGGTGCGTCGCTCCTCGGCCAGCCGTGATGGCTCTGTCGGAATGCCGGTAGCCGGAGAATACTCCCTTGCACAGATGGAGCGCATCATAGACAAGTCGTGGGAGGATCTAATTGAGATCGATAAGACGTCGGAGACGTCAAAGCTGCAGCAGCTGGTGGATAACATTGAGAACAAACTGACGGATCCAAATCAGTGCATCTTCTGTCAGAAGGTCATGTCCTGCCGCAGTTCGCTTCAGATGCACATACGCACCCATACGGGAGAGAGACCGTTCCGCTGCAAGATCTGTGGACGCGCCTTTGCCACCAAGGGAAACCTAAAGGCTCACATGAGCATCCACAAGATCAAACCGCCTATGCGAAGTCAGTTCAAGTGTCCGGTGTGTCACCAGAAGTTCTCCAACGGCATCATCCTGCAGCAGCACATACGCATCCACACCATGGACGATGGCAGCGGTGGTCAGGGTCAGAGCATCGGAGCTGGCGACGTGGATCGCTTGGGTATTGAGGATCAGAACTCCAACAAGTCGTTGGGCACCTCGGATACCCTGGACTTCTCCACTACTATTTCCGATCACTCGGGACAGCGCTCGGAATCCTCGCAGGGTGGAGACTTCGATGAGTTCATGACCATGGACAGCACTGACGATTCACGGGACAATTCAAGTGCTGCCACAGCCACGCCCTTGGacagagaaagggagagagacagACGACCTGCCGCCCACGATTGCTGCGATGAACGCTCCAGATCAGATCTGGAGGGCGGTGGACGTGAGAGCGCCTGCGGTGGTGAGTTACCCCCCATGGATCTCTCATCTCCATCGTCGGCGGCGGCTGCAGCGCGTCTCTTTGGTGTCACCAATGGCTCTGGAGCTGGAGGTCTGCCCATGCTCGGCATGCCCCTGCCCCCGAATCTGCTACTGATGGCGGCGGCACGAGAGGAGATGCATGCTCTGGGCCAGGCACATGCCAAGTTTCCGCTATTGCCCTTCGGACCGCTTGGATTTATGGGTCTGCAACCGCCCCCAAATGTGTGCAACTTATGCTTCAAGATGCTGCCTAGCCTGGCCGCCTTGGAGAGTCATCTACAGAGCGAACATGCCAAAGAAGCCACGATTTCATCGGGCCGAACCCAAAATAACGAGGCGGTATCACCCTACGGAGCCAAGCTCACTCTCAATCCAAATCTGTTTGCCAAGAAACCGAAGCCGGCACAGGAGATGACATTGGCGCCATCGGAGCCTGTTGCCCCAACGGCGGCACCTATCAAAGAGGAGCCCGAGTCCGAGCAGCTGTTGTCCGAGGAGGCAGGCTGCGAGGGAAGTGCTGCAGGtggcagcaacaccaacagcttTCCACAGGAAACCACAACCGATGCGGAGCAGTCGCTGATGAAGATGCAGCTCCATGCACATCGCTTTCCTGCGAGTCCGCTCGACTTTCAACAGGCTCTGATGTCGGCTGGTCCGCCCAGCTCCAGTCTCGATCCTCCGATAAACAACAAGCACTTCTGCCATGTGTGTCGACGCAACTTCAGCTCCAGCTCCGCACTGCAGATCCACATGAGAACACACACCGGGGACAAGCCTTTCCAGTGCAATGTGTGTCAGAAGGCCTTCACCACCAAGGGTAACCTCAAGGTTCATATGGGCACTCACATGTGGACGAATCCCACTTCACGGCGTGGTCGTCGCATGTCCTTGGAATTGCCCATGAGACCTGGTCCTGGACCGACTGGTCCGCCGACTGCCGAACAGGAGTTCATGCAGCGTCGACCTGAGCTCTTCTTTCCCTATTTGCCAACTTTCTTTAATGGAATGCCGCCAAAGCCTGGAGAACTGAGTCCTGGTGCCTTTGGGAACATTCCGCCACCGCATTTTGCCAACGGAGCAAAGTATCCATATCCACCTGGACTGCTTAGTTTTCCAGGCTTTCTCGGTGCTGGTCAACAGCCGCATCCGTATGCCATGGAGCGACGAGGTGACAGTAAATCCCCAATGTCGGATCCGGCACAAAGTCCGCCATCGCGTGAGGATGAGGGAAGCTTAGGAAATAATATTTGGCATCCGTTGAGTAGCATTAAGATGGAGAACAATCAAAACGAGAGCACTGGCAATCAGAGCGAAATGGAGCAGGATCCGGAGCAGGAGGACAATGAAGATGGAGATGCAGACGTTGATCCCGAGGGGGCGGATGTTGAAGAGTCGGAGGCGAGGAGCGGCGACATTTGTTGTGCCACGCGTATCCCATTCATCATACTTACCATTCCCCCCGTTCGAGGCACGCTCCTGTACCGCCTGCTGACTCCGACAATTGGATTGGAATCCATCGAACATATGCTGAATCTGGCACTAACTAGCCCCAGACTGAGGCAGTCTTCCATGCCGCAGCTCAACAGCTTTAAGGCGACccacgacgatgatgatgatgatgatgagaacGGCGGCACGAAATGGCGACCGATGACGGGGATGTCGCTGATATGGCCGTTGTCTCtcgatgtggatgtggatgtcgATGTGGATGTCGATGTCGAAGTCGATGTTGATGATTATTGTAGTTCAATATTTGCCTTATGGAAGGAGGCCTCAACTGTGTAG
- Protein Sequence
- MCSIFRNRINYRGTGTRSGASGGGTAPTNERESLLAKELNADSNNNGSGVEEVPQLHPDADADADAGAELQLEASLETSLPGNSEQQPENSNEALDLSVISGNRLPTSGHVALEALQHTKVAVAQFAATALAGAADPTDLAMVQSTIFNVQRQHLMQLQLIQHLQSQLKRAGGVVAALSRQGDPNEEEKDDLDEEEGEGEEEEEENPAKEQPMVNGEREAAEREQESLKTDGQDLSMEKAKECNKEMEKGKGRGMERDMDRERQREQVKRESEREIEAEVEPETENEYQPLMCDISSSLASSIITNHDPPPAPNEPNCLEMLQRRTEEVLDSASQSLHAAQMQEEYSEYASKEAQSRGEIFKHRCKYCGKIFGSYSALQIHLRSHTGERPFHCNVCGSKFTTKGNLKVHYQRHTQIFPPMLLPPVVNGAGPSGPSPEQFAALTPIRLPFVPPAPLAPPPPPSRDPPAAEQPQSQPPPPPQQQPPQQQQEQQVPQQAEDLSKPMRERSNSPVEREATPIKSLPDRSRVVTEPDQASPEKQEKERPKDSPKPTTPTASNRRNGSVRKRQTSNAGSPPGEERSADHAEHLHIAKLVRRSSASRDGSVGMPVAGEYSLAQMERIIDKSWEDLIEIDKTSETSKLQQLVDNIENKLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRCKICGRAFATKGNLKAHMSIHKIKPPMRSQFKCPVCHQKFSNGIILQQHIRIHTMDDGSGGQGQSIGAGDVDRLGIEDQNSNKSLGTSDTLDFSTTISDHSGQRSESSQGGDFDEFMTMDSTDDSRDNSSAATATPLDRERERDRRPAAHDCCDERSRSDLEGGGRESACGGELPPMDLSSPSSAAAAARLFGVTNGSGAGGLPMLGMPLPPNLLLMAAAREEMHALGQAHAKFPLLPFGPLGFMGLQPPPNVCNLCFKMLPSLAALESHLQSEHAKEATISSGRTQNNEAVSPYGAKLTLNPNLFAKKPKPAQEMTLAPSEPVAPTAAPIKEEPESEQLLSEEAGCEGSAAGGSNTNSFPQETTTDAEQSLMKMQLHAHRFPASPLDFQQALMSAGPPSSSLDPPINNKHFCHVCRRNFSSSSALQIHMRTHTGDKPFQCNVCQKAFTTKGNLKVHMGTHMWTNPTSRRGRRMSLELPMRPGPGPTGPPTAEQEFMQRRPELFFPYLPTFFNGMPPKPGELSPGAFGNIPPPHFANGAKYPYPPGLLSFPGFLGAGQQPHPYAMERRGDSKSPMSDPAQSPPSREDEGSLGNNIWHPLSSIKMENNQNESTGNQSEMEQDPEQEDNEDGDADVDPEGADVEESEARSGDICCATRIPFIILTIPPVRGTLLYRLLTPTIGLESIEHMLNLALTSPRLRQSSMPQLNSFKATHDDDDDDDENGGTKWRPMTGMSLIWPLSLDVDVDVDVDVDVEVDVDDYCSSIFALWKEASTV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00608619;
- 90% Identity
- iTF_00529003; iTF_00602000; iTF_00534017; iTF_00507058; iTF_00523128;
- 80% Identity
- -