Basic Information

Insect: Drosophila phalerata
Gene Symbol: zfh1
Assembly: GCA_951394115.2
Location: OX596005.2:29953423-29957755[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.9e-05 0.0028 18.5 1.0 1 23 149 171 149 171 0.97

2 15 0.00089 0.088 13.8 1.2 3 23 179 199 177 199 0.94

3 15 9.7e-05 0.0095 16.9 0.1 1 23 366 388 366 388 0.98

4 15 0.0009 0.089 13.8 2.2 1 23 394 416 394 416 0.98

5 15 3.7e-05 0.0036 18.2 2.2 1 23 447 470 447 470 0.95

6 15 0.00015 0.015 16.3 0.5 1 23 500 522 500 522 0.95

7 15 0.012 1.1 10.3 1.3 1 23 528 551 528 551 0.97

8 15 0.028 2.8 9.1 0.4 3 19 560 576 559 577 0.95

9 15 0.00017 0.017 16.1 5.6 1 23 586 608 586 608 0.97

10 15 0.044 4.3 8.5 1.2 2 23 614 635 613 635 0.96

11 15 9.8e-06 0.00097 20.0 1.0 1 23 644 666 644 666 0.98

12 15 0.0011 0.11 13.5 0.1 3 23 674 694 672 694 0.97

13 15 6e-05 0.0059 17.5 0.5 1 23 700 722 700 723 0.95

14 15 0.12 12 7.1 0.4 1 23 733 755 733 755 0.97

15 15 0.0032 0.31 12.1 0.1 1 23 1293 1315 1293 1315 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.9e-05	0.0028	18.5	1.0	1	23	149	171	149	171	0.97
2	15	0.00089	0.088	13.8	1.2	3	23	179	199	177	199	0.94
3	15	9.7e-05	0.0095	16.9	0.1	1	23	366	388	366	388	0.98
4	15	0.0009	0.089	13.8	2.2	1	23	394	416	394	416	0.98
5	15	3.7e-05	0.0036	18.2	2.2	1	23	447	470	447	470	0.95
6	15	0.00015	0.015	16.3	0.5	1	23	500	522	500	522	0.95
7	15	0.012	1.1	10.3	1.3	1	23	528	551	528	551	0.97
8	15	0.028	2.8	9.1	0.4	3	19	560	576	559	577	0.95
9	15	0.00017	0.017	16.1	5.6	1	23	586	608	586	608	0.97
10	15	0.044	4.3	8.5	1.2	2	23	614	635	613	635	0.96
11	15	9.8e-06	0.00097	20.0	1.0	1	23	644	666	644	666	0.98
12	15	0.0011	0.11	13.5	0.1	3	23	674	694	672	694	0.97
13	15	6e-05	0.0059	17.5	0.5	1	23	700	722	700	723	0.95
14	15	0.12	12	7.1	0.4	1	23	733	755	733	755	0.97
15	15	0.0032	0.31	12.1	0.1	1	23	1293	1315	1293	1315	0.97

Sequence Information

Coding Sequence: ATGAACAATCAGGATTATGGCGGCATCCAATGGATACAGCAGCACGCATCTGCAGTTGACTCCGAGTCCGATATGCTGGAAAGTGGAGCGGGGGACAGTGAGGTGACTGCGGCGTATCTGGTGAATGGCAACGCCACCGACGAGGATCTCGACCATATGGCGGCCGAGAATCTCATCTTTATGGCGCGAGATGGCCAACTGAGCGAGATTATAGCGGCCAATGAATCGGGAGGCGGCACAGTTCTAATCACGGACAGCGGCGTCGCTTACGCCGAGTCCTTTGATGATGACGCACAGGTGGTCACCGAGGAGATTATCACCGACGATTGGGTGCAGCACCAAGGCGCCGAACGTGTCGAAATCGCTGCAGAGCAAATTGCAGGCAATGTCAATTCGCTGGAGCTACTGGATATGGAGCAGGATGAGTATACGGCACTGCGTCCATATCCTTGTGATTTCTGTAGCCGGCGATTCCGCAAGAAGGCAAGCCTCAACAATCACATGCTGGCCCATCAGAACGATCGTCCGCATCTCTGTAAATTGTGCGGTGCACGATTCTCACGTCGCGCGGAGCTCATCAGTCACTTCAAGGCACATGCCGAGGCACAGGATGCAGCGGATGCGGAAGCTGCAGCGGCGGcttcaattaaatttgagccacagccacagcaCAGACAAGTGGATGATCATTTCTACGAACAGGAATGGCCTTTGTATCAGGATCAGGAGCACGAACAAatgcaggagcagcagcagcaactggaacaggagcagcagcaggagcagttAAACGTTGCCAGCCAGGTGTTGCAACAGGCGAGCTATGCAGCCGTGTCAGATGTTCCGGCTCCAACAGCTGCTCGAGGTCGCATCAGTCGCCTCAAGCCCAAAGAGGAGAGCACTCAATATATTGTGATTGCTGAGAAGCAGACAACGGACGACTTGCAACAGTTTGTGGACTGTGAGGAGTTGGCGCCTCCGGCACCACTGACCAATACCAATACTAATCCCAATGCAACGTCAACTCAATGCGATGCCAACAGCTCAACAGAGAACAATGCATCACGTTTCCCAGTGCTGGATGAGAGCAAGCCGTTTGTGTGTCAACAATGTGGATTGGCATTTGCACGGGAGAAGGCGCTTGTCTCCCATATCAAGAATCATCGCGTGGACTCGCCGTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGATAATCACAGCTTGCAGGAGCATCAGAAGACCCATCAGTTCGAGGAGAGCAATTCAGAGTACGATCCTGCCTCGGCGGGAGATGACAGTGCCAGCGAATCGGAGCCGGATCAGCTCTATGGTGACTTCTATTGCAGTGAGTGCGGCATCTCATTTCACAGACAGGATCTGCTCCGTCGTCATGCCAAGCAGCAGCATAAAACAGTCAACTCTGTCGATGTGGAGGGCAGTGCAGATCTGGAGGCAGATGCAGATGGTGATACCGATAATACCAAAGATGCGCCGCATTCATGTCACACGTGTGGCAAGTCATTTCCCAGCGCATTGGAGCTGCTCGCCCATGCCGAGATTCATGCCCGTTTCCCGCCATTCAAATGTGTCTTGTGCGGCATTAGCTTTTACGAGGAACAGGCCATTAAAAGGCATTTGCACACACGTCATCCGCACGAGCTGAAGCTTAACTCGTGTGTGCTCTGTGGCAAGGAGTGTCGGGATCGCAAGGCGCTGATTAAACATGCCTGGGATCATTCCCGTGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTCCACAACAAGGCGCGTCTGAAGCGACACATGGCCTCGCATCGTGACAAGTCGGTGGTGTGCGAGGTGTGCCACGAGGAGTTCCCCGACGGACGCACCCTTTCCAATCATCGTCATTCGCATAGCACCACATCGCCGGGCAAACTGTTCCCCTGCCATGAATGCGGCAAGACCTTTGGTTCCCGCAGCTCACAGCAGATACATGTGCGCATCCATACGGGCGAACGGCCCTATGGATGTCGGTACTGCTGGAAGGCCTTTGCGGATGGAGGTACGCTGCGCAAGCACGAAAGGATTCACACTGGCGAGAAGCCATATGCCTGTTCCGTCTGTCCGCGTGCGTTTAATCAGCGTGTTGTGCTGAGGGAACACATACGCTCCCATCATTCGGGATTGGATGCAGTGCGTGGCACGTATCATTGCACCGTCTGCACCGCGGATTTAAACTCATCCAATGAGCTTATACAGCATCTCATCCAACACAGCGACACGAACACAGCCAAACAACGACAACCAATTACTGGTCCCCGCAAATACAAACGTCGAAGGAAACTGCAGCCTCATGAAATTGCACACATGCGTGCTGAGCACAAGGATGGTGATGGCGATGCTGATGGCGATGCTGATGGCGATGATTATGTCAGTGACATGGATCTCTGCGATCTGGATGTGGAAAATGTGGACGATCTGTTTGACGCGGCGGAAACAACGCCGCCCAAAAAGGAAAAGCGCAAACGGAATGCTGCCAGTCAAGGAAAACCAGTGTCAAATGGCGTCTCAACATCCGCACTGAACAACAATACAACTGCATCAGCTAAATCCGCCAATGGGAATCCGGATCGCCTGTGGGAGGAGAAATTCCTGCAGGCAAATGGCAATGGAAATGCCGGCAATCAGTTGAATGATGATGCATTCAAGAGCTTCTTTCAAATTGACTCCTTGGTGGTGGTTAATGATACCACGCTGCAACCTATAAGCTCATCCAGTGTTGTCAGTGCGCCCAAGACACGGCGTAGTGCCAAACACACGCCACATTTGCCGAcgggcaacagcaacaacaagtccacaacaacagcagcaacaacaacagcagctggtGATGATTGTAGCAAGTCCAGTGCCTCTGTATCATCAAGCAGTCGAAGCAGCCGTAAGAAAACAGCCAAGTCTACCAAGAACTCGGCCAGCACGTCGTCCACTTCGAGCAGCTCGCGTCCAAGGATGATACACACGGAAAAGTCACGTGTGCCGCCAGAGAATGCCTCGAAGAGGACACGAGGAAGGTCCTATGTGACAAGGACGAGCACCAGCGAGAGCAGCCAGCTGGGTCTGGCCAAGTCACGCATTGTGGACGACTATGAGATAATATCACCTGCCACACAGCCACCGAATCAGATCAGCTCCAGTCCGTTGCACATCAagcaggaacaggagcagcagcaacagcgggTGCCACTCATGTATGATGATACGCATCTGTTGATAGATGCGGCCTTGTTGCGTGAGAAGACCTATGAGAAGTTCAATCCCAGCATTGTCAATGATCTGGAGGAGATACTGCGCAGTCCACTGAAGCATGATCGCAATTCGCGTCTGCGTTTCACCAGCGAATCATCGACAACGCCACAGTTTCTGCCCGAGGAAGAGCAGAATCTGATCAAAATCGAGCCAACGTCACCGGATTTGCGGGAAATGGTGGAGAGTCAGCAGCGTATCAGCTCCACAGGACATGCAACCACAccctcatcatcatcctcgTCAGCGGCACGAACTTCACGCCATCTGCGACAGCTCACTGCCAATTCCAGTTCACGGGCAGCATCAAAacgccacagcagcaacaaaacagTTTCCGCCTCCAGCTCCAAGAAATCCGCATCATCCGGATCATCTGGATCCGTTGCCGTGAGCAAAACCAACTCGTACCTCAGCTATGGCGTTGACTCCTACAATGTGAGTGTTGCTGCCAACACCAACTCTTCGGATGTCAGCTCGGGATTCTTCTCAATCTCGGAGGTCGTGTCCGCTGCAGATGCCGCCGATGCAGCCGCCAAAGCGGCAGCGGCCAATAAACCGGAACGTCGAGCCCGTTGCTATGAGTGTGAAATGTGCTCGGCCAATTTTCCGGATCGAGCTCAGCTTTTAGAGCATGTGCATATACACATCTGA
Protein Sequence: MNNQDYGGIQWIQQHASAVDSESDMLESGAGDSEVTAAYLVNGNATDEDLDHMAAENLIFMARDGQLSEIIAANESGGGTVLITDSGVAYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNVNSLELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAASIKFEPQPQHRQVDDHFYEQEWPLYQDQEHEQMQEQQQQLEQEQQQEQLNVASQVLQQASYAAVSDVPAPTAARGRISRLKPKEESTQYIVIAEKQTTDDLQQFVDCEELAPPAPLTNTNTNPNATSTQCDANSSTENNASRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNHSLQEHQKTHQFEESNSEYDPASAGDDSASESEPDQLYGDFYCSECGISFHRQDLLRRHAKQQHKTVNSVDVEGSADLEADADGDTDNTKDAPHSCHTCGKSFPSALELLAHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPHELKLNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCTADLNSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKDGDGDADGDADGDDYVSDMDLCDLDVENVDDLFDAAETTPPKKEKRKRNAASQGKPVSNGVSTSALNNNTTASAKSANGNPDRLWEEKFLQANGNGNAGNQLNDDAFKSFFQIDSLVVVNDTTLQPISSSSVVSAPKTRRSAKHTPHLPTGNSNNKSTTTAATTTAAGDDCSKSSASVSSSSRSSRKKTAKSTKNSASTSSTSSSSRPRMIHTEKSRVPPENASKRTRGRSYVTRTSTSESSQLGLAKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQQQQRVPLMYDDTHLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHDRNSRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRISSTGHATTPSSSSSSAARTSRHLRQLTANSSSRAASKRHSSNKTVSASSSKKSASSGSSGSVAVSKTNSYLSYGVDSYNVSVAANTNSSDVSSGFFSISEVVSAADAADAAAKAAAANKPERRARCYECEMCSANFPDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00579414;
90% Identity: iTF_00507028; iTF_00523097;
80% Identity: -