Basic Information

Insect: Drosophila falleni
Gene Symbol: zfh1
Assembly: GCA_035045575.1
Location: JAWNOV010000062.1:11180259-11184606[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.9e-05 0.0022 18.5 1.0 1 23 149 171 149 171 0.97

2 15 0.00089 0.066 13.8 1.2 3 23 179 199 177 199 0.94

3 15 9.6e-05 0.0072 16.9 0.1 1 23 363 385 363 385 0.98

4 15 0.0009 0.067 13.8 2.2 1 23 391 413 391 413 0.98

5 15 3.6e-05 0.0027 18.2 2.2 1 23 444 467 444 467 0.95

6 15 0.00015 0.011 16.3 0.5 1 23 502 524 502 524 0.95

7 15 0.012 0.86 10.3 1.3 1 23 530 553 530 553 0.97

8 15 0.012 0.9 10.3 0.9 1 19 560 578 560 579 0.95

9 15 0.00017 0.013 16.1 5.6 1 23 588 610 588 610 0.97

10 15 0.044 3.3 8.5 1.2 2 23 616 637 615 637 0.96

11 15 9.8e-06 0.00073 20.0 1.0 1 23 646 668 646 668 0.98

12 15 0.0011 0.083 13.5 0.1 3 23 676 696 674 696 0.97

13 15 6e-05 0.0045 17.5 0.5 1 23 702 724 702 725 0.95

14 15 0.055 4.1 8.2 0.4 1 23 735 757 735 757 0.97

15 15 0.0032 0.24 12.1 0.1 1 23 1297 1319 1297 1319 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.9e-05	0.0022	18.5	1.0	1	23	149	171	149	171	0.97
2	15	0.00089	0.066	13.8	1.2	3	23	179	199	177	199	0.94
3	15	9.6e-05	0.0072	16.9	0.1	1	23	363	385	363	385	0.98
4	15	0.0009	0.067	13.8	2.2	1	23	391	413	391	413	0.98
5	15	3.6e-05	0.0027	18.2	2.2	1	23	444	467	444	467	0.95
6	15	0.00015	0.011	16.3	0.5	1	23	502	524	502	524	0.95
7	15	0.012	0.86	10.3	1.3	1	23	530	553	530	553	0.97
8	15	0.012	0.9	10.3	0.9	1	19	560	578	560	579	0.95
9	15	0.00017	0.013	16.1	5.6	1	23	588	610	588	610	0.97
10	15	0.044	3.3	8.5	1.2	2	23	616	637	615	637	0.96
11	15	9.8e-06	0.00073	20.0	1.0	1	23	646	668	646	668	0.98
12	15	0.0011	0.083	13.5	0.1	3	23	676	696	674	696	0.97
13	15	6e-05	0.0045	17.5	0.5	1	23	702	724	702	725	0.95
14	15	0.055	4.1	8.2	0.4	1	23	735	757	735	757	0.97
15	15	0.0032	0.24	12.1	0.1	1	23	1297	1319	1297	1319	0.97

Sequence Information

Coding Sequence: ATGAACAATCAGGATTATGGCGGCATCCAATGGATACAGCAGCACGCATCTGCGGTCGACTCCGAGTCCGATATGCTGGAAAACGGGGCTGGCGACAGTGAGGTGACTGCGGCCTATTTAGTGAATGGCAACGCCACCGACGAGGATCTCGACCATATGGCGGCCGAGAATCTCATCTTTATGGCGCGAGATGGCCAGCTGAGCGAGATTATAGCTGCCAACGAATCGGGTGGCGGCACAGTTCTAATCACTGACAGCGGCGTCGCATATGCGGAGTCATTCGATGATGACGCACAGGTGGTCACCGAGGAGATCATTACCGATGATTGGGTGCAGCATCAAGGCGCCGAACGTGTCGAAATCGCTGCTGAGCAAATTGCAGGAAATGTCAATTCGCTGGAGCTACTGGATATGGAGCAGGATGAGTATACGGCCCTGCGTCCCTATCCTTGTGATTTCTGTAGCCGGCGATTCCGCAAGAAGGCAAGCCTCAACAATCACATGCTGGCACATCAAAACGATCGTCCGCATCTGTGTAAATTGTGCGGAGCACGATTCTCTCGTCGCGCCGAGCTCATCAGTCACTTTAAGGCACATGCCGAGGCGCAGGATGCAGCCGATGCGGAGGCTGCAGCGGCggcttcaattaaatttgagcCACCGCAGCACAGACAAGTGGATGATCATTTCTACGAACAGGAATGGCCATTGTATCAGGATCAGGAGCACGAACAAAtacaggagcagcagcagcagcaacaacaactggagcaggaacaggaacagttAACCGTTGCCAGCCAGGTGATGCAACAGGCCAGCTACGCAGCAGTGTCAGATGTGGCCGCACCTACAGCTGCTCGGGGTCGCATAAGTCGCCTCAAGCCCAAGGAGGAGAGCACGCAGTATATTGTGATTGCTGAGAAGCATACAACTGACGACTTGCCACAGTTTGTGGACTGTGAGGAGTTGGCGCCACCGCCACCACTGTCCAATACTAATGTCAATGTAACGTCAACTCAAAGCGATGCCAACAGCTCAGCAGAAAATGCATCACGTTTCCCAGTGCTGGATGAGAGCAAACCCTTTGTATGTCAACAATGTGGATTGGCATTTGCACGGGAGAAGGCGCTTGTCTCCCATATCAAGAATCATCGCGTGGACTCGCCGTTTGAGTGTAATCAGTGCCAGGAGATGTTCTGGGACAATCACAGCCTGCAGGAGCATCAGAAGACACATCAGTTCGAGGAGAGCAATTCAGAGTACGATCCTGCTTCGGCGGGAGATGACAGTGCCAGCGAATCGGAGCCAGATCAGCTCTATGGTGACTTCTATTGCAGTGAGTGCGGCATCTCATTTCACAGGCAAGATCTGCTCCGTCGTCATGCAAAGCAGCAGCATAAATTGGGCGTGGCCTCGACAGTCAACTCTGTCGATGTGGAGGGCAGTGCAGATCtggatgcagatgcagatggTGATACCGATAATACCAAAGATGCGCCGCATTCTTGCCACACGTGTGGCAAGTCATTTCCCAGCGCATTGGAGCTGCTCGCCCATGCTGAGATTCATGCCCGTTTCCCGCCATTCAAATGTGTCTTGTGCGGCATTAGCTTTTACGAGGAACAGGCCATTAAAAGGCATTTGCACACTCGTCATTCGCACGAGCTGAAGCAACATTCATGTGTGCTCTGTGGCAAGGAGTGTCGGGATCGCAAGGCGTTGATTAAACACGCCTGGGATCATTCCCGTGAGAAGTGCCACTCGTGCTCCAAGTGCGGCAAGAACTTCCACAACAAGGCGCGTCTGAAGCGACACATGGCCTCGCATCGTGATAAGTCGGTGGTGTGCGAGGTGTGCCACGAGGAGTTCCCCGACGGACGCACCCTTTCCAATCATCGTCATTCGCATAGCACCACGTCGCCGGGCAAACTGTTTCCCTGCCATGAATGCGGCAAGACCTTTGGCTCCCGCAGCTCACAGCAGATACATGTGCGCATCCACACGGGCGAACGACCCTATGGATGTCGGTATTGCTGGAAGGCCTTTGCCGATGGAGGTACGCTGCGCAAGCACGAAAGGATTCACACTGGCGAGAAGCCATATGCCTGCTCCGTCTGTCCGCGTGCGTTTAATCAGCGTGTTGTGCTCAGGGAACACATACGCTCCCATCATTCGGGACTGGATGCAGTGCGTGGAACGTATCATTGCACCGTCTGCACAGCGGATTTATCCTCATCCAATGAGCTTATACAGCATCTCATTCAACACAGCGACACGAACACAGCCAAGCAACGACAACCAATTACGGGTCCCCGCAAATACAAGCGTCGAAGGAAACTGCAGCCTCATGAAATCGCACACATGCGTGCTGAGAACAAGGATGGCGATGGtgatggcgatggcgatggcgatgatTATGTCAGTGACATGGATCTCTGCGATCTGGATGTGGAGAATGTGGACGATCTCTTTGACGCGGCAGAAACAACGCCACCCAAAAAGGAGAAGCGCAAACGGAATGCCGCCAGTCAAGGGAAACCAGTGTCAAATGGCGTCTCAACATCCGCGCTAAATAACAATACAACTCCATCAGCCAAATCCGCCAATGGGAATCCGGATCGCTTGTGGGAGGAGAAATTTCTGCAGGCAAATGGAAATGGTAATGCCGGCAATCAGTTGAATGATGATGCGTTTAAAAGCTTCTTTCAAATTGACTCTTTGGTGGTGGTTAACGATACCACGTTGCAACCTATAAGCTCATCCAGTGTTGTCACTGCGCCCAAGACACGACGTAGTGCCAAGCAGACGCCACAGTTGCCGacgagcaacagcaacaagtcaacaacaaccacaacagcagcagcaacaacaacaacaactggtgAAGATGGTAGCAAGTCCAGTGCCTCAGTATCGTCAAGCAGTCGCAGCAGCCGTAAGAAATCAGCCAAGTCCACTAAGAACTCGACCAACACATCGTCCACTGCGAGCAGCTCGCGTCCAAGGATGATACATACGGAGAAGTCACGTGTGCCGCCGGAGAATGTTTCGAAGAAGACACGCGGAAGGTCCTATGTGACGAGGACGAGCACCAGCGAGAGCAGCCAGCTGGGTCTGGCTAAGTCACGTATTGTGGACGACTATGAGATAATATCACCTGCCACACAGCCACCGAATCAGATAAGCTCCAGTCCGTTGCACATCaagcaggaacaggagcagcagcaacaacgtgTGCCACTCATGTATGATGATACGCATCTGTTGATCGATGCGGCTTTGTTGCGTGAGAAGACCTATGAGAAGTTCAATCCCAGCATTGTCAATGATCTGGAGGAGATTCTACGTAGTCCACTCAAGCATGATCGCAATTCACGTCTGCGTTTCACCAGCGAATCATCGACAACGCCACAGTTCCTGCCCGAGGAGGAGCAGaatctaattaaaatagagCCAACGTCACCCGATTTGCGTGAAATGGTGGAGAGTCAGCAGCGTGTGAGCTCCACGGGACATGCAACCACAccctcatcatcatcctcgtcAGCGGCGCGAACTTCACGACACCTGCGACAGCTCACTGCCAATTCCAGTTCACGGGCGGGAACGAAAcgacacagcagcagcagcagcagtaacaaaaCAGTTTCCGCATCCAGCTCCAAGAAATCTGCATCATCCGGATCATCCGTTGCTGTGAGCAAAGCCAACTCGTACCTCAGCTATGGCGTGGACTCCTACAATGTGAGTGTTGCTGCCAATGCCAACTCATCGGATGTCAGCTCTGGATTCTTCTCCATCTCGGAGGTTGTGTCCGCTGCAGATGCCGCCGATGCAGCCGCCAAAGCGGCAGCGGCCAATAAGCCGGAGCGTCGTGCCCGTTGCTATGAGTGCGAAATGTGCTCAGCCAATTTTCCGGATCGAGCTCAGCTGCTGGAGCATGTGCATATACACATCTGA
Protein Sequence: MNNQDYGGIQWIQQHASAVDSESDMLENGAGDSEVTAAYLVNGNATDEDLDHMAAENLIFMARDGQLSEIIAANESGGGTVLITDSGVAYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNVNSLELLDMEQDEYTALRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAASIKFEPPQHRQVDDHFYEQEWPLYQDQEHEQIQEQQQQQQQLEQEQEQLTVASQVMQQASYAAVSDVAAPTAARGRISRLKPKEESTQYIVIAEKHTTDDLPQFVDCEELAPPPPLSNTNVNVTSTQSDANSSAENASRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNHSLQEHQKTHQFEESNSEYDPASAGDDSASESEPDQLYGDFYCSECGISFHRQDLLRRHAKQQHKLGVASTVNSVDVEGSADLDADADGDTDNTKDAPHSCHTCGKSFPSALELLAHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHSHELKQHSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAVRGTYHCTVCTADLSSSNELIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAENKDGDGDGDGDGDDYVSDMDLCDLDVENVDDLFDAAETTPPKKEKRKRNAASQGKPVSNGVSTSALNNNTTPSAKSANGNPDRLWEEKFLQANGNGNAGNQLNDDAFKSFFQIDSLVVVNDTTLQPISSSSVVTAPKTRRSAKQTPQLPTSNSNKSTTTTTAAATTTTTGEDGSKSSASVSSSSRSSRKKSAKSTKNSTNTSSTASSSRPRMIHTEKSRVPPENVSKKTRGRSYVTRTSTSESSQLGLAKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEQQQQRVPLMYDDTHLLIDAALLREKTYEKFNPSIVNDLEEILRSPLKHDRNSRLRFTSESSTTPQFLPEEEQNLIKIEPTSPDLREMVESQQRVSSTGHATTPSSSSSSAARTSRHLRQLTANSSSRAGTKRHSSSSSSNKTVSASSSKKSASSGSSVAVSKANSYLSYGVDSYNVSVAANANSSDVSSGFFSISEVVSAADAADAAAKAAAANKPERRARCYECEMCSANFPDRAQLLEHVHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00579414;
90% Identity: iTF_00575748;
80% Identity: -