Basic Information

Insect: Drosophila percnosoma
Gene Symbol: zfh1
Assembly: GCA_035043855.1
Location: JAWNMQ010000651.1:201713-206270[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.2e-05 0.0014 18.9 1.3 1 23 152 174 152 174 0.97

2 15 0.0009 0.059 13.8 1.2 3 23 182 202 180 202 0.94

3 15 9.8e-05 0.0064 16.9 0.1 1 23 378 400 378 400 0.98

4 15 0.00034 0.022 15.2 0.9 1 23 406 428 406 428 0.98

5 15 0.00012 0.0079 16.6 2.3 1 23 460 483 460 483 0.94

6 15 0.025 1.6 9.3 1.5 1 23 530 552 530 552 0.93

7 15 0.0026 0.17 12.4 0.4 1 23 558 581 558 581 0.98

8 15 0.029 1.9 9.1 0.4 3 19 590 606 589 607 0.95

9 15 0.00017 0.011 16.1 5.6 1 23 616 638 616 638 0.97

10 15 0.044 2.9 8.5 1.2 2 23 644 665 643 665 0.96

11 15 1e-05 0.00065 20.0 1.0 1 23 674 696 674 696 0.98

12 15 0.0011 0.074 13.5 0.1 3 23 704 724 702 724 0.97

13 15 6.1e-05 0.004 17.5 0.5 1 23 730 752 730 753 0.95

14 15 0.051 3.3 8.3 0.4 1 23 763 785 763 785 0.97

15 15 0.0087 0.57 10.7 0.6 1 23 1288 1310 1288 1310 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.2e-05	0.0014	18.9	1.3	1	23	152	174	152	174	0.97
2	15	0.0009	0.059	13.8	1.2	3	23	182	202	180	202	0.94
3	15	9.8e-05	0.0064	16.9	0.1	1	23	378	400	378	400	0.98
4	15	0.00034	0.022	15.2	0.9	1	23	406	428	406	428	0.98
5	15	0.00012	0.0079	16.6	2.3	1	23	460	483	460	483	0.94
6	15	0.025	1.6	9.3	1.5	1	23	530	552	530	552	0.93
7	15	0.0026	0.17	12.4	0.4	1	23	558	581	558	581	0.98
8	15	0.029	1.9	9.1	0.4	3	19	590	606	589	607	0.95
9	15	0.00017	0.011	16.1	5.6	1	23	616	638	616	638	0.97
10	15	0.044	2.9	8.5	1.2	2	23	644	665	643	665	0.96
11	15	1e-05	0.00065	20.0	1.0	1	23	674	696	674	696	0.98
12	15	0.0011	0.074	13.5	0.1	3	23	704	724	702	724	0.97
13	15	6.1e-05	0.004	17.5	0.5	1	23	730	752	730	753	0.95
14	15	0.051	3.3	8.3	0.4	1	23	763	785	763	785	0.97
15	15	0.0087	0.57	10.7	0.6	1	23	1288	1310	1288	1310	0.97

Sequence Information

Coding Sequence: ATGAACAATCCGGACTATGGCGGCATCCAGTGGATACAGCAGGAAAGCAGCGCCGTCGTCGACGACAGCGAAGCAGAGATGACGGCAGCCTATTTGGTCAACGCTGCCGCCAATGGAAGCATTTCCAACGATGACGAGCTCGATCATATTGCAGCCGAGAATCTCATCTTTATGGCACGCGACCGCCAACTGAGCGAAATCATCGCCGCAAGTGAGGCAAATGGCGGCAGCACCACAGTGCTAATCACGGAGAGAGACGGAAATAACGGACTGGAATACGCCGAGTCCTTTGACGATGATGCCCAAGTCGTCACCGAGGAGATCATCACGGATGACTGGGTCCAGCATCAGGGCGCAGAGCGtGTGGAAATTGCAGCAGAGCAAATCGCTGGCAACGGCAGCTCCCAGGAGCTGTTGGACATGcaacagaatatatatatttcgatgcGTCCATATCCCTGTGACTTTTGCAGTCGACGCTTTCGCAAGAAGGCCAGCCTCAACAATCATATGCAGGCGCATCAGAATGATCGTCCCCATCTCTGCAAACTGTGCGGGGCGCGTTTCTCGCGACGTGCGGAGCTCATCAGTCACTTCAAGGCGCATGCGGAGGCCCAGGTGGCCGCCGATGAAGAGGCAGCTGCGGCAGCCATTAAATTtgagccacaacagcagctgcaatcgctgcaacagcagcagcagcagcagcgacaaattGATGATCATTTCTATGAGCAGGAATGGCCGCTGTATCAGGAACATGAACAGGAGCAGatcgaggagcagcagctgcagcagatcgaggagcagcagcagcagcagctggaacagTTTCAGCAGCGGTTGCAACATTCGGTTGCACCACCAACCGCTGCTCGTGGACGTATCAGTCGATTGAAACTCAAGGAGGAGAGCTCCCAATATATTGTGATTGCCTCCGATAAAACGGAGGCGGAGTTGCCTCAATACATGCATTGCGAGGCGAATGGCGATCAATCACttgccaccaacaacagccaagTCCAATCAACATCATCCAATGATGTTgcaactgatgctgctgctgctgctgctgatggggCAGACGGGCAGGCAACGCTGCGCTTTCCCGTGCTCGACGAGAGCAAACCGTTCGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCGCTCGTCTCCCACATCAAGAATCATCGCGTGGATTCGCCCTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAATTACAGTCTGCAGGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAATTCGGAATATGAGCCCGCATCGGCGGGCGAGGAGGATACGGCGAGTGAATCGGAAGCGGAACAGCTTTACGGTAATTTCTACTGTGGAGAATGCGGCATCTCCTTTCACCGGCAGGATTTGTTGCGGCgacacagcaaacagcagcacagcaagcagctggctgcaacaacagctggtggcagcaacaacaacaacagtgtggcaactgcaacagcaacggatGCAATGGGTGCCGcagatgcaactgcaactgatgcCGATGCTGGTGATTCCAAAGATGCGACACATTGTTGCCGCACGTGCGGCAAATCATTTCCCAGCGTACTCAAACTGCTCGCCCATGCCGAAATCCACAAACGCTTCCCGCCATTCAAATGTGTGCTGTGCGGAATCAGCTTCTACGAGGAGCAGGCGATAAAGCGGCACCTGAACACGCGGCATCCGCACGAGCTGAAGCAAAATtcatgtgtgttgtgtggcaAGGAGTGTCGCGATCGGAAGGCGCTGATCAAACATGCGTGGGATCATTCGCGAGAGAAGTGCCACTCGTGCTCCAAGTGTGGCAAGAATTTCCACAACAAGGCGCGCCTGAAGCGACACATGGCATCGCATCGCGACAAGTCCGTCGTGTGCGAAGTGTGCCACGAGGAGTTCCCCGATGGACGCACTTTGTCCAATCATCGGCATTCCCACAGCACAACGTCGCCGGGCAAACTCTTTCCCTGCCACGAGTGTGGCAAGACTTTTGGGTCACGCAGCTCGCAACAGATTCATGTGCGCATCCACACGGGTGAAAGGCCCTACGGTTGTCGCTACTGCTGGAAGGCCTTCGCCGACGGCGGCACTCTCCGCAAACACGAACGCATCCATACGGGCGAGAAGCCCTATGCGTGCTCCGTCTGCCCGCGTGCCTTCAATCAGCGTGTGGTCTTGCGTGAACACATCCGGTCGCATCATTCCGGTCTGGATGCGGCACGTGGCACGTATCATTGCACGGTGTGCTCGGCGGATTTGAGCTCATCGAATGACCTCATCCAGCATCTCATCCAGCACAGTGATACGAACACAGCCAAGCAGCGACAGCCAATTACTGGCCCACGTAAATACAAACGTCGTCGGAAACTGCAGCCGCATGAGATTGCGCACATGCACGCCGAGCACAAGGCTGGCGGCGGCGATGGCGAGGCTGGCGAGGAGGAGGATTATGCCAGCGACTTGGACTACTGCCATCTGGATGTGGAGAATGTGGATGAACTGCTGCAGGAGGCAACGGCAGAGCCACCATCACCCGCCAAAAAAGCGAAACGCAAACGCAAAGCCCCAATTAAAACCGGTGATGAGCAAAGATTGTGGGCTGAGAAATTCCCGCAGCAGGCGAGCAATGGGAATAGCGATGAGGCCTACAAGAGTTTCTTCCAGATGGACTCAGTGGTCGTGGTCAATGATCAAACGTTGCAGCCCGTTGATGCTGGTGTTGCCTCGACCAAGTTGCAGCAGGCGGAGATTAAGGAGCAAACACTGAAGACAGGCAATCGCAGTAGCAAAAGAAGGGCAGGTAAAGCTGGGGGAGGAGGGGCAGGCGCAccaggaggagcaggagctgctgctactgctgctccaCGTCCCCGGATGATACACACGGCCAAGTCGCCGCAGACAACGGCAAGGAAATCCCGCACAAGGAGTTATGTCACACGCACCAGCAccaatgagcagcagcagggggaAGGAGCAAGTGGAGGAAGCCTCATCAAATCCCGGATTGTAGATGACTACGAGATCATCTCGCCGGCCACACAGCCACCCAATCAGATCAGCTCCAGTCCGCTGCACATCaaacaggagcaggaacatcaacagcatcatcatcatcagcatcagcagcagcaccagagaGTCCAATTGCTCTTCGATGACAGCCATCTGCTCATCGATGCGGGCCTGTTGCGTGAGAAGACCTACGAGAAATATAATCCCAGCATTGTCCAAGATCTCGAAGAGATTTTGCGTAGTCCCCCGAAGCATGAGCGGGACGATCGACGGCTGCGCTTCACCAGCGAATCGTCGACGACGCCACAATTTCTGCCcggcgaggaggaggaacagCATCTCATCAAGATCGAGCCCACGTCGCCGGATCTCCGCGAAATGGTCGAGagccagcagccagcggcACTGCCCACATCTTCCTCCGCCTGCTCAACGGCAGCACGCACTTCCCGCCACCTGCGACAACTGACTGCCAATGGTTCCAGTTCCATTTCCACTGCCACATCCAGTTCCAGTGGCGCTCCAAGTACGCGAGCCGCTTCCAAGCGCAATGCCAGCAAACAGCTTTCCAAGAAATCCActtccaacagcaacaaaggcaacGCTACATCGTCTTATCTCAGCTATGGCGTCGACTCCTAtaatgtgggcgtggcaaccaGTGCCAATAGCTCCTCGGATGTCAGTTCCGgtttcttttccatttccgAGGTCGTCTCGGCGGCGGATGCAGCCgatgcagctgcaacggcggcggcggcagcagccacGGAGCGAAGAACGCGCTGCTTTGAATGCGAAATGTGCTCGTCCTATTTCCCAGATCGCGCCCAGCTGCTGGAACACATGCACGAACACATCTAG
Protein Sequence: MNNPDYGGIQWIQQESSAVVDDSEAEMTAAYLVNAAANGSISNDDELDHIAAENLIFMARDRQLSEIIAASEANGGSTTVLITERDGNNGLEYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNIYISMRPYPCDFCSRRFRKKASLNNHMQAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQVAADEEAAAAAIKFEPQQQLQSLQQQQQQQRQIDDHFYEQEWPLYQEHEQEQIEEQQLQQIEEQQQQQLEQFQQRLQHSVAPPTAARGRISRLKLKEESSQYIVIASDKTEAELPQYMHCEANGDQSLATNNSQVQSTSSNDVATDAAAAAADGADGQATLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYEPASAGEEDTASESEAEQLYGNFYCGECGISFHRQDLLRRHSKQQHSKQLAATTAGGSNNNNSVATATATDAMGAADATATDADAGDSKDATHCCRTCGKSFPSVLKLLAHAEIHKRFPPFKCVLCGISFYEEQAIKRHLNTRHPHELKQNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAARGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMHAEHKAGGGDGEAGEEEDYASDLDYCHLDVENVDELLQEATAEPPSPAKKAKRKRKAPIKTGDEQRLWAEKFPQQASNGNSDEAYKSFFQMDSVVVVNDQTLQPVDAGVASTKLQQAEIKEQTLKTGNRSSKRRAGKAGGGGAGAPGGAGAAATAAPRPRMIHTAKSPQTTARKSRTRSYVTRTSTNEQQQGEGASGGSLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHHHHQHQQQHQRVQLLFDDSHLLIDAGLLREKTYEKYNPSIVQDLEEILRSPPKHERDDRRLRFTSESSTTPQFLPGEEEEQHLIKIEPTSPDLREMVESQQPAALPTSSSACSTAARTSRHLRQLTANGSSSISTATSSSSGAPSTRAASKRNASKQLSKKSTSNSNKGNATSSYLSYGVDSYNVGVATSANSSSDVSSGFFSISEVVSAADAADAAATAAAAAATERRTRCFECEMCSSYFPDRAQLLEHMHEHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00542584;
90% Identity: iTF_00499722;
80% Identity: -