Basic Information

Insect: Drosophila peninsularis
Gene Symbol: RREB1
Assembly: GCA_035047485.1
Location: JAWNPN010000042.1:3391180-3397320[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0055 0.37 11.3 0.6 1 21 240 260 240 262 0.96

2 13 0.00032 0.021 15.2 0.2 1 23 272 294 272 294 0.98

3 13 7.6e-05 0.0051 17.2 7.3 1 23 300 322 300 322 0.98

4 13 0.042 2.8 8.6 0.8 2 20 535 553 535 555 0.93

5 13 0.0083 0.55 10.8 0.1 1 23 704 726 704 726 0.97

6 13 1.2e-05 0.00077 19.8 0.7 1 23 736 758 736 758 0.99

7 13 0.00078 0.052 14.0 2.0 1 23 764 787 764 787 0.97

8 13 0.0028 0.19 12.3 2.0 1 23 1034 1057 1034 1057 0.95

9 13 8.1e-05 0.0054 17.1 0.3 2 23 1370 1391 1369 1391 0.97

10 13 0.14 9.1 7.0 6.3 1 23 1397 1420 1397 1420 0.97

11 13 3 2e+02 2.7 4.2 1 23 1536 1559 1536 1559 0.88

12 13 0.0079 0.53 10.8 0.5 3 23 1618 1638 1616 1638 0.96

13 13 0.0013 0.084 13.4 4.8 1 23 1644 1666 1644 1666 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0055	0.37	11.3	0.6	1	21	240	260	240	262	0.96
2	13	0.00032	0.021	15.2	0.2	1	23	272	294	272	294	0.98
3	13	7.6e-05	0.0051	17.2	7.3	1	23	300	322	300	322	0.98
4	13	0.042	2.8	8.6	0.8	2	20	535	553	535	555	0.93
5	13	0.0083	0.55	10.8	0.1	1	23	704	726	704	726	0.97
6	13	1.2e-05	0.00077	19.8	0.7	1	23	736	758	736	758	0.99
7	13	0.00078	0.052	14.0	2.0	1	23	764	787	764	787	0.97
8	13	0.0028	0.19	12.3	2.0	1	23	1034	1057	1034	1057	0.95
9	13	8.1e-05	0.0054	17.1	0.3	2	23	1370	1391	1369	1391	0.97
10	13	0.14	9.1	7.0	6.3	1	23	1397	1420	1397	1420	0.97
11	13	3	2e+02	2.7	4.2	1	23	1536	1559	1536	1559	0.88
12	13	0.0079	0.53	10.8	0.5	3	23	1618	1638	1616	1638	0.96
13	13	0.0013	0.084	13.4	4.8	1	23	1644	1666	1644	1666	0.99

Sequence Information

Coding Sequence: atgctggccacacagcagcaacagcaacagccgcctcaacagcaacatacagcagcaacagctgcagcgggAGTAGCTCTGGAGGATGCGGTCATGGAGCGGCAGCGTCGTGACTCCAGCACCTCGGAGTCTTCGCTGGAGCATCTGGATCTGGGCCGCACGCCAAAgaagctgagcagcagcagcggtgcGCCGCAgccgacgtcgacgccgcACGTTGAGGCCACTTCGCGGAAGCGCAAgatgcgacagcagcagcagccacagcagccgaTCTTGTACTCCGATGAGGAGgacgagcaacagcagcagcaacagcagcagcagcagcaacagctgctggagcagtCGGCGCATCGCATGCGCCACAAGCAGCGCCGCAGCGGCAatgcagtcgctgtcgctgccagcgccagcatcGTCGTCGACTACAGCGTCGGCAGTGATGCCAGCTCGCTGCGCAAGAAGTTCCGGCTGaaccgcagcagcatcagcgccCACAACGGCGACCTCTCCGAGTCGGGCTTCGTCGACGGCAGCGCCCACAGCGGCTACTTGctcagcgccagcagcgcgaCGCAGTCGGCGacggcagcgcagcagcagcagcaacagcagcagccgggcTCGGGCAGCAGCTCCGGCGGCTCCTCGCCCCAAGGCCTGTGCCATTCGAGCGCCGAGTCCGGCATCGGCGCCGGCGACGAGCACATGAAGTACGTCTGCCCCATCTGCGAGGTTGTCTCGGCCACGCCCCACGAGTTCACCAATCACATTCGATGCCACAACTATGCCAACGGCGACACCGAGAACTTCACCTGCCGCATTTGCTCCAAGGTACTCTCGTCGGCCTCCTCGCTGGACAGACACGTCCTGGTGCACACCGGGGAGCGACCCTTCAACTGTCGCTATTGCCACTTGACCTTCACGACAAATGGCAACATGCATCGCCACATGCGCACACAcaagcaacaccagcagcagcagcagcaacagcagcagcagcagcagcagcaaccacaacagcagcaagcccagacacagcagcagcagcagccgctgcagcagcagcaacagttgcagcgcCACCAGCAACATGCCGCAGGCAATGCCGTGGCTCAGCGCGCCGAGAGCTACGAGAGCGACGCCAGCTGCTCCACGGACatatccagcagcagcagcagcgcagccagcaacaacaacaacaacaacacaagccaagcgaacaacaacaacagcagccaggaggagcagcaactgttgctggcgtgcaagcagcagcagcagctgaagacaaacatcaacaacaacaacatcatcgtGAGCGACGAGCGAGCGCTGGACACGGACGGGGacggagaggcagaggcagacggGGCTGGGGACGAGGCCGAGAGCGTGGATGTGACCCAGATGATCACGAGCACGCCCGACGTGGCCACCCTGCTGGCGACGTCgtcgggcagcagcagcccgcgCACCCCGGAGCCCGAGGCGGCGGAGGGCctgctgcccagctgcccgGCCTGCAATGCCGACGGGTTCGAGACGCTGGCCGCGCTCTACGCCCACCTGGAGGCGGAGCACGCGGACATACCCGCCAAGTGCCGCGAGTGCGAGGTGATCTTCGCCacgcagcgccagctgcaggcgcACAGCTGCCgcgggctgcagctgccgccgctgctgggcGCCAGCTCCTCGCCGCTGCACAAGCAGGAGCcggcggaggaggaggacgaggagcagcagctgcgccagcacgaggctgaggcagaggccgacgaggacgaggacgagctgcggctgcaggCGAACAGCGAGCGGGACGAGTTCTTCCAGCAGCTGTACCTCAAGGGCAAGTCGGGCGGCTCCTCGCTGCCGTCGCCCATCAAGCACGAGCCGTCGGAGCAGCGCCAGGACCTGGCCGACATCCAGAGCATCCTGCAGAtgaccagctccagctgcacgTCCAGCTTCCTGCGCAACTTCGAGCAGAGCGTGAACACGCCCTGCTCCAGCCAGTACAGCCTGGACGGGCGCGAGGGCGAGGAGGAGGCCCAGGACGCCTTCACCAGCGAGTTCCGCCGCATGAAGCTGCGCGGCGAGTTCCCCTGCAAGCTCTGCTCCGCCGTCTTTCCCAACCTGCGCGCCCTCAAGGGCCACAACCGCGTCCACCTGGCGGCCGTCGGCGCCGCCGGCCCCTTCCGCTGCAACATGTGCCCCTACGCCGTCTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGGGACCGGCCGTACGAGTGCGCCGTCTGCAACTACGCCTTCACCACGAAGGCCAACTGCGAGCGGCACCTGCGCAACCGGCACGGCAAGACGAGCCGCGACGAGGTGAAGCGCGCCATCGTCTATCACCCGGCAGAGGACGCCAGCTGCGAGGACATCAAGCCCAAGATGGACCCGGATCTGTCCGAGCTCAGCTTCCGCTCGCTCAGCCCAGCGCCATCCGCAAGCAACGTGGAGGCCAGCTCGCAGCTGAAGCACATGTTGCTGGCGGAGCAGcccagcaagcagcagctgcagcagcagcagccggcgcaGCCTCCCTTGAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGAGAAGCCGCAGGCACCTGCCATGGACCTCAGCATGGATGTGCTGGACCTGAGCAAGAAGCCACAACGCGAACACGACGtgctcctgcagcagcagcagcagcagcagcagcaacagcagcaacaacagcagcagcaacagttgctcttCAATCCGGGCGATGCGGCCACGCAGtacatgcagctgctgcgcaatCTGATGCTGCAGCAGTCGTCCGGCTTTCCGTTCTTCGGGCTGATGGCGCCGCCGCCCAcagctgcggccgctgctgcgctgGAGAAGTCCGCGCCAGCCCTGGCCGTGccggcgacagcggcagcagttgctgccgggCCGCCGCCCCTGGGCCTGCGGCTGGGCGGGCTGGGCGTGCCGGTGCCCGCGGCCGGACCCGTCAAGATGGTCATCAAGAACGGCGTGCTGATGCccaagcagaagcagcgccGCTACCGCACCGAGCGGCCCTTCGCCTGCGAGCACTGCTCGGCCAGGTTCACGCTGCGCTCCAACATGGAGCGGCACgtgaagcagcagcatcccCAGTTCTacgcgcagcggcagcgcagcgGGCACCACGTGATGCGCGGGCGGGCGGCCAACTCGGGCGCAGCCCAAGCCgcagcggccgcagccgccgccgccgccgcagccgcagccatgACCAAtctgcaccagcagcagcagcagcagcagcatgcgcCCATCTCGGAGCAGGTGAAGTACGCGATCctggcgcagcagctgaaggcgCGCAAGGACACAGacctgctgcagcaggcgctggcGCACGGCTCCAGCAGCGTCGTCGTCAATCCCCTGCTGCACTTCAactacggcagcagcagcagcagcagcaacaacaacggcagcaaccagccgcagcagcagcagcagcagcagcagcagctgcccgtgGATGACGACGAACCGCCCAAGCTGATCATagacgaggacgaggaggacGAGTTCGAGGACAtagacgaggaggaggaggaggaggatgacGAAGAGCTGGAGGCAGacgagcagcaggaggagcagccgcagcagcaactggagcaAGTGCAGCCAATCGAAGTCGATGCCAAAGCTGAGCCCGAGCCGCAGCCAGCTGAGCCGGCGCCAGTGAAGCCCAGTGGCGAGCCGACCACCATGAAGACCATGATTGCCCAGGCCGAGTCGGTGGGCAAGTCCCTGAAGGAGGTGGCCAGCTCGCCGTTCAAGGACGAATCTCAGGACCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCCACCAGCAACCAGGTCTCGTTCAACAGCTACTTCCGGCCGAGCGACGTGGCCAACCACATGGAGCAGAGCGACGAGGAGGGCCTCGTCGCCTCCGGCAGCGCCAGCGAGAGCAACAACTCCGGCACGGAGGAcgtcaccagcagcagcagctgcagcgagccCAAGAAGAAGTCCGCCTACAGCCTGGCGCCCAACCGCGTCAGCTGCCCGTACTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATCCTCACCCACACGGGCCAGAAGCCCTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGACCGCCACCTGCTGCGCAAGCACGGCAACGTCGAGTCCGCCATGTCGGTCTACGTGCCCACCGAGGACGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTCGAGGAGAtcgagctggaggagcagcgGCGCCGCAAGGCGGCCGAAAAggagcgccagctgcagctcgagcgggagcgggagcgcgAACGCGAGCTGGAGCGGGAGCGCGAGCTGGAGCGCGagcgcaagcagcagcagctcatccaGCAGCTGACGGCAGCGGCCCAGCTCAGCCAGCAGATGGTGGCCGCCGCCcaagccgcagccgccgccgcagccaccagcagcggcagcggcggcgccgAGGCCAACGGCAGCGAGCTGCCCTACAAGTGTCACCTGTGCGAGTACTCGTTCGGCGAGCGGATGCAGTGCCTCGACCACatcaagcagcagcacgcCCAGGAGTTCGCGCTGCTCCTGGCCAAGGGCGCCATCGAGACGGAGCAGGAGAcggcagctgtggcagctgccgcctCGGCTGCAGCCAGCTCGGCGGCCGTCTCGGAGGACGAGTCCAGCACCGGACGCAACTCCGGCAAGTATCCGGACTACAGCAACCGCAAGGTGATCTGCGCCTTCTGCGTGCGCCGCTTCTGGTCCACGGAGGACCTGCGCCGGCACATGCGCACCCACTCGGGCGAGCGGCCGTTCCAGTGCGAGATCTGCCTGCGCAAGTTCACGCTGAAGCACAGCATGCTCCGGCACATGAAGAAGCACAGCGGGCGCAGCCACAACGGCGAGCCGGGCGCCTCCGACTGCTCCGACGACGAGCAGATGGCCACTCCGCCGACGACACCAACGCCCAcggccatgcccatgcccatgccgatgccgatgcccagcaacaacaacaacaacaacacttgccacaacaacaacaacagcaacaccaacaacaacaacaagagcttgCGCCTGCCCAAGCTGCACGAGCTGCTGGACAAGGCGAACGAGTGGCGCGTGAGTCGCCTCGGCGAGCACAAGGAGAACATCGCCGAGTCCTCGACGCCCACAACAGCGGCcgccgtgggcgtggccagcggcGACTTCCTGGGCAATCTGCTGGGCATCACCGACCAGGGCATACTCAACAAGCTGCTCAGCTCGCCGGACGAGGCGGCCAAGCTGCTGGGCGTGGAGAAGTGA
Protein Sequence: MLATQQQQQQPPQQQHTAATAAAGVALEDAVMERQRRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHVEATSRKRKMRQQQQPQQPILYSDEEDEQQQQQQQQQQQQLLEQSAHRMRHKQRRSGNAVAVAASASIVVDYSVGSDASSLRKKFRLNRSSISAHNGDLSESGFVDGSAHSGYLLSASSATQSATAAQQQQQQQQPGSGSSSGGSSPQGLCHSSAESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQQQQQQQQQQQQQQPQQQQAQTQQQQQPLQQQQQLQRHQQHAAGNAVAQRAESYESDASCSTDISSSSSSAASNNNNNNTSQANNNNSSQEEQQLLLACKQQQQLKTNINNNNIIVSDERALDTDGDGEAEADGAGDEAESVDVTQMITSTPDVATLLATSSGSSSPRTPEPEAAEGLLPSCPACNADGFETLAALYAHLEAEHADIPAKCRECEVIFATQRQLQAHSCRGLQLPPLLGASSSPLHKQEPAEEEDEEQQLRQHEAEAEADEDEDELRLQANSERDEFFQQLYLKGKSGGSSLPSPIKHEPSEQRQDLADIQSILQMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGREGEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDEVKRAIVYHPAEDASCEDIKPKMDPDLSELSFRSLSPAPSASNVEASSQLKHMLLAEQPSKQQLQQQQPAQPPLKIQVKSLDQLVEKPQAPAMDLSMDVLDLSKKPQREHDVLLQQQQQQQQQQQQQQQQQQLLFNPGDAATQYMQLLRNLMLQQSSGFPFFGLMAPPPTAAAAAALEKSAPALAVPATAAAVAAGPPPLGLRLGGLGVPVPAAGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRAANSGAAQAAAAAAAAAAAAAAMTNLHQQQQQQQHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVVNPLLHFNYGSSSSSSNNNGSNQPQQQQQQQQQLPVDDDEPPKLIIDEDEEDEFEDIDEEEEEEDDEELEADEQQEEQPQQQLEQVQPIEVDAKAEPEPQPAEPAPVKPSGEPTTMKTMIAQAESVGKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSCSEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRKAAEKERQLQLERERERERELERERELERERKQQQLIQQLTAAAQLSQQMVAAAQAAAAAAATSSGSGGAEANGSELPYKCHLCEYSFGERMQCLDHIKQQHAQEFALLLAKGAIETEQETAAVAAAASAAASSAAVSEDESSTGRNSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGEPGASDCSDDEQMATPPTTPTPTAMPMPMPMPMPSNNNNNNTCHNNNNSNTNNNNKSLRLPKLHELLDKANEWRVSRLGEHKENIAESSTPTTAAAVGVASGDFLGNLLGITDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00512904;
90% Identity: iTF_00559679;
80% Identity: -