Basic Information

Insect: Drosophila paucipuncta
Gene Symbol: zfh1
Assembly: GCA_035043875.1
Location: JAWNMP010000312.1:1348459-1355565[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.9e-05 0.0019 18.5 1.0 1 23 152 174 152 174 0.97

2 15 0.00088 0.058 13.9 1.2 3 23 182 202 180 202 0.94

3 15 9.6e-05 0.0063 16.9 0.1 1 23 372 394 372 394 0.98

4 15 0.00033 0.022 15.2 0.9 1 23 400 422 400 422 0.98

5 15 0.00012 0.0077 16.6 2.3 1 23 454 477 454 477 0.94

6 15 0.76 49 4.6 4.3 1 23 521 543 521 543 0.87

7 15 0.0042 0.28 11.7 0.4 1 23 549 572 549 572 0.98

8 15 0.028 1.8 9.1 0.4 3 19 581 597 580 598 0.95

9 15 0.00017 0.011 16.1 5.6 1 23 607 629 607 629 0.97

10 15 0.029 1.9 9.1 1.1 2 23 635 656 634 656 0.96

11 15 9.8e-06 0.00064 20.0 1.0 1 23 665 687 665 687 0.98

12 15 0.0011 0.072 13.5 0.1 3 23 695 715 693 715 0.97

13 15 5.9e-05 0.0039 17.5 0.5 1 23 721 743 721 744 0.95

14 15 0.05 3.3 8.3 0.4 1 23 754 776 754 776 0.97

15 15 0.00053 0.035 14.5 0.8 1 23 1282 1304 1282 1304 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.9e-05	0.0019	18.5	1.0	1	23	152	174	152	174	0.97
2	15	0.00088	0.058	13.9	1.2	3	23	182	202	180	202	0.94
3	15	9.6e-05	0.0063	16.9	0.1	1	23	372	394	372	394	0.98
4	15	0.00033	0.022	15.2	0.9	1	23	400	422	400	422	0.98
5	15	0.00012	0.0077	16.6	2.3	1	23	454	477	454	477	0.94
6	15	0.76	49	4.6	4.3	1	23	521	543	521	543	0.87
7	15	0.0042	0.28	11.7	0.4	1	23	549	572	549	572	0.98
8	15	0.028	1.8	9.1	0.4	3	19	581	597	580	598	0.95
9	15	0.00017	0.011	16.1	5.6	1	23	607	629	607	629	0.97
10	15	0.029	1.9	9.1	1.1	2	23	635	656	634	656	0.96
11	15	9.8e-06	0.00064	20.0	1.0	1	23	665	687	665	687	0.98
12	15	0.0011	0.072	13.5	0.1	3	23	695	715	693	715	0.97
13	15	5.9e-05	0.0039	17.5	0.5	1	23	721	743	721	744	0.95
14	15	0.05	3.3	8.3	0.4	1	23	754	776	754	776	0.97
15	15	0.00053	0.035	14.5	0.8	1	23	1282	1304	1282	1304	0.98

Sequence Information

Coding Sequence: ATGAACAATCCGAACTATGGCGGCATCCAGTGGATACAGCAGGAAAGCAGCGCCGTCGTCGACGATAGCGAATCAGAGATGACAGCAGCATATTTGGTCAACGCTGACGCCAATGGAAGCATTTCCAACGATGACGATCTCGATCATATGGCAGCCGAGAATCTCATCTTTATGGCACGCGACGGACAACTCAGCGAAATCATCGCCGCCAATGAGGCaaatggcggcagcagcacagTGCTAATCACGGAAAGCGATGGAAATACCGGTGTCGAGTACGCCGAGTCCTTTGAAGATGATGCCCAAGTCGTCACCGAGGAGATCATCACGGATGATTGGGTCCAGCATCAGGGTGCAGAGCGagTGGAAATTGCCGCTGAGCAAATCGCTGGCAACGGCAGCTCCCAGGAGCTGTTGGACATGCAACAGAATGAGTATATGGCGATGCGTCCCTATCCCTGTGACTTTTGCAGTCGACGGTTTCGGAAGAAGGCCAGCCTCAACAATCATATGCTGGCGCATCAGAATGATCGTCCCCATCTCTGCAAGCTGTGCGGCGCGCGTTTCTCGCGTCGCGCAGAGCTCATCAGCCACTTCAAGGCGCATGCGGATGCCCAGGTGGCCGCCGATGAAGAGGCAGCTGCGGCAGCCATAAAATTtgaaccacaacagcagctacagcaacagaaGCGACAAATTGAGGATCATTTCTGTGAGCAGGAATGGCCGCTGTAtcaggaacaggaacaggagcagGTCGAGGAGCAGCTGGAACAggtcgaggaggaggagccgcagcagcagcagcagcagttggaacagcatcagcagctgttgcaacaATTGGTGGCGCCACCAACCGCTGCCCGGGGACGCATCAGTCGCTTAAAGCTCAAGGAGGAGAGTTCGCAATATATTGTGATTGCCTCCGATAAACCTGAAGCGGAGACGGGGACGGAGTCGCCTCAATACATGCATTGCGAGGCGAATTGCGATCAATCACttgccaccaacaacaaccaactcCAATCAACGTCCAACAATGATGTTGATGGAGCAGAGGAGCAGGGGCACGCAACGCTGCGTTTTCCCGTGCTCGACGAGAGCAAACCCTTCGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCTCTCGTCTCGCACATCAAGAATCATCGCGTGGATTCGCCGTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAACTACAGTCTACAGGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAACTCGGAATATGATCCGGCATCGGCGGGCGATGAGGATACGGCAAGCGAATCCGAAGCGGAACAGCTTTACGGTAATTTCTACTGCGGCGAATGCGGCATCTCCTTTCACCGGCAGGATTTGTTGCGGCgccacagcaaacagcagcacaTCAAGCAGCTgcctgcaacaacagctggtaacaacaacaacaacaacaacagtgtggcaactgcaacaacaacggatGCAGATGCAGCTCCAACTGATgccgatgctgatgatgcCAAAGATGCGCCACATTGTTGCCACACGTGCGGCAAATCATTTCTCAGCGTACTCAAACTGCTCGCCCATACCGAAATCCACAAACGCTTCCCGCCATTCAAATGTGTCCTGTGCGGTGTCAGTTTCTACGAGGAGCAGGCCATAAAGCGGCACCTGAATACGCGGCATCCGCATGAGCTGAAGCCCAAttcgtgtgtgttgtgtggcaAGGAGTGTCGAGATCGGAAGGCGCTGATCAAACATGCATGGGATCATTCACGGGAGAAGTGCCACTCGTGCTCAAAGTGTGGCAAGAATTTCCACAACAAGGCGCGCCTGAAACGACACATGGCATCGCATCGCGACAAGTCCGTCGTGTGCGAAGTGTGCCACGAGGAGTTCCCAGATGGACGCAGCTTGTCCAATCATCGGCATTCCCATAGCACAACGTCGCCGGGCAAACTGTTTCCCTGCCACGAGTGTGGCAAGACTTTTGGGTCGCGCAGCTCGCAACAGATTCATGTGCGCATCCATACGGGTGAAAGGCCCTACGGTTGTCGCTACTGCTGGAAGGCCTTCGCTGATGGCGGCACTCTCCGCAAACACGAACGCATCCACACGGGCGAGAAGCCCTATGCCTGCTCCGTCTGTCCGCGTGCCTTCAATCAGCGTGTCGTGTTGCGGGAACACATCCGGTCGCATCATTCCGGTCTGGATGCGGCACGTGGCACGTATCATTGCACGGTCTGCTCCGCGGATTTGAGCTCATCGAATGACCTCATCCAGCATCTCATCCAGCACAGTGATACGAACACAGCCAAACAGCGACAGCCAATTACTGGTCCACGTAAATATAAACGTCGCCGGAAACTGCAGCCGCATGAGATTGCGCACATGCGCGCAGAGCACAAGGCTGGCGGGGGCGAAGGCGAGGAGGAGGATTATGGCAGCGACTTGGACTACTGCGATCTGGATGTGGAGAATGTGGATGAACTGCTGCAGGAGGCAGCCGCagagccaccaccaccagccaCCAAAAAAGCGAAACGCAAACGCAAAGCGCCAAATAAAACCGGCGATGAGCAAAGATTGTGGGATGAGAAATTCCTGCAGCAGGCGAGCAATGGGAACAGCGATGAGGCCTACAAGAGTTTCTTTCAAATGGACTCGCTGGTCGTGGTCAATGATCAAACGTTGCAGCCCGTTGATGCTGGTGTTGCCACGACCAAGTTGCAGCAGGCAGAGATTAAGGAGCAAAAACTCAAAACAGTCAatcgcagcagcaaaagaaggGCAGGCAAATCTGGGGGAGGAGTTGCAGGAGGAACAGCAGGAGTAGTagaagctgttgctgctccacGTCCCCGCATGATACACACGGCCAAGTCGCAGCAGACAACGTCAAGGAAATCCCGCACAAGGAGTTATGCCACACGCACCAGCACcaatgaacagcagcagcagcagcatcagcagccagGAGGAGGAGCAAGCCTCATCAAATCGCGCATTGTGGATGACTACGAGATCATCTCACCGGCCACACAGCCACCCAATCAGATCAGCTCCAGTCCGCTGCACATCAAACAGGAGCAGGAAcatcaacagcatcatcagcaacagcagcagcagcaacagcagagagTCCAACTGCTCTTCGATGACAGCCATCTGCTCATCGATGCGGGCCTGTTGCGTGAGAAGACCTACGAGAAATATAATCCGAGCATTGTCCAAGATCTCGAGGAGATATTGCGTAGTCCCCCCAAGCATGAGCGAAACGATCGACGGCTGCGCTTCATCAGCGAATCGTCGACGACGCCACAATTTCTGCCCGGCGAGGAGGAGGAACAGCATCTCATCAAGATCGAGCCAACGTCACCGGATCTACGCGAAATGGTTGAGAGCCAGCAACCAGCCACACTGTCTACATCCTCTTCCGCCGTCTGCTCAACGGCGGCACGAACTTCCCGCCACCTGCGACAGCTGACTGCCAATGGTTCCAGTTCCATTTCTACTGCCACTTCCAGTTCGAGTGCCGCTGCCAGCACGCGAGCCGCTGCCAAGCGCAATGCCAGCAAGCAGCTTGCAAAGAAATCCACTTCCAATAGCAGCAAAGCCAACTCATCATCGTCTTATCTCAGCTATGGCGTCGACTCCTAtaatgtgggcgtggcagccaGTGCCAATGGCTCCTCGGATGTCAGTTCCGGGTTCTTTTCCATTTCCGAGGTCGTCTCGGCAGcggatgctgctgatgcagctgcgaaggcggcggcggcagcagccagcaaaacGGAGCGAAGAACGCGCTGCTTTGAATGCGAAATGTGCTCGTCCAATTTTCCAGATCGCTCACAGCTGCTGGagcacatgcacatacacatctAG
Protein Sequence: MNNPNYGGIQWIQQESSAVVDDSESEMTAAYLVNADANGSISNDDDLDHMAAENLIFMARDGQLSEIIAANEANGGSSTVLITESDGNTGVEYAESFEDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHADAQVAADEEAAAAAIKFEPQQQLQQQKRQIEDHFCEQEWPLYQEQEQEQVEEQLEQVEEEEPQQQQQQLEQHQQLLQQLVAPPTAARGRISRLKLKEESSQYIVIASDKPEAETGTESPQYMHCEANCDQSLATNNNQLQSTSNNDVDGAEEQGHATLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGDEDTASESEAEQLYGNFYCGECGISFHRQDLLRRHSKQQHIKQLPATTAGNNNNNNNSVATATTTDADAAPTDADADDAKDAPHCCHTCGKSFLSVLKLLAHTEIHKRFPPFKCVLCGVSFYEEQAIKRHLNTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRSLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAARGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKAGGGEGEEEDYGSDLDYCDLDVENVDELLQEAAAEPPPPATKKAKRKRKAPNKTGDEQRLWDEKFLQQASNGNSDEAYKSFFQMDSLVVVNDQTLQPVDAGVATTKLQQAEIKEQKLKTVNRSSKRRAGKSGGGVAGGTAGVVEAVAAPRPRMIHTAKSQQTTSRKSRTRSYATRTSTNEQQQQQHQQPGGGASLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHHQQQQQQQQQRVQLLFDDSHLLIDAGLLREKTYEKYNPSIVQDLEEILRSPPKHERNDRRLRFISESSTTPQFLPGEEEEQHLIKIEPTSPDLREMVESQQPATLSTSSSAVCSTAARTSRHLRQLTANGSSSISTATSSSSAAASTRAAAKRNASKQLAKKSTSNSSKANSSSSYLSYGVDSYNVGVAASANGSSDVSSGFFSISEVVSAADAADAAAKAAAAAASKTERRTRCFECEMCSSNFPDRSQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00542584;
90% Identity: iTF_00499722;
80% Identity: -