Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 5.5e-05 0.27 11.5 0.0 12 48 64 100 59 103 0.92

2 7 0.0038 19 5.6 0.3 20 45 103 128 97 136 0.82

3 7 0.05 2.5e+02 2.0 0.5 18 44 129 155 125 158 0.81

4 7 0.0039 19 5.6 0.4 16 45 155 184 142 188 0.85

5 7 0.0028 14 6.1 0.7 18 44 185 211 181 215 0.90

6 7 0.0013 6.5 7.1 0.1 21 44 216 239 212 244 0.89

7 7 0.0079 40 4.6 0.2 21 44 244 267 241 274 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	5.5e-05	0.27	11.5	0.0	12	48	64	100	59	103	0.92
2	7	0.0038	19	5.6	0.3	20	45	103	128	97	136	0.82
3	7	0.05	2.5e+02	2.0	0.5	18	44	129	155	125	158	0.81
4	7	0.0039	19	5.6	0.4	16	45	155	184	142	188	0.85
5	7	0.0028	14	6.1	0.7	18	44	185	211	181	215	0.90
6	7	0.0013	6.5	7.1	0.1	21	44	216	239	212	244	0.89
7	7	0.0079	40	4.6	0.2	21	44	244	267	241	274	0.84

Coding Sequence: ATGGAACAAGTGATAGATGTGGGCTGTGTGAAGGAGGAGCACTGTGAGGCAATCTGCAATATGTTTAGAGCGCAGGATTGGCAGCTGACGATGAGGCACAGGGACTTGGGACTTGTCAAGATCGAACAGGATATGAGTATTGTGTGGCAAGGCAGTAGCACAGGCACAACAGACAACAAGGAACGAAACACAGAGAAGCAAAAAATTGCTGCTCTTGTGGAGAAACCATTCAAATGCCCGCATTGCAGCAAGGATTTCGCCACCAGCAGCAATCTCAAGGTGCATCTCTCTCGTACTCACTCCGGAGACCAAGAAAGACCATTTTTATGCCCCACTTGCCCCAAATCCTTTGCCACCAACGACAATCTGCAAAAACACATACGCAGGCATTCAAACGAAAGAACTCTAAACTGTCCGCATTGCCCAAAGGCTTTCGCCACCAAGGACAATCTGCAGAAACACATACGCAGGCATTCAAGCGAAAGGACCTTGATTTGTCCACACTGCCCCAAAGCCTTTGCTACCAATGACAACCTACAGAAGCACATACGCCGACATTCGAGTGAACGGACCCTACAATGTCCCCACTGCCCCAAGGCCTTTGCAACCAATGATAATCTGCAGCGGCACATACGTGGACACACAGGTGAACGGCCGTTCAAATGTCCGTACTGCCCAAAACCATTTGCTCAAAATCGGGATCTCAAGGCACACATACTGGAGCACACTGGGGAGAAGCCCTTCAAGTGTCCACACTGTCCAAAAGCCTGTGTACGAAGCGAAGGACTCAAAAAACACATACTCCGGCTCCACAAAGACATAGAACCAGAACCAGCACAAGCACAAGCCTCTAGCAATACTTTGGCCAAACAATGGCAAACGGCTGAGAAGACGTACGTTAACGATTCCAGTGGCAGAATCTTCATGTACAAATATGATCTGACTAAGAACACACGTATGCCCACAGGCGAGGCGTAA
Protein Sequence: MEQVIDVGCVKEEHCEAICNMFRAQDWQLTMRHRDLGLVKIEQDMSIVWQGSSTGTTDNKERNTEKQKIAALVEKPFKCPHCSKDFATSSNLKVHLSRTHSGDQERPFLCPTCPKSFATNDNLQKHIRRHSNERTLNCPHCPKAFATKDNLQKHIRRHSSERTLICPHCPKAFATNDNLQKHIRRHSSERTLQCPHCPKAFATNDNLQRHIRGHTGERPFKCPYCPKPFAQNRDLKAHILEHTGEKPFKCPHCPKACVRSEGLKKHILRLHKDIEPEPAQAQASSNTLAKQWQTAEKTYVNDSSGRIFMYKYDLTKNTRMPTGEA

Sequence clustering based on sequence similarity using MMseqs2