Basic Information

Insect: Drosophila paramelanica
Gene Symbol: -
Assembly: GCA_035043915.1
Location: JAWNMO010000674.1:5475874-5480982[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 8.6 5.3e+02 1.3 0.1 1 9 71 79 71 86 0.89

2 15 0.0011 0.065 13.6 0.5 1 23 143 165 143 165 0.98

3 15 0.00014 0.0088 16.4 1.3 1 23 394 416 394 416 0.98

4 15 1.9 1.2e+02 3.4 0.7 1 23 422 445 422 445 0.92

5 15 0.51 32 5.2 0.2 1 23 468 491 468 491 0.94

6 15 0.0013 0.078 13.4 1.9 3 23 762 782 761 782 0.92

7 15 0.05 3.1 8.3 1.4 1 23 788 811 788 811 0.98

8 15 1.4 86 3.8 1.8 2 23 848 869 847 870 0.87

9 15 0.0032 0.2 12.1 0.7 1 23 891 914 891 914 0.97

10 15 0.021 1.3 9.6 0.4 1 23 1156 1179 1156 1179 0.90

11 15 0.00076 0.047 14.1 4.8 1 23 1192 1214 1192 1214 0.98

12 15 0.00015 0.0093 16.3 0.2 2 23 1220 1242 1219 1242 0.95

13 15 0.00065 0.04 14.3 2.7 2 23 1249 1273 1248 1273 0.89

14 15 0.66 41 4.8 0.7 1 23 1278 1300 1278 1300 0.93

15 15 0.11 6.5 7.3 1.5 1 23 1306 1329 1306 1329 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	8.6	5.3e+02	1.3	0.1	1	9	71	79	71	86	0.89
2	15	0.0011	0.065	13.6	0.5	1	23	143	165	143	165	0.98
3	15	0.00014	0.0088	16.4	1.3	1	23	394	416	394	416	0.98
4	15	1.9	1.2e+02	3.4	0.7	1	23	422	445	422	445	0.92
5	15	0.51	32	5.2	0.2	1	23	468	491	468	491	0.94
6	15	0.0013	0.078	13.4	1.9	3	23	762	782	761	782	0.92
7	15	0.05	3.1	8.3	1.4	1	23	788	811	788	811	0.98
8	15	1.4	86	3.8	1.8	2	23	848	869	847	870	0.87
9	15	0.0032	0.2	12.1	0.7	1	23	891	914	891	914	0.97
10	15	0.021	1.3	9.6	0.4	1	23	1156	1179	1156	1179	0.90
11	15	0.00076	0.047	14.1	4.8	1	23	1192	1214	1192	1214	0.98
12	15	0.00015	0.0093	16.3	0.2	2	23	1220	1242	1219	1242	0.95
13	15	0.00065	0.04	14.3	2.7	2	23	1249	1273	1248	1273	0.89
14	15	0.66	41	4.8	0.7	1	23	1278	1300	1278	1300	0.93
15	15	0.11	6.5	7.3	1.5	1	23	1306	1329	1306	1329	0.95

Sequence Information

Coding Sequence: ATGGCGCACAAGCGTGTAAAAATAGAGAACATGGCAgtgaattataaatttgcgTGTCGCTGTTGCCTCAAATCCGAGGCAGAGTTCTTCAAGCTGGATTCGCTAATCGACTGCGGGATTGGCGACAACGATGCGACTGCAACAAAAATACCCCTAATACGTTTATTATTGTTCTGCATGCGCACGGAAAATCTGCCCGAGCTGCCGCAATACATTTGCACTGAGTGCAGCAAAAGTTTGCAAATAGCCTATTTGTTCATACAGAACGGCTTGCGCGCCCACGAAATACTCTGCCGCAAATTGTGCCCCGGTCAGTTGAAGTCCACAACGCGCTCGAACGGCCAACACATGTCTCTGACGCAAGAGTCAGAGGACGCGAGGCTGGGCAGGCACGGGGAGCTGAAGTCAACAAAAGCCGCTGTGCGACACGAATGCAAAGTATGCGGTGCTATTATCTACAATCGCATGGAGCTAAAGCAGCACATACGCATGCATACAGAGGCGTCGCGACATCAgtgcaaattgtgcaaatttgtCACGCTCAAGCATCGCCAGCTGCCGGAGCATTATCGCAAGGCGCACGGCCTTACAGCTGCCCAAATTGAGCATCAGCTGAAAATACGTAAATCCATGCAGGCGGCAgcaaatgcaataacaacatcaacagcagctgcgacagcaacagcaatagctgCGGACGATGGTCAAGTGAAGGTGTGCACACTGGAGGATATGGAGCTGCTGATACCCACTGTGCTGACGCCGGAGGACTTTTCGCATCCACAATTGGACGCGGAACAGTTGCGTGATATTGAACAACAATTGGCAAACTCGCTGCCCGTCCCACAGTCCAGTTCAACGTACGATATGGAACCAACGATAGCTGCTGGCGGTGGCCCCAATGTGAGCATAGGCACCGAATTTCTGGTGCTGCCGGATGGATCGTTGCAGCAGGTGAACGATGGCGGTGTCGTATTCGAATATATTGACGATAGCAAGAACGTCGCCAATGCGGCAACCAATATGACGTTGCAGAGCCTGTTGGGTGATTCTAAGCCAGATTTAACATATGACCCCATGGATATCGATCTGAGTCATATGGTTCTCGACAATGCGCTGCCGCAAATAACagTTAAGCCAAAGCCACGGCCGGCACCAGCGTCAACGGGCGCCTTGAAGCACAAATGCAAACTGTGCCCCAAAGCATTTCCCACAGTGGCACGACTGAAATCTCATCAATTGACCCATAGTCATTTGCCCAAGTTCTATTGCGATCAGTGTGCTTACTACTCGCTGCGCAGCTCCGATCTCATCCAGCATTATACCACGGAGCACAAATCCTGCGTTGCTGAAAGTCGAGTTAACCATTATGAAAAGCTGCCCGGGGACAAAAGTCGCATATATTCCTGCGATATGTGCTTGTTTGAGGCGCCGAGCAGTGGTCAGCTGCGTGCACATTATAGCAATAAGCATATGGTTGTGCCCAGTGAGGTGCAGCTGCGTCCGACCTGGACGCACGAGTCAAGAGAGAGGGACGCCAACTCGACGCTAACTGACGGTAACGGCTCCGCACAGCCAGATATACCGTTGGGCATCAAATATCCGCCAATGATGTCTTCGGAAACAACAACCGAGCCAACATCGGTGTCAACAACTGTAATTGGGCAGCCGGCACAGGCCACAACGACAACTGTGGTAACGCCAGATGGGGATATCAATGTTGTGGTTGATGCCACATCGTTATTCTATGCAGCGGGTGCACCGGACCAGTTAACAACAACTGAAGGGACGACAaagacaacaagaacaacggcatcatcaacaaattcaaatacatttGGATTGTTCCCAGAGCAATCGTTTGGCAACAGTATTgcgagcacaacaacaatgtcacAGGAACCCAATGCTGTGCAGTCTACGACGTCCACATCGAATCCAAATACTAGCATCTTGGGTGACATGCAAGATTTTATTGATAACACCGATGTGGCTGCCATATGCACCATACCCGCCGATGATATGCCCGTGGTCGATGGCGATGACATTGTTATagataacaataatataagtCTGGACTTTGATGCGGAAAATCTATTTGAAGACTTTGAGGATGTTGAGGTGGGCGAAgaggatgatgacgatgaagatgatgatgcCGAAAATGAAGATGagaatgataataataatgcggCGGCCGATCAAAATCTATTGCTGACCAGCGACGATGACGATGTGGATGACTTTGATGATGAACAGTCGAAGCATTTGCAGAAACCATATTGCATCTATTGTAATAAGAAGTTCACCAGCCAATACAAGTTTGAGAACCACATGTTTGTACATCGCGGTTTGGCGCCTTATCGCTGTGAACTGTGCACCAATCTGTACAATATGAAACGTCTGCTAATAAGGCATTATAAGACGGTGCACAAGCGAATGCCCACACGGGACATGGTGCAGGCTAAGGGCGATAAGGTATCCGTGGCGAGTACAACCATTGAAAAAATACAAGTCAATAATGACAAACCTCCTATGCTAATGTGCGCCAAGTGTCCCTTCGAATGCGAGCTTGAGAGTGAAATGCGCAAGCATCTGAATGCGCATCATGGCATCAACGATGGCGTATCTGCGCATGCCAACGAGGTGTTTATCATACGCAAACTGCCCTATGAGTGTCCACGGTGCATACGTTCATTTGCAGCCAAACGCACGCTGACTCGCCATTTGCAACGTAGCCATTTGGTGGACACAATCATTGAGATGCAGGCGCCTCAATTGACAACTAGCTCAGCGGCCACCACGACCACATCGACGGCAACAACCACATTGCCGCTGAACGCCTGTGATggcaataaaacaacaacaacagcaacaacaataacaacacaacTGGATTCCAACATGTTGGCGCCGCAAGACGCTGAGACTGTCcacggcgatggcgatggcgatggagATGGCGATGGAAAATGCGAAGAGAACGCGCTAGACAAGGAAACAGGATACAAAACGCAAAATTCAGATACATTTATcataagcaaaacaacaacagcagcagctacaacaacagcacaagaAACAAacgaagcagcaacaacagctatcACATCATTAGCTGAAAATACAGAAGCTGATTCAGTAACAGCGACAGAAGCCGCAGAAGCTGCAACAACTaccacaacagcaataacaacagctgaGAATTTgtcaacaacatcagcaacaactacaacaacaaccgcaggCTCTACGCTCTTTCCAACGCCCACGCCATTTGACTTTGATCTTGACTTTATTGGCAACGGTGCACAAGCTGACATGCCCATTAAGAATAACAATGACAGCTTTAGCATTGCATCGAATTCCAGTCATCTCCTTAATGGCAGCGATAAGCTGCTGTCTGCAGCGTTGGAGCCATCGCCAGTTAAGGATTTACGCACACGGCTGCCGCGTACACCCATCTTTGTGTGCAAGCAATGCAATCAGACCTTCGATGAGCTCGGCAAGCTGTTGCAGCACGAACTGGATCAACATTCCAGCGGCATTGTGTCGCCGCGCAGCAGTTACCAGCATCAGTGCAAGATCTGTAAGACCACATACCGTACCATAACGCTACTCAACTATCATATGAAACGGCATGCGCCAGTCAAACTTCCGTGTAAACAGTGCTCCAAGGAGTTTGAGGAGAGTTCGGATTTGGAACAGCACATACAGTCCGAGCATAGCACCAATTTGCCGCTCCAATGCGGCGTGGATGGCTGCACGAAGACATTCGCCTATAAACATCATCTGAAACGTCATCAGACAGCCTCCCATACGCCAGTTCAGTATATTTGCCCGGAGTGCGGATGCGATATGCTAACCAGTCTGCAGCTAAGGAATCACTTGTCCACGCACAAGGGTACACATTCCTACAAGTGTCCGAAATGTGTGCGCACTTATCTGCGGCGCAAACCTTTTCGGAGACATGCGCTACGTGAGCACAAATGGGAGCTGACTGAGGaagaaattgataaaatatattgcgTAAATAGTCCATCGCCGTCAATTAAATTGCGTGAACGAAGATCGGTGAAGGCTGGGAATGACCGGTATGACTAG
Protein Sequence: MAHKRVKIENMAVNYKFACRCCLKSEAEFFKLDSLIDCGIGDNDATATKIPLIRLLLFCMRTENLPELPQYICTECSKSLQIAYLFIQNGLRAHEILCRKLCPGQLKSTTRSNGQHMSLTQESEDARLGRHGELKSTKAAVRHECKVCGAIIYNRMELKQHIRMHTEASRHQCKLCKFVTLKHRQLPEHYRKAHGLTAAQIEHQLKIRKSMQAAANAITTSTAAATATAIAADDGQVKVCTLEDMELLIPTVLTPEDFSHPQLDAEQLRDIEQQLANSLPVPQSSSTYDMEPTIAAGGGPNVSIGTEFLVLPDGSLQQVNDGGVVFEYIDDSKNVANAATNMTLQSLLGDSKPDLTYDPMDIDLSHMVLDNALPQITVKPKPRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCAYYSLRSSDLIQHYTTEHKSCVAESRVNHYEKLPGDKSRIYSCDMCLFEAPSSGQLRAHYSNKHMVVPSEVQLRPTWTHESRERDANSTLTDGNGSAQPDIPLGIKYPPMMSSETTTEPTSVSTTVIGQPAQATTTTVVTPDGDINVVVDATSLFYAAGAPDQLTTTEGTTKTTRTTASSTNSNTFGLFPEQSFGNSIASTTTMSQEPNAVQSTTSTSNPNTSILGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDDDDEDDDAENEDENDNNNAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVASTTIEKIQVNNDKPPMLMCAKCPFECELESEMRKHLNAHHGINDGVSAHANEVFIIRKLPYECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPLNACDGNKTTTTATTITTQLDSNMLAPQDAETVHGDGDGDGDGDGKCEENALDKETGYKTQNSDTFIISKTTTAAATTTAQETNEAATTAITSLAENTEADSVTATEAAEAATTTTTAITTAENLSTTSATTTTTTAGSTLFPTPTPFDFDLDFIGNGAQADMPIKNNNDSFSIASNSSHLLNGSDKLLSAALEPSPVKDLRTRLPRTPIFVCKQCNQTFDELGKLLQHELDQHSSGIVSPRSSYQHQCKICKTTYRTITLLNYHMKRHAPVKLPCKQCSKEFEESSDLEQHIQSEHSTNLPLQCGVDGCTKTFAYKHHLKRHQTASHTPVQYICPECGCDMLTSLQLRNHLSTHKGTHSYKCPKCVRTYLRRKPFRRHALREHKWELTEEEIDKIYCVNSPSPSIKLRERRSVKAGNDRYD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598403;
90% Identity: iTF_00541977; iTF_00561265;
80% Identity: -