Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: -
Assembly: GCA_004149445.1
Location: SCDR01001262.1:44319-49584[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00086 0.1 13.6 0.5 1 23 143 165 143 165 0.98

2 14 0.00012 0.014 16.4 1.3 1 23 395 417 395 417 0.98

3 14 4.8 5.8e+02 1.8 0.4 1 23 423 446 423 446 0.90

4 14 0.64 76 4.6 0.2 1 23 469 492 469 492 0.94

5 14 0.001 0.12 13.4 1.9 3 23 761 781 760 781 0.92

6 14 0.041 4.9 8.4 1.4 1 23 787 810 787 810 0.98

7 14 1.1 1.4e+02 3.8 1.8 2 23 847 868 846 869 0.87

8 14 0.0026 0.31 12.1 0.7 1 23 890 913 890 913 0.97

9 14 0.017 2 9.6 0.4 1 23 1140 1163 1140 1163 0.90

10 14 0.00061 0.074 14.1 4.8 1 23 1176 1198 1176 1198 0.98

11 14 0.00013 0.016 16.2 0.1 2 23 1204 1226 1203 1226 0.96

12 14 0.00053 0.063 14.3 2.7 2 23 1233 1257 1232 1257 0.89

13 14 0.53 64 4.8 0.7 1 23 1262 1284 1262 1284 0.93

14 14 0.085 10 7.4 1.5 1 23 1290 1313 1290 1313 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00086	0.1	13.6	0.5	1	23	143	165	143	165	0.98
2	14	0.00012	0.014	16.4	1.3	1	23	395	417	395	417	0.98
3	14	4.8	5.8e+02	1.8	0.4	1	23	423	446	423	446	0.90
4	14	0.64	76	4.6	0.2	1	23	469	492	469	492	0.94
5	14	0.001	0.12	13.4	1.9	3	23	761	781	760	781	0.92
6	14	0.041	4.9	8.4	1.4	1	23	787	810	787	810	0.98
7	14	1.1	1.4e+02	3.8	1.8	2	23	847	868	846	869	0.87
8	14	0.0026	0.31	12.1	0.7	1	23	890	913	890	913	0.97
9	14	0.017	2	9.6	0.4	1	23	1140	1163	1140	1163	0.90
10	14	0.00061	0.074	14.1	4.8	1	23	1176	1198	1176	1198	0.98
11	14	0.00013	0.016	16.2	0.1	2	23	1204	1226	1203	1226	0.96
12	14	0.00053	0.063	14.3	2.7	2	23	1233	1257	1232	1257	0.89
13	14	0.53	64	4.8	0.7	1	23	1262	1284	1262	1284	0.93
14	14	0.085	10	7.4	1.5	1	23	1290	1313	1290	1313	0.95

Sequence Information

Coding Sequence: ATGGCGCACAAGCGTGTGAAAATAGAGAACATGGcagtaaattataaatttgcgTGTCGCTGTTGCCTCAAATCCGAGGCAGAGTTCTTCAAGCTGGACTCGCTAATCGACTGCGGGATTGGCGACAGCGATGCGACCGCAACAAAAATACCCCTTATACGTTTACTATTGTTCTGCATGCGCACGGAAAATCTGCCCGAGCTGCCGCAATACATTTGCGCTGAATGCAGCAAAAGTTTGCAAATTGCCTATTTGTTCATACAGAACGGCTTGCGCGCCCACGAGATACTCTGCCGCAAATTGTGCCCCGGCCAGGTGAAGTCCACAACGCGCTCGAATGGCCAACACATGTCTCTGACGCAAGAGTCAGAGAATGCGACGCTGGGCCGGCACGGGGGGCTGAAGTCAACAAAAGCCGCTGTGCGACATGAATGCAAAGTATGCGGTGCTATTATCTACAATCGCATGGAGCTCAAGCAGCACATACGCATGCATTCAGAGGCGTCGCGACATCAGTgtaaattgtgcaattttgtCACGCTCAAACATCGCCAGCTGCCGGAGCATTATCGCAAGGCGCACGGCCTTACAGCTGCCCAAATTGAGCATCAGCTCAAAATACGCAGATCCATGCAGGCGGCAGcaaatgcaataacaacatcaacagcggctgcgaaagcagcaacaacaacagttgcggACGATGGTCAAGTGAAGGTGTGCACACTGGAGGATATGGAACTGCTGATACCCACTGTGCTGACGCCGGAGGATTTTTCGCATCCACAATTGGATGCGGAACAGTTGCGTGATATTGAACAACAATTGGCAAACTCGCTGCCCGTCCCACAGTCCAGTTCAACGTACGCTGCGGAACCAACGATACCTGCTGGCGGTGGCGCCAATGTGAGCATAGGCGCCGAATTTCTGGTCCTGCCCGATGGCTCGTTGCAGCAGGTTAACGATGGCGGTGTCGTATTCGAATATATTGACGATAGCAAGAACGTCGCCAATGCGGCAACCAATATGACGTTGCAGAGCTTGTTGGGTGATTCCAAGCCAGATTTAACATTTGACCCCATGGATATCGATCTGAGTCATATGGTTGTCGACAATGCGTTGCCGCAAATcacagTTAAGCCAAAGCCACGGCCGGCACCAGCGTCAACGGGCGCCTTGAAGCACAAATGCAAACTGTGCCCCAAAGCATTTCCCACAGTGGCACGTCTGAAATCTCATCAATTAACTCATAGTCATTTGCCCAAATTCTATTGCGATCAGTGCGCTTATTATTCGCTGCGCAGCGCCGATCTCATCCAGCATTATACCACGGAGCACAAGTCCTGCGTTACCGAAAGTCGAGCGAACCATTATGATAAGCTGTCCGGGGACAAAAGTCGCATATATTCCTGCGATATGTGCTTGTTTGAGGCGCCGAGCAGTGGTCAACTGCGTGTACATTATAGCAATAAGCATATGGTTGTGCCCACTGAGGTGCAGCTGCGTCCCACCTGGACGCACGAGTCAAGGGAGAGGGACGGCAGCTCGGTAACTGACGGAAATGGCTCCGCACAGCCAGATATACCGCTGGGCATCAAATATCCGCCAATGATGTCTTCAGGAACAACAACCGAGCCAACATCGGCGTCAACAAGTGCCATTGGGCAGCCAAGGcaggctacaacaacaactgtggtAACACCAGATGGAGAAATTAATGTTGTGGTTGACGCCACATCGTTATTCTATGCAGCGGGTGCAGCGGACCAGTTAACAACAACGAAAGGGAcgacaaagacaacaacaacggcatcAGCAACAAATTCAAACACATTTGGATTGTTCCCAGATCAGTCGTTTGGCAACAGTATGgcgagcacaacaacaatgtcgcAGGAGCCAAACAGTGTGCCGTCTGCGACATCTGCATCGAATCCAACTAATAGCATGTTTGGTGACATGCAGGATTTTATTGATAACACCGATGTGGCTGCCATATGCACTATACCCGCCGATGATATGCCAGTGGTCGATGGCGATGATATTGTTAttgataacaataatatagGTCTAGACTTTGATGCGGAAAATCTATTCGAAGACTTTGAGGATGTTGAGGTGGGCGAAgaggatgatgacgatgatgatgacgatgccGAAAATGAAGATGAGAATGATAACAATAATGCGGCGGCCGATCAAAATCTATTGCTGACcagcgacgatgacgacgtGGATGACTTTGATGACGAACAGTCGAAGCATCTGCAGAAACCATATTGCATCTATTGTAATAAGAAGTTCACCAGCCAATACAAGTTTGAGAATCACATGTTTGTACATCGCGGTTTGGCGCCTTATCGCTGTGAACTGTGCACCAACCTGTACAATATGAAACGTCTGCTCATACGGCATTATAAGACGGTGCACAAGCGAATGCCCACACGGGACATGGTGCAGGCGAAGGGCGATAAGGTATCCGTGGCGAGTACAACCATTGAAAAAATACAAGTTAATAATGACAAACCTTGTATGCTAATGTGCGCCAAGTGTCCCTTCGAATGCGAGCTTGAGAGTGAAATGCGCAAGCATCTGAATGCCCATCATGGCATCAACGATGGCGTATCTGTGCATGCCAACGAGGTGTTTATTATACGCAAACTTCCATATGAGTGTCCACGGTGTATACGCTCATTTGCGGCCAAACGCACGCTTACTCGCCATTTGCAACGTAGCCATTTGGTGGACACAATCATTGAGATGCAGGCGCCTCAATTGACAACTAGCTCAGCGGCCACCACGACCACATCGACGGCAACAACTACATTGCCGTTGAACGCCAGTGAtggcaataaaacaacaacaacggcaacaacaatacaactGGATTCCAACATGTTGGCGCCGCAAGACGCCGAGACTgtcgatggcgatggcgatggaaAATGTGAAGAGAACGCCCTAGACAAGGAAACAGGATTAAAAACGgaaaatttacatacatttatcaaaagcgaaagaacaacaacaacagcagcaacaacaacaacaacaacagctaccaCATCATTAGCTgaaaaagcagaagctgcaTCAGTAACAACGACAGAAGATGCAGAAGTTGcaaaaacaaccacaacaacaacaacagttgaaaatacatcaacaacatcagcaacaactacaacaacaaccgcaggCTCTACGCTCTTTCCAACGCCCACGCCATTTGACTTTGATCTTGACTTTATTGGCAACGGTGCACAAGTTGCCACGcctattaaaaacaacaatgacagcTTCAACATTGCGTCGAATTCCAGTCATCTGCTTAATGGCAGCGATAAGCTGCTGACTGCAGCGTTGGAGCCATCGCCAGTTAAGGATTTACGCACACGACTGCCGCGTACACCCATCTTTGTGTGCAAGCAATGCAATCAGACCTTCGATGAGCTCGGCAAGCTGTTGCAGCACGAACTGGATCAACATTCCAGCGGCATTGTGTCGCCGCGCAGCAGTTACCAGCATCAGTGCAAGATCTGTAAGACCACATACCGCACCATAACGCTACTCAACTATCATATGAAACGGCATGCGCCAATCAAAATTCCGTGTAAGCAGTGCTCCAAGGAGTTTGAGGAGAGTTCGGATTTAGAACAGCATATACAGTCCGAGCATAGCGCCAATATGCCCCTCCAATGCGGCGTGGATGGCTGCACGAAGACATTCGCCTATAAACATCATCTGAAGCGTCATCAGACAGCCTCCCATACGCCGGTTCAGTATATTTGCCCGGAGTGCGGATGCGATATGCTAACCAGTCTGCAGCTAAGGAATCACTTGTCCACGCACAAGGGTACACATTCCTACAAGTGTCCGAAATGCGTGCGCACTTATTTGCGGCGCAAACCTTTTCGGAGACATGCGCTACGTGAGCACAAGTGGGAGCTGACTGAGGaagaaattgataaaatatattgcgtAAATAGTACATCACCGTCAATCAAATTGCGTGGACGAAGATCGGTGAAGGTTGAGAGGGACCGGTATGACTAG
Protein Sequence: MAHKRVKIENMAVNYKFACRCCLKSEAEFFKLDSLIDCGIGDSDATATKIPLIRLLLFCMRTENLPELPQYICAECSKSLQIAYLFIQNGLRAHEILCRKLCPGQVKSTTRSNGQHMSLTQESENATLGRHGGLKSTKAAVRHECKVCGAIIYNRMELKQHIRMHSEASRHQCKLCNFVTLKHRQLPEHYRKAHGLTAAQIEHQLKIRRSMQAAANAITTSTAAAKAATTTVADDGQVKVCTLEDMELLIPTVLTPEDFSHPQLDAEQLRDIEQQLANSLPVPQSSSTYAAEPTIPAGGGANVSIGAEFLVLPDGSLQQVNDGGVVFEYIDDSKNVANAATNMTLQSLLGDSKPDLTFDPMDIDLSHMVVDNALPQITVKPKPRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCAYYSLRSADLIQHYTTEHKSCVTESRANHYDKLSGDKSRIYSCDMCLFEAPSSGQLRVHYSNKHMVVPTEVQLRPTWTHESRERDGSSVTDGNGSAQPDIPLGIKYPPMMSSGTTTEPTSASTSAIGQPRQATTTTVVTPDGEINVVVDATSLFYAAGAADQLTTTKGTTKTTTTASATNSNTFGLFPDQSFGNSMASTTTMSQEPNSVPSATSASNPTNSMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNIGLDFDAENLFEDFEDVEVGEEDDDDDDDDAENEDENDNNNAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVASTTIEKIQVNNDKPCMLMCAKCPFECELESEMRKHLNAHHGINDGVSVHANEVFIIRKLPYECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPLNASDGNKTTTTATTIQLDSNMLAPQDAETVDGDGDGKCEENALDKETGLKTENLHTFIKSERTTTTAATTTTTTATTSLAEKAEAASVTTTEDAEVAKTTTTTTTVENTSTTSATTTTTTAGSTLFPTPTPFDFDLDFIGNGAQVATPIKNNNDSFNIASNSSHLLNGSDKLLTAALEPSPVKDLRTRLPRTPIFVCKQCNQTFDELGKLLQHELDQHSSGIVSPRSSYQHQCKICKTTYRTITLLNYHMKRHAPIKIPCKQCSKEFEESSDLEQHIQSEHSANMPLQCGVDGCTKTFAYKHHLKRHQTASHTPVQYICPECGCDMLTSLQLRNHLSTHKGTHSYKCPKCVRTYLRRKPFRRHALREHKWELTEEEIDKIYCVNSTSPSIKLRGRRSVKVERDRYD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598403;
90% Identity: iTF_00567783;
80% Identity: -