Basic Information

Insect: Drosophila melanica
Gene Symbol: -
Assembly: GCA_004143765.1
Location: SCDT01000386.1:51899-57933[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 6.5 6.5e+02 1.3 0.1 1 9 71 79 71 86 0.89

2 15 0.00079 0.08 13.6 0.5 1 23 143 165 143 165 0.98

3 15 0.00011 0.011 16.4 1.3 1 23 394 416 394 416 0.98

4 15 1.4 1.4e+02 3.4 0.7 1 23 422 445 422 445 0.92

5 15 0.38 38 5.2 0.2 1 23 468 491 468 491 0.94

6 15 0.00094 0.094 13.4 1.9 3 23 762 782 761 782 0.92

7 15 0.038 3.8 8.3 1.4 1 23 788 811 788 811 0.98

8 15 1 1e+02 3.8 1.8 2 23 848 869 847 870 0.87

9 15 0.0024 0.24 12.1 0.7 1 23 891 914 891 914 0.97

10 15 0.015 1.5 9.6 0.4 1 23 1157 1180 1157 1180 0.90

11 15 0.00057 0.057 14.1 4.8 1 23 1193 1215 1193 1215 0.98

12 15 0.00011 0.011 16.3 0.2 2 23 1221 1243 1220 1243 0.95

13 15 0.00048 0.049 14.3 2.7 2 23 1250 1274 1249 1274 0.89

14 15 0.49 49 4.8 0.7 1 23 1279 1301 1279 1301 0.93

15 15 0.66 66 4.4 1.9 1 23 1307 1330 1307 1330 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	6.5	6.5e+02	1.3	0.1	1	9	71	79	71	86	0.89
2	15	0.00079	0.08	13.6	0.5	1	23	143	165	143	165	0.98
3	15	0.00011	0.011	16.4	1.3	1	23	394	416	394	416	0.98
4	15	1.4	1.4e+02	3.4	0.7	1	23	422	445	422	445	0.92
5	15	0.38	38	5.2	0.2	1	23	468	491	468	491	0.94
6	15	0.00094	0.094	13.4	1.9	3	23	762	782	761	782	0.92
7	15	0.038	3.8	8.3	1.4	1	23	788	811	788	811	0.98
8	15	1	1e+02	3.8	1.8	2	23	848	869	847	870	0.87
9	15	0.0024	0.24	12.1	0.7	1	23	891	914	891	914	0.97
10	15	0.015	1.5	9.6	0.4	1	23	1157	1180	1157	1180	0.90
11	15	0.00057	0.057	14.1	4.8	1	23	1193	1215	1193	1215	0.98
12	15	0.00011	0.011	16.3	0.2	2	23	1221	1243	1220	1243	0.95
13	15	0.00048	0.049	14.3	2.7	2	23	1250	1274	1249	1274	0.89
14	15	0.49	49	4.8	0.7	1	23	1279	1301	1279	1301	0.93
15	15	0.66	66	4.4	1.9	1	23	1307	1330	1307	1330	0.95

Sequence Information

Coding Sequence: ATGGCGCACAAACGTGTAAAAATAGAGAACATGGCAgtgaattataaatttgcgTGTCGCTGTTGCCTCAAATCCGAGGCAGAGTTCTTCAAGCTGGATTCGCTAATCGACTGCGGGATTGGCGACAACGATGCGACTGTAACAAAAATACCCCTAATACGTTTATTATTGTTCTGCATGCGCACGGAAAATCTGCCCGAGCTGCCGCAATACATTTGCACTGAGTGCAGCAAAAGTTTGCAAATAGCCTATTTGTTCATACAGAACGGCTTGCGCGCCCACGAAATACTCTGCCGCAAATTGTGCCCCGGCCAGTTGAAGTCCACAACGCGCTCGAACGGCCAACACATGTCTCTGACGCAAGAGTCAGAGGATGCGACGCTGGGCAGGCACGGGGAGCTGAAGTCAACAAAAGCCGCTGTGCGACACGAATGCAAAGTATGCGGTGCTATTATCTACAATCGCATGGAGCTTAAGCAGCACATACGCATGCATACAGAGGCGTCGCGACATCAGTGCAAACTGTGCAAATTTGTCACGCTCAAGCATCGCCAGCTGCCGGAGCATTATCGCAAGGCGCACGGCCTTACAGCTGCCCAAATTGAGCATCAGCTGAAAATACGTAAATCCATGCAGGCggcagcaaatgcaataacaacatcaacagcagctgcgacagcaacaacaacagctgcggaCGATGGTCAAGTGAAGGTGTGCACACTGGAGGATATGGAGCTGCTGATACCCACTGTGCTGACGCCGGAGGACTTTTCGCATCCACAATTGGACGCGGAACAGTTGCGTGATATTGAACAACAATTGGCCAACTCGCTGCCCATCCCACAGTCCAGTTCAACGTACGATATGGAACCAACGATAGCTGCTGGCGGTGGCCCCAATGTAAGCATAGGCACCGAATTTCTGGTGCTGCCGGATGGATCGTTGCAGCAGGTGAACGATGGCGGTGTCGTATTCGAATATATTGACGATAGCAAGAACGTCGCCAATACGGCAACCAATATGACGTTGCAGAGCCTGTTGGGTGATTCTAAGCCAGATTTAACATATGACCCCATGGATATCGATCTGAGTCATATGGTTATTGACAATGCGCTGCCGCAAATaacagTTAAGCCAAAGCCACGGCCGGCACCAGCGTCAACGGGCGCCTTGAAGCACAAATGCAAACTGTGCCCCAAAGCATTTCCCACAGTGGCACGACTGAAATCTCATCAATTGACCCATAGTCATTTGCCCAAGTTCTATTGCGATCAGTGCGCTTACTACTCGCTGCGCAGCTCCGATCTCATCCAACATTATACCACGGAGCACAAATCCTGCGTTACTGAAAGTCGAGTTAACCATTATGAAAAGCTGCCCGGGGAGAAAAGTCGCATTTATTCCTGCGATATGTGCTTGTTTGAGGCGCCGAGCAGTGGTCAGCTGCGTGCACATTATAGCAATAAGCATATGGTTGTGCCCAGTGAGGTGCAGCTGCGTCCGACATGGACGCACGAGTCAAGAGAGAGGGTCGCCAACTCGACGCTAACTGACGGTAACGGCTCCGCACAGCCAGATATACCGTTGGGCATCAAATATCCGCCAATGATGTCTTCGGAAACAACAACCGAGCCAACATCGGTGTCAACAACTGTAATTGGGCAGCCGGCACAGGCCACAACGACAACTGTGGTAACGCCAGATGGGGATATCAATGTTGTGGTTGATGCCACATCGTTATTCTATGCAGCGGGTGCACCGGACCAGTTAACAACAACTGAAGGGACGACAaagacaacaagaacaacggcatcagcaacaaattcaaatacatttgGATTGTTCCCAGAGCAATCGTTTGGCAACAGTATTgcgagcacaacaacaatgtcacAGGAACCCAACGCTGTGCCGTCTACGACGTCCACATCGAATCCAAATACTAGCATCTTGGGTGACATGCAAGATTTTATTGATAACACCGATGTGGCTGCCATATGCACCATACCCGCCGATGATATGCCCGTGGTCGATGGCGATGACATTGTTAtagataacaataatataagtCTGGACTTTGATGCGGAAAATCTATTTGAAGACTTTGAGGATGTTGAGGTGGGCGAAgaggatgatgacgatgaagatgatgatgcCGAAAATGAAGATGagaatgataataataatgcggCGGCCGATCAAAATCTATTGCTGACCAGCGACGATGACGATGTGGATGACTTTGATGACGAACAGTCGAAGCATCTGCAGAAACCATATTGCATCTATTGTAACAAGAAGTTCACCAGCCAATATAAGTTTGAGAACCACATGTTTGTACATCGCGgTTTGGCGCCTTATCGCTGTGAACTGTGCACCAATCTGTACAATATGAAACGTCTGCTAATAAGGCATTATAAGACGGTGCACAAGCGAATGCCCACACGGGACATGGTGCAGGCTAAGGGCGATAAGGTATCCGTGGCGAGTACCACCATTGAAAAAATACAAGTCAATAATGACAAACCTCCTATGCTAATGTGCGCCAAGTGTCCTTTCGAATGCGAGCTTGAGAGTGAAATGCGCAAGCATCTGAATGCGCATCATGGCATCAACGATGGCGTATCTGCGCATGCCAACGAGGTTTTTATCATACGCAAACTGCCCTATGAGTGTCCACGGTGCATACGTTCATTTGCGGCCAAACGCACGCTGACTCGCCATTTGCAACGTAGCCATTTGGTGGACACAATCATTGAGATGCAGGCGCCTCAATTGACAACTAGCTCAGCGGCCACCACGACCACATCGACGGCAACAACCACATTGCCGCTGAACGCCTGTGAtggcaataaaacaacaacaacagcaacaacaataacaacacaacTGGATTCTAACATGTTGGCGCCGCAAGACGCTGAGACTTTCcacggcgatggcgatggcgatgcaGATGGCGATGGAAAATGCGAAGAGAACGCGCTAGACAAGGAAACAGGATACAAAACGGAAAATTCAGATACATttatcaaaagcaaaacaacaacagcagcagcaacaacaacagcacaagaAACAAacgaagcagcaacaacagctatcACATCATTAGCTGAAAATACAGAAGCTGATTCAGTAACAGCGACAGATGCCGCagaagctgcaacaacaacaaccacaacagcaataacaacagctgaGAATTTgtcaacaacatcagcaacaactacaacaacaaccgcaggCTCTACGCTCTTTCCAACGCCCACGCCATTTGACTTTGATCTTGACTTTATTGGCAACGGTGCACAAGCTGACATGCCCATTAAGAATAACAATGACAGCTTTAACATTGCATCGAATTCCAGTCATCTCCTTAATGGCAGCGATAAACTGCTGTCTGCAGCGTTGGAGCCATCGCCAGTTAAGGATTTACGCACACGGCTGCCGCGTACACCCATCTTTGTGTGCAAGCAATGCAATCAGACCTTCGATGAGCTCGGCAAGCTGTTGCAGCACGAACTGGATCAACATTCCAGCGGCATTGTGTCGCCGCGCAGCAGTTACCAGCATCAGTGCAAGATCTGTAAGACCACATACCGTACCATAACGCTACTCAACTATCATATGAAACGGCATGCGCCAGTCAAACTTCCGTGTAAACAGTGCTCCAAGGAGTTTGAGGAGAGTTCGGATTTGGAACAGCATATACAGTCCGAGCATAGCACCAATTTGCCGCTGCAATGCGGTGTGGATGGTTGCACGAAGACATTCGCCTATAAACATCATCTGAAACGTCATCAGACAGCCTCCCATACGCCGGTTCAGTATATTTGCCCGGAGTGCGGATGCGATATGCTAACCAGTCTGCAGCTAAGGAATCACTTGTCCACGCACAAGGGTACACATTCCTACAAGTGTCCGAAATGCATGCGCACTTATTTGCGGCGAAAACCTTTTCGGAGACATGCGCTACGTGAGCACAAATGGGAGCTGACTGAGGaagaaattgataaaatatattgcgTAAATAGTCCATCGCCGTCAATCAAATTGCGTGAACGAAGATCGGTGAAGGCTGGGAATGACCGGTATGACTAG
Protein Sequence: MAHKRVKIENMAVNYKFACRCCLKSEAEFFKLDSLIDCGIGDNDATVTKIPLIRLLLFCMRTENLPELPQYICTECSKSLQIAYLFIQNGLRAHEILCRKLCPGQLKSTTRSNGQHMSLTQESEDATLGRHGELKSTKAAVRHECKVCGAIIYNRMELKQHIRMHTEASRHQCKLCKFVTLKHRQLPEHYRKAHGLTAAQIEHQLKIRKSMQAAANAITTSTAAATATTTAADDGQVKVCTLEDMELLIPTVLTPEDFSHPQLDAEQLRDIEQQLANSLPIPQSSSTYDMEPTIAAGGGPNVSIGTEFLVLPDGSLQQVNDGGVVFEYIDDSKNVANTATNMTLQSLLGDSKPDLTYDPMDIDLSHMVIDNALPQITVKPKPRPAPASTGALKHKCKLCPKAFPTVARLKSHQLTHSHLPKFYCDQCAYYSLRSSDLIQHYTTEHKSCVTESRVNHYEKLPGEKSRIYSCDMCLFEAPSSGQLRAHYSNKHMVVPSEVQLRPTWTHESRERVANSTLTDGNGSAQPDIPLGIKYPPMMSSETTTEPTSVSTTVIGQPAQATTTTVVTPDGDINVVVDATSLFYAAGAPDQLTTTEGTTKTTRTTASATNSNTFGLFPEQSFGNSIASTTTMSQEPNAVPSTTSTSNPNTSILGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEDVEVGEEDDDDEDDDAENEDENDNNNAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGDKVSVASTTIEKIQVNNDKPPMLMCAKCPFECELESEMRKHLNAHHGINDGVSAHANEVFIIRKLPYECPRCIRSFAAKRTLTRHLQRSHLVDTIIEMQAPQLTTSSAATTTTSTATTTLPLNACDGNKTTTTATTITTQLDSNMLAPQDAETFHGDGDGDADGDGKCEENALDKETGYKTENSDTFIKSKTTTAAATTTAQETNEAATTAITSLAENTEADSVTATDAAEAATTTTTTAITTAENLSTTSATTTTTTAGSTLFPTPTPFDFDLDFIGNGAQADMPIKNNNDSFNIASNSSHLLNGSDKLLSAALEPSPVKDLRTRLPRTPIFVCKQCNQTFDELGKLLQHELDQHSSGIVSPRSSYQHQCKICKTTYRTITLLNYHMKRHAPVKLPCKQCSKEFEESSDLEQHIQSEHSTNLPLQCGVDGCTKTFAYKHHLKRHQTASHTPVQYICPECGCDMLTSLQLRNHLSTHKGTHSYKCPKCMRTYLRRKPFRRHALREHKWELTEEEIDKIYCVNSPSPSIKLRERRSVKAGNDRYD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00598403;
90% Identity: iTF_00567783;
80% Identity: -