Dpar014150.1
Basic Information
- Insect
- Drosophila paracracens
- Gene Symbol
- zfh1
- Assembly
- GCA_035044025.1
- Location
- JAWNMN010000951.1:95946-100698[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 2.8e-05 0.0019 18.5 1.0 1 23 152 174 152 174 0.97 2 15 0.00087 0.057 13.9 1.2 3 23 182 202 180 202 0.94 3 15 9.5e-05 0.0062 16.9 0.1 1 23 364 386 364 386 0.98 4 15 0.00033 0.021 15.2 0.9 1 23 392 414 392 414 0.98 5 15 0.00012 0.0076 16.6 2.3 1 23 446 469 446 469 0.94 6 15 0.011 0.75 10.3 3.0 1 23 515 537 515 537 0.94 7 15 0.0042 0.28 11.7 0.4 1 23 543 566 543 566 0.98 8 15 0.028 1.8 9.1 0.4 3 19 575 591 574 592 0.95 9 15 0.00016 0.011 16.1 5.6 1 23 601 623 601 623 0.97 10 15 0.043 2.8 8.5 1.2 2 23 629 650 628 650 0.96 11 15 9.6e-06 0.00063 20.0 1.0 1 23 659 681 659 681 0.98 12 15 0.0011 0.072 13.5 0.1 3 23 689 709 687 709 0.97 13 15 5.8e-05 0.0038 17.5 0.5 1 23 715 737 715 738 0.95 14 15 0.049 3.2 8.3 0.4 1 23 748 770 748 770 0.97 15 15 0.0038 0.25 11.8 0.5 1 23 1280 1302 1280 1302 0.98
Sequence Information
- Coding Sequence
- ATGAACAATCCGGACTATGGCGGCATCCAGTGGATACAGCAGGAAAGCAGCGCCGTCGTCGACGACAGCGAAACAGAGATGACAGCAGCCTATTTGGTCAACGCTGCCGCCAATGGAAGCATTTCCAACGATGACGAGCTCGACCATATAGCAGCCGAGAATCTCATCTTTATGGCACGCGACCGCCAACTGAGCGAAATCATCGCCGCAAATGAGGCAAATGGCGGCAGCACCACAGTGCTAATCGCGGAGAGAGACGAAAATAACGGAGTGGAATACGCCGAGTCCTTTGACGATGATGCCCAAGTCGTCACCGAGGAGATCATCACGGATGATTGGGTCCAGCATCAGGGCGCAGAGCGtgTGGAAATTGCAGCAGAGCAAATCGCTGGCAACGGCAGCTCCCAGGAGCTGTTGGACATGCAACAGAATGAATATATGGCGATGCGTCCATATCCCTGTGACTTTTGCAGTCGACGCTTTCGCAAGAAGGCCAGCCTCAACAATCATATGCTGGCGCATCAGAATGATCGTCCCCATCTCTGCAAACTGTGCGGGGCGCGTTTCTCGCGACGTGCGGAGCTCATCAGTCACTTCAAGGCTCATGCGGAGGCCCAGGTGGCCGCCGATGAAGAGGCAGCTGCGGCAGCCATTAAATTtgagccacaacagcagctgcaaccgctgcaacagcagcagcagcgacaaattGATGATCATTTCTATGAGCAGGAATGGCCGCTGGTCGAGGAGCAGCTGTCGCAGatcgaggagcagcagcagcagcagctggagcagcttcAGCAGCGGTTGCAACATTCGGTTGTACCACCAACCGCTGCTCGTGGACGTATCAGTCGATTGAAACTCAAGGAGGAGAGCTCCCAATATATTGTGATTGCCTCCGATAAACCGGAGGCGGAGTTGCCTCAATACATGCATTGCGAGGCGAATGGCGATCAATCACttgccaccaacaacagccaagTCCAATCAACATCATCCAATgatgttgcaactgctgctgctactgacGGGGCAGAGGGACAGGCAACGCTGCGCTTTCCCGTGCTCGACGAGAGCAAACCGTTCGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCGCTCGTCTCCCACATCAAGAATCATCGCGTGGATTCGCCTTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAATTACAGTCTGCAGGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAATTCGGAATATGATCCCGCATCGGCGGGCGAGGAGGAAACGGCGAGTGAATCGGAAGCGGAACAGCTTTACGGTAATTTCTACTGCGGCGAATGCGGTATCTCCTTTCACCGGCAGGATTTGTTGCGGCgccacagcaaacagcagcacagcaagcagctggctgcaacaacagctggtggcaacaacaacaacagtgtggcaactgcaacagcaacggatGCAATGGGTGCTGCagatgcaactgcaactgatgccgatgctgatgaTTCCAAAGATGCGACACATTGTTGCCACACGTGCGGCAAATCATTTCCCAGCGTACTCAAACTCCTCGCCCATGCCGAAATCCACAAACGCTTCCCGCCATTCAAATGTGTGCTGTGCGGAGTCAGCTTCTACGAGGAGCAGGCGATAAAGCGGCACCTGAACACGCGGCATCCGCACGAGCTGAAGCCCAAttcgtgtgtgttgtgtggcaAGGAGTGTCGCGATCGGAAGGCGCTGATCAAACATGCGTGGGATCATTCGCGAGAGAAGTGCCACTCGTGCTCCAAGTGTGGCAAGAATTTCCACAACAAGGCGCGCCTGAAGCGACACATGGCATCGCATCGCGACAAGTCCGTCGTGTGCGAAGTGTGCCACGAGGAGTTCCCCGATGGACGCACTTTGTCCAATCATCGGCATTCCCACAGCACAACGTCGCCGGGCAAACTCTTTCCCTGCCACGAGTGTGGCAAGACTTTTGGGTCACGCAGCTCGCAACAGATTCATGTGCGCATCCACACGGGTGAAAGGCCCTACGGTTGTCGCTACTGCTGGAAGGCCTTCGCCGACGGCGGCACTCTCCGCAAACACGAACGCATCCATACGGGCGAGAAGCCCTATGCATGCTCCGTCTGCCCGCGTGCCTTCAATCAGCGTGTCGTCTTGCGGGAACACATCCGGTCGCATCATTCCGGTCTGGATGCGGCACGTGGCACGTATCATTGCACGGTCTGCTCGGCGGATTTGAGCTCATCGAATGACCTCATCCAGCATCTCATCCAGCACAGCGATACGAACACAGCCAAACAGCGACAGCCAATTaCTGGTCCACGTAAATACAAACGTCGCCGGAAACTGCAGCCGCATGAGATTGCGCACATGCGCGCCGAGCACAAGGCTGGCGGCGGGGATGGCGAGGCTGGCGAGGAGGAGGATTATGCCAGCGACTTGGACTACTGCCATCTGGATGTGGAGAATGTGGATGAACTGCTGCAGGAGGCAACCGCAGAGCCACCATCACCCACCAAGAAAGCGAAACGCAAACGCAAAGCGCCAATTAAAACCGGTGATGAGCAAAGATTGTGGGATGAGAAATTCCCGCAGCAGGCGAGCAATGGGAATAGCGATGAGGCCTACAAGAGTTTCTTCCAAATGGACTCAATGGTCGTGGTCAATGATCAAACGTTGCAGCCCGTTGATGCTGGTGTTGCCTCGACCAAGTTGCACCAGGCGGAGATTAAGGAGCAAACGCTGAAGACAGGCAATCGCAGTAGCAAAAGAAGGGCAGGTAAAGCTGGGGGAGGAGGAACAGGCGCAgcaagaggaggaggagctgctgctactgctgctccaCGTCCCCGGATGATACATACGGCCAAGTCGCAGCAGACAACGGCAAGGAAATCCCGCACAAGGAGTTATGTCACACGCACCAGCAccaatgagcagcagcaggggggAGGAGCAAGTGGGGGAAGCCTCATCAAATCCCGGATTGTGGATGACTACGAGATCATCTCCCCGGCCACACAGCCACCCAATCAGATCAGCTCCAGTCCGCTGCACATCaaacaggagcaggaacatcaactgcatcatcatcatcatcatcagcatcagcatcatcagcagcagcagcagagagtcCAACTGCTCTTCGATGACAGCCATCTGCTCATCGATGCGGGCCTGTTGCGTGAGAAGACCTACGAGAAATATAATCCCAGCATTGTCCAAGATCTCGAAGAGATTTTGCGTAGTCCCCCGAAGCATGAGCGGAACGATCGACGGCTGCGCTTCACAAGCGAATCGTCGACGACGCCACAATTTCTGCCCGGCGAGGAGGAGGAACAGCATCTCATCAAGATCGAGCCCACGTCGCCGGATCTCCGCGAAATGGTCGAGACCCAGCAGCCAGCGGCACTGCCCACATCTTCCTCCGCCTGCTCAACGGCAGCACGCACTTCCCGCCACCTGCGACAACTGACTGCCAATGGTTCCAGTTCCATTTCCACTGCCACATCCAGCTCCAGTGGCCCTCCAAGTACGCGAGCCGCTTCCAAGCGCATTGCCAGCAAACAGCTTTCCAAGAAATCCActtccaacagcaacaaaggcaaCGCATCATCGTCTTATCTCAGCTATGGCGTCGACTCCTAtaatgtgggcgtggcaaccaGTGCCAATAGCTCCTCGGATGTCAGTTCCGGTTTCTTCTCCATTTCCGAGGTTGTCTCGGCGGCGGATGCAGCCGATGCAGCTGCgaaggcggcggcggcagcagccagcaaaacGGAGCGAAGAACGCGCTGCTTTGAGTGCGAAATGTGCTCGTCCTATTTCCCAGATCGCGCCCAGCTGCTGgaacacatgcacatacacatctAA
- Protein Sequence
- MNNPDYGGIQWIQQESSAVVDDSETEMTAAYLVNAAANGSISNDDELDHIAAENLIFMARDRQLSEIIAANEANGGSTTVLIAERDENNGVEYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQVAADEEAAAAAIKFEPQQQLQPLQQQQQRQIDDHFYEQEWPLVEEQLSQIEEQQQQQLEQLQQRLQHSVVPPTAARGRISRLKLKEESSQYIVIASDKPEAELPQYMHCEANGDQSLATNNSQVQSTSSNDVATAAATDGAEGQATLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGEEETASESEAEQLYGNFYCGECGISFHRQDLLRRHSKQQHSKQLAATTAGGNNNNSVATATATDAMGAADATATDADADDSKDATHCCHTCGKSFPSVLKLLAHAEIHKRFPPFKCVLCGVSFYEEQAIKRHLNTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAARGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKAGGGDGEAGEEEDYASDLDYCHLDVENVDELLQEATAEPPSPTKKAKRKRKAPIKTGDEQRLWDEKFPQQASNGNSDEAYKSFFQMDSMVVVNDQTLQPVDAGVASTKLHQAEIKEQTLKTGNRSSKRRAGKAGGGGTGAARGGGAAATAAPRPRMIHTAKSQQTTARKSRTRSYVTRTSTNEQQQGGGASGGSLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQLHHHHHHQHQHHQQQQQRVQLLFDDSHLLIDAGLLREKTYEKYNPSIVQDLEEILRSPPKHERNDRRLRFTSESSTTPQFLPGEEEEQHLIKIEPTSPDLREMVETQQPAALPTSSSACSTAARTSRHLRQLTANGSSSISTATSSSSGPPSTRAASKRIASKQLSKKSTSNSNKGNASSSYLSYGVDSYNVGVATSANSSSDVSSGFFSISEVVSAADAADAAAKAAAAAASKTERRTRCFECEMCSSYFPDRAQLLEHMHIHI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00542584;
- 90% Identity
- iTF_00499722;
- 80% Identity
- -