Dpar012711.1
Basic Information
- Insect
- Drosophila paracracens
- Gene Symbol
- sba
- Assembly
- GCA_035044025.1
- Location
- JAWNMN010000773.1:1727381-1734712[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 0.93 1.6e+03 -1.3 0.1 29 49 140 161 125 186 0.70 2 2 8.1e-09 1.4e-05 24.6 0.0 9 58 242 282 235 303 0.81
Sequence Information
- Coding Sequence
- ATGGCTGCCGCATCCGCtggccaacagctgcagcagcagcagcagcaacaacagactcagcacaaattgaacattgttggtgttggcaaTGCGGAGACGGTTGCTGGTGTGCTGCAGGTCAACAAtgagttgcaacagcaacagcaacagctcaacatgtacaagcaacagcagcaacagcaattgttgcagcaacagcaacatcaattcTATCAGCAGCAAACGAAATTTGTATCGCGGGTCGTTACAAATGCAGCCGCaatgcaaccacaacaacaacagcagcaacaaatattacCAGCTGGTTTGGTAAATGGCAGCGCCAACATGATGCAAGCCACAAATGTTGCtgtacagcagcagcagcaccaacaacatcagcagcaacaacaacaacagcagcaacaacaacaactgcgtcAAAGTcaacacatttttgtgtgtccATCAATAGGCAcgcagctacagcaacagcaacaacagcagcagcagcaacttcaacagcagcagcaaagcaaacagcGTTTAGCGCAAATCAAGTTGCCTGTAAAgtccgcagcagcagtcgcaacagcaactgttggtGCCGCGCACTGTatgccagcaacaattgcaatgcgTCAAATGAATCAGaaccatcagcaacagcagctctaTGCTAAGAATgtggccaaaaacaataatgctggtaacaacatcaacatgaacagcaacagcaacaatgcaaatttggCTCCTGGCTGGCGTCGactaaccaacaacaatgaagtGGCCTACATCAGTCCAACGGGCAAAACGCTGCGTACACAATTCCAAATTAAGGACTATTTGCTAACACAGGGTACCTGCAAGTGCGGCCTGCCGTGTCCGCTGAGGCCGGAATACTTTTTCGATTTTAATGCACAGGTAAGTTAG
- Protein Sequence
- MAAASAGQQLQQQQQQQQTQHKLNIVGVGNAETVAGVLQVNNELQQQQQQLNMYKQQQQQQLLQQQQHQFYQQQTKFVSRVVTNAAAMQPQQQQQQQILPAGLVNGSANMMQATNVAVQQQQHQQHQQQQQQQQQQQQLRQSQHIFVCPSIGTQLQQQQQQQQQQLQQQQQSKQRLAQIKLPVKSAAAVATATVGAAHCMPATIAMRQMNQNHQQQQLYAKNVAKNNNAGNNINMNSNSNNANLAPGWRRLTNNNEVAYISPTGKTLRTQFQIKDYLLTQGTCKCGLPCPLRPEYFFDFNAQVS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00513461;
- 90% Identity
- iTF_00528044;
- 80% Identity
- -