Basic Information

Insect: Drosophila niveifrons
Gene Symbol: PRDM5
Assembly: GCA_035046325.1
Location: JAWNOC010000036.1:2554870-2557103[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.042 2.7 8.6 3.0 2 23 344 366 343 366 0.96

2 10 1.1 72 4.1 0.4 6 23 376 393 376 393 0.98

3 10 0.0016 0.1 13.0 0.4 1 23 399 421 399 421 0.97

4 10 0.0016 0.11 13.0 0.4 1 23 432 455 432 455 0.86

5 10 3.6e-05 0.0023 18.2 0.9 1 23 463 486 463 486 0.97

6 10 8.9e-05 0.0057 17.0 0.4 3 22 494 513 492 515 0.88

7 10 0.0078 0.5 10.9 0.3 2 23 527 549 526 549 0.97

8 10 0.00027 0.018 15.4 5.7 1 23 556 579 556 579 0.93

9 10 2.4e-06 0.00016 21.9 1.2 1 23 585 607 585 607 0.98

10 10 5.8e-05 0.0038 17.5 1.4 1 23 613 636 613 636 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.042	2.7	8.6	3.0	2	23	344	366	343	366	0.96
2	10	1.1	72	4.1	0.4	6	23	376	393	376	393	0.98
3	10	0.0016	0.1	13.0	0.4	1	23	399	421	399	421	0.97
4	10	0.0016	0.11	13.0	0.4	1	23	432	455	432	455	0.86
5	10	3.6e-05	0.0023	18.2	0.9	1	23	463	486	463	486	0.97
6	10	8.9e-05	0.0057	17.0	0.4	3	22	494	513	492	515	0.88
7	10	0.0078	0.5	10.9	0.3	2	23	527	549	526	549	0.97
8	10	0.00027	0.018	15.4	5.7	1	23	556	579	556	579	0.93
9	10	2.4e-06	0.00016	21.9	1.2	1	23	585	607	585	607	0.98
10	10	5.8e-05	0.0038	17.5	1.4	1	23	613	636	613	636	0.97

Sequence Information

Coding Sequence: ATGGCTGCAtgtgtgctttgctttgaaCTCTGCAAGAACGGACAGTCCTATAAGATATTTTCCGAAACGGGTTTGCGGCtgaatatttgcaaaacaataaacaaacatttctgGCTTGAATTAAACAGTGTAACTGGCAGCAGTGAGGAGATCTGCAATCAATGCTGGAAGTGTGTGAACAGCTTCAATGTCTTCTACCAACGCGTCTATAATGTCCACCAAGAACGACGTGAATTCAAAGATGTGCCCATTGAGTTCTGCGTGGAAACTGAGGCGGCTGCCAATCCGCTGGCACTTGCCACCGAATTGGATGCACTCGACGAGGCATTCTTTGCCGCGGGAAGCGTTAAAGTCGAGGTGAACGAGCTGGAACCATTGCCCAAGCTAGAAATTTTGGAAGAGCCAGCGCCCCAGCCAATAAAAGGTACGAAGCGAGCTACTGCCGCTGCCTCTGaaacgccagcagcagccaagcgaCGTATCAAACGCGAAAAGGTAACGCTGCCCAGCGACTCCGATGGCGACATTCCACTAGCCGAGTTCCTGGACAACAAGCACAATGGCAAAGCGGAGCAAAAAGAGACGCCAACCCAGGGTAGACAGTTGCGTCGCAGTGTTCGACGTGGTCGCCCACCGAAAAAACCGAGAACACCGTCACCAGAATCACCCCCACCAGCTACCGAGGCACCTCTGAAAAAAGAATTGGATTCAGATGATGAGCTAGATGATATCATGGATTGCAGGGAAGATGATAGGGAGTTTGTGCCGGCTGAAGCTGTGCTGGGGACCGATGACAGCGCAAGTTCCAGCGAGAGTAGCGACGGCGACTCCGGCGACAGTTTACCGGACTTTGTTCCCGAGGAGCGTTACGCTGAGATTCCCAAACGCGTTGTGGTAAAGCCCAAGAAGTATCGCAAGCGTCCCAAGCCCTTGGTTCCGCCGGTGCGCATGAGTCGCGAAGAGATCGAACGGCGCAAGGAGgagcaaaacaaattcgatgagattatatttgatttcttcAAGAAATTGCAATGTCACATCTGCAACGAGTTGGTGCACAACTTCGGAGACATGCGACGCCATCAACGCATGTCCCACAACATGGAGAGTGGCTTCATCTCGTGCTGTGGCCGCAAGTTTCACATGCGTCGCGGCTTAGCCGAGCACGTGCTAGTCCATAAAAATCCCGATCACTTTACGTGTAAGCAGTGTAATCGTGCATTCCTGGACTCCAGATCTCTAGAGGCGCACGAGGTGACACATACAGAGGCAGATCCGAAGGAGAAACCCACCTATACGTGCGACAAGTGTCCCAAGATCTTTACCACAAAGGCGGCTGCGGAATATCACAATGCATCCAAGCATGTGGATAAGTCGGACTTCAAGTACACCTGTCCTGAGTGCAACAAGAAAGTGCCCACGGAACGCAAGCTGAAGCAGCATTTGCGTTACATGCACGATCCGGAGAAGGCCATTATCTGTGACAAGTGCGGCAAAACTTTGCGCTCCCGGGCGAATCTCAAGAAGCACAATGAGCTCGAGCATTCCGACAAGCCTCGTCCCAAACCGGAGCCAGTGCAGTGTGAGATTTGCGGCACTTGGTTGCGCCATGTGTCCGGTCTTAAGCAGCACATGAGCACGGTACACGAACCGCCTGGAACAGTGCATCGTTGTCACATCTGCGACAAGACATCCACCAATGCTCGCGCGCTGAAACGTCACATTTACCATAACCATCAATGCGAGCGCAAATTCCGCTGCACGATGTGCGAGAAAGCATTCAAGAGGCCGCAGGATTTGCGAGAGCACACATCCACGCACACGGGCGAGGTTCTTTACACTTGCCCCAACTGTCCGCAGACATTCTTCTCGAATGCCAACATGTACAAGCATCGCCAACGTTTGCATCGCGCCGAATGGGAGGCGGATCGCAAGAAACCTCTGCCACCTAACATCATGCAACAATCAAGCAACAAGAAACGCCAGTCAACCACAAATGCTTCACCTGGCACATTATTTGCCCAAGTCGTTGAGGCTGCGACGATTTCCAATAAACAGTAG
Protein Sequence: MAACVLCFELCKNGQSYKIFSETGLRLNICKTINKHFWLELNSVTGSSEEICNQCWKCVNSFNVFYQRVYNVHQERREFKDVPIEFCVETEAAANPLALATELDALDEAFFAAGSVKVEVNELEPLPKLEILEEPAPQPIKGTKRATAAASETPAAAKRRIKREKVTLPSDSDGDIPLAEFLDNKHNGKAEQKETPTQGRQLRRSVRRGRPPKKPRTPSPESPPPATEAPLKKELDSDDELDDIMDCREDDREFVPAEAVLGTDDSASSSESSDGDSGDSLPDFVPEERYAEIPKRVVVKPKKYRKRPKPLVPPVRMSREEIERRKEEQNKFDEIIFDFFKKLQCHICNELVHNFGDMRRHQRMSHNMESGFISCCGRKFHMRRGLAEHVLVHKNPDHFTCKQCNRAFLDSRSLEAHEVTHTEADPKEKPTYTCDKCPKIFTTKAAAEYHNASKHVDKSDFKYTCPECNKKVPTERKLKQHLRYMHDPEKAIICDKCGKTLRSRANLKKHNELEHSDKPRPKPEPVQCEICGTWLRHVSGLKQHMSTVHEPPGTVHRCHICDKTSTNARALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMQQSSNKKRQSTTNASPGTLFAQVVEAATISNKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00556715; iTF_00472565; iTF_00553911; iTF_00595430; iTF_00509285; iTF_00614379; iTF_00520818; iTF_00589726;
90% Identity: iTF_00556715; iTF_00472565; iTF_00553911;
80% Identity: -