Basic Information

Insect: Drosophila rubida
Gene Symbol: ZNF574
Assembly: GCA_035046165.1
Location: JAWNOF010000021.1:36564201-36566419[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.02 1.2 9.5 2.2 2 23 334 356 333 357 0.95

2 10 0.71 42 4.7 0.4 6 23 366 383 366 383 0.98

3 10 0.00014 0.0082 16.3 1.1 1 23 389 411 389 411 0.98

4 10 0.00046 0.027 14.7 0.9 1 23 424 447 424 447 0.90

5 10 5.3e-05 0.0031 17.7 0.7 1 23 455 478 455 478 0.97

6 10 2.6e-05 0.0015 18.6 1.0 3 23 486 507 484 507 0.92

7 10 0.0066 0.39 11.1 0.4 2 23 519 541 518 541 0.97

8 10 0.0017 0.1 12.9 7.5 1 23 548 571 548 571 0.93

9 10 2.4e-06 0.00014 21.9 1.2 1 23 577 599 577 599 0.98

10 10 5.8e-05 0.0034 17.5 1.4 1 23 605 628 605 628 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.02	1.2	9.5	2.2	2	23	334	356	333	357	0.95
2	10	0.71	42	4.7	0.4	6	23	366	383	366	383	0.98
3	10	0.00014	0.0082	16.3	1.1	1	23	389	411	389	411	0.98
4	10	0.00046	0.027	14.7	0.9	1	23	424	447	424	447	0.90
5	10	5.3e-05	0.0031	17.7	0.7	1	23	455	478	455	478	0.97
6	10	2.6e-05	0.0015	18.6	1.0	3	23	486	507	484	507	0.92
7	10	0.0066	0.39	11.1	0.4	2	23	519	541	518	541	0.97
8	10	0.0017	0.1	12.9	7.5	1	23	548	571	548	571	0.93
9	10	2.4e-06	0.00014	21.9	1.2	1	23	577	599	577	599	0.98
10	10	5.8e-05	0.0034	17.5	1.4	1	23	605	628	605	628	0.97

Sequence Information

Coding Sequence: ATGGCTGcctgtgtgctgtgctttgAACGCTGCAAGATCGGCCAGTCCTATAAGATATTTTCCGAAGAGGGTTTGCGGCtgaatatttacaaaactataaacaaacatttctgGCTCGAATTAAACATTGCGACTGGCATTAGCGAGGAGATCTGTAAACAGTGCTGGGAATGCGTAAACAGCTTTAACGCGTTCTACCAACGCGTCTATCTAGTGCATCAAGAACGACGCGAGCTCAAAGATGTGCCCATTGAGTTCTGCGTCGCAACGGAGGCGGCGGCGAATCCACTGGCACTTGGCACTGAATTGGATGCACTCGACGAGGAGTTCTTTGCCACTGGCAGCATAAAAGTCGAAGTAAACGAACTGGAACCATTGCCCAAACTGGAAGTTCTCGAACAGCCAGCGACTGAGGAAACGAAAGCCATTaaacgagctgctgctgccgacacgCCGACGACTGCAAAGCGGCGCATCAAACGCGAACAGCAAACGCTTGTCAGCGACTCCGATGGCGATATTCCACTAGCCGAGTTCCTCGACATTAAGCAAAATGGTAAAGCGGTGCATGCAGAAACGCCAGCCAAGGGCAGACAGCTGCGTCGAAGTACTCGTGGTCGTGGGCGTCCACCGAAGAACCCTAAGACGCCGCCCGAATCACCGCCAGCCAGTCTAAAGAAAGAAGTGGATTCGGATGATGAGTTGGACAACCTGGACAACGACATGGAGTTTGTGCCGGCTGAAGCGGTGCTTGGCACAGATGACAGCGAAAGTTccagcgagagcagcgacagcgacaccgGTGACAGCTTGCCAGACTTTGTGCCCGAGGAGCGCTTCGCAGAGATTCCCAAACGCGTAGTGGTCAAGCCCAAGAAGTATCGCAAACGTCCCAAGCCATTGGTGCCGCCGGTGCGCATGAGTCGCGAAGAGATCGAGAAACGGAAGGCGCAACAAACCGAATTCGATGAGATTATATTTGACTTTTTCAAGAAACTGCCCTGCCACATCTGCAACGTGTTGGTGCGCAATTTCGGGGATATGCGACGCCACCAGCGCATGTCTCACCACATGGAAAGTGGTTTCATCTCTTGCTGTGGTCGCAAGTTTCATATGCGCCGCGCATTGGCCGAGCACGTGCTAGTCCACAAGAATCCCGAGCATTTTATGTGCACGCAATGCAGTCGTGTGTTCCAAGACTCCAAATCCCTGGAGACGCACGAGCTAACGCACACCAATCCCAAGACAGATACGAAGGAGAAGCGAACTTATCAGTGCGACAAGTGTCCCAAGTTCTTCACCACAAAGGCGGCGGTCGAGTATCACAATGCATCGAAGCATGTACCCAAGTCGGACTTCAAGTACACCTGCCCCGAGTGCAACAAGAAGGTGCCCACAGAGCGTAAGCTGAAGGAACATCTGCGCTACATGCACGATCCGGAAACTGCCATCATCTGTGACAAGTGCGGCAAAACGTTACGTTCGCAAGCGAATCTTAAGAAGCACCATGAGCTCGAACATTCCGACACGCCACGTCCCAAGCCCGACCCCGTGCAATGCGAGATTTGCGGCACCTGGCTGCGTCACATGTCTGGCCTGAAGCAGCACATGAGCACGGTCCACGAGCCGCCTGGAGAGGAGCATCGCTGTCACATCTGCAACAAGAAGTCCACCAATTCGCGAGCACTCAAACGACATATTTACCATAACCACCAATGCGAGAGAAAGTTCCGCTGCACCATGTGCGAGAAAGCATTCAAGCGGCCGCAGGATTTGCGGGAGCACACATCCACGCACACGGGCGAAGTGCTGTACACCTGTCCCAACTGCCCGCAGACATTCTTTTCGAACGCCAACATGTACAAGCATCGCCAGCGTCTGCATCGTGCGGAATGGGAAGCGGATCGCAAGAAACCCCTGCCACCCAACATAATGCAGCAAGCGGTGGGCGCCACGTCAGCGATGAAGAAACGACAGTCCACCAATGCCGGACCTGGCCTATTCACACAAACCGACGAGGCTGCTGCGAGTTCCAACAAACAGTAG
Protein Sequence: MAACVLCFERCKIGQSYKIFSEEGLRLNIYKTINKHFWLELNIATGISEEICKQCWECVNSFNAFYQRVYLVHQERRELKDVPIEFCVATEAAANPLALGTELDALDEEFFATGSIKVEVNELEPLPKLEVLEQPATEETKAIKRAAAADTPTTAKRRIKREQQTLVSDSDGDIPLAEFLDIKQNGKAVHAETPAKGRQLRRSTRGRGRPPKNPKTPPESPPASLKKEVDSDDELDNLDNDMEFVPAEAVLGTDDSESSSESSDSDTGDSLPDFVPEERFAEIPKRVVVKPKKYRKRPKPLVPPVRMSREEIEKRKAQQTEFDEIIFDFFKKLPCHICNVLVRNFGDMRRHQRMSHHMESGFISCCGRKFHMRRALAEHVLVHKNPEHFMCTQCSRVFQDSKSLETHELTHTNPKTDTKEKRTYQCDKCPKFFTTKAAVEYHNASKHVPKSDFKYTCPECNKKVPTERKLKEHLRYMHDPETAIICDKCGKTLRSQANLKKHHELEHSDTPRPKPDPVQCEICGTWLRHMSGLKQHMSTVHEPPGEEHRCHICNKKSTNSRALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMQQAVGATSAMKKRQSTNAGPGLFTQTDEAAASSNKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00562653;
90% Identity: iTF_00595430; iTF_00520818; iTF_00509285; iTF_00614379;
80% Identity: -