Basic Information

Insect: Drosophila nasuta
Gene Symbol: PRDM5
Assembly: GCA_017165715.1
Location: Scf:8798-12653[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.034 2.2 8.6 3.0 2 23 345 367 344 367 0.96

2 10 0.91 58 4.1 0.4 6 23 377 394 377 394 0.98

3 10 0.00045 0.029 14.5 0.5 1 23 400 422 400 422 0.98

4 10 0.0013 0.085 13.0 0.4 1 23 433 456 433 456 0.86

5 10 2.9e-05 0.0018 18.2 0.9 1 23 464 487 464 487 0.97

6 10 7.2e-05 0.0046 17.0 0.4 3 22 495 514 493 516 0.88

7 10 0.0064 0.4 10.9 0.3 2 23 528 550 527 550 0.97

8 10 0.00035 0.022 14.8 4.8 1 23 556 579 556 579 0.93

9 10 2e-06 0.00013 21.9 1.2 1 23 585 607 585 607 0.98

10 10 4.8e-05 0.003 17.5 1.4 1 23 613 636 613 636 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.034	2.2	8.6	3.0	2	23	345	367	344	367	0.96
2	10	0.91	58	4.1	0.4	6	23	377	394	377	394	0.98
3	10	0.00045	0.029	14.5	0.5	1	23	400	422	400	422	0.98
4	10	0.0013	0.085	13.0	0.4	1	23	433	456	433	456	0.86
5	10	2.9e-05	0.0018	18.2	0.9	1	23	464	487	464	487	0.97
6	10	7.2e-05	0.0046	17.0	0.4	3	22	495	514	493	516	0.88
7	10	0.0064	0.4	10.9	0.3	2	23	528	550	527	550	0.97
8	10	0.00035	0.022	14.8	4.8	1	23	556	579	556	579	0.93
9	10	2e-06	0.00013	21.9	1.2	1	23	585	607	585	607	0.98
10	10	4.8e-05	0.003	17.5	1.4	1	23	613	636	613	636	0.97

Sequence Information

Coding Sequence: ATGGCTACATGTGTGCTTTGCTTTGAACGCTGCAAGAACGGACAGTCCTATAAGATATTTTCCGAAACAGGTTTGCGGCTGAATATTTGCAAAACAATAAACAAACATTTCTGGCTTGAATTAAACAGTGTAACTGGGAGCAGTGAGGAGATCTGCAATCAATGCTGGGAGTGTGTGAACACCTTCAATGTTTTCTACCAACGCGTCTATCATGTGCACCAAGAACGGCGTGAGTTCAAAGATGTGCCCATTGAGTTCTGCGTGGAAACTGTGGCGGCTTCCAATCCTCTGGCACTTGCCACCGAATTGGATGCACTCGACGAAGCATTTTTTGCCACGGATAATGTTAAAGTTGAAGTAAACGAGTTAGAACCATTGCCCAAGCTGGAAATTTTGGAAGAGCCAGCGCCCCAACCAACAAAAGGCACTAAACGAGCTACAGCCGCTGCCGCTGAAACGCCGGCAGCAGCCAAGCGACGCATCAAACGCGAGAAGGTAACGCTTCCTAGCGACTCCGATGGCGACATTCCACTAGCCGAGTTCCTGGACATCAAGCACAATGGCAAAGCGGAGCAAAAAGAGACGCCAACCCAGGGCAGACAGTTGCGTCGTAGTGCTCGTCGTGGTCGCCCACCGAAAAAACCGAGAACACCATCACCAGAATCACCGCCACCAGCCACCGAAGCATCTCTGAAAAAAGAATTGCATTCAGATGATGACCTAGATGATGACATGGATGACAGGGATGATGATAGGGAGTTTGTGCCAGCTGAAGCTGTGCTGGGAACCGATGATAGCGAAAGTTCCAGCGAGAGTAGCGACGGCGGCGGCTCCGGCGACAGTTTACCGGACTTTGTGCCCGAGGAGCGTTACGCTGAGATTCCCAAACGCGTTGTGGTCAAACCCAAAAAGTATCGCAAACGTCCCAAGCCCTTGGTTCCGCCGGTGCGCATGAGTCGGGAAGAGATCGAGCGACGCAAGGAAGAACAAAACAAATTCGATGAGATTATATGTGATTTCTTCAAGAAATTACAATGTCACATCTGCAACGAGTTGGTGCACAACTTTGGGGACATGCGACGCCATCAACGCATGTCCCACAACATGGAGAGTGGATTCATCTCATGCTGTGGCCGCAAGTTTCACATGCGTCGCGGTTTAGCCGAGCACGTGTTAGTCCATAAAAATCCCGATCACTTTACGTGTAAGCAGTGCAATCGTGCATTCCTGGACTCCAGATCTCTAGAGGCGCACGAGCTGACGCACACGGATCCCAAGGAGAAGGAAAAGCGCACCTATACGTGCGACAAATGTCCCAAGATCTTTACCACAAAGGCGGCTGCGGAATATCATAATGCATCCAAGCATGTGGATAAGTCGGACTTCAAATACACCTGTCCTGAGTGCAACAAGAAAGTGCCCACGGAACGCAAGCTGAAGCAGCATTTGCGTTACATGCACGATCCGGAAAAGGCCATTATCTGTGACAAGTGCGGTAAGACTTTGCGCTCCCGAGCGAATCTCAAGAAGCACAATGAGCTCGAGCATTCCGATAAGCCTCGTCCCAAACCGGAGCCAGTGCAATGTGAGATTTGCGGCACTTGGTTGCGTCATGTTTCCGGTCTTAAGCAGCACATGAGCACGGTACACGAACCGCCTGGAAACCATCGTTGTCACATTTGCGACAAGACTTCAGTTAATGCCCGCGCACTGAAACGTCACATTTACCACAACCATCAATGCGAGCGCAAATTCCGCTGCACGATGTGCGAGAAAGCATTCAAGAGGCCACAGGATTTACGAGAACACACATCCACGCACACGGGCGAAGTTCTTTACACTTGTCCGAACTGTCCGCAGACATTCTTCTCGAATGCAAACATGTACAAGCATCGCCAACGTTTGCATCGCGCCGAATGGGAGGCGGATCGCAAGAAACCGCTGCCACCTAACATCATGCAACAATCAAGTAACAAGAAACGCCAGTCAACTACAATTGCTACACCCGGCGCATTATTTGCCCAAGTCGTTGAGGCTGCGGCGAGTTCCAACAAGCAGTAG
Protein Sequence: MATCVLCFERCKNGQSYKIFSETGLRLNICKTINKHFWLELNSVTGSSEEICNQCWECVNTFNVFYQRVYHVHQERREFKDVPIEFCVETVAASNPLALATELDALDEAFFATDNVKVEVNELEPLPKLEILEEPAPQPTKGTKRATAAAAETPAAAKRRIKREKVTLPSDSDGDIPLAEFLDIKHNGKAEQKETPTQGRQLRRSARRGRPPKKPRTPSPESPPPATEASLKKELHSDDDLDDDMDDRDDDREFVPAEAVLGTDDSESSSESSDGGGSGDSLPDFVPEERYAEIPKRVVVKPKKYRKRPKPLVPPVRMSREEIERRKEEQNKFDEIICDFFKKLQCHICNELVHNFGDMRRHQRMSHNMESGFISCCGRKFHMRRGLAEHVLVHKNPDHFTCKQCNRAFLDSRSLEAHELTHTDPKEKEKRTYTCDKCPKIFTTKAAAEYHNASKHVDKSDFKYTCPECNKKVPTERKLKQHLRYMHDPEKAIICDKCGKTLRSRANLKKHNELEHSDKPRPKPEPVQCEICGTWLRHVSGLKQHMSTVHEPPGNHRCHICDKTSVNARALKRHIYHNHQCERKFRCTMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPQTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMQQSSNKKRQSTTIATPGALFAQVVEAAASSNKQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00562653;
90% Identity: iTF_00562653;
80% Identity: -