Basic Information

Insect: Drosophila nigromelanica
Gene Symbol: hang
Assembly: GCA_004149445.1
Location: SCDR01000168.1:117161-128292[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.27 33 5.8 1.0 3 23 459 480 458 480 0.93

2 17 0.79 94 4.3 3.2 3 22 587 606 585 606 0.89

3 17 0.00059 0.07 14.2 3.3 1 22 708 729 708 731 0.90

4 17 0.067 8.1 7.7 0.1 2 21 743 762 742 763 0.93

5 17 0.00068 0.081 14.0 0.2 2 23 899 921 898 921 0.95

6 17 0.002 0.23 12.5 0.1 1 23 929 952 929 952 0.96

7 17 0.00015 0.018 16.0 0.2 2 23 1039 1060 1038 1060 0.97

8 17 0.00028 0.034 15.2 2.9 2 23 1169 1191 1168 1191 0.97

9 17 0.022 2.6 9.2 0.2 2 23 1200 1222 1199 1222 0.95

10 17 0.00087 0.1 13.6 0.2 1 23 1235 1258 1235 1258 0.97

11 17 0.00012 0.015 16.3 1.1 1 23 1301 1323 1301 1323 0.99

12 17 0.0019 0.23 12.6 0.9 1 23 1331 1354 1331 1354 0.96

13 17 0.066 8 7.7 0.4 2 19 1362 1379 1362 1380 0.94

14 17 2.6e-05 0.0031 18.4 0.4 3 23 1477 1497 1476 1497 0.98

15 17 0.0049 0.59 11.3 0.1 1 23 1532 1554 1532 1554 0.97

16 17 0.00059 0.071 14.1 0.7 2 23 1640 1662 1639 1662 0.93

17 17 0.0063 0.75 10.9 0.3 3 23 1718 1738 1718 1738 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.27	33	5.8	1.0	3	23	459	480	458	480	0.93
2	17	0.79	94	4.3	3.2	3	22	587	606	585	606	0.89
3	17	0.00059	0.07	14.2	3.3	1	22	708	729	708	731	0.90
4	17	0.067	8.1	7.7	0.1	2	21	743	762	742	763	0.93
5	17	0.00068	0.081	14.0	0.2	2	23	899	921	898	921	0.95
6	17	0.002	0.23	12.5	0.1	1	23	929	952	929	952	0.96
7	17	0.00015	0.018	16.0	0.2	2	23	1039	1060	1038	1060	0.97
8	17	0.00028	0.034	15.2	2.9	2	23	1169	1191	1168	1191	0.97
9	17	0.022	2.6	9.2	0.2	2	23	1200	1222	1199	1222	0.95
10	17	0.00087	0.1	13.6	0.2	1	23	1235	1258	1235	1258	0.97
11	17	0.00012	0.015	16.3	1.1	1	23	1301	1323	1301	1323	0.99
12	17	0.0019	0.23	12.6	0.9	1	23	1331	1354	1331	1354	0.96
13	17	0.066	8	7.7	0.4	2	19	1362	1379	1362	1380	0.94
14	17	2.6e-05	0.0031	18.4	0.4	3	23	1477	1497	1476	1497	0.98
15	17	0.0049	0.59	11.3	0.1	1	23	1532	1554	1532	1554	0.97
16	17	0.00059	0.071	14.1	0.7	2	23	1640	1662	1639	1662	0.93
17	17	0.0063	0.75	10.9	0.3	3	23	1718	1738	1718	1738	0.98

Sequence Information

Coding Sequence: ATGAACGCCCGGATTGCTTTGGCAATCGGCAAAGAAAACTCAAACTACCGCTGGCTGGATAAAGGTATCACGCCATTGGATCGGCTATCGCTGCACATTTGCCACGCCTGCATCAGCTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCGCAGACGAAGCAGCGACAATGGCTGGAGACGGACAAGAGCAAGCAGCAGACGCTACTCGGCTATTTGGATTTGAATAAGACGGAGAACGGCAGCACCGCggaccatcagcagcagcagcaacaccacgAATTGAAAAACGATTTGGCGACAACTGCAGCTGAAAAGGCGTCCGCCAACATTTTGGATGGCATACCCTCGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCaaagcaacagctacaacagcaacaacaacatcaacagcagcagcagcagcaacaactacagcagcagcagcagcaaccgcataCAGCAAGATCGACGAGCGCGGCGGCGGATTCACAGCAATCATTGCAGACCCTTTTATTGCAGGTGCCCTCAGCAACAttggcaacgacaacagcagcatcagcagcagcatcatcacagcagcagcgcaagcaacaccaacagcagcaacgtgGCAGGCAGCAACACCATCAACAGCTACATCAgccacatcagcaacaacaacaacaacaacaacaacaacaacttcatcCACAGCAGCGTCTGAGTCGCATTCGTCAGCCGCGACGCCACCAGCAGGCGCTGTCCGCGCAGCGTTTGGCCAAATTTAGGCCCAAATTATATTTGCCATTGGATATATCGGTGccatcgctgccgctgccgctgccactgccgctgcctctgccgccgccgccaccgccagtGTTGTCAACTGTTGCTAGTGCTGGTGCTGAGCTGgcgccgttgtcgttgccacTCGATTTCGGCCAGAATCAGTGTCAGAATCAAAATCTGAATCAGAGTCAGAAACTTGGCGGCattttgccgctgccgccgccgacgccgccgcatCCGCCGCCAGTTGCAACaatgagcagcaacaacgctGCCGTTGGCTCTGCCGCAGTCACGACTCCGCTGCTCATGCCGCCGCTGCCTGCTGTGCCCATCAAGGATGAGCCCCTGGATGATACGGACGATGACTTTCAAATGAAGTGCATAGACGAGTCCGATGACATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCACTAATGACCTCCGACTATGATTACACGGCGCAGCACGGCGTgacggcggtggcggcggcggcaacgctGCCCGCCAGCGCTGTGGCGAATGTGGCCGCCGCCGGGGACTCCAAGGTGGCCAGCTGCCGGGCGTGCAGTCTGCAGTTTTCGACGCGGGCGAATGCGCGACGCCACGAGCGCAATCTGCATCCAAATCTGTTCCAATTGTCGACAGACTCGCCAAATAATACGCCAATCACAAAACCGACGCCGGCACTGGCCGCCGCTTTGGAGATACAGCGGGCAGCTGCCGCGGCCGCTGCCACCGCGGAGGCAACAAAggccgccgccggcggcaaCATATCAGCGCAAAAATATCGCCAGGTGGTGATGAACACGTTCATCAAGTGCGAGAACGGCGGCTACGACTACGACAGTCCCGAGCAGtaccagcagctgctcacCCGCGACAAGGTGGAGTTCATTCAGGAGAACAACGAGTTCCTCGAACAGTACCAAACGATGACGTGTCGCTGctgcaacaaatatttcaacaccTACAAGAACTTTATGGCGCACGTACGCAAAAAGTATCCGCTGCTGCCGCGCAATCTGTGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATATCGCATCTAAAGAAGCGCAACTGCATCAACTTGTATCGTGTTCTAAACGCTTTGCGCATCAAGCAGCCAAACTTTTCCCATGCCAATGCATCTGGCCTGGCTGTCACAGCGGAcggacagcaacagctgcagcagcatcatcaacagcagcagcagctgattgcTGGCGGCGAAACGTCAACGGAACGGCCGGAAAAGCTGCGCGCCAAGGAGCTGCTGGTGAACAAATTGTACGAGTGCAAACTCTGTCCGAAGGGCTTTCGCACCAAGCACGAGTTTCGCACCCATGTCTATGACAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGTCTGGACTTTGCCGATCCGGTGGATCGACGTCGCCACTACAACAACATGGACTGCATTGTCCGGCTGCGCTGCATGACCTGCGATGCCAAATTGGAGACGCACCAGCGCTTCTTGGATCACGTCTACCAGGATCATTTGGGCGGCGTTGGCAGCGACAATGCATCCACAGCGAACAGCGGCGGACTCGATCATTCGCCCGGCAAACGGAGCCTGCTGGGCGCCCTCGGCATCGGTGTCAGTCAGTCCTCGAATGAGGAGTCGCGCAGCAGCGGccatcacaacaacaatgctgcGTCTGAGGCGCCGCTCACCTCGACACCGAAACCAGccggaggagcagcagcagcagcagcagcggcagcaacgggtgcagcagcagcgaccagCGGCGGTTCCACATCGGGCAATCGTGATGCGCCCAAGTCGCAGTATTTTTCGCGCATGCCGCAGGTTTGCCCGATCTGTGGACAACagtacaacaactacaataacgTGCTGCGCCACATGGAATCGAAGCATCCCAATAAACTGCCAGAGACGTACAAGTGTGTCCGGTGCGGATTGGGCTATCCGCGAATCTCGTACCTGCGCGAGCACATGATCAATGTCCATGGCGTGGACAAGAATCGCCACTCGGGCGGCTTTGAGTATATTGTCAATGCCGATGCGGTTAAGTTGGCCGATGGCAGCACGCCAAATGTTTATACCGGACGCTACGACTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgATGACGATGAGGAGGAGGGCGGCAGCATTGCCAAGAAGATGCGACTggacgacagcagcaacaacagcagcagcatcaacatgAGCCTGGCCAACCAACAGAAGGAGTGCCTCATCTGCAATGCGGTgttcagcaacaacattggcCTCTCCAATCACATGCGATCCCATTACACCGCATCAACGGCGACGAGCGCCGCTTTGGCGGCGGCCAATCGGATGACGCCCAAATCGCTGACAATTACCGCAACGCCGCCGCTGGAAACGGCTGTTGTGTCGTCCACGGCGTCAGCAcctgccacaacaacagcagcagcagcagcaacagttgtagcaacaactgcagtagctgctgcaacaacagcaacaacagcagccgcagcagcagcagctggaggcaGCTTGCCGCCAGCGATGGCAAATCAAACGCCACAGGAGCAGGCGGTATTCCGGCGTAGTCTCGATCAGGCGGCCGATCGTCGTTTCCGGCGGATGCGTTGCCGCATCTGCCAGCGCAGATTCAGCTCGAAGAAATCGTACCGCTACCACATGCTGACCGATCATCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCGGAGTTTGCCTACGAGAAGGGTCTCAAGGTGCATCTGTTCAAGGTGCACGGACGCGCCATCAAGGACGAGATGATTGTCAAGCAGTTCGAGTGTGATATCTGCTCCATTGTCTACAGCAACGAactggagctgcagcagcacaagcGCAGCGTTCACAAATCCCATTCCGGATCGGATTCCAACAAGTCGATGAAATCAGCTACGGCTACCGCTACCGCTACCTCAGCCGAACTGGCCGAGACATCCGGCacggctgcaacaacaacattgcccCTCTATTGGTACCAGTGCAAGTACTGTCCATCCAATTTcaataccaacaaaaaactggCCATACACATCAACTCGCACGACGAGTTCGACTCCAACGACTACTCCTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGCCTCTGGGTGCATCGCTATAAGAAGCATCCTCAGGTGCCCGATCCCGCTGAGTGCACGTTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCACACGCCCACCTGCAATCGCAAGCCCATCACTGCCACCGGCGCCCATCAGCAagatcagcaacagcagcagcagcagcaacaacagcagcagcaacagctgcatcagcatcagcgtgGCATCTTCAAGCACAAAACaggcgatgatgatgaggaggaggatgatgatcagctgctgctgctggacgatGGCGTCGGCGGCGATAGCAATGGTGGCAATGCCATTGGTGGATCAACTGGCAATCCGAGCACGATCAGCACGAGCACACTGAAGATTAGGATACCGGAGGTGGCGTGCACCATTTGCGGTGCTCGATTCACCGATCAGGAGATGTTCACCAAGCACATACAGAAGCACGAACAGGATCTCTATGTGGACAACCCGTTGGCGGCCATGTTCGATGATGGACCAGCCGATGCTGGCCAGTTTCAGGTGGAGCGTCAAAACGAGAACGGCGAATACGCGTGCGATCTGTGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCAATCATCGACGGCGAAGCGACAACgctgaacaacagcagcagcaacaacaacaacaacaacaattcaatgCTGCATCTGCGCGAACTGCATGCGGTGGGTCTGATGCCCaaccagcagcaccagaagcagcaacagctgcagctgcaacagcagcagcagcagcagcaacatcagcggaACAACACGTCGAGCAGTTCGAGCAAATCGCTGAAACGGAAACGTGAACTGAAATGCGACTACTGCGCCTCCACattcatcagcaacaacaatctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCCACCTCCCGGAGCCGCCAGTGATTGAGGTGGACGAGCCGCTCACGTGTCGCCGTTGCGGTGATCTTCAGTTCGAGACAAAAGAGCTGTGGATCGAGCATAAGCTGGCCGATGCGAAGGTGGTCCGTCCGTTCTGTCCGTTTCAATGGGGCTGCGATCTGTGCGGCGAGTATTTGTCGCGCAAGGAGAAGCTCATCAATCACATCAACAATCATCTCAAGGAGGATGTGATTGTCCCCGTTGCAGTGGccgttgccaaaaataaaaatacagcaaaaacatcaacaacagcagcagcaacaacagcagcagcagcagcaacaacagcagttgctgatgcagcaacgacaacaccAGCCATAAAGGCAACAATCAAAACGAAggccaaacagcagcaggaagagGATGCGGAGGCGGAGACGGAGGCGCAGGTGGaactcaaattaaatgctGGCAAGCTGGCGAAGCAGGCGGATGATAGTGATATGGATGATAGCGATAGTGGCGATGATGAGGATAGCACAAGTGctggcgatgatgatgacgatgatgatgacgacgacgatgaggaCGGGGAGgtcgatgatgacgatgatgacgacgacgatgatgatgatgatgacgaagacgaagatgttgtgcagcaacagcagctgctgcagcagaaacaacaacagcagcagcagcaaccgctcaacagcaacaacaataataataacaacaacaacaacaacacaagtgTTGTGGCCAACGATGATATCGATGATCTCATTGAGGAGGTGATCGAGGTTGATGGCATGGTCGAGGAACTGAACGATGATGAGgaggacgacgatgacgatgacgacgacgatgtgGATGATGACGATGTGGATGAAGTCGATGAGGACGATGGCAACACCACAGATGAGCAccagcagctgaagcaggcGGAGCAGCGGGAACAGCATCAGCCGCGGCGACTCAACTTTGACTACAGCCGGACGGATAGCGCCAAGCTGAATGGCACCGGTGGTAAACAGACGCTGGCAAAGTCGAAGCCGGTGTTGGTCATGCACAGctccgaggaggaggaggaggaggaggaggacgatgATGTCGATGATGGTGTggatgatgaggatgaggatgcgGGCGGTGTTGGTGAGGCAATGACCATCGATGATATTATTGAAGAGGACGATGatgcagatgcagatggtggcacatcatcatcatcatcatcatcatcatccgaGAGCGAgtcgacagcaacaacatcgcaGTCAATTGgagctgctgcagtcACATATTAA
Protein Sequence: MNARIALAIGKENSNYRWLDKGITPLDRLSLHICHACISYLNSWQSFKNRCLSSQTKQRQWLETDKSKQQTLLGYLDLNKTENGSTADHQQQQQHHELKNDLATTAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQHQQQQQQQQLQQQQQQPHTARSTSAAADSQQSLQTLLLQVPSATLATTTAASAAASSQQQRKQHQQQQRGRQQHHQQLHQPHQQQQQQQQQQQLHPQQRLSRIRQPRRHQQALSAQRLAKFRPKLYLPLDISVPSLPLPLPLPLPLPPPPPPVLSTVASAGAELAPLSLPLDFGQNQCQNQNLNQSQKLGGILPLPPPTPPHPPPVATMSSNNAAVGSAAVTTPLLMPPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVAAAATLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGYDYDSPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRIKQPNFSHANASGLAVTADGQQQLQQHHQQQQQLIAGGETSTERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGSDNASTANSGGLDHSPGKRSLLGALGIGVSQSSNEESRSSGHHNNNAASEAPLTSTPKPAGGAAAAAAAAATGAAAATSGGSTSGNRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEEGGSIAKKMRLDDSSNNSSSINMSLANQQKECLICNAVFSNNIGLSNHMRSHYTASTATSAALAAANRMTPKSLTITATPPLETAVVSSTASAPATTTAAAAATVVATTAVAAATTATTAAAAAAAGGSLPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSIVYSNELELQQHKRSVHKSHSGSDSNKSMKSATATATATSAELAETSGTAATTTLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQQQQQQQLHQHQRGIFKHKTGDDDEEEDDDQLLLLDDGVGGDSNGGNAIGGSTGNPSTISTSTLKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTLNNSSSNNNNNNNSMLHLRELHAVGLMPNQQHQKQQQLQLQQQQQQQQHQRNNTSSSSSKSLKRKRELKCDYCASTFISNNNLRRHMYELHKHEVSHLPEPPVIEVDEPLTCRRCGDLQFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVAVAVAKNKNTAKTSTTAAATTAAAAATTAVADAATTTPAIKATIKTKAKQQQEEDAEAETEAQVELKLNAGKLAKQADDSDMDDSDSGDDEDSTSAGDDDDDDDDDDDEDGEVDDDDDDDDDDDDDDEDEDVVQQQQLLQQKQQQQQQQPLNSNNNNNNNNNNNTSVVANDDIDDLIEEVIEVDGMVEELNDDEEDDDDDDDDDVDDDDVDEVDEDDGNTTDEHQQLKQAEQREQHQPRRLNFDYSRTDSAKLNGTGGKQTLAKSKPVLVMHSSEEEEEEEEDDDVDDGVDDEDEDAGGVGEAMTIDDIIEEDDDADADGGTSSSSSSSSSESESTATTSQSIGAAAVTY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00506259; iTF_00567675;
90% Identity: -
80% Identity: -