Basic Information

Insect: Drosophila ezoana
Gene Symbol: hang
Assembly: GCA_035045725.1
Location: JAWNOU010000044.1:8931834-8943383[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.38 27 5.6 1.0 3 23 444 465 443 465 0.93

2 18 1.1 79 4.2 3.2 3 22 572 591 570 591 0.89

3 18 0.00083 0.059 14.0 3.3 1 22 686 707 686 709 0.90

4 18 0.095 6.8 7.5 0.1 2 21 721 740 720 741 0.93

5 18 0.00096 0.068 13.8 0.2 2 23 867 889 866 889 0.95

6 18 0.0028 0.2 12.4 0.1 1 23 897 920 897 920 0.96

7 18 0.00021 0.015 15.9 0.2 2 23 1006 1027 1005 1027 0.97

8 18 0.0004 0.028 15.0 2.9 2 23 1148 1170 1147 1170 0.97

9 18 0.031 2.2 9.1 0.2 2 23 1179 1201 1178 1201 0.95

10 18 0.0017 0.12 13.1 0.1 1 23 1214 1237 1214 1237 0.97

11 18 0.00017 0.012 16.2 1.1 1 23 1278 1300 1278 1300 0.99

12 18 0.0027 0.19 12.4 0.9 1 23 1308 1331 1308 1331 0.96

13 18 0.094 6.7 7.6 0.4 2 19 1339 1356 1339 1357 0.94

14 18 9.9e-05 0.0071 16.9 0.4 3 23 1459 1479 1458 1479 0.98

15 18 0.007 0.49 11.1 0.1 1 23 1514 1536 1514 1536 0.97

16 18 0.00082 0.058 14.0 0.6 2 23 1619 1641 1618 1641 0.93

17 18 0.0088 0.63 10.8 0.3 3 23 1697 1717 1697 1717 0.98

18 18 9.7e-05 0.0069 16.9 2.0 1 23 2177 2199 2177 2199 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.38	27	5.6	1.0	3	23	444	465	443	465	0.93
2	18	1.1	79	4.2	3.2	3	22	572	591	570	591	0.89
3	18	0.00083	0.059	14.0	3.3	1	22	686	707	686	709	0.90
4	18	0.095	6.8	7.5	0.1	2	21	721	740	720	741	0.93
5	18	0.00096	0.068	13.8	0.2	2	23	867	889	866	889	0.95
6	18	0.0028	0.2	12.4	0.1	1	23	897	920	897	920	0.96
7	18	0.00021	0.015	15.9	0.2	2	23	1006	1027	1005	1027	0.97
8	18	0.0004	0.028	15.0	2.9	2	23	1148	1170	1147	1170	0.97
9	18	0.031	2.2	9.1	0.2	2	23	1179	1201	1178	1201	0.95
10	18	0.0017	0.12	13.1	0.1	1	23	1214	1237	1214	1237	0.97
11	18	0.00017	0.012	16.2	1.1	1	23	1278	1300	1278	1300	0.99
12	18	0.0027	0.19	12.4	0.9	1	23	1308	1331	1308	1331	0.96
13	18	0.094	6.7	7.6	0.4	2	19	1339	1356	1339	1357	0.94
14	18	9.9e-05	0.0071	16.9	0.4	3	23	1459	1479	1458	1479	0.98
15	18	0.007	0.49	11.1	0.1	1	23	1514	1536	1514	1536	0.97
16	18	0.00082	0.058	14.0	0.6	2	23	1619	1641	1618	1641	0.93
17	18	0.0088	0.63	10.8	0.3	3	23	1697	1717	1697	1717	0.98
18	18	9.7e-05	0.0069	16.9	2.0	1	23	2177	2199	2177	2199	0.99

Sequence Information

Coding Sequence: ATGTTGCTGTGCGGGTGCCTTGACTGGCTGAGTATGGGGAATAAGATCACGCCTTTGGATCGTCTATCGCTGCATATTTGCCATGCCTGCATCAGCTATTTGAACTCTTGGCAGAGCTTTAAGAATCGCTGCCTCAGCTCACAGTCCAAGCAGCGGCAATGGCTGGACACCGATAAAAGCAAGCAGCAGACACTTTTAGGATATTTGGATTTGAACAAAACGGAGAATGGCAGCTCCATTGAACAGCAGCACGAAACGAACATCGATTCGgcgacagctgcagctgaaaagGCGTCCGCCAACATATTGGATGGCATACCCTCGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCaaagcaacagctacaacagcaacaacagctacaacagcagcaacaacaacaacaacaacagcagcagcaacagaatgCTGCAAGAACGACGAGCGCGGCGGCGGAGTCACAGCAAACACTGCAGACCCTTTTATTGCAGGTGCCCTCAGCAACATTGACAACGGCGTCAactcagcaacagcaacaacagcgaaaatatcaacagcagcagcaacgtggCAGGCAGCAACATtaccaccagcaacaacagccgcaacaacagacgcaacaacaacaccaacagcatcatcagcagcagcagcgacttaGTCGAATACGTCAACCACGACGCCAGCAACAGACGACAACGTCTGCCCAGCGTTTGGCTAGGTTCAAGCCCAAATTGTATTTACCATTGGATATATCAGTGCCGCCGCTTCCGccgttgttgccgccgccgttgccgcccATGTTGTCAACTATTATTGGTGGTGCTGATTTGGCGCCGTTGCCAGTGCCGTTGTCGATGCCACTTGATTTCAGCCAGAGTCAGTGTCCGAATCCGAAAGCGAATCAGAGTCACAAACATAGCAGCGTgttgccgccaccgccgccaccgccgccgccgctacCGCTGGCTCCAGTTGTAACAATGACCAGCAacgcctctgcctctgccactggctctgccgcagccgcagtaACGACTCCATTGCTCATGCCGCCGCTGCCTGCCGTGCCCATCAAGGATGAGCCCATTGACGACACGGATGATGACTTTCAAATGAAGTGCATAGACGAATCCGATGACATGATGGATCCAACAATGTTCCTAGAGCGCTCCGAGCATGAGGGCGATGTGCCACTAATGACCTCCGACTATGATTACACGGCGCAGCATGGCGTGACGGCGGTTGTGGCGGCGGCATCGCTGCCCGCCAGCGCGGTTGCGAATGTGGCCGCCGCTGGCGACTCCAAGGTGGCCAGCTGCCGTGCCTGCAGTCTGCAGTTCTCGACGCGCGCGAATGCGCGACGCCACGAGCGCAATCTCCATCCGAATCTGTTTCAACTGTCGACAGACTCGCCAAATAATACGCCCATCACAAAACCGACGCCGGCATTGGCAGCCGCGCTGGAGATACAGCGTGCAGCTGCCGCGGCAGCGGCCACCGCGGAGGCAACTAAAGCTGCCGCCGGTGGCAACATATCAGCGCAAAAGTATCGCCAGGTGGTCATGAACACGTTCATCAAGTGCGAGAACGGCGGCTTCGACTACGACAATCCAGAACAGTATCAGCAGCTGCTCACCCGCGACAAGGTTGAGTTCATTCAAGAGAACAACGAGTTTCTGGAGCAGTACCAGACGATGacctgccgctgctgcaacaAATACTTTAACACATACAAGAACTTTATGGCGCATGTACGCAAAAAGTATCCGCTGCTGCCGCGCAATTTGTGCTTCAATTGCCTCAAGATGAACGACTCCAAGGCACTGTTCATATCGCATCTGAAGAAACGCAATTGCATCAATTTGTATCGCGTTCTCAACGCTCTACGCATCAAGCAGCCAAACTTCTCTCATGCCAACGCATCCGGAGCGGCTGTTTCAACTGATATGAGTGGTGTTccaggtgctgctgctgcaggacaCGAAACATCAATGGAACGGCCAGAGAAGCTACGCGCCAAGGAGCTGCTGGTGAATAAACTGTATGAGTGCAAGCTCTGCCCAAAGGGCTTTCGCACCAAGCACGAGTTCCGCACCCATGTGTACGACAAGCATGCGGATGTACAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGACTGGACTTTGCCGATCCGGTTGATCGCCGCCGTCACTACAACAACATGGACTGCATTGTGCGGCTACGCTGCATGACCTGCGATGCCAAGCTGGAGACGCATCAGCGCTTCCTCGACCATGTCTATCAGGATCATTTGGGCGGCGTCAGCAGCGACAATGCGTCCACCGCGAACAGCGGCATGGATCATTCGCCGGGCAAGCGTAGCCTGCTGGGCGCCCTTGGCATTGGTGTCAGTCAGTCATCCAATGATGAgtcgcgcagcagcagccacaacaacaacaatgccgtGGAAACGCCGCTCACCTCAACACCGAAACCGGCTGCATCGGGAactgcagctgcggcggcgACCAGTGGCGGCTCCACATCTGGCAATCGCGATGCCCCCAAATCGCAGTATTTTTCCCGCATGCCGCAGGTGTGCCCCATTTGTGGCCAGCagtacaacaactacaacaacgtGCTGCGCCACATGGAGTCAAAGCATCCCAATAAACTGCCCGAGACGTACAAATGTGTACGCTGCGGCCTTGGCTATCCGCGAATCTCATATCTGCGCGAGCACATGATTAATGTGCATGGCGTGGACAAGAATCGGCATTCCGGAGGCTTTGAATATATTGTGAATGCCGATGCCGTTAAATTGGCGGACGGCAGCACGCCCAATGTCTATACCGGACGCTATGATTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTCgatgatgaggaggaggagagcGGAAGCGTTGCCAAAAAGATTCGCCTCgatgacagcagcaacaacagcagcatcaacatgAGCATCGCCAATCAGCAAAAGGAATGCCTCATCTGCAATGCGGTGTTCAGCAACAACATTGGGCTATCCAATCACATGCGCTCGCATTATACCGCCTCCACGACGACGAGCGCAGCGCTGGCGGCGGCCAATCGCATGACGCCAAAGTCGCTGACAATTACCGCAACGCCGCCACTGGAAACGGCTGCCGCATCGTCCACCGCAAGCATTGTGGTgtcagcggcggcggcggcggcaacagcagcagcagcagcagcaacgcccGCCACaagcacagctgcagcagctgcgagtgcaactacaacaacaagtacaacagctgccgccgccgctgctgcgtCCGCGCCCGGCAGTTTGCCGCCAGCGATGGCACATCAAACGCCACAAGAGCAGGCAGTATTCAGACGTAGCCTGGATCAGGCAGCCGATCGTCGCTTTCGGCGCATGCGCTGTCGCATCTGCCAGCGCAGATTTAGCTCAAAGAAATCGTACCGCTACCACATGCTGACCGACCATCAGGTGCAGAACGTTCAGTTCATTAAGTGCAAGCTGTGCAATGCGGAGTTCGCCTACGAGAAGGGCCTCAAGGTGCATCTCTTTAAGGTGCACGGACGGGCCATTAAGGATGAGATGATTGTGAAGCAGTTCGAGTGCGATATCTGCTCCATTGTCTACAGCTctgagctggagctgcagcagcacaagcGCAGCGTGCACAAGTCCCAGCTGGGCGCCAACGACGCGGCCAAGTCAAAATCGTCAGCAGCTTCCTCAGCCTCAGCTGCTGACCTTGCCGAAACGTCCGGCACGGCTGTGCCAGCCCTGCCCCTCTACTGGTACCAGTGCAAGTACTGTCCATCCAATTTCAATACCAACAAAAAACTAGCCATACACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGTGGCCGCAAAAGTCTTTGGgTGCATCGCTATAAAAAGCATCCGCAGGTGCCGGATCCCGCTGAGTGTACGCTGTGCCGCAAGATGTTCTTTGACCGCCAGATGCTGGAGAATCACACGCCCACCTGCAATCGGAAGCCCATCACTGCCACCGGCGCCCATCAGCAGGattcgcagcagcagcaacagcatcagcatcagcagcagctgcaactgcagcagcagcgcggcaTATTCAAGCACAAAACGGGCGACGAtgacgaggaggaggatgatGATCAGCTGATGGTGCTGGACGATGGCGTCTGCGTCGGCAGTAGCAGCAACGGCGGCAAtgctgccacagctgcagcagcagctgcagcagcaggatcaGGCAATGCGAATAGCAGCACATTGAAGATACGCATTCCGGAGGTGGCATGCACCATTTGCGGTGCCCGGTTCACCGATCAGGAGATGTTCAGCAAGCATATACAGAAACATGAACAGGATCTGTATGTGGATAATCCATTGGCGGCCATGTTCGATGATGGACCAGCGGACGCTGGCCAATTTCAGGTGGAGCGCCAGAACGAGAACGGCGAATATGCGTGCGATCTGTGCGCCAAGACGTTCCCCCAGGTGATAGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGaaTCCCATCATCGACGGCGAAGCGACAACGctgaacaacagcaacaacaacaacaacaattcgctGAGCTCCTCATCGATGCTCCATCTGCGCGAACTGCATGCTGTGGGCCTGATGCCCAATCAGCAGCaccagaaacaacaacaacaacaacagcagcagcagcagcagcaacaacaacagcagcagcagcagaggaagTCGCTGAAACGGAAACGTGAACTGAAATGCGAATATTGCGCATCCACATtcattagcaacaacaacctgcGTCGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAATCTGCCGGAGCCGCCAGTGATTGAAGTGGATGAGCCTTTGACTTGTCGCCGTTGCGGCGATCTACGGTTTGATACCAAAGAGCTGTGGATCGAGCATAAATTGGCCGATGCCAAAGTTGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAGTACCTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAAGAGGATGTAATTGTGCCCGTGGCAGTGGCGGTGTCCACCAAGCCAGCGTCAACAGTTCCCAGCAagaatgcaacaacaaaatctccagcaacaacagcaacagcagcggcgtcAGCAACAGGAGGCACAAAGGGCATAATAAGAGCGGGAGGAGCAGTAAGAGtgcttaaaaacaaacaattggATGAGCTGCAGGAGCAGCTAGACATGAAAGTAGCGAAGCTCTCCAAACAGCATGTGGCGCACGATGATGAGGAGGAAGCGGGGCAGGAGCAGCGGGAACAGGTGGAGGCGGATGATAGTGATATGGATGATGATAGCGATAGTGGCGAGGATGATGAGGATAGCACAAGcgctgatgatgacgacgatgatgatgatgacgatgatgatgacgacgatgaggGCGATGtggacgatgacgatgacgaagaTATTGTGgaacggcagctgctgcaacaacaacaacaacagtctctcaatagcaacaacaagaacaataataataacaacaacaacaatagcgtAGTTGCaaatgacgatgacgatgatctCATTGAGGAGGTAATCGAGGATGATGGCATTGTCGAGGAGCTAGAAGATGATGAGGACGATGACGAGGAGGACGACGATGAGGCCGATGgcgttgatgatgatgatgatgacggcGATGGTAACACATCGGATGAGCATCAGGCGCTGCCTTCCAATGCCACCAAACAGCAGCCGAGGCGCCTCAACTTTGACTACACGCGCACAGACAGCTCCAAGCTGaacggcaatggcaatggcaaacaGACGCCGCAGAAGCATCAGCAAAAGTCAAAGGGTCAGCAGGCGCAGGTGCTGGTCGTGCACAGCTCAGAGGATGAGGCGGATGATGTCGATGGGGATGCTGATGAGGATGTGGACGATgtggatgatgatgaggaggaggtggaggaggaggatggCGTGGGTGAAGCAATGACCATTGATGATATTATTGAAGAAGATGATGGGGAGGATGATGACGATGTGGTTGGTGTCGATGGTGGTGTTgttgaggatgatgatgatgatgttgacgAAGATATGGACGAGGATGATgttgacgacgacgatgacgaagacgacgacgatgatggtggtggtggtgctgctgctggtcgtCGCGCTGGCGCCGCCAggggcagcggcagtggcagcggcagcggcagtcgCATCGGCGCGTCTgatggtgtggctgctgatgCCGATGGTGGTACATCATCATCTGAGAGcgagtcaacaacaacaacaacaacatcgcaTTCAATTGGTGAGCGGCGTAAAAAAACAGTAGTTAAATCAGCGGCACATGGCGCTGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGTTACTGCAGTCACATATTAAAAGCCATTTTCTGAATGGCCCGTCGTCGGCGGGCAGCGTcagcgccagcggcagcggcagcaacagagGCGTCAGcctcggcggcggcagcggcagcggcagcgctagcggcagcagaagcaacaataataataataacatcgacagcagcaacagcggcaacggcaacggcagcggcagcagcagcaacagcaacaacaaaaccaaaaccaaaaagtcCGGCTTGGATGCAATCAAAAGTGGCAGTGCTGCAACAAcgtcgacagcaacaacaacaacaacaacagcaaaagttacagctgaagcagctgcaacaacagcagcagcggacgCTGCAACCAGCTTGAACTGA
Protein Sequence: MLLCGCLDWLSMGNKITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLDTDKSKQQTLLGYLDLNKTENGSSIEQQHETNIDSATAAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQLQQQQQQQQQQQQQQNAARTTSAAAESQQTLQTLLLQVPSATLTTASTQQQQQQRKYQQQQQRGRQQHYHQQQQPQQQTQQQHQQHHQQQQRLSRIRQPRRQQQTTTSAQRLARFKPKLYLPLDISVPPLPPLLPPPLPPMLSTIIGGADLAPLPVPLSMPLDFSQSQCPNPKANQSHKHSSVLPPPPPPPPPLPLAPVVTMTSNASASATGSAAAAVTTPLLMPPLPAVPIKDEPIDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRIKQPNFSHANASGAAVSTDMSGVPGAAAAGHETSMERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGVSQSSNDESRSSSHNNNNAVETPLTSTPKPAASGTAAAAATSGGSTSGNRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDEEEESGSVAKKIRLDDSSNNSSINMSIANQQKECLICNAVFSNNIGLSNHMRSHYTASTTTSAALAAANRMTPKSLTITATPPLETAAASSTASIVVSAAAAAATAAAAAATPATSTAAAAASATTTTSTTAAAAAAASAPGSLPPAMAHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSIVYSSELELQQHKRSVHKSQLGANDAAKSKSSAASSASAADLAETSGTAVPALPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDSQQQQQHQHQQQLQLQQQRGIFKHKTGDDDEEEDDDQLMVLDDGVCVGSSSNGGNAATAAAAAAAAGSGNANSSTLKIRIPEVACTICGARFTDQEMFSKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTLNNSNNNNNNSLSSSSMLHLRELHAVGLMPNQQHQKQQQQQQQQQQQQQQQQQQQRKSLKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDLRFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVAVAVSTKPASTVPSKNATTKSPATTATAAASATGGTKGIIRAGGAVRVLKNKQLDELQEQLDMKVAKLSKQHVAHDDEEEAGQEQREQVEADDSDMDDDSDSGEDDEDSTSADDDDDDDDDDDDDDDEGDVDDDDDEDIVERQLLQQQQQQSLNSNNKNNNNNNNNNSVVANDDDDDLIEEVIEDDGIVEELEDDEDDDEEDDDEADGVDDDDDDGDGNTSDEHQALPSNATKQQPRRLNFDYTRTDSSKLNGNGNGKQTPQKHQQKSKGQQAQVLVVHSSEDEADDVDGDADEDVDDVDDDEEEVEEEDGVGEAMTIDDIIEEDDGEDDDDVVGVDGGVVEDDDDDVDEDMDEDDVDDDDDEDDDDDGGGGAAAGRRAGAARGSGSGSGSGSRIGASDGVAADADGGTSSSESESTTTTTTSHSIGERRKKTVVKSAAHGAAADQSNSSYTCDLCQLCFDSQELLQSHIKSHFLNGPSSAGSVSASGSGSNRGVSLGGGSGSGSASGSRSNNNNNNIDSSNSGNGNGSGSSSNSNNKTKTKKSGLDAIKSGSAATTSTATTTTTTAKVTAEAAATTAAADAATSLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00561176;
90% Identity: iTF_00526720;
80% Identity: -