Basic Information

Insect: Drosophila paramelanica
Gene Symbol: hang_1
Assembly: GCA_035043915.1
Location: JAWNMO010000562.1:395211-412257[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.38 23 5.6 1.0 3 23 523 544 522 544 0.93

2 18 1.1 68 4.1 3.2 3 22 651 670 649 670 0.89

3 18 0.00081 0.05 14.0 3.3 1 22 772 793 772 795 0.90

4 18 0.094 5.8 7.5 0.1 2 21 807 826 806 827 0.93

5 18 0.00094 0.058 13.8 0.2 2 23 964 986 963 986 0.95

6 18 0.0027 0.17 12.3 0.1 1 23 994 1017 994 1017 0.96

7 18 0.00021 0.013 15.8 0.2 2 23 1103 1124 1102 1124 0.97

8 18 0.00039 0.024 15.0 2.9 2 23 1232 1254 1231 1254 0.97

9 18 0.031 1.9 9.0 0.2 2 23 1263 1285 1262 1285 0.95

10 18 0.0012 0.075 13.4 0.2 1 23 1298 1321 1298 1321 0.97

11 18 0.00017 0.011 16.1 1.1 1 23 1364 1386 1364 1386 0.99

12 18 0.0026 0.16 12.4 0.9 1 23 1394 1417 1394 1417 0.96

13 18 0.073 4.5 7.8 0.4 2 19 1425 1442 1425 1443 0.95

14 18 3.6e-05 0.0022 18.2 0.4 3 23 1533 1553 1532 1553 0.98

15 18 0.0068 0.42 11.1 0.1 1 23 1588 1610 1588 1610 0.97

16 18 0.00082 0.051 14.0 0.7 2 23 1698 1720 1697 1720 0.93

17 18 0.0087 0.54 10.7 0.3 3 23 1776 1796 1776 1796 0.98

18 18 9.6e-05 0.0059 16.9 2.0 1 23 2249 2271 2249 2271 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.38	23	5.6	1.0	3	23	523	544	522	544	0.93
2	18	1.1	68	4.1	3.2	3	22	651	670	649	670	0.89
3	18	0.00081	0.05	14.0	3.3	1	22	772	793	772	795	0.90
4	18	0.094	5.8	7.5	0.1	2	21	807	826	806	827	0.93
5	18	0.00094	0.058	13.8	0.2	2	23	964	986	963	986	0.95
6	18	0.0027	0.17	12.3	0.1	1	23	994	1017	994	1017	0.96
7	18	0.00021	0.013	15.8	0.2	2	23	1103	1124	1102	1124	0.97
8	18	0.00039	0.024	15.0	2.9	2	23	1232	1254	1231	1254	0.97
9	18	0.031	1.9	9.0	0.2	2	23	1263	1285	1262	1285	0.95
10	18	0.0012	0.075	13.4	0.2	1	23	1298	1321	1298	1321	0.97
11	18	0.00017	0.011	16.1	1.1	1	23	1364	1386	1364	1386	0.99
12	18	0.0026	0.16	12.4	0.9	1	23	1394	1417	1394	1417	0.96
13	18	0.073	4.5	7.8	0.4	2	19	1425	1442	1425	1443	0.95
14	18	3.6e-05	0.0022	18.2	0.4	3	23	1533	1553	1532	1553	0.98
15	18	0.0068	0.42	11.1	0.1	1	23	1588	1610	1588	1610	0.97
16	18	0.00082	0.051	14.0	0.7	2	23	1698	1720	1697	1720	0.93
17	18	0.0087	0.54	10.7	0.3	3	23	1776	1796	1776	1796	0.98
18	18	9.6e-05	0.0059	16.9	2.0	1	23	2249	2271	2249	2271	0.99

Sequence Information

Coding Sequence: ATGTGCGACACTGTCGTtacaacagtagcagcaggcACTGGAACGGTCACAGCCACTGGAAcgggaacaggaacaggagctGCTGGCGCGGCGGATActgcagcgacaacgacagcaatGGAGGAGCGTATGCGAAAAAGTTGCTGTCGCTTGTGCATTGCACCCGCCAGCGAATGCATTTCGATTATTAACAGTTATGCGGCCGATAAGGAGCCGCTGgccacaaaaatacacaactgCGTAAATATCAAGATCACGCCATTGGATCGGCTATCTCTGCACATTTGCCACGCCTGCATCAGTTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCGCAGACGAAGCAGCGACAATGGCTGGAGACAGACAAGAGCAAGCAACAGACGCTACTCGGCTATTTGGACTTGAATAAGACGGAGAACGGCAGCTCCACGgaccatcagcagcaacatcacgAATTGAAAAACGATTCGgcgacagctgcagctgaaaagGCGTCCGCCAACATTTTGGATGGCATACCCTCGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCaaagcaacagctacaacagcaacaacaacaacaacatcaacagcaacagcagcagcaacaactacagcagcagcagcagcagctaccgCATGCAGCAAGATCGACGAGCGCGGCGGCGGATTCACAGCAATCATTGCAGACCCTTTTATTGCAGGTGCCCTCAGCAACAttggcaacgacaacagcagcagcatcatcactgcagcagcagcagcagcgcaagcaacaccaacagcagcaacgtggCAGGCAGCaacaccatcagcagcaacagcagctacatcAGCCAtatcagcaacatcaacaacagcaaccacaacaacaacaacatcatccaCAGCAGCGTCTCAGTCGCATTCGTCAGCcgcgacgccagcagcaggcgctgtCTTCGCAGCGTTTGTCCAAATTTAGGCCCAAATTGTATATGCCATTGGATATATCGGTGCCAGCGGTGCCGCTGCCTTTGCCtctgccaccgccgccgccgccagtgTTGTCAAATGTTGCTAGTGCTGGTGCTGAGCTGgcgccgttgtcgttgccacTCGATTTCGGGCAAAATCAGGGTCAGAATCAAAATCTGAATCAGAGTCAGAAAGTTGGCGGCATTTTGCCGctaccgctgccgctgccgccgccgcatccGCCGCCAGTTGCAACAATGAGCAGTAACAACGCTGCCGTTGGCTCTGCCGCAGTCACGACTCCGCTGCTCATGCCGCCGCTGCCTGCTGTGCCCATCAAGGATGAGCCCCTGGATGATACGGACGATGACTTTCAAATGAAGTGCATAGACGAGTCCGACGACATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAGGGCGATGTGCCACTAATGACCTCCGACTATGATTACACGGCGCAGCACGGCGTgacggcggtggcggcggcggcaacgctGCCCGCCAGCGCTGTGGCGAATGTGGCCGCCGCCGGGGACTCCAAGGTGGCCAGCTGCCGAGCGTGCAGTCTGCAGTTTTCGACGCGGGCAAATGCGCGACGCCACGAGCGCAATCTGCATCCAAATCTGTTCCAATTGTCGACAGACTCGCCAAATAATACGCCGATCACAAAACCGACGCCGGCACTGGCCGCCGCACTGGAAATACAGCGGGCAGCTGCCGCGGCGGCTGCCACCGCGGAGGCAACAAAGGCCGCCGCCGGCGGCAACATATCAGCGCAAAAATATCGCCAGGTGGTGATGAACACGTTCATCAAGTGCGAGAACGGCGGCTACGACTACGACAGTCCCGAGCAGtaccagcagctgctcaccCGCGACAAGGTGGAGTTCATTCAGGAGAACAACGAGTTTCTCGAACAGTACCAAACGATGACGTGTCGCTGctgcaacaaatatttcaacaccTACAAGAACTTTATGGCCCACGTACGCAAAAAGTATCCGCTGCTGCCGCGCAATCTGTGCTTCAACTGCCTCAAGATGAACGACTCCAAGGCGCTGTTCATATCGCATCTAAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTAAACGCATTGCGCATCAAGCAGCCAAACTTTTCACATGCCAATGCATCTGGCCTGACTGTGACAGCCgacggacagcagcagctgcagcagcatcaacagcagcaacagcagatgATTGTCGGCGGTGAAGCGTCCACCGAACGGCCGGAAAAACTGCGCGCCAAGGAGCTGCTGGTTAACAAACTGTACGAGTGCAAACTGTGCCCGAAGGGCTTTCGCACCAAGCACGAGTTTCGCACCCATGTCTATGACAAGCATGCGGATGTGCAGCGCAAGGACAACAATTCGATACAGTGCAGCTTCTGTGGTCTGGACTTTGCCGATCCGGTGGATCGGCGTCGCCATTACAACAACATGGACTGCATTGTCCGGCTGCGCTGCATGACCTGCGATGCCAAATTGGAGACGCATCAGCGCTTCCTCGATCATGTCTATCAGGATCATTTGGGCGGCGTTGGCAGCGACAATGCATCCACAGCGAACAGCGGCGGACTCGATCATTCGCCCGGCAAACGCAGCCTGCTGGGCGCCCTCGGCATCGGTGTCAGTCAGTCCTCCAATGAGGAGTCGCGCAGCAGCGGCcatcacaacaacaatgcgtcCGAGGCGCCGCTCACCTCGACACCGAAACTAACTGCAGCTGGACTCggaggaacagcagcagcaacagcagcaacgggtgcagcagcagcaactagcGGCGGTTCCACATCGGGCAATCGTGATGCGCCCAAATCGCAGTATTTTTCGCGTATGCCGCAAGTTTGCCCGATCTGTGGACAACAGtacaacaactataacaatGTGCTGCGGCACATGGAATCGAAGCATCCCAACAAACTGCCAGAGACGTACAAGTGTGTCCGGTGCGGATTGGGCTATCCGCGAATCTCGTACCTGCGCGAGCACATGATCAATGTCCATGGCGTGGACAAGAATCGTCACTCGGGCGGCTTTGAATATATTGTCAATGCCGATGCGGTTAAGTTGGCCGATGGCAGTACGCCAAACGTTTATACCGGACGCTACGACTACGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgATGACGATGAGGAGGAGAGCGGCAGCATTGCCAAAAAGATGCGATTggacgacagcagcaacaacagcagcataaaCATGAGCCTGGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGtgttcagcaacaacatcggCCTCTCCAATCACATGCGGTCCCATTACACAGCCTCAACGGCGACGAGTGCCGCTCTGGCGGCGGCCAATCGGATGACGCCCAAATCGCTGACAATTACCGCAACGCCGCCGCTGGAAGCGGCTGTGGTGTCGTCGACGGCATCAGCAcctgccacaacaacagcagcagctgcagttgtagcaacaactgcaacagcagcagcaacaacagcaacaacaacagcagcagcagtagcagcagctggtGGCAATTTGCCGCCCGCGATGGCAAATCAAACGCCACAGGAGCAGGCGGTATTCCGGCGCAGTCTCGATCAGGCGGCCGATCGTCGCTTCCGGCGGATGCGTTGCCGCATCTGTCAGCGCAGATTCAGCTCAAAGAAATCGTATCGGTATCACATGCTGACCGATCATCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCGGAGTTTGCCTACGAGAAGGGCCTCAAGGTGCATCTGTTCAAGGTGCACGGACGCGCCATCAAGGACGAGATGATTGTCAAGCAATTCGAGTGTGATATCTGCTCCATTGTCTACAGCAACGAACTggaactgcagcagcacaagCGCAGCGTGCACAAATCCCATTCTGGCTCGGCGGCCAGTGATTCCAACAAGTCCAATAAATCAGCTACAGCTACCGCTACCTCAGCCGAACTGGCCGAGACATCCGGGACGGCTGTAACAACGTTGCCCCTCTACTGGTACCAGTGCAAGTACTGTCCATCCAATTtcaacaccaacaaaaaactGGCCATTCACATCAACTCGCACGATGAGTTCGACTCCAACGACTACTCCTGCAAGGACTGCGGCAATGTCTACAGTGGCCGCAAGAGCCTCTGGGTGCATCGGTATAAGAAGCATCCTCAGGTGCCCGATCCCGCTGAGTGCAATCTATGCCGCAAGATGTTCTTTGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCCATCACTGCCACCGGCGCCCATCAGcaggatcagcagcagcaacaactgcagcagcagcaacagcatcagcgtGGCGTCTTCAAGCACAAGACgggcgatgatgatgaggaggaggatgatgatcagctgctgctgctggacgatGGCATCGGCGGCGACAGCAATGGTGGCAATGCCATGGGAGCGACTGGCAATCCGAGCACGATCAGCGCGAGCACGCTGAAGATACGGATACCGGAGGTGGCGTGCACAATTTGCGGTGCTCGGTTCACCGATCAGGAGATGTTCACCAAGCACATACAGAAGCACGAACAGGATCTGTATGTGGACAACCCGTTGGCGGCCATGTTCGATGATGGACCAGCGGACGCTGGACAATTTCAGGTGGAGCGCCAAAACGAGAACGGCGAATACGCGTGCGATCTGTGCGCCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGAATCCAATCATCGACGGCGAAGCGACAACGctgaacaacagcagcagcaacaacagcagcagcaacaacaacaacaacaacaattcaatgCTGCATCTGCGCGAACTGCATGCGGTGGGTTTGATGCCCAACCAGCAGcaccagaaacaacaacagctgcagctgcaacagcagcagcaacatcagcggaACAACACGTCGAGCAGTTCGAGCAAATCGCTGAAACGGAAACGTGAACTGAAATGCGATTACTGCGCCTCCACAttcatcagcaacaacaatctgcGTCGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCCACCTGCCAGAGCCGCCAGTGATTGAGGTGGACGAGCCGCTGACCTGTCGCCGGTGCGGTGATCTACGGTTCGAGACAAAGGAGCTGTGGATCGAGCATAAGCTGGCCGATGCGAAGGTGGTCCGTCCGTTCTGTCCGTTTCAATGGGGCTGCGATCTGTGCGGCGAGTATTTGTCGCGCAAGGAGAAACTGATCAATCACATCAACAATCATCTCAAGGAGGATGTGATTGTGCCGGTTGCAGTGGCTGTTGCCAAATCAGCGCCGAAtaaaaatacagcaaaaacaacagcggcagcaacaacaacatcagcagcagcaacaacagcagcagcagcagcaacagccacaaaggCAACAATCAAAACGAAGgccaaacagcagcaggaagagGGGGCGCAGGCGGAAACGGAGAAGGAGGCGCAGGTCGAACTAAATGCTGGCAAGCTGGCAAAGCAGGAGGATGATAGTGATATGGATGATAGCGATAGTGGGGATGATGAGGATAGCACAAGTGctggcgatgatgatgacgatgatgatgatgacgatgaggatgacgatgatgatgacgacgacgatgatgatgatgatgatgaagacgAAGATGttgtgcagcaacagcagctgctgcagcagaaacaacaacaacaacagcagcagcagccgcttaacagcaacaacaataacaataataacaacaacaacaacacgagtGTTGTGGCCAACGAAGATATCGATGATCTCATTGAGGAGGTCATCGAGGTTGATGGCATGGTCGAGGAACTGGACGATGATgaggacgatgacgacgatgacgatgacgatgatgacgatgtgGATGAAGTCGATGACGACGACGGAAACACCACAGATGAGCACCAGCAGCTGTCAGCCGCCAATGACAAGCAGCAGACGGAGCAGCGGGCGCAGCGGGAACAGCATCAGCCGCGACGACTCAACTTTGACTACAGCCGCACGGATAGCGCCAAGCTGAATGGCACCGGTAAACAAACGCTGGCAAAGTCGAagggacagcagcagcagcagcagcagtcggtTTTGGTCATGCACAGTTCCGAGGAGgatgatgaggaggaggaggacgatgatgttgatgatggtgtggatgatgaggatgaggatgcgGGTGGTGTTGGTGAGGCAATGACCATCGATGATATTATTGAAGAGGACGATGgtgaagatgatgatgatgatgatgacgatgacgatgatgtgGTTGGTGTCGGTGGTGCTGTCGTTGAGGATGATGATGTTGACGAAGACATGGACGAGGACGATGTCGACGATGTCGATGACGACGAtgtcgatgatgatgacgagcACATTGGCAACGGCGATGCACACAACAATGCGGCGCAAACCAGCGCCAGCGTTGttgatgccgatgccgatgcggatggggatggggatggtggcacatcatcatcatccgaGAGCGAgtcgacagcaacaacatcgcAGTCAATTGGTGAGCGgcgtaaaaaaacaaaagtagtTAAATCGGCGGCACATGGCGCTGCCGCTGATCAATCTAATTCCAGCTATACGTGTGATCTGTGTCAACTTTGTTTTGATTCTcaggagctgctgcagtcACATATTAAAAGCCATTTTCTCAATGGCCCAACGGCggtcggcagcagcagcaatgtcagcgccagcaacagcgccagcggcagcagcagcagcagcaaccgaagcagaagtagcagcagcaacggcgtCGTCGCCGCCAGtcgaagcaacagcagcagcagcaacaacaacaataataataatagtaataataataataataatactaataaaagcaaaaccaaaaagtcCGGATTGgatgctgcaacaacaacggcgacgacgacagcaacaacaacaacaacagcaactgttgcagctgtgCAGCCTGCAGCAAGCCTCAACTGA
Protein Sequence: MCDTVVTTVAAGTGTVTATGTGTGTGAAGAADTAATTTAMEERMRKSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITPLDRLSLHICHACISYLNSWQSFKNRCLSSQTKQRQWLETDKSKQQTLLGYLDLNKTENGSSTDHQQQHHELKNDSATAAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQQQHQQQQQQQQLQQQQQQLPHAARSTSAAADSQQSLQTLLLQVPSATLATTTAAASSLQQQQQRKQHQQQQRGRQQHHQQQQQLHQPYQQHQQQQPQQQQHHPQQRLSRIRQPRRQQQALSSQRLSKFRPKLYMPLDISVPAVPLPLPLPPPPPPVLSNVASAGAELAPLSLPLDFGQNQGQNQNLNQSQKVGGILPLPLPLPPPHPPPVATMSSNNAAVGSAAVTTPLLMPPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVAAAATLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGYDYDSPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRIKQPNFSHANASGLTVTADGQQQLQQHQQQQQQMIVGGEASTERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVGSDNASTANSGGLDHSPGKRSLLGALGIGVSQSSNEESRSSGHHNNNASEAPLTSTPKLTAAGLGGTAAATAATGAAAATSGGSTSGNRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDEEESGSIAKKMRLDDSSNNSSINMSLANQQKECLICNAVFSNNIGLSNHMRSHYTASTATSAALAAANRMTPKSLTITATPPLEAAVVSSTASAPATTTAAAAVVATTATAAATTATTTAAAVAAAGGNLPPAMANQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIVKQFECDICSIVYSNELELQQHKRSVHKSHSGSAASDSNKSNKSATATATSAELAETSGTAVTTLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECNLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQLQQQQQHQRGVFKHKTGDDDEEEDDDQLLLLDDGIGGDSNGGNAMGATGNPSTISASTLKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTLNNSSSNNSSSNNNNNNNSMLHLRELHAVGLMPNQQHQKQQQLQLQQQQQHQRNNTSSSSSKSLKRKRELKCDYCASTFISNNNLRRHMYELHKHEVSHLPEPPVIEVDEPLTCRRCGDLRFETKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVAVAVAKSAPNKNTAKTTAAATTTSAAATTAAAAATATKATIKTKAKQQQEEGAQAETEKEAQVELNAGKLAKQEDDSDMDDSDSGDDEDSTSAGDDDDDDDDDDEDDDDDDDDDDDDDDEDEDVVQQQQLLQQKQQQQQQQQPLNSNNNNNNNNNNNTSVVANEDIDDLIEEVIEVDGMVEELDDDEDDDDDDDDDDDDVDEVDDDDGNTTDEHQQLSAANDKQQTEQRAQREQHQPRRLNFDYSRTDSAKLNGTGKQTLAKSKGQQQQQQQSVLVMHSSEEDDEEEEDDDVDDGVDDEDEDAGGVGEAMTIDDIIEEDDGEDDDDDDDDDDDVVGVGGAVVEDDDVDEDMDEDDVDDVDDDDVDDDDEHIGNGDAHNNAAQTSASVVDADADADGDGDGGTSSSSESESTATTSQSIGERRKKTKVVKSAAHGAAADQSNSSYTCDLCQLCFDSQELLQSHIKSHFLNGPTAVGSSSNVSASNSASGSSSSSNRSRSSSSNGVVAASRSNSSSSNNNNNNNSNNNNNNTNKSKTKKSGLDAATTTATTTATTTTTATVAAVQPAASLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00561176;
90% Identity: -
80% Identity: -