Dnig012148.1
Basic Information
- Insect
- Drosophila nigricruria
- Gene Symbol
- -
- Assembly
- GCA_037075265.1
- Location
- JBAMCI010000160.1:6197748-6201812[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00092 0.066 13.8 1.2 1 23 206 229 206 229 0.97 2 12 1.6e-05 0.0012 19.4 2.0 1 23 234 257 234 257 0.96 3 12 6.8e-05 0.0049 17.4 2.2 1 23 262 284 262 284 0.98 4 12 5.4 3.9e+02 2.0 4.5 2 23 291 314 290 314 0.89 5 12 0.00049 0.035 14.7 1.0 3 23 324 345 323 345 0.95 6 12 0.0038 0.27 11.9 0.1 1 23 351 374 351 374 0.95 7 12 0.26 19 6.1 0.2 5 23 390 409 385 409 0.89 8 12 3e-05 0.0022 18.5 0.4 1 23 439 461 439 461 0.98 9 12 2.3e-05 0.0016 18.9 4.3 1 23 467 489 467 489 0.96 10 12 9e-06 0.00064 20.1 0.1 2 23 496 517 496 517 0.97 11 12 0.0012 0.087 13.4 0.9 1 23 524 546 524 546 0.99 12 12 0.00036 0.026 15.1 3.9 1 23 552 575 552 575 0.98
Sequence Information
- Coding Sequence
- ATGGAAACGTGTCGCACCTGTGCAAGGTGCGATTTCGAAAATGGCAACAACTATTGGCTGGATATGTTTCATCCAACCCGTTGGCAGAGTGAAATGGCGCAAATACGCGCAGAATTCGGCAACTGGAAGTTACAGaTCGCACCAAACGATGGACTGCCACAAAAAATATGTAGCGACTGCTTTACAAAGTTCTGCTCAGTTTACACGTTTCGCATGGCCTGCCAGGACGCGCAATTGAAGttgtcaaatatttttgataaaatCGATGTGAACTTGCTGTATGACAGAAATGATGAAGAAAACATTGAAGTTGATGCTGATGAGCCAGAAGCAACTACAAAAATATGTACAGTatcagaagcagcaacaacaacagaaaacacTGCCATCAATGCGGAAAGATCGCCCACACCCATAGAAATCTTTGTGGAAACGATTAGCATTAACGAAACCGAATCCTTACAGCCAGAAGATAAAGAAGTCGACTTAGTTTCAGATTGTAATTCCTTAAACATAAGCTATGCTTGTAAATTCTGCTATAAGCCACAAGAAAGCTATGAACTTCAGCACCTATTACTAGAGCACATAAGCTTCTGCCACGATCCGGATCAGCCCTACAACTGTCCAGAATGCACTGAGTGTTTTCAAGACACAGCATCGCGTACCGTCCACATGAAGAGCGTTCATGTGGTTAAGCACTATGCCTGTGAGGTCTGTGGCAAAAAGTACGGAGATCGCCACAATCTGGAGCATCACATTGAGAAGTATCACTCGGAAACAGATTTCGAGTGCAGCATGTGCGAGAAGCGATTTTTTACGCGCAAAAGCCTGCTTTACCACATGAACTGGCACAAGCCGGAGCGTCAGCTCCGATGTCGTCACAGCGGCTGCGACCGGCTGTTTATCAATCAACGACATCTCATATGTCACGAAGCAACCCACACAACGGGCTCCCGCAAGAGCGAGTATTGCGGCTTTTGTGGCAAAGCTTTTATACATGTTAAGACCCTTCGTTGGCATATCTATCGACAGCATGGCGGAGAGAAGCCTTTCAAATGCGCCATCTGCACTGAGGTGTTTGCCTCGTATGTGGAAAAGCGCATTCATATGCTTGAGCAGCACACGGAGAATCTGACCCATCAGGAGCGCAGCGAGTGCATGTTTCAGTCCTGTCGCCAGGAGTTCGACAACGAGCAGGAGCTCGTTCAGCACATGACCATGGAGCATGTACAGCGCGAAGCCTCCTCTACGCCGATCATTGCGAACAATAAGCGAGTGATCCAATGCAAAAGGGAACGACAGTACACGGGTCTCTTCCAGTGCGGCAGCTGCACCCAACGTTTCAACATGAAGTCCGCCTTGGAGCGTCACATGGCTGTCCATTCGACGGATCGGCTGCATGCCTGTGCGCACTGCTCCAAGCGCTATAAGCGTGCTCAGGATCTCAAGTGGCATATGAAGACCCATGACAATGAAAAGCCCAATGTGTGCGACGTTTGCGGCAAGGCTTTTGCCCTGAAATATGTCCTAACTCAGCATATGCGCAGCCATGAGGTTCTCGAGAAGAATTTCAAGTGTGAGACCTGTGGACGGGCGTATCTGTTTGAGAAGTCCTTGCGTCTGCATCAACGCGTACACACAGGCAATACCTACTACAAATGCGATCTGTGCCAAGAGCGATTCGTCACGCACATCAAGTTTAAAACTCATATGAAGAAGGCACATGACGGCAACCAGTCGCATTCTAAGGATACGCTGGATGATTTGATCAATATTGTGATTAACTAA
- Protein Sequence
- METCRTCARCDFENGNNYWLDMFHPTRWQSEMAQIRAEFGNWKLQIAPNDGLPQKICSDCFTKFCSVYTFRMACQDAQLKLSNIFDKIDVNLLYDRNDEENIEVDADEPEATTKICTVSEAATTTENTAINAERSPTPIEIFVETISINETESLQPEDKEVDLVSDCNSLNISYACKFCYKPQESYELQHLLLEHISFCHDPDQPYNCPECTECFQDTASRTVHMKSVHVVKHYACEVCGKKYGDRHNLEHHIEKYHSETDFECSMCEKRFFTRKSLLYHMNWHKPERQLRCRHSGCDRLFINQRHLICHEATHTTGSRKSEYCGFCGKAFIHVKTLRWHIYRQHGGEKPFKCAICTEVFASYVEKRIHMLEQHTENLTHQERSECMFQSCRQEFDNEQELVQHMTMEHVQREASSTPIIANNKRVIQCKRERQYTGLFQCGSCTQRFNMKSALERHMAVHSTDRLHACAHCSKRYKRAQDLKWHMKTHDNEKPNVCDVCGKAFALKYVLTQHMRSHEVLEKNFKCETCGRAYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKKAHDGNQSHSKDTLDDLINIVIN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00502704;
- 90% Identity
- iTF_00573493;
- 80% Identity
- -