Basic Information

Insect: Drosophila multiciliata
Gene Symbol: zfh1
Assembly: GCA_037043605.1
Location: JBAMBF010000344.1:1237806-1269721[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.017 1.2 9.7 0.7 3 23 85 106 83 106 0.93

2 9 0.003 0.2 12.1 1.4 1 23 303 325 303 325 0.97

3 9 2.6e-05 0.0018 18.6 2.7 2 23 340 361 339 361 0.97

4 9 3.9e-05 0.0026 18.0 6.4 1 23 370 392 370 392 0.99

5 9 5.1e-05 0.0034 17.7 1.6 1 21 398 418 398 419 0.95

6 9 0.03 2 9.0 0.4 2 21 709 728 708 729 0.92

7 9 1.5e-05 0.001 19.4 0.5 1 23 1079 1101 1079 1101 0.94

8 9 5.5e-05 0.0037 17.6 7.4 1 23 1107 1129 1107 1129 0.98

9 9 0.0028 0.19 12.2 4.3 1 21 1135 1155 1135 1156 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.017	1.2	9.7	0.7	3	23	85	106	83	106	0.93
2	9	0.003	0.2	12.1	1.4	1	23	303	325	303	325	0.97
3	9	2.6e-05	0.0018	18.6	2.7	2	23	340	361	339	361	0.97
4	9	3.9e-05	0.0026	18.0	6.4	1	23	370	392	370	392	0.99
5	9	5.1e-05	0.0034	17.7	1.6	1	21	398	418	398	419	0.95
6	9	0.03	2	9.0	0.4	2	21	709	728	708	729	0.92
7	9	1.5e-05	0.001	19.4	0.5	1	23	1079	1101	1079	1101	0.94
8	9	5.5e-05	0.0037	17.6	7.4	1	23	1107	1129	1107	1129	0.98
9	9	0.0028	0.19	12.2	4.3	1	21	1135	1155	1135	1156	0.96

Sequence Information

Coding Sequence: ATGTTGTCCTGTTTGGCGCCATCGTCTACACGTTGTTTTGGCCAAGAGGATAACATAATAATACAGCAGAGTATGCCATCTTCCACAGCCTTCTCCATGCAGTTTCCCTCTCTGGCGTCCAGTTTACACCATCATCAaaccacaacacacaacaacagccagcCAAGCAATGTGGCCGCAGCCAGTACGGAGCATGTGCCACATGCAACCAGTGCTGCCACAGCGAATGCGGCCGATGAGTGTCTGGTCATATGCCCCCAATGCCACAAGCGCTTCAATGAGTTTCAGTTATTTAGCGAGCACATTGCCAGCGAGCATCCGCTGGACAAGCTGAACTATGAGCAGCCGCATCCAGGCGCAGCTCAGCCGGAGAGCGAGcccgaggaggaggatgaggaggaggagcacaGCAATctgagcagcggcagcaatcCTCGCTATGCCAAATCcccaagcaacaataacaacaacaacaacaacaataacaacaacagtcacaacaacaataacaataataataatagtgaaACGGCAAAGAATCAAAACAAACGCATTTCACATTCACCCGCCTCGCTGGGCTCCCCCGTTGCCCCCGCCACGCCCAGCGATCTGTTTGCCCATCTGCCACACCCTGCCGcccatttgcaatttgtggcagCCGCAGCGATGGCCATGCAATCGGCACGCTCAGCTAACTCACCCAgcaaccaacagcaacagttgcaacaacaacagcaacaacagcaacaccagcaacaccagcagcagcagcaacagttgctacAGAAgccgagcagcaacagcagcagcattggcaGCAATTCCGCCTATGATCTGGATCTGAGCGCCCATCGTTCCACCTCGAGTCCCGGCTCCACAGCTGGCGGAGATCTGCCAGCTGCCGGCTTCCCCTGCATGCAGTGCACAGCCACCTTCCACAATCGCGAGCAACTCGAGCAACATCAGCTGCTCCACTCGCCGACGAGGCAACACACAATCGCACAAAATGTCAAACAGACCTGCAAAATCTGTCACAAGACTTTCGCGAATGTGTATCGCCTGCAACGACACATGATTAGCCACGATGAGTCCGCGCTGCTGCGCAAATTCAAGTGCAACCAGTGCGAGAAGGCGTTCAAGTTCAAGCACCACCTGAAGGAGCACGTGCGCATCCATTCCGGCGAGAAGCCCTTCAGCTGCGACAACTGCGGCAAGCGATTCTCGCACTCGGGCAGCTTCTCTTCGCACATGACATCTAAGAAGTGCATCAGCATGTGCCTCAAGCTGAACAACAATCGCCAGCTGCTCAAAACGCTGGACAAGAATGCGGAGCAACTGCCGCCAACTAAGCGTTCGGCCTGCAAACAACTGGTGGAACCGGTTCTCCCAAATCTGCCCATGAATTATTTTGCTGGTGATTCACAAACATCTCcggttggagttggagttgctggcggtgctgcagctgctgttcctCCTCCGCCTCACTTTTATCCCAATTATAGCGCAATGAATGCGGCTTTGTTGGCCTTTCCTAATGCTTTTATGGCGGCTGCCTTAGATCCACGCATGCATCCCTATAGCATACAGAGATTGCTGGAGCTAACAGCGGcaggacaacagcagcaccaacagcagcagcagcagcagagggaggaggaggagcagcacagagagcagcaggagctgaagagggagcaggagcaggagttaGAAAgggaacaggagcaggagagggaaagggaaagggagcagcagctgcagagagagcagcaggagcagcagcgggTGAGGGAGCAGGCGCAGCGCGagcagttgcaattgctgccTAGCAAACAGGAGGAGTATGCAGAGGAGCCCAAACTGGTCATGGATCTGGAACAGGATGTAGAGCAcccagtagcagcagcaacagtggaaGCCAAGACAGCTGTCAAAATGGAGATCTGTCGCGAGACAACGCCACAGCCCACAGAAGCACTCAAAGCTATCAAGCAGGAacgggagcaggagcaggaacaggaggAGCAAATGGAGCTGGACATGCAAATGGATCTGGAgaaggaacagcagcagcagcagccaccttCCCCGGTGGCCATGCCCCAGTCGAGCCCGGAACTGCGTTGCAGTCGCTGTGCGAAGCAATTCAATCATCCCACCGAGCTGGTGCAGCACGAGAAAGTGCTCTGTGGCCTGATCAAGCAggagctgcaacagcaacactatcaacaacagcaacagcagcagcaacagcagcagcaacaacaacagcaactccagcagcagcagcaactgcagcaaactCCTCGTTCCCTTTCCGATTACGATGACGACGAGGATGTGGAGGAGCTGCTGGAGGAGCCACGCCACGCGGACTACGCCGCCGGCAGCAGTGATAGCAATGAGCGCAAGGTGCGCGTTCGCACCGCCATCaacgaggagcagcagcagcagctgaagcagcacTATGCCCACAATCCGCGACCAAGTCGCGACGAGTTCCGCCGGATTGCTGCCCATCTCCAGCTGGATGCGCGGGTTGTCCAGGTGTGGTTTCAAAACAATCGCTCGCGGGAGCGCAAGCTGCAAAGCTACACAAGTGGCGGCGCTGGCAACACTGAGACGGCCTCGACAATCCTGGCCAGCTCTGCTGCACTGCCACCCACACGTGGCGAGGATCAGCCCTTGGATTTGTCCCTCAAGCGGGATGCAACGCcgccgcagtcgcagttgcagaTGCCCCCGGATTACAGTGAGGCCAGCATGGCCATCAATTTGAGTCGCCGCCAGTTGTCCAGCTCCGCGGCGTCTGCCATGTCGCCAGCTTCCCtcgcagcggcggcggcggcaactcTTTACTTTGCCCCACCCTCGCCGACGGCGGGCCCGTTGCACAGCTCCACACCTCCTTTGGGCGCACAGCGGGGCACGCCCTTTGCCGGCCTGCCGCCCTTTCCCATGATGGCCCGCCTGCCCATGGAGGCGCTCTTCCAGATGCGTCCCGGCGGCGAATATGCGCCGAATCCTCTGATGAACAGTATTAAATTGCCGGACTATCATCGCGGCACCAGCCTCAGCCCGGGTGGCTCTGAGAAGCGTTCGTGGCGTGACGATGATTCGCGCATTTCCCACGAGGATGACTATGTCCTGGCCACCGGTGGCCTGCTGGCCCCCAAACCGAGACGTGCCAAGGCCGAGACCCATGGACATGCCGGCGATCCCGATCTGCCCTTCGTGTGTGATCAGTGCGACAAGGCGTTCGCCAAACAGAGCTCCTTGGCCAGGCACAAATACGAGCATTCCGGTCAGCGACCCTATCAGTGCATGGACTGCCCGAAGGCCTTCAAGCACAAGCATCATCTGACGGAGCACAAGCGATTGCATTCCGGTGAGAAGCCGTTTCAGTGCTCCAAGTGTTTGAAGCGCTTCTCGCACTCGGGCAGCTACAGTCAGCACATGAACCACCGCTACTCCTACTGCAAGCCGTACAGGGAATAG
Protein Sequence: MLSCLAPSSTRCFGQEDNIIIQQSMPSSTAFSMQFPSLASSLHHHQTTTHNNSQPSNVAAASTEHVPHATSAATANAADECLVICPQCHKRFNEFQLFSEHIASEHPLDKLNYEQPHPGAAQPESEPEEEDEEEEHSNLSSGSNPRYAKSPSNNNNNNNNNNNNSHNNNNNNNNSETAKNQNKRISHSPASLGSPVAPATPSDLFAHLPHPAAHLQFVAAAAMAMQSARSANSPSNQQQQLQQQQQQQQHQQHQQQQQQLLQKPSSNSSSIGSNSAYDLDLSAHRSTSSPGSTAGGDLPAAGFPCMQCTATFHNREQLEQHQLLHSPTRQHTIAQNVKQTCKICHKTFANVYRLQRHMISHDESALLRKFKCNQCEKAFKFKHHLKEHVRIHSGEKPFSCDNCGKRFSHSGSFSSHMTSKKCISMCLKLNNNRQLLKTLDKNAEQLPPTKRSACKQLVEPVLPNLPMNYFAGDSQTSPVGVGVAGGAAAAVPPPPHFYPNYSAMNAALLAFPNAFMAAALDPRMHPYSIQRLLELTAAGQQQHQQQQQQQREEEEQHREQQELKREQEQELEREQEQEREREREQQLQREQQEQQRVREQAQREQLQLLPSKQEEYAEEPKLVMDLEQDVEHPVAAATVEAKTAVKMEICRETTPQPTEALKAIKQEREQEQEQEEQMELDMQMDLEKEQQQQQPPSPVAMPQSSPELRCSRCAKQFNHPTELVQHEKVLCGLIKQELQQQHYQQQQQQQQQQQQQQQQLQQQQQLQQTPRSLSDYDDDEDVEELLEEPRHADYAAGSSDSNERKVRVRTAINEEQQQQLKQHYAHNPRPSRDEFRRIAAHLQLDARVVQVWFQNNRSRERKLQSYTSGGAGNTETASTILASSAALPPTRGEDQPLDLSLKRDATPPQSQLQMPPDYSEASMAINLSRRQLSSSAASAMSPASLAAAAAATLYFAPPSPTAGPLHSSTPPLGAQRGTPFAGLPPFPMMARLPMEALFQMRPGGEYAPNPLMNSIKLPDYHRGTSLSPGGSEKRSWRDDDSRISHEDDYVLATGGLLAPKPRRAKAETHGHAGDPDLPFVCDQCDKAFAKQSSLARHKYEHSGQRPYQCMDCPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00497631;
90% Identity: iTF_00577278;
80% Identity: iTF_00552203;