Dmul012786.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila multiciliata
Gene Symbol
hang
Assembly
GCA_037043605.1
Location
JBAMBF010000584.1:264407-280656[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.35 24 5.6 1.0 3 23 515 536 514 536 0.93
2 17 0.66 44 4.7 3.5 3 22 641 660 639 660 0.89
3 17 0.00076 0.051 14.0 3.3 1 22 781 802 781 804 0.90
4 17 0.00088 0.059 13.8 0.2 2 23 976 998 975 998 0.95
5 17 0.00056 0.038 14.4 0.2 1 23 1006 1029 1006 1029 0.96
6 17 0.00019 0.013 15.9 0.2 2 23 1120 1141 1119 1141 0.97
7 17 0.00036 0.024 15.0 2.9 2 23 1254 1276 1253 1276 0.97
8 17 0.028 1.9 9.0 0.2 2 23 1285 1307 1284 1307 0.95
9 17 0.0088 0.59 10.6 0.2 1 22 1320 1341 1320 1343 0.90
10 17 0.00016 0.011 16.1 1.1 1 23 1402 1424 1402 1424 0.99
11 17 0.0025 0.16 12.4 0.9 1 23 1432 1455 1432 1455 0.96
12 17 0.11 7.2 7.2 0.5 2 19 1463 1480 1463 1481 0.95
13 17 0.0029 0.2 12.1 0.1 3 23 1585 1605 1584 1605 0.98
14 17 0.0013 0.089 13.2 0.1 1 23 1640 1662 1640 1662 0.97
15 17 0.00075 0.05 14.0 0.6 2 23 1746 1768 1745 1768 0.93
16 17 0.0081 0.54 10.7 0.3 3 23 1824 1844 1824 1844 0.98
17 17 7.6e-05 0.0051 17.1 1.4 1 23 2302 2324 2302 2324 0.99

Sequence Information

Coding Sequence
ATGTGCGACgctgccgcaacaacaacaactgcagcagcagcagcacaaggaACAGAAGCTGCTGGCGATACAGCGATGGAAGAACAAAATCAGCGAGAGCGACAAAGCTGCTGTCGCCTGTGCGTTGCGCCCGCCAgcgaatgcatttcaattattaacaGTTATGCGGCCGATAAGGAACCATTGGCCACTAAAATACACAACTGCGTAAATATCAAGatcACATCGACGGATCGTCTTTCGCTGCATATTTGCCATGCCTGTATCAGTTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCTTCAGCTCACAGACGAAGCATCGCAAATGGCTTGAGAATGACAAAACCAGGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGAGCCGAGAATGGCAACACAGCTGAGctacaccaacagcagcagcacgattTAAGAATGGATTCTGCGACGGCTGCAGCTGAGAAGGCTTCCGCTGCCAACATTTTGGATGGCATACCTCAGCTGCAGAAACGCAAATCGTTAACAGTCTATGTGAGtccaaagcaacagcagcaagcacagcaacaacagtcgcagcaacatgcgcagcaacagcatgcAACAGTGGCAAGATCAACGTCGAAAAcatcggcggcggcggcagtggCGGAGTCGCCAACAACATTGCAAACCCTTTTATTGCAGGTgcccacaacagcagcatcagcagcagcagcagcgacattAGCAACGGCGTCaacactgcaacagcaacagcagcgcaagcagcaacaccatcagcagcagcaacgtggcaagcagcagcaacctcTACAgtatcatcaacagcagcaacagcatcgacAGAGTCGCATCCGCCAACCGCGACGACAGCAACAAGCGGCAACCGCCAAATTCAGGAGCCAACTGTTTGTGCCATTGGATATATCGGTGCCGGCACTGCCGGCATTGCCAGTGCTGttgccgccaccaccgccagctgttgctgatgcagcGTCGTTGCTAttgccgctgtcgctgccacTTGATTTCAGTcagaatccgaatccgaatccaaACCCATATCCAAATCCCAATCAGTGTCCAAATCCTAGTCAAAATCCAAATCAGAGATTTACAAGTAGCGTTTTagtgccgccgccgccgccgctgcccccagcagttgcaacaatgaGCAGCAGCGAGGCAGCCATTGCCACTGGCTGTGGTGCAACTGctactgcaactgcaactgcaaccgcaACCGCAGTCACGACTCCATTGCTCATGCCGCCGTTGCCTGCCATGCACATCAAGGATGAGCCCCTGGACGATACGGATGATGAAATGAAGTGCTTAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAAGGCGATGTGCCACTAAATACCTCCGACTATGATTATACGGCTCAGCATGGCGTGACCGCTGTTGTGGCAGCGGCATCGTTGCCCGCCAGCGCTGTTGCAAATGTGGCCGCCGCTGGTGACTCCAAGGTGGCCAGCTGCCGGGCTTGCAGTCTGCAGTTCTCGACGCGTGCAAATGCTCGTCGCCACGAGCGCAATCTGCATCCGAATCTGTTCCAGTTGTCGACAGACTCACCAAATAATACGCCGATCACAAAACCGACACCGGCTTTGGCCGCCGCATTAGAGTTGCAgcgtgcagctgctgcggcgaCCGCTGAGGCAACACGTGCCGCTGCCGGTGGCAATATATCGGCGCAAAAGTACCGCCAGGTGGTGATGAACACGTTCATGAAATGCGAGAACGGCGGCTTCGACTACGACAACCCGGAACAGTATCAGGAGCTGTTGTCCCACGACAAAGTTGACTTTCTACAGGAGAACAGCGAATTTCTCGAACAGTACCAGACGATGACGTGCCGCTGTTGCAGCAAGTTCTTCAGCACGTACAAGAACTTCATGGCGCACGTGCGCAAGAAGTATCCGTTGCTGCCACGCAACCTGTGCTTCAATTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCACCTGAAGAAGCGCAACTGCATCAATCTGTATCGTGTGCTAAACGCACTGCGCACCAAACAGCCAAGCTTTGTCCATGCCAATGCTTCATCCAGTAGCACTTCAGCTATTGCGGCAGCGGCGACATCTCTGCTGCAGTTGGCGACAGCAAACGAAACACcagaaaaagcaacagcaacaggaacagcaacaggaacagcatcaggaacagcaacaggaacagcaacaacatcaacggaTCGTCCGGAAAAGTTGCGTGCCAAGGAGCTGCTGGTTAACAAGCTGTACGAGTGCAAGCTGTGCCCAAAGGGCTTTCGCACCAAGCACGAGTTCCGCACCCATGTCTATGATAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTTGCTTGGACTTTGCCGATCCGGTGGATCGTCGTAGGCATTACAATAACATGGATTGCATTGTCCGTCTGCGCTGCATGACCTGTGATGCCAAACTGGAGACGCATCAGCGCTTTCTCGACCATGTCTATCAGGATCATTTGGGTGGCGTGAGCAGTGATAATGCCTCCTCGACGGTGGCAACCACCACTCCCGTGGATCCCTCGATTATCAAACGCAACTATATGGTCGCCTTTGGATTCCGTCAATCATCCAATGATGAGtcgcgcagcagcaacagcaacaacaataataataacaacagcaataataacaacaacaataatacacTTTTAACCTCGACACCCAAACCACCAACGGGATCAGGAGCAGGCACAGCTGGTGCAGGTGCAGCAACCAGTGGTGGGTCAACAACATCGGGCCATCGTGATGCACCCAAATCGCAGTATTTTTCACGAATGCCACAAGTCTGTCCGATCTGTGGCCAGCAgtacaacaactataacaatgTGCTGCGCCACATGGAGTCCAAGCATCCCAACAAATTGCCAGAGACATACAAATGTGTGCGTTGCGGCCGGGGCTATCCACGCATCTCCTATCTGCGGGAGCACATGATCAATGTGCATGGCGTGGGCAAGAATCGCAATTCGGGCGGCTTTGAGTATATTGTGAATGCCGATGCGGTTAAGCTGGCGGATGGCAGTGCACCCAATGTGTATGCGGGTCGATATGATTATGTGATGAAGGATTTGATGTCTATAACAAATGGTGGGACTCTcgatgatgatgacgaagaAGTCGGCGTTGTACAGAGTTGTAAGAAGGTACGATTggacgacagcagcaacaacagcagcagcaacaacaacaacaacaacattgccaACCAGCAGAAGGAATGCCTCATCTGCAATGCGGTGTTCAGCAACAATATTGGTCTATCCAATCATATGCGTTCCCATTACACGGCATCGATAACGACTCTGGCGGTGGCCAATCGCATGACGCCCAAATCGCTGACAATCACAGCAACGCCGCCGCTTGAGGTCACAGccacggcaacggcaacatcaTCGCTAGCAACGAGCACAGCAAACAACACATCGACTGCTGCTCCAACAaagacaacatcaacaattgTTGCAGCGGTGCCAACGGCAACCACAACAGAAACCGGAACAGCAACTACATCATCAGGCGGCAAACTGCCGCCAGCAATGGTGCATCAGACGGCACAGGAGCAGGCGGTATTCCGCCGTAGTCTGGACCAGGCGGCCGATCGACGTTTCCGTCGCATGCGTTGTCGCATCTGTCAGCGCAGATTCAGTTCCAAGAAATCGTATCGCTATCACATGCTGACCGACCACCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCGGAGTTCGCCTACGAGAAGGGGCTCAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATCAAGGACGAGATGATTATCAAGCAATTCGAGTGCGATGTCTGCTCCACCGTCTACAGTTCCCAGCTGGaattgcagcagcacaagTACGCCGTGCACAAGTCACAAGCGAGTGagtcatcatcatctgcagcagcagcagcagcagctagtGGCAAACATTCATCGAAATCATTGACTGCTACTGCTACCTCCACAACTGACCTGATGGCAGAGGCATCAAGCTCCATGACGGGCACGCCGGGTGCGGCCCATCTGCTGCCACTCTATTGGTACCAGTGCAAATATTGTCCATCCAACTTCAACACCAACAAGAAACTAGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCCTGCAAGGATTGCGGCAATGTCTACAGCGGCCGCAAGAGCCTTTGGGTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGCCGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAACCATAAGCCCACCTGCAATCGCAAGCCAATCACTGCCACCGGCGCCCATCAGCaggatcagcagcaacaacagacccaacaacagcagcatcaccaTCCGCAGAAACATCAGCGGATCGTCTTCAAGCACAAAACgggcgatgatgatgacgaggaTGAGGGCGACGATCAGATGCAGCTAATGGATGATGGCGGTAACGGCAGCAATGATAGCATTGCTGGCAATGCCATTgcatcgacagcagcagccgctgcagctgcagctgcagctgcagcagcagcagccacattgAAGATACGCATTCCGGGAGTGGCTTGCACCATTTGCGGTGCACGGTTCACCGATCAGGATATATTTGCCAAACACATACAGAAGCATGAACAGGAACTGTATGTGGACAATCCGTTGGCGGCCATGTTCGATGATGGGCCAGCGGATGCCGGACAATTTCAGGTTGAGCATCAGAACGAGAATGGCGAATACGCGTGCGATTTGTGCACCAAGACGTTCCCCCAGGTGATAGCACTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGaTTCCAATGCTCGACGAAGCGACAACGctgaacaacagcagcaacaacagcagcagcagcaacatctacaacaacaacaacaattcgctGAGCGCATCATCGATGCTGCATCTACGCGAACTGCATGCGGTTGGCCTGATGcccaatcagcagcaacaccagaaacaacaacagctgccgcagcagcagcaacggacGAGCAAATCAATGAAACGGAAACGTGAACTGAAATGTGAATATTGCGCCTCCACATtcattagcaacaacaacctgAGACGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCGGAGCCGCCAGTGATTGAGGTGGATGAGCCGCTGACATGTCGCCGTTGCGGCGATCTGCAGTTTGATACCAAAGAGCAATGGATCGAACATAAGCTGGCCGATGCCAGAGTGGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTCTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTGATTGTGCCCGTCGCCAGCAAGCTACCAGCAACGGCAGTCAACAACACCGCaaaaaaatcagcagcagcagcaacaacaacagctgccgcagcaaatgttgcaaatgctacatcagcaagagcagcagcagcagcagcagcaacagcaacagaagaaCTTAAGGCTAAGCAACACCACCTGCGGGAACAGGCAGAAGATGAGGGCGATGTGAAGCTAACGAAGCAGCAGGAAGAAGATGATAGTGATATGAATGATGAAAGCGAGAGtggcaatgatgatgatgaggagggcagcagcagcagtgctgatgatgatgacgacgacgatgaagatgaagatgatgatgacaatgatgatgatgatgacgacgacgaagaagaagaagacaacgGCAATCGTGAAAATATTGCtgcacagcagcaattgctgcagcaagaaaatacaaacaccaacaacatcaactcccccgaaatcagcagcagcacaattCAGAATGACGATGATCTCATCGAGGAGGTAATCGAAGATGATGGCATTGTCGAGCAGCTGatcgacgatgatgatgatgaagaagatgacgatgatgatgaggatgaagATGATGAGGACGACGATGGTGACGATGAGGAGGgggaggatgatgatgatgaggaacATCAGCCAAGACGCCTCAATTTCGATTACTCAAGCAATTACAGCGCCAAGCTAAATGGCAACGATGGCAAAGAGTCTGTGGCAAAATCAAAGGGGCAGACACTTTTGCCGCAACAGCCAATGCTGGTCGTGCGCACCACAAGTAGTAGTCGCCACGGAGGAGATGGCGAGGAGGACGATGTGGATGATGTGGATGATGTGGATGAGGATATTTTCACAGTTGGCGGTGAAGCGATGACTATTGATGATATTATTGAAGAGGATGATGGTGTGGATGAAGACGATGTGGTTGGTGTCAGTGGTGGTGTTGTTGaggataatgatgatgatgatgaggatgaggatgatgacggcgatgacgacgacgatgacgataatgctaatgatgataatgatgatgatgatgatgaagatgatgatgatgatgttgatcaTGTTGATGGTGGTGTTAATGAAGTTGTAGAGGAGGacaaagatgatgatgatgctggcAACGAGGAGAATGCCGATGTCGACAACTCCAACATTGGCAACGGTGTTGGACGTGTGGCTCAAGATGCTGATCGTGATGATGATAGCTATGATACATCATCATCTGAGAGCGAGTCGACCACATCACAATCAACTGGTGAGAGGCgtaataagaaaaaagtagTTGCATCAGCGGCACATGGTGCTGCCGCTGATCACTCTAATTCGAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAACTTCTTCAGATTCATATTAAAAGTCATTTCCTCAATGGGCCGTCGCTTGGATGcaagaagacaacaacaacaacaacagcagcagttaaagctgcagcagccgaTGCTGCAACGGGCTTCAACTGA
Protein Sequence
MCDAAATTTTAAAAAQGTEAAGDTAMEEQNQRERQSCCRLCVAPASECISIINSYAADKEPLATKIHNCVNIKITSTDRLSLHICHACISYLNSWQSFKNRCFSSQTKHRKWLENDKTRQQTLLGYLDLNRAENGNTAELHQQQQHDLRMDSATAAAEKASAANILDGIPQLQKRKSLTVYVSPKQQQQAQQQQSQQHAQQQHATVARSTSKTSAAAAVAESPTTLQTLLLQVPTTAASAAAAATLATASTLQQQQQRKQQHHQQQQRGKQQQPLQYHQQQQQHRQSRIRQPRRQQQAATAKFRSQLFVPLDISVPALPALPVLLPPPPPAVADAASLLLPLSLPLDFSQNPNPNPNPYPNPNQCPNPSQNPNQRFTSSVLVPPPPPLPPAVATMSSSEAAIATGCGATATATATATATAVTTPLLMPPLPAMHIKDEPLDDTDDEMKCLDESDDMMDPTMFLERSEHEGDVPLNTSDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALELQRAAAAATAEATRAAAGGNISAQKYRQVVMNTFMKCENGGFDYDNPEQYQELLSHDKVDFLQENSEFLEQYQTMTCRCCSKFFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRTKQPSFVHANASSSSTSAIAAAATSLLQLATANETPEKATATGTATGTASGTATGTATTSTDRPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCCLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASSTVATTTPVDPSIIKRNYMVAFGFRQSSNDESRSSNSNNNNNNNSNNNNNNNTLLTSTPKPPTGSGAGTAGAGAATSGGSTTSGHRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGRGYPRISYLREHMINVHGVGKNRNSGGFEYIVNADAVKLADGSAPNVYAGRYDYVMKDLMSITNGGTLDDDDEEVGVVQSCKKVRLDDSSNNSSSNNNNNNIANQQKECLICNAVFSNNIGLSNHMRSHYTASITTLAVANRMTPKSLTITATPPLEVTATATATSSLATSTANNTSTAAPTKTTSTIVAAVPTATTTETGTATTSSGGKLPPAMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSQLELQQHKYAVHKSQASESSSSAAAAAAASGKHSSKSLTATATSTTDLMAEASSSMTGTPGAAHLLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHKPTCNRKPITATGAHQQDQQQQQTQQQQHHHPQKHQRIVFKHKTGDDDDEDEGDDQMQLMDDGGNGSNDSIAGNAIASTAAAAAAAAAAAAAAATLKIRIPGVACTICGARFTDQDIFAKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVEHQNENGEYACDLCTKTFPQVIALKVHRKWHFRGDSKQIPMLDEATTLNNSSNNSSSSNIYNNNNNSLSASSMLHLRELHAVGLMPNQQQHQKQQQLPQQQQRTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDLQFDTKEQWIEHKLADARVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVASKLPATAVNNTAKKSAAAATTTAAAANVANATSARAAAAAAATATEELKAKQHHLREQAEDEGDVKLTKQQEEDDSDMNDESESGNDDDEEGSSSSADDDDDDDEDEDDDDNDDDDDDDEEEEDNGNRENIAAQQQLLQQENTNTNNINSPEISSSTIQNDDDLIEEVIEDDGIVEQLIDDDDDEEDDDDDEDEDDEDDDGDDEEGEDDDDEEHQPRRLNFDYSSNYSAKLNGNDGKESVAKSKGQTLLPQQPMLVVRTTSSSRHGGDGEEDDVDDVDDVDEDIFTVGGEAMTIDDIIEEDDGVDEDDVVGVSGGVVEDNDDDDEDEDDDGDDDDDDDNANDDNDDDDDEDDDDDVDHVDGGVNEVVEEDKDDDDAGNEENADVDNSNIGNGVGRVAQDADRDDDSYDTSSSESESTTSQSTGERRNKKKVVASAAHGAAADHSNSSYTCDLCQLCFDSQELLQIHIKSHFLNGPSLGCKKTTTTTTAAVKAAAADAATGFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00511435; iTF_00499025; iTF_00543896; iTF_00500467; iTF_00535481;
90% Identity
-
80% Identity
-