Ddem008622.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila demipolita
Gene Symbol
hang
Assembly
GCA_035042405.1
Location
JAWNLI010000213.1:217387-233023[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.83 58 4.4 3.1 3 23 513 534 512 534 0.93
2 17 1.4 98 3.7 3.5 3 22 641 660 639 660 0.89
3 17 0.00071 0.05 14.0 3.3 1 22 761 782 761 784 0.90
4 17 0.082 5.7 7.5 0.1 2 21 796 815 795 816 0.93
5 17 0.00083 0.058 13.8 0.2 2 23 964 986 963 986 0.95
6 17 0.00028 0.019 15.3 0.2 1 23 994 1017 994 1017 0.97
7 17 0.00018 0.013 15.9 0.2 2 23 1111 1132 1110 1132 0.97
8 17 0.00034 0.024 15.0 2.9 2 23 1248 1270 1247 1270 0.97
9 17 0.027 1.9 9.1 0.2 2 23 1279 1301 1278 1301 0.95
10 17 0.0095 0.66 10.5 0.2 1 22 1314 1335 1314 1337 0.90
11 17 0.00015 0.01 16.2 1.1 1 23 1382 1404 1382 1404 0.99
12 17 0.0023 0.16 12.4 0.9 1 23 1412 1435 1412 1435 0.96
13 17 0.1 7.1 7.2 0.5 2 19 1443 1460 1443 1461 0.95
14 17 0.0012 0.082 13.3 0.3 3 23 1568 1588 1567 1588 0.98
15 17 0.0012 0.087 13.3 0.1 1 23 1623 1645 1623 1645 0.97
16 17 0.0018 0.13 12.7 0.5 2 23 1726 1748 1725 1748 0.92
17 17 0.0042 0.29 11.6 0.3 3 23 1804 1824 1804 1824 0.99

Sequence Information

Coding Sequence
ATGTGCGAcgctgccacaacaacaactgcagcagcagcagcacaaggaACAGGAGTTGCTGGCGACACAGCGATGGAAGAACAAAATCAGCGAGAGCGACAAAGCTGCTGTCGCCTGTGCATTGCGCCCGCCAgcgaatgcatttcaattattaacaGTTATGCGGCCGATAAGGAACCATTGGCCACTAAAATACACAACTGCGTAAATATCAAGatCACATCGGCGGATCGTCTTTCGCTGCATATTTGCCATGCCTGCATCAGTTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCTTCAGCTCACAGACGAAGCATCGCCAATGGCTTGAGAATGACAAAACCAGGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGAGCCGAGAATGGCAACACACTCGAACAAcaccaaaagcagcagcacgaTTTAAAAATGGATTCTGCGACGGCTGCAGCTGAGAAGGCTTCCGCTGTCAACATTTTGGATGGCATACCTCAGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGtccaaagcaacagcagcaagcacatcaacaacagtcgcagcaacatgcgcagcaacagcatgcaACAGTGGCAAGATCAACGCCGAAAAcatcggcggcggcggcagtggCGGAGTCGCCAACAACATTGCAAACCCTTTTATTGCAGGTgcccacaacagcagcagcaggtgcagcagcagcagcgacattAGCAACGGCGTCaacactgcaacagcaacagcagcgcaagcagcaacaccatcagcagcagcaacagcaacgtgGCAAGCAGCATCAACCTCTACAgtatcatcaacagcaacaacagcaacaacagcatcgaCAGAGTCGCATCCGCCAGCCGCGACGACAGCAACAAGCGGCATCGGCCAAATTCAGGAGCCAACTGTTTGTGCCATTGGATATAGCGGTGCCGGCATTGCCAATGCTGTtgccgccaccaccgccagctgttgctgatgcagcGTCGTTGCTAttgccgctgtcgctgccaCTAGATTTCAGTCagaatccgaatccgaatccaaACCCAAATCCCAATCAGTGTCCAAATCCCAGTCAAAATCCAAATCTGAGATTTACAAGTAGCGTTTTagtgccgccgccgccgccgctgcccccagcagttgcaacaatgAGCAGCAGCGAGGCAGCCATTGCCGCTGGCTGtggtgcaactgcaactgcaaccgcaACCGCAGTCACGACTCCATTGCTCATGCCGCCGTTGCCTGCCATGCACATCAAGGATGAGCCCCTGGACGATACGGATGATGACTTTCAAATGAAGTCCGTAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAAGGCGATGTGCCACTAAATACCTCCGACTATGATTATACGGCTCAGCATGGCGTGACCGCTGTTGTGGCAGCGGCATCGTTGCCCGCCAGCGCTGTTGCAAATGTGGCCGCCGCTGGCGACTCCAAGGTGGCCTGCTGCCGGGCGTGCAGTCTGAAGTTCTCGACGCGTGCAAATGCTCGTCGCCACGAGCGCAATCTGCATCCGAATCTGTTCCAATTGTCGACAGACTCACCAAATAATACGCCGATCACAAAACCGACACCGGCATTGGCCGTCGCATTAGAGTTGCAgcgtgcagctgctgcggcggcggcaacCGCTGAGGCAACGCGTGCCGCTGCCGGTGGCAATATATCGACGCAAAAGTATCGCCAGGTGGTGATGAACACGTTCATGAAATGCGAGAACGGCGGCTTCGACTACGACAACCCGGAACAGTATCAGCAGCTGTTGTCCCACGACAAAGTCGACTTTCTACAGGAGAACAGCGAATTTCTCGAACAGTATCAGACGATGACGTGCCGCTGTTGCAGCAAGTTCTTCAACACGTACAAGAACTTCATGGCGCACGTGCGCAAGAAGTATCCGTTGCTGCCACGCAACCTGTGCTTCAATTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCACCTGAAGAAGCGCAACTGCATCAATCTGTATCGTGTGCTCAACGCACTGCGCACCAAACAGCCAAACTTTGTCCATGCCAATGCTTCATCCAGTAGCACTCCAGCTATTGCGGCAGCGGCGACACCACTGCAGCAGTTGGCGACAGCAAGCGAAACACCAGCACCAACATCAACGGATCGTCCGGAAAAGTTGCGTGCCAAGGAGCTGCTGGTTAACAAGCTGTACGAGTGCAAGCTGTGCCCAAAGGGTTTTCGCACCAAGCACGAGTTCCGCACCCATGTCTATGATAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGCTTGGACTTTGCCGATCCGGTGGATCGTCGTAGGCATTACAATAACATGGATTGCATTGTCCGTCTGCGCTGCATGACCTGTGATGCCAAACTGGACACGCATCAGCGCTTTCTCGACCATGTCTATCAGGATCATTTGGGTGGCGTGAGCAGTGATAATGCCCCCTCGACGGTGTCCACCTCTGTCTTGGATCCCTCGTCTGGCAAACGCAAATATAAGGCCGCCTTTGCAATCGGACAATCATCCAACGATGAGTcgcgcaacagcaacagcaacaacaataataataataacagcaacaacaacaacaacaacaataatacatttttaacctCGACACCCACACTAGCAACGGGATCAGGAGCAGGCACAGCTGATGGAGGCGGCACAGCTGGtgcaggtgcaggtgcagCAACCAGTGGCGGGTCAACAACATCGGGCAATCGTGATGCACCCAAATCGCAGTATTTTTCACGAATGCCACAGGTCTGCCCGATCTGTGGCCAGCAgtacaacaactataacaatgTGCTGCGCCACATGGAGTCCAAGCATCCCAACAAATTGCCAGAGACATACAAATGTGTGCGTTGCGGCCGGGGCTATCCACGCATCTCCTATCTGCGGGAGCACATGATCAAGGTGCATGGCGTGGGCAAGAATCGCCATTCGGGCGGCTTTGAGTATATTGTGAATGCCGATGCGGTTAAGCTGGCGGATGGCAGCACACCCAACGTGTATGCGGGTCGATATGATTATGTGATGAAGGATTTGATGTCTATAACAAATGGTGGGACTCTcgatgatgatgacgaagaAGTCGGCGTTGTACAGAGTTGTAAGAAGGTACGATtggacgacagcagcaacaacaacagcaacagcaacaacaacaacaacatgagcaACATTGCCAACCACCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTCAGCAACAATATTGGTCTATCCAATCATATGCGTTCCCATTACACGGCATCGATAACGACAAGTGCTGCTCTGGCGGTGGCCAATCGCATGACGCCCAAATCGCTGACAATAACAGCAACGCCGCCGCTTGAGGTGACAGCCACGGCGACGGCAACATCATCGCTGGCAACGAGCACAGCAAACAACACATCGACTGCTGCTCCAACAaagacaacatcaacaattgtTGCAGCGGTGCCAAcggcaaccacagcagcaaccgGAACAGCAACCACATCATCAGGCGGCAACTTGCCGCCAGCAATGGTGCATCAGACGGCACAGGAGCAGGCGGTATTCCGCCGTAGTCTGGACCAGGCGGCCGATCGACGTTTCCGTCGCATGCGTTGTCGCATCTGTCAGCGCAGATTCAGTTCAAAGAAATCGTATCGCTATCACATGCTGACCGACCACCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCGGAGTTCGCCTACGAGAAGGGGCTCAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATCAAGGACGAGATGATTATCAAGCAATTCGAGTGCGATGTCTGCTCCACCGTCTACAGTTCCGAGCTGGATTTGCAGCGGCACAAGTACGCCGTGCACAACTCACAAGCGACTGAGTCATCATCGAAATCATTGACTGTTACTGCTACCTCCACAACTGACCTGATGGCAGACGCATCAACCTTCATGACGGGCACGCCGGTTGGGGCCCATCTGCTGCCACTCTATTGGTACCAGTGCAAATATTGTCCATCCAACttcaacaccaacaaaaaactgGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGACTACTCCTGCAAGGATTGCGGCAATGTCTACAGCGGCCGCAAGAGCCTTTGGGTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGCCGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATAAGCCCACCTGCAATCGCAAGCCAATCACTGCCACCGGCGCCCATCAGCAggatcagcaacaacaacagatccaacaacagcagcatcacaATCCGCAGAAACATCAGCAGCGGATCATCTTCAAGCACAAAACgggcgatgatgatgacgaggaTGAGGGCGACGATCAGATGCAGCTAATGGATGATGGCGGTAACGGCAGCATTGATAGCATTGCTGACAATGACATTgcatcgacagcagcagcagcagcagcagcagcagccgccgctgcagctgcagcagcagccacattgAAGATACGCATTCCGGGAGTGGCTTGCACCATTTGCGGTGCACGGTTCACCGATCAGGATATATTTACCAAACACATACAGAAGCATGAACAGGAACTGTATGTGGACAATCCGTTGGCGGCCATGTTCGATGATGGGCCAGCGGATGCCGGACAATTTCAGGTTGAGCATCAGAACGAGAATGGCGATTACGCGTGCGATTTGTGCACCAAGACGTTCCCCCAGGTGATAGCACTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGaTTCCAATGCTCGACGGCGAAGCGACAACGctgaacaacagcagcagcagcaacatctacaacaacaacaacaattcgctGAGCTCATCATCGATGCTGCATCTACGCGAACTGCATGCGGTTGGCCTGATGCCCAATCAGCAGGAAcaccagaaacaacaacagctgccgcagcagcagcaagggaCGAGCAAATTAATGAAACGGAAACGTGAACTGAATTGCGAATATTGCGCCTCCACATtcattagcaacaacaacctgAGACGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCGGAGCCGCCAGTGATTGAGGTGGATGAGCCGCTGACGTGTCGCCGTTGCGGCGATCTGCATTTTGATACCAAAGAGCAATGGATCGAACATAAGCTGGCCGATGCCAGAGTGGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTCTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAGTCATCTTAAGGAGGATGTGATTGTGCCCGTCGCCAGCAAGCTACCAGCAACGGCAGTCAACAACACCGtaaaaaaatcagcagcagcagcagcagcagcagcaacaacaacagctgccgcagcaaatgttgcaaatgaTCCATcagcaagtgcagcagcagcaacagcaacagcagcaacaaaagaacTTAAGGCTAAGCAACACCACCTGCGGGAACAGGCAGAAGATGAGGACGATGTGAAGCTAAGGAAGCAGCAGGAAGAAGATGATAGTGATATGAATGATGAAAGCGAGAGTGGCAATGATGATGAggagggcagcagcagcagcagtgctgatgacgatgatgaagataatgatgacgacgatgaagatgatgatgacgacgacgatgacgacgacgacgacgacgaagaagaagacaacGGCAATCGCGAAAATATTGTcgcacagcagcaattgctgcagcaacaaaatacaaacaccaacaacatcaactcccccgaaatcagcagcagcacaattcATAATGCCAATGATCTTTTCGAGGAGGTAATCGAAGATGATGGCATTGTCGAGCAGCTGatcgacgatgatgatgatgaagaagatgatgatgatgatgatgaggatgaggatgaggatgatgaggacgacgatgatgacgatgaggagGGGGAGGATGATGATAATGAGCAACACCAGCCAAGACGCCTCAATTTCGATTACTCAAGCAATTACAGCGCCAAGCTAAATGGCAACGATGGCAAACAGTCTGTGGCAAAATCAAAGGGGCAGACACGTTTGCCGCAACAGCCAATGCTGGTCATGCGCACCACAAGTCGTAGTAGTCGCCACGGACGAGATGGCGAGGAGAACGATGTGGATGATGTGGACGATGTGGATGATATCTTTACAGTTGGCGGTGAGGCGATGACTATTGATGATATTATTGAAGAGGATGATGGTGTGGATGAAGACGATGTGGTTGGTGTCAGTGGTGGTGTTGTTGaggataatgatgatgatgatgacaaggacgacgacgacgacgacgatgacgacgatgacgacgacgatgacgacgatgacgacgacgatggcgatgATGCTAATGTTgacgatgatgaagatgatgatgttgatgatgttgacgGTGGTGGTAATGACGTTGAAGAGGAGGACAAAGATGATTATTATGccagcaacaagaagaatGCCGATGTCGACAACTCCAACATTGGCAACGGTGTTGGACGTGTGGCTCAAGAtgctgatggtgatgatgatagTTATGATACATCATCATCTGAGAGCGAGTCGACCACATCACAATCATCTGGAACTTCTTCAGATTCATATCAAAAGTCATTTCCTCAATGGGCCGTCGGTGGGGAGCAGCAACCCCAGcggcaagagcaacaacaacagcaataa
Protein Sequence
MCDAATTTTAAAAAQGTGVAGDTAMEEQNQRERQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITSADRLSLHICHACISYLNSWQSFKNRCFSSQTKHRQWLENDKTRQQTLLGYLDLNRAENGNTLEQHQKQQHDLKMDSATAAAEKASAVNILDGIPQLKKRKSLTVYVSPKQQQQAHQQQSQQHAQQQHATVARSTPKTSAAAAVAESPTTLQTLLLQVPTTAAAGAAAAATLATASTLQQQQQRKQQHHQQQQQQRGKQHQPLQYHQQQQQQQQHRQSRIRQPRRQQQAASAKFRSQLFVPLDIAVPALPMLLPPPPPAVADAASLLLPLSLPLDFSQNPNPNPNPNPNQCPNPSQNPNLRFTSSVLVPPPPPLPPAVATMSSSEAAIAAGCGATATATATAVTTPLLMPPLPAMHIKDEPLDDTDDDFQMKSVDESDDMMDPTMFLERSEHEGDVPLNTSDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVACCRACSLKFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAVALELQRAAAAAAATAEATRAAAGGNISTQKYRQVVMNTFMKCENGGFDYDNPEQYQQLLSHDKVDFLQENSEFLEQYQTMTCRCCSKFFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRTKQPNFVHANASSSSTPAIAAAATPLQQLATASETPAPTSTDRPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLDTHQRFLDHVYQDHLGGVSSDNAPSTVSTSVLDPSSGKRKYKAAFAIGQSSNDESRNSNSNNNNNNNSNNNNNNNNTFLTSTPTLATGSGAGTADGGGTAGAGAGAATSGGSTTSGNRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGRGYPRISYLREHMIKVHGVGKNRHSGGFEYIVNADAVKLADGSTPNVYAGRYDYVMKDLMSITNGGTLDDDDEEVGVVQSCKKVRLDDSSNNNSNSNNNNNMSNIANHQKECLICNAVFSNNIGLSNHMRSHYTASITTSAALAVANRMTPKSLTITATPPLEVTATATATSSLATSTANNTSTAAPTKTTSTIVAAVPTATTAATGTATTSSGGNLPPAMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSELDLQRHKYAVHNSQATESSSKSLTVTATSTTDLMADASTFMTGTPVGAHLLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHKPTCNRKPITATGAHQQDQQQQQIQQQQHHNPQKHQQRIIFKHKTGDDDDEDEGDDQMQLMDDGGNGSIDSIADNDIASTAAAAAAAAAAAAAAAAATLKIRIPGVACTICGARFTDQDIFTKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVEHQNENGDYACDLCTKTFPQVIALKVHRKWHFRGDSKQIPMLDGEATTLNNSSSSNIYNNNNNSLSSSSMLHLRELHAVGLMPNQQEHQKQQQLPQQQQGTSKLMKRKRELNCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDLHFDTKEQWIEHKLADARVVRPFCPFQWGCDLCGEYLSRKEKLINHINSHLKEDVIVPVASKLPATAVNNTVKKSAAAAAAAATTTAAAANVANDPSASAAAATATAATKELKAKQHHLREQAEDEDDVKLRKQQEEDDSDMNDESESGNDDEEGSSSSSADDDDEDNDDDDEDDDDDDDDDDDDDEEEDNGNRENIVAQQQLLQQQNTNTNNINSPEISSSTIHNANDLFEEVIEDDGIVEQLIDDDDDEEDDDDDDEDEDEDDEDDDDDDEEGEDDDNEQHQPRRLNFDYSSNYSAKLNGNDGKQSVAKSKGQTRLPQQPMLVMRTTSRSSRHGRDGEENDVDDVDDVDDIFTVGGEAMTIDDIIEEDDGVDEDDVVGVSGGVVEDNDDDDDKDDDDDDDDDDDDDDDDDDDDDGDDANVDDDEDDDVDDVDGGGNDVEEEDKDDYYASNKKNADVDNSNIGNGVGRVAQDADGDDDSYDTSSSESESTTSQSSGTSSDSYQKSFPQWAVGGEQQPQRQEQQQQQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00552463;
90% Identity
-
80% Identity
-