Dlon003989.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila longiperda
Gene Symbol
hang
Assembly
GCA_035042125.1
Location
JAWNLV010000105.1:634222-649805[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.37 25 5.6 1.0 3 23 515 536 514 536 0.93
2 17 1.1 71 4.1 3.2 3 22 643 662 641 662 0.89
3 17 0.0033 0.22 12.0 2.6 1 23 771 794 771 794 0.91
4 17 0.053 3.6 8.2 0.1 2 21 806 825 805 826 0.93
5 17 0.00092 0.062 13.8 0.2 2 23 969 991 968 991 0.95
6 17 0.0026 0.18 12.3 0.1 1 23 999 1022 999 1022 0.96
7 17 3.5e-05 0.0024 18.2 0.9 2 23 1114 1135 1113 1135 0.97
8 17 0.00038 0.025 15.0 2.9 2 23 1250 1272 1249 1272 0.97
9 17 0.03 2 9.0 0.2 2 23 1281 1303 1280 1303 0.95
10 17 0.034 2.3 8.8 0.2 1 22 1316 1337 1316 1339 0.90
11 17 0.00016 0.011 16.1 1.1 1 23 1399 1421 1399 1421 0.99
12 17 0.0026 0.17 12.4 0.9 1 23 1429 1452 1429 1452 0.96
13 17 0.0031 0.21 12.1 0.1 3 23 1564 1584 1563 1584 0.98
14 17 0.0018 0.12 12.8 0.1 1 23 1619 1641 1619 1641 0.97
15 17 0.26 18 6.0 1.9 2 23 1748 1770 1747 1770 0.88
16 17 0.0028 0.19 12.2 0.2 3 23 1826 1846 1826 1846 0.99
17 17 0.00057 0.038 14.4 2.7 1 23 2271 2293 2271 2293 0.99

Sequence Information

Coding Sequence
ATGTGCGAcgctgccacaacaacaacagcagcagcagcacaaggaACAGGAGCTGCTGGCGATACAGCGatggaagaaaaaaatcagCGAGAGCGACAAAGCTGCTGTCGCCTGTGCATTGCGCCCGCCAGCGAatccatttcaattattaacaGTTATGCGGCCGATAAGGAGCCATTGGCCACTAAAATACACAACTGCGTAAATATCAAGatcacATCGACGGATCGTCTTTCGCTTAATATTTGCCATGCCTGCATCAGCTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCTTCAGCTCACAGGCGAAGCAGCGCCAATGGCTTGAGAATGATAAAACCAGGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGAGCCGAGAATGGCAACACAGTtgagcaacaccaacagcagcagtacgATTTGACAATGGATTCGGTGACGTCTGCAGCTGAGAAGGCTTCCGCTGTCAACATTTTGGATGGCATACCTCAGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGtccaaagcaacagcagcaagcacagcaacaacagtcgcagcaacatgtgcagcaacagcatgcAACAGTGGCAAGATCAACATCGAAAAcattggcggcggcggcagtggCGGAgtcgccaacaacaacattgcaaACCCTTTTATTGCAGGTgcccacaacagcagcagcagcgacagcgacttTGGCAACGGCGTCaacactgcagcagcaacagcagcgcaagcagcaacagcatcatcatcagcagcaacgtggcaagcagcagcaccaacatcTACAGTATcataaacagcagcaacagcatcgacAGAGTCGCATCCGCCAGCCGCGACGACAGCAACAAGCGGCATCGGCCAAATTCAGGAGCAAACTGTTTGTGCCATTGGATATATCGGTGCCGGCACTGCCGGCATTGCCAGCGCTGTtgccgccaccaccgccagctgttgctgatgcagcGTCGTTGCTATTGCCTCTGTCGCTGCCACTTGATTTCAGTCagaatccgaatccgaattCAAACCCAAATCCCAATCAGTATCCAAAACCTAGTCAAAATCCAAATCAGATATTTACAAGTAGCGTTTTagtgccgccgccgccgccaccgctgccgctgccgctgccccCGGCAGTTGCAACAATGAGCAGCAGCGAGGCAGCCATTGCCACTGGCTGtggtgcaactgcaactgcaactgcaaccgcAACCGCAGTCACGACTCCATTGCTCATGCCGCCATTGCCTGTCATGCCCATCAAGGATGAGCCCATGGACGATACGGATGATGACTATCAAATAAGGAGTACAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTTCGAGCATGAAGGCGATGTAAATGCCTCCGACTATGATTATACGGCTCAGCATGGCGTGACCGCTGTTGTGGCAGCGGCATCGTTGCCCGCCAGCGCTGTTGCAAATGTGGCCGCCGCTGGTGACTCCAAGGTGGCCAGCTGCCGGGCGTGCAGTCTGCAGTTCTCGACGCGTGCAAATGCTCGTCGCCACGAGCGCAATCTGCATCCGAATCTGTTCCAATTGTCGACTGACTCACCAAATAATACGCCGATCACAAAACCGACTCCGGCTTTGGCCGCCGCATTGGAGTTGCAGCGTGCAGCTGTTGCGGCGGCGGCAACCGCTGAGGCAACGCGTGCCGCTGCCGGTGGCAATATATCGGCCCAAAAGTATCGCCAGGTGGTGATGAACACGTTCATGAAATGCGAGAACGGCGGCTTCGACTACGACAACCCGGAACAGTATCAGCATCTGTTGTCCCACGACAAAGTTGACTTCTTGCAGGAGAACAGCGAATTTCTCGAACAGTACCAGACGATGACGTGCCGCTGTTGCAACAAGTACTTCAACACGTACAAGAACTTCATGGCCCACGTGCGCAAGAAGTATCCGTTGCTGCCACGCAACCTGTGCTTCAATTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCACCTGAAGAAGCGCAACTGCATCAATCTATATCGTATGCTGAACGCACTGCGCACCAAACAGCCAAACTTTGTCCATGCCAATGCTTCATCCAGTAGCACTCCAGCTATTGCGGCAGCGGCGACAGCAAGCCgtacaccagcaacagcaacaacatctgcaacaggaacaggaactcCTGGAACAGCAAAAACATCAACGGATCCTCCAGAAAAGTTGCGTGCCAAGGAGATGCTGCTTAACAAACTGTACGAGTGCAAGCTGTGCCCAATGGGTTTTCGCACCAAGCACGAGTTCCGCACCCATGTCTATGAAAAGCATGCGGATGTGCAGCGCAAGGATAACAGTTCGATACAGTGCAGCTTCTGTGGCATGGACTTTGCCAATCCGGTGGATCGTCGTAGGCATTACAATAATATGGATTGCATTGTCCGTCTGCGCTGCATGACCTGTGAAGCCAAATTGGATTCGCATCAGCGCTTCCTCAAACATGTCTATCAGGATCATTTAGGTGGCGCGAGCAGTGATAATGCCTCCTCGACGGTGACCACCACCTCTGTCTTGGAACAATCGGCTGTCAAACGCGGCTTTCTGGCCAACTTTGGATTCGGTCAATCATCCAACGATGAGtcccgcagcagcaacagcaacaacaataataacaataacagcaacaaaaataataataataatacactttTAACCCCGGCATCCAAACTACCAACGGGATCTGGTGCAGGCACAGCTGGTGGAGGCGCAGCAGGTGTAACAACCAGTGGCGGCTCAACAACATCGGTCAGTCGTGATGCACCCAAATCGCAGTATTTTTCACGAATGCCACAGGTTTGTCCGATCTGTGGCCAGCAgtacaacaactataacaatgTGCTGCGCCACATGGAGTCCAAGCATCCCAACAAATTGCCAGAGACATACAAATGTGTGCGTTGCGGACTGGGCTATCCACGCATCTCCTATCTGCGGGAGCACATGATCAATGTGCATGGCGTGGACAAGAATCGCCATTCGGGCGGCTTTGAGTATATTGTGAATGCTGATGCGGTTAAGCTGGCGGATGGCAGCACACCCAATGTGTATACGGGTCGATATGATTATGTGATGAAGGATTTGATGTCTATAACAAATGGTGGGACTCTcgatgatgatgacgaagaACTCGGTGTTTTACCTAAGAAGATACGATTGGAcgacagctgcaacaacagcagcagcaacaacaacaacaacaacttgagcAACATTGCCAACCAGCAGAAGGAGTGCCACATCTGCAATGCGGTGTTCAGCAACAATATTGGTCTATCCAATCATATGCGTTCCCATTACACGGCATCGATAACATCGACAAGTGCTGCTCTGGCGGCAGCCAATCGCATGACGCCCAAATCGCTGACAATAACAGCAACGCCGCCGCTTGAGGTgacagcgacggcgacggtAACATTACCGCTGGCAACGAGCACAGCAAACAACACATGGACTGATTCTTTAACAACTGTTGCATCAAAGCCAACAGCAACCGGAACAGCATCTACATCATcaagcggcggcggcggcggcagcggcggcaactTGCCGCCAGCAATGGTGCATCAGACGGCACAGGAGCAGGCGGTATTCCGCCGTAGTCTCGACCAGGCGGCCGATCGACGTTTCCGTCGCATGCGTTGTCGCATCTGTCAGCGCAGATTCAGTTCAAAGAAATCGTATCGCTATCACATGCTGACCGACCACCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAACGCGGAGTTTGCCTACGAGAAGGGGCTCAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATAAAGGACGAGATGATTATCAAGCAATTCGAGTGCGATGTCTGCTCCACCGTCTACAGTTCCGAGCTGGAATTGCAGCAACACAAGTACGCCGTGCACAAGTCACATGCGAGtgagtcatcatcatcatcagcagcaacagcaacagcagcagctagtgGCAAACATTCATCATCGAAATCATTGAATGCTACTGCTACCACCACATCTGACCTAGACACATCAACCTCCATGACGGGCACGCCGGGTGCGGCCCATCTGCTGCCACTCTATTGGTACCAGTGCAAATATTGTCCATCCAACTTCAACACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAAAGATTACTCCTGCAAGGATTGCGGCAATGTCTACAGCGGCCGCAAGAGCCTCTGGGTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGCCGAGTGCACGCTGTGCTGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATAAGCCCACCTGCAATCGCAAGCCAATCACTGCCACCGGCGCCCATCAGCAGGatcaagagcaacagcagcatcaacatcagcagcaatatcAAAAGCGGCTCATCTTCAAGCACAAAACGggcgatgatgacgacgaggaTGAGGACGACGATCAGATGCAGCTAATGGATGATGGCTGCGGCAGCAATGCGATTGcatcgacagcagcagcagctgcagctgcagccacaTTGAAGATACGCATTCCGGGTGTGGCATGCACCATTTGCGGTGCACGTTTCACCGATCAGGATATATTTGCCAAACATATACAGAAACATGAACAGGAACTGTATGTGGACAATCCGTTGGCGGCCATGTTCGATGATGGGCCAGCGGATGCCGGACAATTTTGGGTTGAGCATCAGAACGAGAATGGCGAATACGCGTGCGATTTGTGCACCAAGACGTTCCCCCAGGTGATAGCACTCAAGGTGCATCGCAATTGGCATTTCAGAGGTGATAGCAAGCAGaCTCCAATGCTCGACGGCGAAGCGACAACGctgaacaacagcagcaacaacagcagcaacagcaacatctacaacaacagcagcaacagcaacaactacaacaacagcagcaacatctacaacaacaacaacaacaacaacaattcactGAGCTCATCATCGATGCTGCATCTACGCGAACTGCATGCAGTTGGCCTGATGCccaatcagcagcaacaccaaaaacaacaacagcaacaacagctgccgcaGAAGCAGCAACGGACGAGCAAATCAATGAAACGGAAACGTGAACTAAAATGTGAATGTTGCGCCTCCACAttcattagcaacaacaatctgaGACGCCACATGTACGAGCTGCACAAGCACGAGGTGAGCAATCTGCCGGAGCCGCCAGTGATTGAGGTGGATGAGCTGATGTCCTGTCGCCGTTGCGGCGATCTGCAGTTTGATACCTTAGAGCAATGGATCGAACATAAGCTGGCCGATGCCAGAGTGGTGCGCCCATTCTGCCCATTCCAATGGGGATGTGATATCTGCGGCGAGTACTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGAATGTGATTGTGCCCGttaccagcaacaacaccgtaaaaaaatcagcagcagcagcagcagcaggaaaaacaacaacaacaacaacttttgctgCCGCATCAAAAGTTGCAAATGCTACAAcaccaaaagcagcagcagcaacagcaacaaaagaacTTAAGGCTAAGAAACACCACCTGCGGGAACAGGCAGAAGATGAGGACGATGTGAAGCAGCAAACGAAGCAGCAGGAAGATGATGATAGTGATATGAATGATGATAACGAGAGTGGCAATGATGATGAGgagggcaacagcagcagcagttctgATGATATTGATAATGACGACGATGaggataatgatgatgatgatgatgaaggcgacgacgacgacgaagaagaagatgaagaagacaACGGCAATGGCGAAAAAACACCAAACACCAACCACAACAATTCCGCCGACAGCATCAACAACCCAATTCATAATGACAATGATCTCATCGAGGAGGTAATCGAGGATGATAGCATTGTCGACGTGGtggacgacgacgatgatgaagaagatgatgatgacgatgaggaggacgatgatgacgatgaggaggGCGAGGAGGAGGACGAAGAGCAACGCCCGTCAAACCCCCTCAATTACAACTTCGCAAGCAGTTACGGCGCCAAGCAAAATGGCAACGATGGCAAACGGTCTGTGGCAACATCAGAGACGCAGAGACATTTGTCGCTAGACTCAATGATGCTCATGGATAGGGATTTAAGTCGCCGCAGACGAGATAGCCACGAGGTGGATGAGGATGGTTATACAGTTAGCGGTGAAGAGATGAATATTGATGATATTATTGAAGAGGATGATGGTGTGGATGAAGACGATGAGGTTGGTGTCGGTAGTTATGTTGTTAaggataatgataatgatgatgacgacgacgacggcgacaacgacaacgacgacggcgacgacgacgacgacgacgatgacgaccgCGACGActatgacgacgatgatgctaatgatgatgatgatgaagattgtgatgatgataatgatggtGGTAATGAAGTTAAAGAGGATGACAAAGATGATGACGGCAGCAAGGGCAGTGCCGTTGTCGACCACTCCAACATTGGCAACGGTGTTGGACGTGTGGCTCAAGaatctgatgatgatgatgatagtGATGATTCATCATCATCTGGGAGCGAGTCGACAACATCACAATCAACTGCGGCACATGGTGCTGCCGGTGATCAGTCTAATTCCAGTTATACGTGTGATCTATGTCAACTTTGTTTTGATTCCCAGGAGCGTCTTCAAACTCATATTAAAAGTCATTTCCTCAATGGGCCGTCGGTTGGGAGCATCAGCCACGGCAGCAAGAGCAACGgtcccagcaacagcagcagcagcagcagcagcaacagcaacagcagcagcagcaaaagtagcagcggcagcagcagcaacagcagcagcaacagcaataacaaaatcaatacCAAAAAGTCCAGCTTGGATGCAACGaagacaacaaccacaacagcagctgcagcagcctaTGCTGCAACGGGCTTCAACTGA
Protein Sequence
MCDAATTTTAAAAQGTGAAGDTAMEEKNQRERQSCCRLCIAPASESISIINSYAADKEPLATKIHNCVNIKITSTDRLSLNICHACISYLNSWQSFKNRCFSSQAKQRQWLENDKTRQQTLLGYLDLNRAENGNTVEQHQQQQYDLTMDSVTSAAEKASAVNILDGIPQLKKRKSLTVYVSPKQQQQAQQQQSQQHVQQQHATVARSTSKTLAAAAVAESPTTTLQTLLLQVPTTAAAATATLATASTLQQQQQRKQQQHHHQQQRGKQQHQHLQYHKQQQQHRQSRIRQPRRQQQAASAKFRSKLFVPLDISVPALPALPALLPPPPPAVADAASLLLPLSLPLDFSQNPNPNSNPNPNQYPKPSQNPNQIFTSSVLVPPPPPPLPLPLPPAVATMSSSEAAIATGCGATATATATATAVTTPLLMPPLPVMPIKDEPMDDTDDDYQIRSTDESDDMMDPTMFLERFEHEGDVNASDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALELQRAAVAAAATAEATRAAAGGNISAQKYRQVVMNTFMKCENGGFDYDNPEQYQHLLSHDKVDFLQENSEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRMLNALRTKQPNFVHANASSSSTPAIAAAATASRTPATATTSATGTGTPGTAKTSTDPPEKLRAKEMLLNKLYECKLCPMGFRTKHEFRTHVYEKHADVQRKDNSSIQCSFCGMDFANPVDRRRHYNNMDCIVRLRCMTCEAKLDSHQRFLKHVYQDHLGGASSDNASSTVTTTSVLEQSAVKRGFLANFGFGQSSNDESRSSNSNNNNNNNSNKNNNNNTLLTPASKLPTGSGAGTAGGGAAGVTTSGGSTTSVSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDEELGVLPKKIRLDDSCNNSSSNNNNNNLSNIANQQKECHICNAVFSNNIGLSNHMRSHYTASITSTSAALAAANRMTPKSLTITATPPLEVTATATVTLPLATSTANNTWTDSLTTVASKPTATGTASTSSSGGGGGSGGNLPPAMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSELELQQHKYAVHKSHASESSSSSAATATAAASGKHSSSKSLNATATTTSDLDTSTSMTGTPGAAHLLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSKDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCCKMFFDRQMLENHKPTCNRKPITATGAHQQDQEQQQHQHQQQYQKRLIFKHKTGDDDDEDEDDDQMQLMDDGCGSNAIASTAAAAAAAATLKIRIPGVACTICGARFTDQDIFAKHIQKHEQELYVDNPLAAMFDDGPADAGQFWVEHQNENGEYACDLCTKTFPQVIALKVHRNWHFRGDSKQTPMLDGEATTLNNSSNNSSNSNIYNNSSNSNNYNNSSNIYNNNNNNNNSLSSSSMLHLRELHAVGLMPNQQQHQKQQQQQQLPQKQQRTSKSMKRKRELKCECCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDELMSCRRCGDLQFDTLEQWIEHKLADARVVRPFCPFQWGCDICGEYLSRKEKLINHINNHLKENVIVPVTSNNTVKKSAAAAAAGKTTTTTTFAAASKVANATTPKAAAATATKELKAKKHHLREQAEDEDDVKQQTKQQEDDDSDMNDDNESGNDDEEGNSSSSSDDIDNDDDEDNDDDDDEGDDDDEEEDEEDNGNGEKTPNTNHNNSADSINNPIHNDNDLIEEVIEDDSIVDVVDDDDDEEDDDDDEEDDDDDEEGEEEDEEQRPSNPLNYNFASSYGAKQNGNDGKRSVATSETQRHLSLDSMMLMDRDLSRRRRDSHEVDEDGYTVSGEEMNIDDIIEEDDGVDEDDEVGVGSYVVKDNDNDDDDDDGDNDNDDGDDDDDDDDDRDDYDDDDANDDDDEDCDDDNDGGNEVKEDDKDDDGSKGSAVVDHSNIGNGVGRVAQESDDDDDSDDSSSSGSESTTSQSTAAHGAAGDQSNSSYTCDLCQLCFDSQERLQTHIKSHFLNGPSVGSISHGSKSNGPSNSSSSSSSNSNSSSSKSSSGSSSNSSSNSNNKINTKKSSLDATKTTTTTAAAAAYAATGFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00552463;
90% Identity
-
80% Identity
-