Basic Information

Insect: Drosophila multiciliata
Gene Symbol: zfh1
Assembly: GCA_037043605.1
Location: JBAMBF010000344.1:774059-779842[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.8e-05 0.0019 18.5 1.0 1 23 152 174 152 174 0.97

2 15 0.00086 0.057 13.8 1.2 3 23 182 202 180 202 0.94

3 15 9.3e-05 0.0062 16.9 0.1 1 23 386 408 386 408 0.98

4 15 0.00032 0.022 15.2 0.9 1 23 414 436 414 436 0.98

5 15 0.0023 0.15 12.5 4.3 1 20 468 487 468 491 0.89

6 15 0.0086 0.58 10.7 3.0 1 23 540 562 540 562 0.94

7 15 0.009 0.6 10.6 0.4 1 23 568 591 568 591 0.97

8 15 0.027 1.8 9.1 0.4 3 19 600 616 599 617 0.95

9 15 0.00016 0.011 16.1 5.7 1 23 626 648 626 648 0.97

10 15 0.042 2.8 8.5 1.2 2 23 654 675 653 675 0.96

11 15 9.5e-06 0.00064 20.0 1.0 1 23 684 706 684 706 0.98

12 15 0.0011 0.072 13.5 0.1 3 23 714 734 712 734 0.97

13 15 5.8e-05 0.0039 17.5 0.5 1 23 740 762 740 763 0.95

14 15 0.049 3.3 8.3 0.4 1 23 773 795 773 795 0.97

15 15 0.0016 0.11 13.0 0.4 1 23 1312 1334 1312 1334 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.8e-05	0.0019	18.5	1.0	1	23	152	174	152	174	0.97
2	15	0.00086	0.057	13.8	1.2	3	23	182	202	180	202	0.94
3	15	9.3e-05	0.0062	16.9	0.1	1	23	386	408	386	408	0.98
4	15	0.00032	0.022	15.2	0.9	1	23	414	436	414	436	0.98
5	15	0.0023	0.15	12.5	4.3	1	20	468	487	468	491	0.89
6	15	0.0086	0.58	10.7	3.0	1	23	540	562	540	562	0.94
7	15	0.009	0.6	10.6	0.4	1	23	568	591	568	591	0.97
8	15	0.027	1.8	9.1	0.4	3	19	600	616	599	617	0.95
9	15	0.00016	0.011	16.1	5.7	1	23	626	648	626	648	0.97
10	15	0.042	2.8	8.5	1.2	2	23	654	675	653	675	0.96
11	15	9.5e-06	0.00064	20.0	1.0	1	23	684	706	684	706	0.98
12	15	0.0011	0.072	13.5	0.1	3	23	714	734	712	734	0.97
13	15	5.8e-05	0.0039	17.5	0.5	1	23	740	762	740	763	0.95
14	15	0.049	3.3	8.3	0.4	1	23	773	795	773	795	0.97
15	15	0.0016	0.11	13.0	0.4	1	23	1312	1334	1312	1334	0.98

Sequence Information

Coding Sequence: ATGAACAATCCGGACTATGGCGGCATCCAGTGGATACAGCAGGAAAGCAGCGCCGTCGCCGACGACAGCGAAACAGAGATGACAGCAGCCTATTTGGTCAACGCTGCCGCCAATGGAAGCATTTCCAACGATGACGATCTCGATCATATGGCAGCCGAGAATCTCATCTTTATGGCACGCGACGGCCAACTGAGCGAAATTATCGCCGCCAATGAGGCAAatggcggcagcagcacagTGCTAATCACGGAAAGCGACGGAAATAACGGTGTGGAATACGCCGAATCCTTTGACGACGATACCCAAGTCGTCACAGAGGAGATCATCACGGATGATTGGGTCCAGCATCAGGGCGCAGAGCGtgTGGAAATTGCGGCGGAACAAATCGCTGGCAATGGCAGCTCGCAGGAGCTGTTGGACATGCAACAGAATGAATATATGGCGATGCGTCCCTATCCCTGTGACTTTTGCAGTCGACGCTTTCGGAAGAAGGCCAGCCTCAACAATCACATGCTGGCGCATCAGAATGATCGTCCCCATCTCTGCAAGCTGTGCGGAGCGCGTTTCTCGCGACGGGCAGAGCTCATCAGTCACTTCAAGGCGCATGCGGAGGCCCAGGTGGCCGCCGATGAAGAGGCAGCTGCGGCAGCCATTAAATTTGAGCCActacagcagctgcaacaccatcagcagcagcagcagcagcagcgacaaatTGAGGATCATTTCTATGAGCACGAATGGCCGCTGTAtcaggaacaggagcaggaacCAGAGCAAGAGCATGAGCCGGGGCGGGAGCAGGTCGAAGAGCAGCTGGAGCAAattgaggagcagcagcagctggagcagcatcagcagctggagcagcatcagcagctgaTGCAACAATCGGTGGCACCACCCACCGCTGCTCGTGGACGCATCAGTCGCTTGAAGCTCAAAGAGGAACAATATATTGTGATTGCCCCCGATAAACCGGAGACGGAGTTGCCTCAATACATGCATTGTGATGCGAATTGCGATCAATCACttgccaccaacaacaacaacaacaaccaactcCAAGCAACGCCATCCAATGATTTTGCAACTGCTGATGGGGCACAGAGGCAGGCAACGTTGCGTTTTCCCGTGCTCGATGAGAGCAAACCATTTGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCTCTCGTCTCCCACATCAAGAATCATCGCGTGGATTCGCCGTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAATTATAGTTTGCAGGAGCATCAGAAAACACATCAATTCGAGGAGAGCAACTCGGAATACGATCCCGCATCGGCGGGCGAGGAGGATACGGCGAGTGAATCGGAAGCGGAACAGCTTTACGGTGATTTTTACTGCGGCGAATGCGGCATCTCCTTTCACCGGCAGGATTTGTTGCGGCGCCACTGCAAACAGCAGCACAGCAAGCACctaactgcaacaacagctgtgggcaacaacaacagtgtggcaactgcaacagcaacggatgcagtgtgtgtggcagctgcaggTGCAACTGATgccgatgctgatgctgatgctgatgatgccaAAGATGCGCCACATTGTTGCCACACCTGTGGCAAATCATTTCCCAACGTACTCAAACTGCTCGCCCATGCCGAAATCCACAAACGTTTCCCGCCATTCAAATGTGTCCTGTGCGGAGTCAGCTTCTACGAGGAGCAGGCCATCAAGCGGCACCTGAGCACGCGGCATCCGCACGAGCTGAAGCAGAACtcgtgtgtgttgtgtggcaaGGAGTGCCGGGATCGGAAGGCGCTGATCAAGCATGCGTGGGATCATTCGCGGGAGAAGTGCCACTCGTGCTCCAAGTGTGGTAAGAATTTCCACAACAAGGGGCGCCTGAAGCGGCACATGGCATCGCATCGCGACAAGTCCGTCGTGTGTGAAGTGTGCCACGAAGAGTTCCCCGACGGACGCACTTTGTCCAACCATCGGCATTCCCACAGCACAACGTCGCCGGGCAAAATGTTTCCTTGCCACGAGTGTGGCAAGACCTTTGGGTCGCGCAGCTCGCAGCAGATTCACGTGCGCATCCACACGGGTGAAAGGCCCTACGGTTGTCGGTACTGCTGGAAGGCCTTCGCCGATGGCGGCACTCTCCGCAAACACGAGCGCATCCACACCGGCGAGAAGCCCTACGCCTGCTCCGTCTGTCCGCGTGCCTTCAATCAGCGTGTCGTCCTGCGGGAACACATCCGATCACATCATTCGGGTCTGGATGTGGCACTTGGCACGTATCATTGCACGGTCTGCTCGGCGGATTTGAGCTCATCAAATGACCTCATCCAGCATCTCATCCAGCACAGTGATACGAACACAGCCAAACAGCGACAGCCAATTACTGGTCCACGTAAATACAAACGTCGCCGGAAACTGCAGCCGCATGAAATTGCGCATATGCGCGCCGAGCACAAGGCTGGCGGCGTCGATGGCGAGGttggggaggaggaggattaTGTGAGCGACTTGGACTACTGCGATCTGGATGTGGAGAATGTGGATGAGTTGCTGCAGGAAGCAACCGCAgagccgccaccaccacccgccaaaaaagcaaaacgcaAACGCAAAGCTCCAATTAAATCAGGAGATGAGCAAAGATTGTGGGATGAGAAATTCCTGCAGCAGACGAGCAATGGAAACAGCGATGAGGCCTACAAAAGTTTCTTTCAAATGGATTCGCTGGTGGTGGTCAATGATCAAACGTTGCAGCCAGTTGATGCTGCCAAGCTGCAGCAGGCTGAGATTAAGGAGCAAAAACTGAAAGCaggcagtcgcagcagcaaaagaaggGCTGCAAAAGCTGgcggaggagcaggagcagcaggcggaggagcagcaggagcaggtggaggtggagctgctgctgctccacgtCCACGCATGATACATACGGCCAAGTCGCAGCAGACAACTTCAAAGAAATCCCGCACAAGGAGTTATATCACACGCACCAGCAccaatgagcagcagcagcagcagggaagaggaggaggagcaactGGAGGAAGCCTTATCAAATCGCGCATTGTGGATGACTATGAGATCATCTCACCGGCCACACAGCCACCCAATCAAATCAGCTCCAGTCCACTGCACATCaaacaggagcaggaacatcatcatcatcatcatcatcatcagcagcatcagcagcatcatcatcagcagcagcaacgagctCAGCTGCTCTTTGATGACAGCCATCTGCTCATCGATGCGGGCCTGTTGCGTGAGAAGACCTACGAGAAATATAACCCCAGCATTGTTCAAGATCTCGAGGAGATTTTGCGTAGTCCCCCCAAGCATGAGCGGGACGATCGACGGCTGCGCTTCACCAGCGAATCGTCGACGACGCCACAATTTCTGCCCGGTGAGGAGGAGGAACAGCATCTCATCAAGATCGAGCCAACGTCGCCGGATCTCCGCGAAATGGTCGAGAGCCAGCAGCCAGCTACACTGCCAGCGTCCTCCTCCGTCGGTTCAACGGCGGCACGCACTTCCCGCCACCTGCGTCAGCTGACTGCAAAAGGTTCCGGCTCCGGTTCCATTTTGACTGCCACTTCTAGTTCCAGTGCTACTACCAGCACGCGATCCGCTTCCAAGCGCAATGCCAGCAAACAGCTTTCCAAGAAATCCActtccaacagcaacaagggcAACTCATCATCTTCTTATCTCAACTACGGCGTCGACTCTTACCATGTGGGCGTGGTGGCCAGTGCCACAAGCTCCTCGGATGTCAGTTCCGGTTTCTTTTCCATCTCCGAGGTCGTCTCGGCGGCAGATGCAGCGGATGCAGCTGCAaaggcggcggcagcagccagcaaaacGGAGCGAAAAACGCGTTGTTTTGAGTGCGAAATGTGCTCGTCCAATTTTCCAGATCGTGCCCAGCTGCTGgaacacatgcatatacacatCTAG
Protein Sequence: MNNPDYGGIQWIQQESSAVADDSETEMTAAYLVNAAANGSISNDDDLDHMAAENLIFMARDGQLSEIIAANEANGGSSTVLITESDGNNGVEYAESFDDDTQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQVAADEEAAAAAIKFEPLQQLQHHQQQQQQQRQIEDHFYEHEWPLYQEQEQEPEQEHEPGREQVEEQLEQIEEQQQLEQHQQLEQHQQLMQQSVAPPTAARGRISRLKLKEEQYIVIAPDKPETELPQYMHCDANCDQSLATNNNNNNQLQATPSNDFATADGAQRQATLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGEEDTASESEAEQLYGDFYCGECGISFHRQDLLRRHCKQQHSKHLTATTAVGNNNSVATATATDAVCVAAAGATDADADADADDAKDAPHCCHTCGKSFPNVLKLLAHAEIHKRFPPFKCVLCGVSFYEEQAIKRHLSTRHPHELKQNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKGRLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKMFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVALGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKAGGVDGEVGEEEDYVSDLDYCDLDVENVDELLQEATAEPPPPPAKKAKRKRKAPIKSGDEQRLWDEKFLQQTSNGNSDEAYKSFFQMDSLVVVNDQTLQPVDAAKLQQAEIKEQKLKAGSRSSKRRAAKAGGGAGAAGGGAAGAGGGGAAAAPRPRMIHTAKSQQTTSKKSRTRSYITRTSTNEQQQQQGRGGGATGGSLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHHHHHHHHQQHQQHHHQQQQRAQLLFDDSHLLIDAGLLREKTYEKYNPSIVQDLEEILRSPPKHERDDRRLRFTSESSTTPQFLPGEEEEQHLIKIEPTSPDLREMVESQQPATLPASSSVGSTAARTSRHLRQLTAKGSGSGSILTATSSSSATTSTRSASKRNASKQLSKKSTSNSNKGNSSSSYLNYGVDSYHVGVVASATSSSDVSSGFFSISEVVSAADAADAAAKAAAAASKTERKTRCFECEMCSSNFPDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00542584;
90% Identity: iTF_00499020;
80% Identity: -