Dmul009808.1
Basic Information
- Insect
- Drosophila mulleri
- Gene Symbol
- -
- Assembly
- GCA_035047565.1
- Location
- JAWNPK010000060.1:8725249-8725676[-]
Transcription Factor Domain
- TF Family
- zf-LITAF-like
- Domain
- zf-LITAF-like domain
- PFAM
- PF10601
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 3e-12 3.2e-09 36.9 14.8 2 68 42 111 41 113 0.81
Sequence Information
- Coding Sequence
- ATGGCCACAACAActgaggagcagcagcagcaacagcagcagctaaagcagGCAAAAAAGGAGCTCGAGATCTACGAGAATTTCGCCACACCTTTGCCGGGCACCTTTCTCAATTTGCCGCAGGAGTCGGTGCTGCTGAAGTGCCCGTCCTGCGGGATCAAGGATAAGACAGTGGTGGAAAACGATCTGAAATGGTGGGCCAGTGAGCTGAATCGCATTGTTGGCTGCCTCTTTGTcaccttctgctgctgctgctgcctggacTACATAGTGCCGTGCAAGCAAACCGATCGCAGTCATTATTGCGGCAACTGCGGCTGTTACTTTGGACGCGCCATGAAGCGACGAGCCCCACTCAAAATCAAATAg
- Protein Sequence
- MATTTEEQQQQQQQLKQAKKELEIYENFATPLPGTFLNLPQESVLLKCPSCGIKDKTVVENDLKWWASELNRIVGCLFVTFCCCCCLDYIVPCKQTDRSHYCGNCGCYFGRAMKRRAPLKIK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00804860;
- 90% Identity
- iTF_00540769; iTF_00479854; iTF_00473460; iTF_00554749; iTF_00477026; iTF_00547042; iTF_00510212; iTF_00502923; iTF_00599983; iTF_00520304; iTF_00494065; iTF_00532786; iTF_00545651; iTF_00559893; iTF_00573721; iTF_00516670; iTF_00544895; iTF_00587080; iTF_00572993; iTF_00568648; iTF_00513136; iTF_00582638;
- 80% Identity
- iTF_00479854; iTF_00473460;