Dmul012288.1
Basic Information
- Insect
- Drosophila mulleri
- Gene Symbol
- -
- Assembly
- GCA_035047565.1
- Location
- JAWNPK010000069.1:6019656-6023623[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 7.2 5.6e+02 1.5 2.0 1 23 177 203 177 203 0.86 2 13 0.00085 0.066 13.8 1.2 1 23 209 232 209 232 0.97 3 13 8.7e-05 0.0067 16.9 2.0 1 23 237 260 237 260 0.96 4 13 0.0003 0.023 15.2 4.6 1 23 265 287 265 287 0.98 5 13 4.9 3.8e+02 2.0 4.5 2 23 294 317 293 317 0.89 6 13 0.00045 0.035 14.7 1.0 3 23 327 348 326 348 0.95 7 13 0.13 9.8 7.0 0.1 1 23 354 377 354 377 0.95 8 13 0.048 3.7 8.3 0.2 5 23 393 412 388 412 0.90 9 13 2.8e-05 0.0022 18.5 0.4 1 23 442 464 442 464 0.98 10 13 1.4e-05 0.0011 19.4 5.3 1 23 470 492 470 492 0.96 11 13 8.3e-06 0.00064 20.1 0.1 2 23 499 520 499 520 0.97 12 13 0.0011 0.087 13.4 0.9 1 23 527 549 527 549 0.99 13 13 0.00033 0.026 15.1 3.9 1 23 555 578 555 578 0.98
Sequence Information
- Coding Sequence
- ATGGAAACGTGTCGCACCTGTGCAAGGTGCGATTTCGAAAATGGCAACAACTATTGGCTGGATATGTTTCATCCAACGCGCTGGCAGAGTGAAATGGCGCAAATTCGCGCAGAGTTTGTCAACTGGAAGTTACAGaTCTCTCCAAACGATGGACTCCCACAAAAAATTTGTAGCGATTGCTTTACAAAGTTCTGTTCCGTTTACACGTTTCGCATGGCTTGCCAAGACGCACAATTAAAGCTTTcgaatatttttgataaaatcGATGCTAACTTGCTGTATGACAGAAATGAAGAAAGCATTGAAGTTGATCCTGATGAATCAGAAGCTACAACGAAAACATGTACAGTAGCAgaaacagtaacaacaacgacaacaacaacaaagaacacTGCCATTAATGCGGCCAAATCGCCCGCGCCCATTGAAATCTTTGTGGAAACCATTAACATTAACGAAAGCGAATCCTTGCAGCTAGAAGATAAGGAAGTCGACTTAGGCTCAGATTGTAATACTTTGAATATAAGCTATGCTTGTAAGTTCTGTTATAAGCCGCAAGAAAGCTTTGAGCTACAACACTTGTTACTAGAGCACATTAGCGTCTGCCACGATCCAGATCAACCCTACAACTGCCCGGAGTGCACTGAATGTTTTCAAGACACAGCATCGCGTACCGTTCACATGAAGAGCGTTCATGTGGTCAAGCACTATGCCTGTGAAGTTTGTGGCAAAAAGTATGGAGACCGCCACAATCTCGACCATCACATTGAGAAGTATCACTCGGATACGGACTTCGAGTGCAGCATGTGCGAGAAGCGTTTTTTTACGCGCAAAAGTCTGCACTACCACATGAACTGGCACAAGCCGGAGCGTCAACTCCGATGTCGTCATAACGGCTGTGACCGGCTGTTCATCAATCAACGACATCTCATATGTCACGAGGCCACCCACACAAAGGGCTCCCGTAAGAGCGAGTACTGTGGCTTTTGTGGTAAAGCATTCATACATGTAAAAACCCTTCGTTGGCATATCTATCGACAGCATGGCGGAGAGAAGCCTTTCAAATGCGCCATCTGCACTGACGTGTTTGCCTCCTATGTGGAGAAACGCATTCATATGCTTGAGCTGCACACGGAAAATCTGACGCATCAGGAGCGTAGCGAGTGCATGTTTCAGTCCTGTCGCCAGGAGTTCGACACGGAGCAGGAGCTCATCCAACACATGAACATGGAGCATGCACCGCGTGAAACTTCCTCAGCTCCGATCATCGCGAACAATAAGCGAGTGATCCAATGCAAAAGGGAACGACAATATACGGGTCTCTTCCAGTGCGGCAGCTGCACGCAACGTTTCAACATGAAGTCCGCCTTGGAGCGTCACATGGCTGTCCACTCAACGGATCGGCTGCACGCCTGCTCGCACTGCTCCAAGCGTTATAAGCGTGCTCAGGATCTGAAGTGGCATATGAAAACccatgcaaatgaaaagccTAATGTATGCGATGTATGCGGCAAGGCCTTTGCCTTGAAATATGTCCTAACTCAGCATATGCGCAGTCATGAGGttcttGAAAAGAATTTCAAGTGTGAGACCTGTGGACGGGCGTATCTGTTTGAAAAGTCATTACGGTTGCATCAACGCGTACACACAGGCAATACCTACTATAAATGCGATCTGTGCCAAGAGCGATTTGTCACTCAcatcaaatttaaaaCTCACATGAAGAAGGCACATGATGGTGACCAGTCGCATTCTAAGGATACGCTGGATGATTTGATCAATATTGTGATTAACTAA
- Protein Sequence
- METCRTCARCDFENGNNYWLDMFHPTRWQSEMAQIRAEFVNWKLQISPNDGLPQKICSDCFTKFCSVYTFRMACQDAQLKLSNIFDKIDANLLYDRNEESIEVDPDESEATTKTCTVAETVTTTTTTTKNTAINAAKSPAPIEIFVETININESESLQLEDKEVDLGSDCNTLNISYACKFCYKPQESFELQHLLLEHISVCHDPDQPYNCPECTECFQDTASRTVHMKSVHVVKHYACEVCGKKYGDRHNLDHHIEKYHSDTDFECSMCEKRFFTRKSLHYHMNWHKPERQLRCRHNGCDRLFINQRHLICHEATHTKGSRKSEYCGFCGKAFIHVKTLRWHIYRQHGGEKPFKCAICTDVFASYVEKRIHMLELHTENLTHQERSECMFQSCRQEFDTEQELIQHMNMEHAPRETSSAPIIANNKRVIQCKRERQYTGLFQCGSCTQRFNMKSALERHMAVHSTDRLHACSHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKAFALKYVLTQHMRSHEVLEKNFKCETCGRAYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKKAHDGDQSHSKDTLDDLINIVIN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00502704;
- 90% Identity
- iTF_00573493;
- 80% Identity
- -