Dmul008660.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila mulleri
Gene Symbol
ftz-f1
Assembly
GCA_035047565.1
Location
JAWNPK010000052.1:1017459-1026917[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 2 1.9e+04 -13.0 25.5 45 156 30 148 7 167 0.33
2 4 0.85 8.3e+03 -4.1 14.6 57 138 90 169 76 195 0.42
3 4 1e-19 1e-15 58.2 0.1 1 80 328 406 328 453 0.79
4 4 8.4e-73 8.1e-69 233.1 0.4 154 409 521 769 491 770 0.92

Sequence Information

Coding Sequence
atgttattAGAAATGGATCCTCAACAGGCGACAGTACAGTTCATATCATCGCTGAATCTGTCCCCGTTTAGCATGCAGCTTGATCAACAGCAGCCGGCCAGTCCCGTGCagagcaacaccaacaacaataacagcagcagcagcggaaacaacaacaacaacagcaacaacaacaataataataatactagtAACAATGATAACGATACAAATCCTTTAAGCAATTCCGATAACGATTACAGCGCCTATACGCTGCAGTTGGGCaatcatcaacagcaacagccgcagcagcagcaacaacagcaacagcacctcAATacgcatcatcagcaacaccaacaacaacattatcaacagcaacaacaacagaatattgccaacaacaatgcgaataGTGCTGCGAACCAATTCAATGCCTCCTCttattcgtatatatacaatttcgatTCACAGTATATATTTCCGACAGGCTATCAGGAAACCAATTCGTCCCATTCGCAGCAAAGTGGCAACGGCACCGGCGTAGCATCTGGCAACTCTGGCCAGCTGCTGAacggtggcagcagcagctctgccGGTAACGGCTATATGTTGCTGCCACCTGGTGGTACCTCAGCTGTACACATGACCGGCAATGTCGGTGGCACCGGAGCAGCAGGTGGAGCTGGCAGTGTCGTCTCTACAGGTGGCGTAGGCGGTGGCCATAATGGAGGAACTAGCGCCACCTCTGGCGGAGGCGAAGCCATCGACTTCAAGCACTTGTTCGAGGAACTGTGCCCTGTCTGCGGCGATAAAGTCAGCGGCTATCACTACGGTCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGGACcgtacaaaacaaaaaggtgTACACATGCGTCGCGGAACGCTCCTGCCACATCGACAAAACGCAGCGCAAGCGCTGTCCATACTGCCGATTCCAAAAGTGCCTCGAAGTGGGCATGAAACTTGAAGCGGTTCGAGCAGATCGCATGCGTGGAGGCCGTAACAAATTTGGACCCATGTACAAAAGGGATCGGGCGCGCAAGCTTCAGGTTATGCGACAACGGCAACTGGCCCTTCAGGCGCTGAGGAGCTCTATTGGCTCAGATATAAAGCCAACGCCCCTCTCCCCTGGCTATCAGCAAGCATAtccaaatatgaatattaagcAAGAAATTCAAATACCTCAGGTATCATCACTCACGCAGTCGCCAGACTCATCACCTAgtcccattgccattgctttGGGCCAGGTGAATGCTGGCGCTGGCGGTGTGATAGGCACGCCTCTGAATGTTGGCAATTTGAGTGGTGGCAGTTCGCTAGGCAATggcaacactaacaacaataGCGCAGGAAGTGCTGGCGGGGGCAGTGGGGGTGGCAACAATGCTGGCACCGGAAGCggtgccaacaacagcaacaacataccTGATGGCCTGCAACGTAACGGAAACAGCGGCaatagcaacagtaacagcagctgccatgaTGCTGGGAATGGATCTCTGCAGAACACAACTGAATCGAAATTGTGctttGATTCTGGCACACATCCATCGAGCACGGGGGACGCGGTCATTGAACCCCTGAGGGTCTCGCCAATGATACGAGAGTTTGTGCAATCGATCGATGATCGGGAATGGCAGACTCAGCTTTTTGCGCTACTGCAAAAACAGACATATAACCAAGTTGAAGTTGATCTCTTTGAGTTGATGTGCAAAGTGTTGGATCAAAACCTCTTCTCACAAGTGGATTGGGCAAGGAACACGGTCTTCTTTAAGGACTTAAAGGTGGACGATCAGATGAAGCTGCTTCAGCATTCTTGGTCGGACATGCTTGTACTGGATCATCTGCATCATCGCATACATAACGGTTTGCCGGATGAAACGCAACTTAATAACGGACAAGTGTTTAACTTAATGAGCCTTGGTCTGCTTGGAGTGCCACAGTTGGGCGACTATTTTAATGAGTTGCAAAACAAGCTGCAGGACCTGAAGTTTGATATGGGCgactatgtgtgtatgaaatTCCTAATACTTTTAAATCCAGATGTACGTGGAATTGTGAACAAAAAGACCGTTGTAGAGGGACACGAGAATGTTCAAGCAGCTTTGCTAGATTATACACTTACGTGTTACCCCTCAGTAAATGACAAATTTAGGAGGCTTTTGAATATCCTACCGGAAATTCATGCCATGGCCGCGCGCGGCGAAGAACATCTATACTCAAAACATTGTGCGGGCAGCGCACCAACGCAGACGCTGCTCATGGAGATGCTGCATGCTAAACGAAAGGGGTGA
Protein Sequence
MLLEMDPQQATVQFISSLNLSPFSMQLDQQQPASPVQSNTNNNNSSSSGNNNNNSNNNNNNNTSNNDNDTNPLSNSDNDYSAYTLQLGNHQQQQPQQQQQQQQHLNTHHQQHQQQHYQQQQQQNIANNNANSAANQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSGNGTGVASGNSGQLLNGGSSSSAGNGYMLLPPGGTSAVHMTGNVGGTGAAGGAGSVVSTGGVGGGHNGGTSATSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSIGSDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNAGAGGVIGTPLNVGNLSGGSSLGNGNTNNNSAGSAGGGSGGGNNAGTGSGANNSNNIPDGLQRNGNSGNSNSNSSCHDAGNGSLQNTTESKLCFDSGTHPSSTGDAVIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPDVRGIVNKKTVVEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00479510;
90% Identity
iTF_00532403;
80% Identity
iTF_00551640;