Basic Information

Insect: Drosophila monieri
Gene Symbol: -
Assembly: GCA_035047585.1
Location: JAWNPJ010000082.1:8894213-8897638[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0011 0.087 13.4 3.2 3 23 313 334 311 334 0.96

2 18 0.44 35 5.2 0.2 1 23 341 366 341 366 0.91

3 18 0.032 2.5 8.8 2.2 2 23 377 398 377 398 0.93

4 18 0.049 3.9 8.2 0.3 3 23 439 460 438 460 0.95

5 18 0.0012 0.097 13.3 0.4 3 23 468 488 466 488 0.95

6 18 0.062 5 7.9 0.1 1 23 496 519 496 519 0.96

7 18 0.00092 0.073 13.7 0.3 2 23 524 545 523 545 0.96

8 18 1.7 1.4e+02 3.4 0.4 2 21 554 573 554 574 0.91

9 18 0.43 34 5.3 3.9 1 22 593 614 593 617 0.89

10 18 0.035 2.8 8.7 2.5 3 21 624 642 622 643 0.93

11 18 0.0036 0.29 11.8 0.2 1 23 662 687 662 687 0.97

12 18 0.22 17 6.2 1.7 2 23 705 727 704 727 0.94

13 18 0.0066 0.52 11.0 0.2 2 23 733 755 732 755 0.92

14 18 0.43 34 5.3 0.1 2 23 759 781 758 781 0.95

15 18 4.4e-05 0.0035 17.8 2.0 1 23 787 809 787 809 0.97

16 18 0.012 0.92 10.2 1.0 1 23 813 836 813 836 0.93

17 18 9.3e-06 0.00074 19.9 1.2 1 23 842 865 842 865 0.97

18 18 2.7e-05 0.0022 18.5 0.2 4 23 872 897 869 897 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0011	0.087	13.4	3.2	3	23	313	334	311	334	0.96
2	18	0.44	35	5.2	0.2	1	23	341	366	341	366	0.91
3	18	0.032	2.5	8.8	2.2	2	23	377	398	377	398	0.93
4	18	0.049	3.9	8.2	0.3	3	23	439	460	438	460	0.95
5	18	0.0012	0.097	13.3	0.4	3	23	468	488	466	488	0.95
6	18	0.062	5	7.9	0.1	1	23	496	519	496	519	0.96
7	18	0.00092	0.073	13.7	0.3	2	23	524	545	523	545	0.96
8	18	1.7	1.4e+02	3.4	0.4	2	21	554	573	554	574	0.91
9	18	0.43	34	5.3	3.9	1	22	593	614	593	617	0.89
10	18	0.035	2.8	8.7	2.5	3	21	624	642	622	643	0.93
11	18	0.0036	0.29	11.8	0.2	1	23	662	687	662	687	0.97
12	18	0.22	17	6.2	1.7	2	23	705	727	704	727	0.94
13	18	0.0066	0.52	11.0	0.2	2	23	733	755	732	755	0.92
14	18	0.43	34	5.3	0.1	2	23	759	781	758	781	0.95
15	18	4.4e-05	0.0035	17.8	2.0	1	23	787	809	787	809	0.97
16	18	0.012	0.92	10.2	1.0	1	23	813	836	813	836	0.93
17	18	9.3e-06	0.00074	19.9	1.2	1	23	842	865	842	865	0.97
18	18	2.7e-05	0.0022	18.5	0.2	4	23	872	897	869	897	0.83

Sequence Information

Coding Sequence: ATGTcggaaaaccaaaataaacaaagctgCCTGCATTGTAGAGTATTCAATCCGAAATTCAGGTACCAGGAGATATTTGATGAGTTTGGAACCGAGCTGGGCCTGCAATCCTTGCTAGAAAAGCACTTTGACTTGAATGTGGCACCAAACTCCAATGAGCAGCAGCTGCTGTGCGAAGTTTGCGTCAACAGTTTAATTCGCCTCTTTGACATCGATGAACTGCAGCGGGAACAGGATGCGGCGAAGGATAAGGCCAAAGAGACTGCTCCTGACCACCAACTATCGGTGGCTATCCCAGAATCCAGTGCAGCTGCTACAAAACAGGTAGCTTCTCCAAAGACTAAGACCGTTAAAACAGTTCCAGTTGTTCCGAAAAGAGAAAACAGTCTTCGCATCAACAAGGAACCACCAACACCACTCCATATTGCTCCTACTACTTCCCAGGATTTTGACAAAGTCAAGGAGCAGGCTATATCAGCTCCCCCCGCCAAGTTACAATCAAAAGGGGCTCCAAAGGAATCGGATCAGGAGCAGATCAGTCGCCTCATTCGCAACATCCTGAACGACGATGAGGTGATCGTTGAAGAGGTTTCCGCTCCAGTTCCAGAGGAAGTTGAAAAGCACGAGGAAATAGTCCTGCTGGACAGCGAGTCTATTCCTGACACGGATCTAGATCAGGAGGAATTCATTTATGACCATGAAGatatcCTAGACCCTGTCTTGCCTGATTTAAAGTTGAAGCCAGAGTCCCGAGCGAAGGTGGATGCGGAGGATAGTCAGAGTGAAGGAGAGGTCGATGGAAGCGAATCTAGCAATATTATTATCTTCAACTTTGTTGAGATCAAAGATCATGACGATATTGGTAACATCTTCGAATACTTGTCCACGGTGGTCAAAACCAGCTTTGAGAAACTATCTTTCGAATGGTGCACAGATTGCAAACACTGCTCCAAAAAGTTTCGAAACTTTAACTCTCTCCTAAGTCATGTTCTAACAGCTCATAAGTCTAGAGGTAATGTCTTCAGGTGTCCTTTAAAGGACTGCAGCAAGGAGCTGAAAGGAAGCAAATTTCTGGCCATGCATTTGGTGCTCATGCATGCACAAGTGGCAGACATTCCAATCTATGGCAGCTGTCCGGAGTGCAAAATGACATTTTCAAACATTCTCCAATACAACAAACACTCCTGCGCCCATGTCATCAAAAAGAAGCGAGGAGTTCGGCTTTTCTGCGAAATGTGTGCCCAAGACTTTCCTTCCTGGAAGCGTTTCAACTTTCACAATCAATTCCATCTGGAGAAGCACAGGCCTCGTAATTGCTTCATCTGCGATTATGCCAGCAATAATATTGACGAACTTTTCCAGCACTTGAATTACTTCCATGAGCCAGAGGGAACTCTGTTCTGTGATATTTGTGATCGTACTTTCCGTGATGCGGAGGTGTTCACAGAGCACAACAAATCCCATGCCAATGTTAGTGGCACCACCTTTACCTGCGGTGAGTGCATGGCCATGTTTGAGTCTCGCGGTCGATTGAATGGGCACATGAGAGCTATGCATGGCAGCGCCATAAGCTGCAAATGGTGCTCCCGCGAGTTCGCCAGCGAGGCTACCTACAACGTCCACATGAAGCAGCACGTGATCATCGAAAGGGGTGTCAATGTGTGCAGCAAATGCGGCCAGCTAAGCGACAACCACAATAATATGCAGGATCATGTCAATAATGAGGAGTCCCCCTGTTTTCAAGCAAAGGTTTTTACGGAACTCCTTCGCAATGCTTATGTTTGCGAGCACTGCTCGCTGTACtttaaagaaaagaaggacCTGCAGTGCCACCGGCAATCCGGAGTGCATAAGAACGGGTTGTATTGGTGCCATCCGTGTGGCAAGGAGTTTTCTCATATGAAACTATACCGCCACCATATTCGTAACTTTCAGCAAATAAGGGGAGATGCCACGCACTGCAAGCTGGAAATCGGTGTTTTCTACGTGTGCGATCAGGAGGGCTGTTCTGAGGCTTATGCCAATTGGAATTCCTTGTACACGCACAAGCGGCGAACACATGAGACTCCCAGCAAGCAGGctaaaaaaacttcaaaatctGAACAGGAATGGGTGTGCCAGTTCTGTCTGAAGCAGTGCCGCTCCAAGATGTCCTTGTCAGTTCATGTAGCAAGAAGCCACAACAATGACAATGTTGTCTGCCCTTTGTGTAGCGCTTCTTATAAGAACCAGGAAGCCTTGGACAAGCACCATGCCTACTGGCACGAGCCCATCGAGTGTCCACAGTGCAtcaaaattgtgaaaaacCGACGGAACTATGATACTCATGTAAACGTAGTGCATTCCAATACGAAGCGCTATGCCTGCAGTGTTTGTCAAAAGGGTTTTTATCACAAAAGCGAAATGGAGTCACATCAGAGACTCCATGGCCAGTCCTTCAGTTGTGACCAGTGCAGCTTCACCACCAGGAACAAGAAGTCGCTGTCCGTCCACGTTCTCGGTCAGCACTACAAACGATTCGCGTTCGAGTGCAAGATGTGCAGCAAGCGATTTGGACGCCAACAGGGCCTGAACACCCACATGCAGCGAGCTCACGGATCAAAGTTCATGTGCCGGGACTATTTTGAGGGCGGCTGTGGGCGCAGCTTCATCAACAGTTCCCAGTTGAATGTGCACGTACGCAAGGTGCACAATGGCACTATTTTTCTGACcgaggaagaggaggaagaGTACCTCAGCGATGGGCCATCGACGTCTAAAAAACGATGCTTTAGGATAGACGATGATACGAACATCGAGTTTATAGAGGATCCAGAAACCACACAAGATGGAGTACAAATTGTGGATGAAATCGATGAGGATGATTACGTGGAAGAATGTTTAGTTGCCAAGAATTGA
Protein Sequence: MSENQNKQSCLHCRVFNPKFRYQEIFDEFGTELGLQSLLEKHFDLNVAPNSNEQQLLCEVCVNSLIRLFDIDELQREQDAAKDKAKETAPDHQLSVAIPESSAAATKQVASPKTKTVKTVPVVPKRENSLRINKEPPTPLHIAPTTSQDFDKVKEQAISAPPAKLQSKGAPKESDQEQISRLIRNILNDDEVIVEEVSAPVPEEVEKHEEIVLLDSESIPDTDLDQEEFIYDHEDILDPVLPDLKLKPESRAKVDAEDSQSEGEVDGSESSNIIIFNFVEIKDHDDIGNIFEYLSTVVKTSFEKLSFEWCTDCKHCSKKFRNFNSLLSHVLTAHKSRGNVFRCPLKDCSKELKGSKFLAMHLVLMHAQVADIPIYGSCPECKMTFSNILQYNKHSCAHVIKKKRGVRLFCEMCAQDFPSWKRFNFHNQFHLEKHRPRNCFICDYASNNIDELFQHLNYFHEPEGTLFCDICDRTFRDAEVFTEHNKSHANVSGTTFTCGECMAMFESRGRLNGHMRAMHGSAISCKWCSREFASEATYNVHMKQHVIIERGVNVCSKCGQLSDNHNNMQDHVNNEESPCFQAKVFTELLRNAYVCEHCSLYFKEKKDLQCHRQSGVHKNGLYWCHPCGKEFSHMKLYRHHIRNFQQIRGDATHCKLEIGVFYVCDQEGCSEAYANWNSLYTHKRRTHETPSKQAKKTSKSEQEWVCQFCLKQCRSKMSLSVHVARSHNNDNVVCPLCSASYKNQEALDKHHAYWHEPIECPQCIKIVKNRRNYDTHVNVVHSNTKRYACSVCQKGFYHKSEMESHQRLHGQSFSCDQCSFTTRNKKSLSVHVLGQHYKRFAFECKMCSKRFGRQQGLNTHMQRAHGSKFMCRDYFEGGCGRSFINSSQLNVHVRKVHNGTIFLTEEEEEEYLSDGPSTSKKRCFRIDDDTNIEFIEDPETTQDGVQIVDEIDEDDYVEECLVAKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00481678;
90% Identity: iTF_00481678; iTF_00476090; iTF_00477491;
80% Identity: -