Basic Information

Insect: Drosophila ananassae
Gene Symbol: -
Assembly: GCA_017639315.1
Location: CM029942.1:4515993-4519440[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.0012 0.088 13.2 3.5 3 23 319 340 317 340 0.97

2 18 7.6 5.8e+02 1.2 0.2 1 22 347 370 347 372 0.85

3 18 0.029 2.2 8.8 2.2 2 23 383 404 383 404 0.93

4 18 0.045 3.4 8.2 0.3 3 23 445 466 444 466 0.95

5 18 0.00067 0.051 14.0 0.4 3 23 474 494 472 494 0.95

6 18 0.11 8.3 7.0 0.1 1 23 502 525 502 525 0.96

7 18 0.00055 0.042 14.2 0.2 2 23 530 551 529 551 0.97

8 18 1.5 1.1e+02 3.4 0.5 2 21 560 579 560 580 0.91

9 18 0.28 21 5.7 4.1 1 23 599 623 599 623 0.92

10 18 0.046 3.5 8.2 1.8 3 21 630 648 630 649 0.90

11 18 0.0048 0.37 11.3 0.3 1 23 668 693 668 693 0.96

12 18 0.2 15 6.2 1.7 2 23 711 733 710 733 0.94

13 18 0.00032 0.024 15.0 0.2 2 23 739 761 738 761 0.92

14 18 0.11 8.1 7.0 0.1 2 23 765 787 764 787 0.95

15 18 4e-05 0.0031 17.8 2.0 1 23 793 815 793 815 0.97

16 18 0.012 0.92 10.0 1.0 1 23 819 842 819 842 0.93

17 18 8.6e-06 0.00065 19.9 1.2 1 23 848 871 848 871 0.97

18 18 2.5e-05 0.0019 18.5 0.2 4 23 878 903 875 903 0.83

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.0012	0.088	13.2	3.5	3	23	319	340	317	340	0.97
2	18	7.6	5.8e+02	1.2	0.2	1	22	347	370	347	372	0.85
3	18	0.029	2.2	8.8	2.2	2	23	383	404	383	404	0.93
4	18	0.045	3.4	8.2	0.3	3	23	445	466	444	466	0.95
5	18	0.00067	0.051	14.0	0.4	3	23	474	494	472	494	0.95
6	18	0.11	8.3	7.0	0.1	1	23	502	525	502	525	0.96
7	18	0.00055	0.042	14.2	0.2	2	23	530	551	529	551	0.97
8	18	1.5	1.1e+02	3.4	0.5	2	21	560	579	560	580	0.91
9	18	0.28	21	5.7	4.1	1	23	599	623	599	623	0.92
10	18	0.046	3.5	8.2	1.8	3	21	630	648	630	649	0.90
11	18	0.0048	0.37	11.3	0.3	1	23	668	693	668	693	0.96
12	18	0.2	15	6.2	1.7	2	23	711	733	710	733	0.94
13	18	0.00032	0.024	15.0	0.2	2	23	739	761	738	761	0.92
14	18	0.11	8.1	7.0	0.1	2	23	765	787	764	787	0.95
15	18	4e-05	0.0031	17.8	2.0	1	23	793	815	793	815	0.97
16	18	0.012	0.92	10.0	1.0	1	23	819	842	819	842	0.93
17	18	8.6e-06	0.00065	19.9	1.2	1	23	848	871	848	871	0.97
18	18	2.5e-05	0.0019	18.5	0.2	4	23	878	903	875	903	0.83

Sequence Information

Coding Sequence: ATGTCGGAAAACCAAAATAAACAAAGCTGCCTGCATTGTAGAGTATTCAATCCGAAATTCAAGTACCAGGAGATATTTGACGAGTTTGGAACCGAGCTGGGCCTGCAATCCTTGCTAGCCAAGCACTTTGACTTCAATGTGACACCAAACTCCAACGAGCAGCAGCTGCTGTGCGAAGTTTGCGTCAACAGTTTAATCCGCCTCTTTGACATCGATGAACTGCAGCGGGAACAGGATGCGGCGAAGGATAAAACCAAGGAGCCTGCTCCTGAACAGAAAGTATCGGTGGCTATCCCAGAATCCATGGCAGTGCCAACACCACCTGAGCATCATGCAGCACAACAGGTTGCTTCTCCAAAGGCTAAGACCGTTAAAACAGTACCAGCTGTTCCAAAAAGAGAGCACAGTCTTCGCATCAACAAGGATCCATCAAAACCACTCCAGATTGCTCCTACTACTTCCCAGGATTTTGATAACGCCAAGGAGCAGCCTATTTCAGCTCCTCCCGCCAAACAATCAAAAGGAGTTCCAAAGGAATCGGAACAGGAGCAGATCAGTCGCCTCATTTGCAACATCCTGAACGACGATGAGGTGATCGTTGAAGAGGTTTCAGCCCCAGTTCCAGAGGAAGTTGAAAAGCATGAGGAAATAGTCCTGCTGGACAGCGAATCTATCCCTGACACGGATATAGATCAGGAGGAATTCATTTACGACCATGAAGATATCCTTGACCCGGTGCTGCCTGATTTAAAGTTAAAGCCAGAGACTCGAGCGAAAGTGGAAGCAGAGGATAGTCAGAGTGAAGTAGAGGTCGATGGAAGCGAATCTAGCAATGTCATTATCTTCAACTTTGTTGAGATCAAAGATCATGATGATATTGGTAACATCCTCGAATACCTTTCCACGGTGGTAAAGACCAGCTTTGAGAAACTCTCATTCGACTGGTCCACTGATTGCAAACACTGCTCCAAAAAGTTTCAAACCTTTAACTCTCTCTTAAGTCATATGCTAACAGCTCATAAGACTAGAGGTAATGTCTTCAGGTGTCCTCTAAAGAACTGCAGCAAGGAGCTAAAAGGGGTCAAATTTCTGGCCATGCATTTGGTGCTCATGCATGCAAAAGTGGGAGACATTCCAATCTATGGCAGTTGTCCGGAGTGCAAAATGACGTTTTCAAACATTCTTCAATACAACAAACACTCCTGCGCCCATGTCATCAAAAAGAAGCGAGGTGTCCGGCTTTATTGCGAAATGTGTGCCTTGGACTTTCCTTCCTGGAAGCGTTTCAACTTTCACAATCAATTTCATCTGGAGAAGCACAGGCCCCGTAATTGTTTCATCTGCGATTATGCCAGCAATAATATTGACGAACTATTCCAGCACCTGAATTACTTCCATGAGCCAGAAGGAACTCTTTTCTGTGATATTTGTGATCGCACCTTCCGAGATCCCGAGGTTTTCACAGAGCACAACAAATCCCATACCAATGTTAATGGCACCACCTTCACCTGCGTTGAGTGCATGGCCATGTTCGAGTCTCGGGGTCGATTAAATGGGCACATGAGAGCTATGCATGGCAGTGCCATAAGCTGCGAGTTGTGCTCCCGGGAGTTCGCCAGCGAGGCCACCTACAACGTCCACATGAAGAAACACTTGATCATCGAAAGGGATGTCAACGTGTGCAGCAAATGCGGCCAGTTAAGCGATAGCCACAAGAACATGCAGGATCATGTGAATAACGAGGAATCCCCTTGTTTTCAAGCAAAGGTTCTTACGGAACTCCTTCGCGATGCCTATGTTTGCGAGCACTGCTCGCTGTACTTTAAAGAAAAAAATGACCTGCAGTGCCACCGAAAAACGGGAGTGCATAAGAACGGGTTGTATTGGTGCCAACCGTGTGGCAAGGAGTTTTCTCACATGAAACTATACCGTCACCATATTCGTAACTTTCAGCAAATAAGGGGGGATGCCACACACCGCAAGCTGGAGATCTGTGTTTTCTACATGTGTGATCAGGAGGGCTGTTCTGAGGCTTATGCCAATTGGAATTCCTTGTATACGCACAAGCGAAGAACACATGAGACTTCCAGCAAGCAGGCTAACAAAACTTCAAAGTCTGAACAGGAGTGGGTTTGCCAGTTCTGTTTGAAGCAGTGCCGTTCCAAGATGTCCTTGTCAGTTCATGTAGCCAGAAGCCACAATAATGACAATGTTGTCTGCCCTTTGTGTAATGCTTCTTATAAGAACCAGGAAGCCTTGAACAAGCACCATGCCTACTGGCACGAGCCCATCGAATGTCCCCAGTGCTTTAAAATTGTCAAAAACGTACGGAACTATGATACCCATGTCAACGTGGTGCATTCCAATACGAAGCGGTATGCCTGCAGTGTCTGCCAAAAGGGTTTCTATCACAAAAGCGAAATGGAGTCACATCAGAGACTCCATGGACAGTCATACAATTGTGACCAGTGCAGCTTCACCACCAGGAACAAGAAGTCTCTCTCTGTCCACGTTCTGGGTCAGCACTACAAACGCTTCGCTTTCGAATGCAAGATGTGCAGCAAGCGCTTTGGACGCCAACAGGGCCTGAACACCCACATGCAGCGAGCTCACGGATCAAAGTTCATGTGCCGGGACTACTTTGAGGGCGGCTGTGGGCGCAGCTTCATCAACAGTTCCCAGTTAAATGTGCACGTACGAAAGGTGCACAATGGCACTATCTTCCTCACCGAGGAAGAGGAGGATGAGTACATCAGCGATGGGCCATCGACGTCTAAAAAACGATGCTTTCGGATCGACGATGATACCAACATCGAGTTTATAGAGGATCCAGAAGCCACCCAAGATGGAATAGAACTTGAGCATGAAATCGATGAGGATGATTACGGAGAGGAGGGTTTAGTTGCCACGTCAGTTGCCAAGAATTGA
Protein Sequence: MSENQNKQSCLHCRVFNPKFKYQEIFDEFGTELGLQSLLAKHFDFNVTPNSNEQQLLCEVCVNSLIRLFDIDELQREQDAAKDKTKEPAPEQKVSVAIPESMAVPTPPEHHAAQQVASPKAKTVKTVPAVPKREHSLRINKDPSKPLQIAPTTSQDFDNAKEQPISAPPAKQSKGVPKESEQEQISRLICNILNDDEVIVEEVSAPVPEEVEKHEEIVLLDSESIPDTDIDQEEFIYDHEDILDPVLPDLKLKPETRAKVEAEDSQSEVEVDGSESSNVIIFNFVEIKDHDDIGNILEYLSTVVKTSFEKLSFDWSTDCKHCSKKFQTFNSLLSHMLTAHKTRGNVFRCPLKNCSKELKGVKFLAMHLVLMHAKVGDIPIYGSCPECKMTFSNILQYNKHSCAHVIKKKRGVRLYCEMCALDFPSWKRFNFHNQFHLEKHRPRNCFICDYASNNIDELFQHLNYFHEPEGTLFCDICDRTFRDPEVFTEHNKSHTNVNGTTFTCVECMAMFESRGRLNGHMRAMHGSAISCELCSREFASEATYNVHMKKHLIIERDVNVCSKCGQLSDSHKNMQDHVNNEESPCFQAKVLTELLRDAYVCEHCSLYFKEKNDLQCHRKTGVHKNGLYWCQPCGKEFSHMKLYRHHIRNFQQIRGDATHRKLEICVFYMCDQEGCSEAYANWNSLYTHKRRTHETSSKQANKTSKSEQEWVCQFCLKQCRSKMSLSVHVARSHNNDNVVCPLCNASYKNQEALNKHHAYWHEPIECPQCFKIVKNVRNYDTHVNVVHSNTKRYACSVCQKGFYHKSEMESHQRLHGQSYNCDQCSFTTRNKKSLSVHVLGQHYKRFAFECKMCSKRFGRQQGLNTHMQRAHGSKFMCRDYFEGGCGRSFINSSQLNVHVRKVHNGTIFLTEEEEDEYISDGPSTSKKRCFRIDDDTNIEFIEDPEATQDGIELEHEIDEDDYGEEGLVATSVAKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00481678;
90% Identity: iTF_00550405;
80% Identity: -