Basic Information

Insect: Drosophila monieri
Gene Symbol: ken1
Assembly: GCA_035047585.1
Location: JAWNPJ010000027.1:12803868-12806065[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00012 0.0094 16.5 3.3 2 23 183 204 182 204 0.97

2 12 0.00083 0.066 13.8 0.1 1 23 210 235 210 235 0.93

3 12 0.11 8.7 7.1 0.1 3 23 244 267 242 267 0.92

4 12 0.0012 0.095 13.3 1.0 2 23 280 301 279 301 0.96

5 12 9.1e-06 0.00072 20.0 0.6 1 23 308 330 308 330 0.98

6 12 0.0054 0.43 11.2 0.1 1 23 336 358 336 358 0.98

7 12 0.015 1.2 9.9 4.0 1 23 364 387 364 387 0.97

8 12 0.0098 0.77 10.4 4.0 1 23 393 415 393 415 0.96

9 12 0.00056 0.044 14.3 3.7 2 23 422 443 421 443 0.96

10 12 0.00027 0.022 15.3 1.1 3 23 532 553 530 553 0.95

11 12 0.01 0.83 10.3 0.7 1 19 559 577 559 581 0.95

12 12 1.4e-06 0.00011 22.5 2.8 1 23 587 609 587 609 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00012	0.0094	16.5	3.3	2	23	183	204	182	204	0.97
2	12	0.00083	0.066	13.8	0.1	1	23	210	235	210	235	0.93
3	12	0.11	8.7	7.1	0.1	3	23	244	267	242	267	0.92
4	12	0.0012	0.095	13.3	1.0	2	23	280	301	279	301	0.96
5	12	9.1e-06	0.00072	20.0	0.6	1	23	308	330	308	330	0.98
6	12	0.0054	0.43	11.2	0.1	1	23	336	358	336	358	0.98
7	12	0.015	1.2	9.9	4.0	1	23	364	387	364	387	0.97
8	12	0.0098	0.77	10.4	4.0	1	23	393	415	393	415	0.96
9	12	0.00056	0.044	14.3	3.7	2	23	422	443	421	443	0.96
10	12	0.00027	0.022	15.3	1.1	3	23	532	553	530	553	0.95
11	12	0.01	0.83	10.3	0.7	1	19	559	577	559	581	0.95
12	12	1.4e-06	0.00011	22.5	2.8	1	23	587	609	587	609	0.98

Sequence Information

Coding Sequence: ATGGACACCAGGGAGTACCGGGAGACCGGCCGCCGACTATGTCGCATTTGTCTTCTCGACTTGGAGCAGGCTTTTGGGCACGATTTGTTCGGGGAACCGGAGCTGGTGAAGAAATTCACAGTTTGCACTTCACTGGAGGCCGAAAAGCTGGATGGATATCCCAGTATCCTTTGCGAAAGATGCCATGGGAAGCTGAACGAGCTCCACGATTTCCGGGAATTGTGCTTGGTGTCCAGGCAGCGCTTTAAAGAAATGTTCGCTGGTAATTTGGTGACTTCAATGGAAGTATTTGAGCCTGTAAGGGAGGATTCTGAGGCGGAGGAGCAAGGCAGCTTCGATCCCCTCTTAAATCATAAACTGGAAGTTATTGACAATGAAGAGGAGGTGTTCAAGATGCTGGAAACGGTGGATAAAGACCCGGAGGAGCATCGAATCCCGGACGAATCATCCAACAATGAAGAGGATGAAGGGGAAGATGAGGTCGAAAAGCCTCTGCCCAAGCGACAGCATAATCCCACTAGGGAGCGCCTTCGCCTCCATCTTATTACATGTCCCATCTGCACCCAAAAGTTCAAGAAACAATCGAAATACGAGGAGCACATGAAGCACCACAACGATTTGTTGCCTTTTCAGTGCTCGGAGGAAACTTGCAAGAAGGGCTTCACCACAGCAGGTGCACTGCGTCTGCATGTTGACTATGCACATACGAAAAAGTCCAGCGAGATCCCCTGCACCGTGGAGGGTTGCAGGCTGCTCTTCCCTCGTCTCCGTCTATTGACGATTCACCTGAAAAAAGTGCACAACCAGACGAGAGTGAGCGCTCCTCGGGGGGATCAACCTTGTCGCGAATGTGGGATGGTCTTCCGGTGCCCGGTGGCGCTAAAAAAACACATGTACAAGCACACGGGCGAAGAGCTGCCGTATCCGTGCAACATATGCGGCAAGGGCTTCCACATAAACAGTGCCTTGAAAAATCACCTTCTGCGACATGCCGGGATTAAAAACTACGTGTGCCCCTACTGTGGAGTCGGGAAAACCACCAGGCAGGAATGGAGCAAGCATATCCTCACCCACACGCAGGAGAAGCAGTTCAAGTGCCACATCTGTGACCACGCCACCCACACCAAAAGGGCTTTGGACAGCCATGTGAAGATTGTCCACGAAAAGGTCAGGAACTTCGCCTGCCAATACTGCGGGAAGACCTTTGGGAAATCGCACGCTTGCAAGATTCATGAGATGACCCACACGGGGGAGAAGCGCTGCGAGTGCAAGgtttgCGGCAAGAAGTTCCTCTACACAGAGAGCCTGACCAAGCATCTAAAAACCCACGAGAAAAGCATGGAACGAGCTTTGGAAACCTATCGGCAGCGGCACGGCGAAGAAGACATTGCCGGAGCCCAGGTGGACGCGGATCAACTGCTAAAGGTTTGCGCTGAGTCTGTGGCGACCATACCCAAAGATCCACGGCGCGTGGAACGCGTTGATCTGGCCCAGTTGGCAGGGACGGTTGTTAATCCTATCTCGACGATCCAGCTGCCGCCGAGCGAGATGCCCACACGAACGAAATTTGTCCAGAAGGAAGGCATGCACCTATGCCCAGGCTGCAGTCAAGGATTCAACAATTTGGGAAACATGAAGCGCCACTACAAGAGCGTCCACGAGAAGGTGAAAGACTTTGAATGCCGCTTCTGCGCTCGTCGCTTCGCCAACTCGCAATCCTTGAAGCAGCACGAGTGGATTCACACCGGCGAGAAGCCGTATGAGTGCAAGCATTGCGGCACTCACTTTCGCCAGGAGGCGGCTCTCATTCGACACCAAAAGGTTCACGACAAGAGACCACCGAAGCCCCCCAAGCCACACAAGGAAATCACGGACAAGGCGCGCCAGAAGGCCATCCTGAAATGTGCCCACAAGCGGAAGGCAGAGGCCCTCAGAGAGGAGATCGCCGTAGTGGCCAAAGAGGAGCTGAAGGATCTGGAGAAGCAGCGGGCACTCGAAAAGCAGCATAAAACCTACGAACAGTatcaggcagcagcagcagccgagcAAACGCATTCCAAGTCCACTGAGGGATCTTAA
Protein Sequence: MDTREYRETGRRLCRICLLDLEQAFGHDLFGEPELVKKFTVCTSLEAEKLDGYPSILCERCHGKLNELHDFRELCLVSRQRFKEMFAGNLVTSMEVFEPVREDSEAEEQGSFDPLLNHKLEVIDNEEEVFKMLETVDKDPEEHRIPDESSNNEEDEGEDEVEKPLPKRQHNPTRERLRLHLITCPICTQKFKKQSKYEEHMKHHNDLLPFQCSEETCKKGFTTAGALRLHVDYAHTKKSSEIPCTVEGCRLLFPRLRLLTIHLKKVHNQTRVSAPRGDQPCRECGMVFRCPVALKKHMYKHTGEELPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHILTHTQEKQFKCHICDHATHTKRALDSHVKIVHEKVRNFACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKTHEKSMERALETYRQRHGEEDIAGAQVDADQLLKVCAESVATIPKDPRRVERVDLAQLAGTVVNPISTIQLPPSEMPTRTKFVQKEGMHLCPGCSQGFNNLGNMKRHYKSVHEKVKDFECRFCARRFANSQSLKQHEWIHTGEKPYECKHCGTHFRQEAALIRHQKVHDKRPPKPPKPHKEITDKARQKAILKCAHKRKAEALREEIAVVAKEELKDLEKQRALEKQHKTYEQYQAAAAAEQTHSKSTEGS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615718;
90% Identity: iTF_00481686;
80% Identity: -