Basic Information

Insect: Drosophila atripex
Gene Symbol: ken1
Assembly: GCA_035045925.1
Location: JAWNOP010000032.1:1907923-1910145[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00017 0.013 15.9 5.3 2 23 187 208 186 208 0.97

2 12 0.00081 0.063 13.8 0.1 1 23 214 239 214 239 0.93

3 12 0.11 8.2 7.1 0.1 3 23 248 271 246 271 0.92

4 12 0.0012 0.09 13.3 1.0 2 23 284 305 283 305 0.96

5 12 8.9e-06 0.00069 20.0 0.6 1 23 312 334 312 334 0.98

6 12 0.0053 0.41 11.2 0.1 1 23 340 362 340 362 0.98

7 12 0.014 1.1 9.9 4.0 1 23 368 391 368 391 0.97

8 12 0.0095 0.74 10.4 4.0 1 23 397 419 397 419 0.96

9 12 0.00055 0.042 14.3 3.7 2 23 426 447 425 447 0.96

10 12 0.00026 0.02 15.3 1.1 3 23 536 557 534 557 0.95

11 12 0.01 0.78 10.3 0.7 1 19 563 581 563 585 0.95

12 12 1.4e-06 0.00011 22.5 1.2 1 23 591 613 591 613 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00017	0.013	15.9	5.3	2	23	187	208	186	208	0.97
2	12	0.00081	0.063	13.8	0.1	1	23	214	239	214	239	0.93
3	12	0.11	8.2	7.1	0.1	3	23	248	271	246	271	0.92
4	12	0.0012	0.09	13.3	1.0	2	23	284	305	283	305	0.96
5	12	8.9e-06	0.00069	20.0	0.6	1	23	312	334	312	334	0.98
6	12	0.0053	0.41	11.2	0.1	1	23	340	362	340	362	0.98
7	12	0.014	1.1	9.9	4.0	1	23	368	391	368	391	0.97
8	12	0.0095	0.74	10.4	4.0	1	23	397	419	397	419	0.96
9	12	0.00055	0.042	14.3	3.7	2	23	426	447	425	447	0.96
10	12	0.00026	0.02	15.3	1.1	3	23	536	557	534	557	0.95
11	12	0.01	0.78	10.3	0.7	1	19	563	581	563	585	0.95
12	12	1.4e-06	0.00011	22.5	1.2	1	23	591	613	591	613	0.98

Sequence Information

Coding Sequence: ATGGACACCAGGGACACCAGGTACCGGGCGACCGGCCGCCGACTATGTCGCATTTGTCTTCTCGACTTGGAGCAGGCTTTTGGGCACGATTTGTTCGTGGAACCGGAGCTGGTTAAGAAATTCACAGTTTGCACTTCACTGGTGGCCGAAAAGCAGGATGGATATCCCAGTATCCTTTGCGAAAGATGCTATGGAAAGCTAAACGAGCTTCACGATTTCCGGGAATTGTGCTTGATTTCCAGGCAGCGCTTTAAAGAAATGCTAGTTTGTAATTTGGTGACTTCAATGGATGTATTTGAGCCTGTAAAGGAGGATTCTGAGACGGAGGAGCAAAGCGGTTTCGATCCCCTCTTAAATCATAAACTGGAAGTTATTGACAATGAAGAGGAGGTGTTCAAGATGCTCGAAACGGTGGATAAAGACCCGGAGGAGCATCGAATCCCGGACGAATCATCCAATAACGATGAGGATGAAGGCGAAGACGAGAACGAGAACGAAAAACCTCTGCCCAAGCTACAGCATAATCCCAATAGGGAGCGCCTTCGCCTCCATCTTATTACATGTCCCATCTGCCACCAAAAGTTCAAGAAACAATCAAAATACGAGGAGCACATGAAGCACCACAACGATTTGTTGCCTTTTCAGTGCTCGGAGGAAACATGCAAGAAAGGCTTCACCACTGCGGGTGCACTGCGTCTTCATGTTGACTATGCACATACGAAAAAATCCAGCGAGATTCCCTGCACCGTGGAGGGTTGCAGGCTGCTCTTCCCTCGTCTCCGTCTATTGACGATTCACCTGAAAAAAGTGCACAACCAGACAAGAGTGAGTGCTCCTCGTGGGAATCAACCTTGTCGCGAATGTGGGATGGTCTTCCGTTGCCCGGTGGCGCTAAAAAAACACATGTACAAGCACACGGGCGAAGAGCTGCCGTATCCGTGCAACATATGCGGCAAGGGCTTCCACATAAACAGTGCCTTAAAAAATCACCTTCTGCGACATGCCGGGATTAAGAACTACGTTTGCCCCTACTGTGGAGTCGGAAAAACCACCAGGCAGGAATGGAGCAAACATATCCTCACCCACACGCAGGAGAAGCAGTTCAAGTGCCACATCTGTGACCACGCCACCCACACAAAAAGGGCTTTGGACAGCCATGTGAAGATCGTCCACGAAAAGGTCAGAAACTTCGCCTGCCAATATTGCGGCAAGACTTTTGGTAAATCGCACGCTTGCAAAATTCATGAAATGACTCACACGGGGGAGAAGCGCTGCGAGTGTAAGgtttGCGGCAAGAAGTTCCTCTACACAGAGAGCCTGACCAAGCATCTAAAAACCCACGAGAAGAGCATGGAACGAGCTTTGGAAACCTATCGGCAGCGGCACGGCGAAGAAGACATTGCCGGAGCCCAGGTGGACGCTGATCAACTGCTAAAGGTTTGCGCTGAGTCTGTGGCGACCATACCCAAAGATCCACGGCGCGTGGAACGTGTTGATCTGGCCCAGCTGGCAGGGACGGTAGTTAATCCCATCTCTACGATCCAGCTGCCGCCAAGCGAGATGCCCACGCGAACGAGATTTGTCCAGAAGGAAGGCATGCACTTATGCCCAGGCTGCAGTCAAGGATTCAACAATTTGGGAAACATGAAGCGCCACTACAAGAGCGTCCACGAGAAGGTAAAAGACTTTGAATGCCGCTTCTGCGCTCGTCGCTTCGCCAACTCGCAGTCTTTGAAGCAGCACGAGTGGATTCATACAGGCGAGAAGCCGTATGAGTGCAAGAATTGCGGCACCCACTTCCGCCAGGAGGCGGCTCTCATCCGACACCAAAAGGTTCACGACAAGAGACCACCGAAGCCCCCAAAGCCACACAAGGAAATCACGGACAAGGCGCGCCAGAAGGCCATCCAGAAATGTGCCCGCAAGCGGAAGGCAGAAGCCCTCAGAGAGGAGATCGCCGTAGTGGCCAAAGAGGAGCTAAAAGATCTGGAGAAGCAGCGGGCACTTGAAAAGCAGCACAATACCTATGAACAGTAtcgggcagcagcagccgagcAAACGTATTCCAAGGCCACTGAGGGATCATAA
Protein Sequence: MDTRDTRYRATGRRLCRICLLDLEQAFGHDLFVEPELVKKFTVCTSLVAEKQDGYPSILCERCYGKLNELHDFRELCLISRQRFKEMLVCNLVTSMDVFEPVKEDSETEEQSGFDPLLNHKLEVIDNEEEVFKMLETVDKDPEEHRIPDESSNNDEDEGEDENENEKPLPKLQHNPNRERLRLHLITCPICHQKFKKQSKYEEHMKHHNDLLPFQCSEETCKKGFTTAGALRLHVDYAHTKKSSEIPCTVEGCRLLFPRLRLLTIHLKKVHNQTRVSAPRGNQPCRECGMVFRCPVALKKHMYKHTGEELPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHILTHTQEKQFKCHICDHATHTKRALDSHVKIVHEKVRNFACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKTHEKSMERALETYRQRHGEEDIAGAQVDADQLLKVCAESVATIPKDPRRVERVDLAQLAGTVVNPISTIQLPPSEMPTRTRFVQKEGMHLCPGCSQGFNNLGNMKRHYKSVHEKVKDFECRFCARRFANSQSLKQHEWIHTGEKPYECKNCGTHFRQEAALIRHQKVHDKRPPKPPKPHKEITDKARQKAIQKCARKRKAEALREEIAVVAKEELKDLEKQRALEKQHNTYEQYRAAAAEQTYSKATEGS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615718;
90% Identity: iTF_00476079; iTF_00477482; iTF_00550392;
80% Identity: -