Dmon005391.1
Basic Information
- Insect
- Drosophila monieri
- Gene Symbol
- -
- Assembly
- GCA_035047585.1
- Location
- JAWNPJ010000052.1:341452-344297[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 1.8 1.5e+02 3.3 1.7 2 23 140 162 139 162 0.94 2 13 0.00031 0.025 15.1 0.6 2 23 174 196 173 196 0.95 3 13 4.1e-06 0.00032 21.1 4.2 2 23 203 225 202 225 0.96 4 13 0.0094 0.75 10.5 9.0 2 23 443 464 443 464 0.97 5 13 1.7e-06 0.00013 22.3 2.9 1 23 470 493 470 493 0.95 6 13 0.00017 0.013 16.0 0.4 1 23 498 521 498 521 0.96 7 13 5.6e-05 0.0044 17.5 5.5 1 23 539 561 539 561 0.96 8 13 6.4e-05 0.0051 17.3 0.7 1 23 566 588 566 588 0.98 9 13 2.9e-05 0.0023 18.4 1.7 1 23 594 616 594 616 0.95 10 13 2.1e-05 0.0017 18.8 0.7 1 23 622 644 622 644 0.98 11 13 3e-07 2.4e-05 24.6 2.7 3 23 652 672 651 672 0.99 12 13 2.2e-08 1.8e-06 28.2 1.1 1 23 678 700 678 700 0.99 13 13 0.21 16 6.3 4.3 1 19 705 723 705 728 0.89
Sequence Information
- Coding Sequence
- ATGGCATCGCCCCATCCGCAGCCGGGCCCGGAACCGGAACAGGAGACGGGAATCCCGCCCCAGCCGGCGGGGCACGGAAAAGTGGATGCCGTGGACCCGGATCGCGTATGCCGTGTCTGCCTTAGGGATGCCTCCCTGGACGGAGAGCTGCACTTCATCTTCGCCGAGGCGGCCGTGGAGCAGGACGCCAACCTGGCCCGCATCCTTGAGGAGTGCACAGTCCATCCATGCGAAAGGCAGGACGGGATGCCAGCGCACATGTGCGGTTCTTGTGCGGAGGCAGCGCGCAGCGCCTACCGTTTCAAGCGGAACGCGGAGCGCTCTTATTGCTCGCTGGTAGCACTCCTGGGACGGTCTCCCCAAGTCAAGACTTCCGGCTCCGAGGCGTCCACCCAGACGGAGCAGGTGGCCCTGTTGTCGTGCGAGTTGTGCCACGACAAGTTCCTGAACAGCATGGATCTCCGCCTGCACCGGAACCGTGTCCACCGGACGGCAAGGGAGGACAAGGAAGAGGAGCTGAAGTGCAAGTTCTGCCCCGAGAGGTTCCCCCAACTCCGGCAGCTGCGCATCCACCTGGCAAAGAGCCACGACCAGACCGCTCGCCTCCAGTGCGGCCACTGCCCGAGGACCTTCACCCGGAGCGACCATATGCTGCGCCACATGCGCAACATGCACAACCGCTCGCAGGACGATCTTCCGTCAGCCTGGCCGTCGGCCGACCACGATGAGACGACCATGGAGGACGGGGACGGTGACGAACTGGTCGCCGCCGAGGTCCTGCTCAACGAGGAGGGCGATGACCACGAAGGATCAGCTGCCCTAGAGTGCAATACCAACCCAATCTCCAGCaatgaggaggaggacgatgaCAACGACGAGGCCAAGCAGGCGCTATGGTTGCACATTAAGCCGGAGCCCTGCCTGGAGGCTGAGGAGGTCGACCTGGTCGCCCAACTGAACCTCGAGAAGAAGCGTCGGCGCCGGGAGAAGGCTGTAGTAGCAGCCGAAGCCTCTGGGGAAGCTCATGTGAAGAGCGAACCCAGCGGTGACTCGCAGATGAGCATCAAGGTGGAGCGGGCGGGCGACGAAGATGCCTTCATGGGCGGGGAGGACTTCCTGGAGCATCTGCGGGCCGCCGGGGAACTGCCGCTCAGCGACGACGACCAGTTCTACAACTACGTCGAAGAGGAGAGCTGTctggacgacgacgacgacgaggaggatgacgaaggcgatggcgatggcgaggATGACGACGACGGGACGAAAGGGAAAGCGACGGCGCCGCCGCAAAAAGAGGGCTCGCCCACCTCCAATCCGGAGAACCGGTGCGAGGTGTGCCAGCGCACATTTTCGCGCCACTGCCACTTGCTGCGCCACAAGCTGTCGCATCTGGAGAAGAAGCCCCACAACTGCCCGCACTGCCCGAAGGCGTTTGCGCGCAGCGATCACCTGAAGGCGCACGTCCAAAGCCTGCACAGCAACAAGGAGCACAAGTGCAGTCTCTGCGAGGCGGCGTTCGCTCGTCCCGACGCCCTGGAGCGACACAAGCTGAGCAAGCACAACGGCGAGGGCCTGGAGCCGGGCAGCGAACTGAAGATGCAGCTGGCGGAGCATACCTGCGAGTACTGTTCGAAGCGGTTCTCCAGCAAGACCTACCTGCGCAAGCACACCCTGCTCCACACCGATTTTCTGTACGCCTGCAAGAGCTGCGACGAAACGTTCCGGGAGCGGGCGCAGTTGCGGGAGCACGAGAAGACCCACACCGGGCAGAGGAACTTCCTTTGTTGCATTTGCGGCGATAGCTTTGCCCGAAACGACTACCTCCGCGTCCATATGCGGCGCCACAACGGCGAGAAGCCCTACAAGTGCCGTTACTGCGTCAAGGCCTTCCCCCGGGCCACCGATCTCAAGGTTCACGAGCGCTACCATACGGGCACCAAGCCAAATCTGTGCAACACCTGCGGCAAGAGCTTCCATCGGGCCTACAACCTGACCATCCACATGCGCACCCACACCGGTGAACGGCCATACAAGTGCGACCAGTGCCCCAAGAGCTTCACGCAGAGCAACGACCTCAAGGCGCACATCCGTCGGCATACGGGCGAGCGCTACAAGTGTCCGCACTGCGACACCTACTTCCTGCAGCTGTACAACATGCGCAACCACTGCCTCAGCGCCCACAACAAGCACATCGAGACGAAGACGGGTCGCCTCCAGCGAACGGGTCTGCTGGAAGAGAGCGGGCAGTCGCATCTCACTACGGTGGTGATGCCGCCAGCGCGCTATCCCGCCGGCTCTGATCCCCAGCTGTCGGCCGCAATGGGAGCCGATaactcctcctccaccacaGTCATCCACTCTCCGGGCGCATATCAGAATAGTGGCGTTGCTCCAGGGGTTCTGGCACCGGGAAACACTTCGTCGGCGGCGGCGGGAAATACTCTGGACGGGAACAGCTTCGCGCCAACGGCGGTGAATGCGAGCGCTCCGTTTGGCGCCTTCAACTTCCCTCCCGTCGTGATGGCGCATCTCATGTACAACCACGCGGGCAGCAGCCAGCACAGCCAGAGCGGCAGCGACACCGCCAAATAG
- Protein Sequence
- MASPHPQPGPEPEQETGIPPQPAGHGKVDAVDPDRVCRVCLRDASLDGELHFIFAEAAVEQDANLARILEECTVHPCERQDGMPAHMCGSCAEAARSAYRFKRNAERSYCSLVALLGRSPQVKTSGSEASTQTEQVALLSCELCHDKFLNSMDLRLHRNRVHRTAREDKEEELKCKFCPERFPQLRQLRIHLAKSHDQTARLQCGHCPRTFTRSDHMLRHMRNMHNRSQDDLPSAWPSADHDETTMEDGDGDELVAAEVLLNEEGDDHEGSAALECNTNPISSNEEEDDDNDEAKQALWLHIKPEPCLEAEEVDLVAQLNLEKKRRRREKAVVAAEASGEAHVKSEPSGDSQMSIKVERAGDEDAFMGGEDFLEHLRAAGELPLSDDDQFYNYVEEESCLDDDDDEEDDEGDGDGEDDDDGTKGKATAPPQKEGSPTSNPENRCEVCQRTFSRHCHLLRHKLSHLEKKPHNCPHCPKAFARSDHLKAHVQSLHSNKEHKCSLCEAAFARPDALERHKLSKHNGEGLEPGSELKMQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCDETFRERAQLREHEKTHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDTYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLEESGQSHLTTVVMPPARYPAGSDPQLSAAMGADNSSSTTVIHSPGAYQNSGVAPGVLAPGNTSSAAAGNTLDGNSFAPTAVNASAPFGAFNFPPVVMAHLMYNHAGSSQHSQSGSDTAK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00615033;
- 90% Identity
- iTF_00481668; iTF_00476059; iTF_00477464;
- 80% Identity
- -