Basic Information

Insect: Drosophila mimica
Gene Symbol: zfh1
Assembly: GCA_037043585.1
Location: JBAMBE010000618.1:271338-276664[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.9e-05 0.0019 18.5 1.0 1 23 152 174 152 174 0.97

2 15 0.00089 0.058 13.8 1.2 3 23 182 202 180 202 0.94

3 15 9.7e-05 0.0063 16.9 0.1 1 23 377 399 377 399 0.98

4 15 0.00033 0.022 15.2 0.9 1 23 405 427 405 427 0.98

5 15 0.00012 0.0077 16.6 2.3 1 23 459 482 459 482 0.94

6 15 0.012 0.76 10.3 3.0 1 23 535 557 535 557 0.94

7 15 0.00072 0.046 14.1 0.4 1 23 563 586 563 586 0.98

8 15 0.028 1.8 9.1 0.4 3 19 595 611 594 612 0.95

9 15 0.00017 0.011 16.1 5.6 1 23 621 643 621 643 0.97

10 15 0.044 2.8 8.5 1.2 2 23 649 670 648 670 0.96

11 15 9.9e-06 0.00064 20.0 1.0 1 23 679 701 679 701 0.98

12 15 0.0011 0.073 13.5 0.1 3 23 709 729 707 729 0.97

13 15 6e-05 0.0039 17.5 0.5 1 23 735 757 735 758 0.95

14 15 0.051 3.3 8.3 0.4 1 23 768 790 768 790 0.97

15 15 0.00018 0.012 16.0 0.5 1 23 1305 1327 1305 1327 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.9e-05	0.0019	18.5	1.0	1	23	152	174	152	174	0.97
2	15	0.00089	0.058	13.8	1.2	3	23	182	202	180	202	0.94
3	15	9.7e-05	0.0063	16.9	0.1	1	23	377	399	377	399	0.98
4	15	0.00033	0.022	15.2	0.9	1	23	405	427	405	427	0.98
5	15	0.00012	0.0077	16.6	2.3	1	23	459	482	459	482	0.94
6	15	0.012	0.76	10.3	3.0	1	23	535	557	535	557	0.94
7	15	0.00072	0.046	14.1	0.4	1	23	563	586	563	586	0.98
8	15	0.028	1.8	9.1	0.4	3	19	595	611	594	612	0.95
9	15	0.00017	0.011	16.1	5.6	1	23	621	643	621	643	0.97
10	15	0.044	2.8	8.5	1.2	2	23	649	670	648	670	0.96
11	15	9.9e-06	0.00064	20.0	1.0	1	23	679	701	679	701	0.98
12	15	0.0011	0.073	13.5	0.1	3	23	709	729	707	729	0.97
13	15	6e-05	0.0039	17.5	0.5	1	23	735	757	735	758	0.95
14	15	0.051	3.3	8.3	0.4	1	23	768	790	768	790	0.97
15	15	0.00018	0.012	16.0	0.5	1	23	1305	1327	1305	1327	0.98

Sequence Information

Coding Sequence: ATGAACAATCCGGACTATGGCGGCATCCAGTGGATACAGCATGAAAGCAGCGCCGTCGTCGACGACAGCGAAACAGAGATGACAGCAGCCTATTTGGTCAACGCTGCCGCGAATGGAAGCATTTCCAACGATGACGATCTCGATCATATGGCAGCCGAGAATCTCATCTTTATGGCACGCGACGGCCAACTGAGCGAAATCATCGCCGCAAATGAGGCAaatggcggcagcagcacagTGCTAATCGCGGAGAGCGACGGAAATAACGGTGTGGAATACGCCGAGTCCTTTGACGATGATGCGCAGGTCGTCACCGAGGAGATTATCACAGATGATTGGGTCCAGCATCAGGGCGCAGAGCGtgTGGAAATTGCCGCTGAGCAAATcgctggcagcggcagctcCCAGGAGCTGTTGGACATGCAACAGAATGAATATATGGCGATGCGTCCATATCCCTGCGACTTTTGCAGTCGACGCTTTCGCAAGAAGGCCAGCCTCAACAATCATATGCTTGCGCATCAGAATGATCGTCCGCATCTTTGCAAGCTGTGCGGGGCCCGTTTCTCGCGACGCGCGGAGCTCATCAGTCACTTCAAGGCGCATGCGGAGGCCCAGGTGGCCGCCGATGAAGAGGCAGCTGCGGCAGCCATTAAATTtgagccgcaacagcagctgcaacagcagcaacagcgacaaatCGAGGATCACTTCTATGAGCATGAATGGCCGCTGTATCAGGAACAAGAGCAGGCGCAGGAGCTGGAACAGGTcgaggagcagctggagcagatcgagaaacagcaacagcagcaactggagcaccatcagcagctgttgcaacaaTCGGTTGCACCACCAACCGCTGCCCGAGGACGCATCAGTCGCTTAAAGCTCAAGGAGGAGAGCTCGCAATACATTGTGATTGCCTCCGATAATCCGGAGACGGAGTTGCCTCAATACATGCATAGCGAGGCGAATTGCGATCAATCGCTttccaccaacaacaaccaactcCAATCAACGTCATCCGAtgatgctgcaactgctgcggctgctgctgctgctgccgatggGGCACAGGGGCACGCAACACTGCGCTTTCCCGTGCTCGACGAGAGCAAACCCTTCGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCGCTCGTCTCCCACATCAAGAATCATCGGGTGGATTCGCCGTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAATTACAGTCTGCAGGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAATTCGGAATACGATCCGGCATCGGCGGGCGAGGAGGATACGGCGAGTGAATCGGAAGCGGAACAGCTTTACGGTGTTTTCTACTGCGGCGAATGCGGCATCTCCTTTCACCGGCAGGATTTGTTGCGGCgccacagcaaacagcagcacagCAAGCAGCTGGCTGCAGCAACGActggtggcagcaacaacaacaacaacaacagtgtggcaactgcaacagcaacggatGCAGTaggtgctgcagctgcagctgcaactgatgCAGATGCCGATGCTGATGCTAATGATGCCAAAGATGCGCCACATTGTTGCCACACGTGCGGCAAATCATTTCCCAGCGTACTCAAACTGCTCGCCCATGCCGAAATCCACAAACGCTTCCCGCCATTCAAATGTGTCCTGTGCGGAGTCAGCTTCTACGATGAGCAGGCGATAAAGCGGCACCTGAACACGCGGCATCCGCACGAGCTGAAGCCCAAttcgtgtgtgttgtgtggcaAGGAGTGTCGCGATCGGAAGGCGCTGATCAAACATGCGTGGGATCATTCGCGGGAGAAGTGCCACTCGTGCTCCAAGTGTGGCAAGAATTTCCACAACAAGGCGCGCCTGAAGCGACACATGGCATCGCATCGCGACAAGTCCGTCGTGTGCGAAGTGTGCCACGAGGAGTTCCCTGATGGACGCACCTTGTCCAATCATCGGCATTCCCACAGCACAACGTCGCCGGGCAAACTATTCCCATGCCACGAGTGCGGCAAGACTTTTGGGTCGCGCAGCTCGCAGCAGATTCATGTGCGCATCCACACGGGCGAAAGGCCCTACGGTTGTCGCTACTGCTGGAAGGCCTTCGCCGATGGCGGCACTCTCCGCAAACACGAACGCATCCACACGGGCGAGAAGCCCTATGCCTGCTCCGTCTGTCCGCGTGCTTTCAACCAGCGTGTCGTCTTGCGGGAACACATCCGCTCGCATCACTCCGGTCTGGATGCGGCGCGTGGCACGTACCATTGCACGGTCTGCTCCGCGGATTTGAGCTCATCGAATGACCTCATCCAGCACCTCATCCAGCACAGTGATACGAATACAGCCAAACAGCGACAGCCAATTACTGGTCCACGTAAATACAAACGACGCCGGAAACTGCAGCCGCATGAGATTGCGCACATGCGTGCCGAGCACAAGGCTGGTGGCGGCGGCGATGGCGAGGCTGGCGAGGAGGAGGATTATGGCAGCGACTTGGACTACTGCGATTTGGATGTGGAGAATGTGGATGAGTTGCTGCAGGAGGCAACCTCAgagccgccaccaccacccaccaaaAAAGCGAAACGCAAACGCAAAGCGCCAATTAAAAGCGGCGATGAGCAAAGATTGTGGGACGAGAAATTTCTGCAGCAGGCGAACAATGGGAATAGCGATGAGGCCTACAAGAGTTTCTTTCAAATGGACTCGCTGGTCGTGGTCAATGATCAAGCGCTGCAACCCGTTGATGCTGGTGTTGCCGCGACCAAGTTGCAGCAGGCGGAGATTCAGGAGCAAACGCTGAAGACAGGCAATCGTAGCAGCAAAAGAAGGGCAGGCAAAGTTAGCGCAGAAGGAGCAGCCGGAGGAGGAACAGCAGGCGGAGGAGCATCAGGAGGAACTGCTGCTCCTCCACGTCCCCGCATGATACACACGGCCAAGTCGAAGCAGACAACGTCAAGGAAGTCCCGCACAAGGAGTTATATCACACGCACCAGCAccaatgagcagcagcagggtgGAGGAGCAAGTGGAGGAAGCCTCATCAAATCCCGCATTGTTGATGACTATGAGATTATCTCACCGGCCACACAGCCACCCAATCAGATCAGTTCCAGTCCGCTGCACATCaaacaggagcaggaacatcaacagcatcatcatcatcaccatcaacagcagcagcagcatcagcagcagcagcgagtccAACTGCTCTTCGATGACAGCCATCTGCTCATCGAATCGGGCCTGTTGCGTGAGAAGACCTACGAGAAATATAATCCCAGCATTGTTCAAGATCTCGAGGAGATTTTGCGTAGTCCCCCGAAGCATGAGCGGAACGATCGACGGCTGCGCTTCACCAGCGAATCGTCGACGACGCCACAATTTCTGCCCGGAGAGGAGGAGGAACAGCATCTCATCAAGATCGAGCCCACATCGCCGGATCTCCGGGAAATGGTCGAgagccagcagccagccacACTGCCCACATCCTCCTCCGTCTGCTCAACGGCGGCACGCACTTCCCGCCACCTGCGACAGCTGACTGCCAATGGTCCCCCCAGTTCCATTTCCACTTCCAGTTCCAGTGCCGCTTCCAGTACGCGAGCCGCTTCCAAGCGGAATGCAAGCAAACAACTTTCCAAGAAATCCACTTCAAATAGCAACAAGGGCAACTCCTCAACGTCTTATCTCAGCTATGGCGTCGACTCCTAtaatgtgggcgtggcagccagTGCCAATAGCTCCTCGGATGTTAGTTCCGGTTTCTTCTCAATTTCCGAGGTCGTCTCGGCGGCGGATGCAGCCGATGCAGCTGCgaaggcggcggcggcagcagcctGCAAAACGGAGCGAAGAACGCGCTGCTTTGAGTGTGAAATGTGCTCCTACAATTTTCCAGATCGTGCTCAGCTGCTGgaacacatgcatatacacatcTAG
Protein Sequence: MNNPDYGGIQWIQHESSAVVDDSETEMTAAYLVNAAANGSISNDDDLDHMAAENLIFMARDGQLSEIIAANEANGGSSTVLIAESDGNNGVEYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGSGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQVAADEEAAAAAIKFEPQQQLQQQQQRQIEDHFYEHEWPLYQEQEQAQELEQVEEQLEQIEKQQQQQLEHHQQLLQQSVAPPTAARGRISRLKLKEESSQYIVIASDNPETELPQYMHSEANCDQSLSTNNNQLQSTSSDDAATAAAAAAAADGAQGHATLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGEEDTASESEAEQLYGVFYCGECGISFHRQDLLRRHSKQQHSKQLAAATTGGSNNNNNNSVATATATDAVGAAAAAATDADADADANDAKDAPHCCHTCGKSFPSVLKLLAHAEIHKRFPPFKCVLCGVSFYDEQAIKRHLNTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAARGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKAGGGGDGEAGEEEDYGSDLDYCDLDVENVDELLQEATSEPPPPPTKKAKRKRKAPIKSGDEQRLWDEKFLQQANNGNSDEAYKSFFQMDSLVVVNDQALQPVDAGVAATKLQQAEIQEQTLKTGNRSSKRRAGKVSAEGAAGGGTAGGGASGGTAAPPRPRMIHTAKSKQTTSRKSRTRSYITRTSTNEQQQGGGASGGSLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHHHHHHQQQQQHQQQQRVQLLFDDSHLLIESGLLREKTYEKYNPSIVQDLEEILRSPPKHERNDRRLRFTSESSTTPQFLPGEEEEQHLIKIEPTSPDLREMVESQQPATLPTSSSVCSTAARTSRHLRQLTANGPPSSISTSSSSAASSTRAASKRNASKQLSKKSTSNSNKGNSSTSYLSYGVDSYNVGVAASANSSSDVSSGFFSISEVVSAADAADAAAKAAAAAACKTERRTRCFECEMCSYNFPDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00542584;
90% Identity: iTF_00499722;
80% Identity: -